메뉴 건너뛰기




Volumn 6, Issue B, 2004, Pages

Oral direct thrombin inhibition for anticoagulation in coronary artery disease - Focus on the ESTEEM trial

Author keywords

Anticoagulation; Coronary arterial disease; ESTEEM; Myocardial infarction; Oral direct thrombin inhibitors; Ximelagatran

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; LIVER ENZYME; PLACEBO; THROMBIN INHIBITOR; XIMELAGATRAN;

EID: 1942520428     PISSN: 1520765X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ehjsup.2004.01.015     Document Type: Review
Times cited : (3)

References (32)
  • 1
    • 0033211205 scopus 로고    scopus 로고
    • The pathogenesis and spectrum of acute coronary syndromes: From plaque formation to thrombosis
    • Patel VB, Topol EJ. The pathogenesis and spectrum of acute coronary syndromes: from plaque formation to thrombosis. Cleve Clin J Med 1999;66:561-71.
    • (1999) Cleve Clin J Med , vol.66 , pp. 561-571
    • Patel, V.B.1    Topol, E.J.2
  • 2
    • 0035902456 scopus 로고    scopus 로고
    • Current concepts of the pathogenesis of the acute coronary syndromes
    • Libby P. Current concepts of the pathogenesis of the acute coronary syndromes. Circulation 2001;104:365-72.
    • (2001) Circulation , vol.104 , pp. 365-372
    • Libby, P.1
  • 4
    • 0037065502 scopus 로고    scopus 로고
    • Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients
    • Antithrombotic Trialists' Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 2002;324:71-86.
    • (2002) BMJ , vol.324 , pp. 71-86
  • 6
    • 0035125405 scopus 로고    scopus 로고
    • Heparin and low-molecular-weight heparin: Mechanisms of action, pharmacokinetics, dosing, monitoring, efficacy, and safety
    • Hirsh J, Warkentin TE, Shaughnessy SG et al. Heparin and low-molecular-weight heparin: mechanisms of action, pharmacokinetics, dosing, monitoring, efficacy, and safety. Chest 2001;119:64S-94S.
    • (2001) Chest , vol.119
    • Hirsh, J.1    Warkentin, T.E.2    Shaughnessy, S.G.3
  • 7
    • 0037948571 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia
    • Warkentin TE. Heparin-induced thrombocytopenia. Curr Hematol Rep 2002;1:63-72.
    • (2002) Curr Hematol Rep , vol.1 , pp. 63-72
    • Warkentin, T.E.1
  • 8
    • 0035125405 scopus 로고    scopus 로고
    • Heparin and low-molecular-weight heparin: Mechanisms of action, pharmacokinetics, dosing, monitoring, efficacy, and safety
    • Hirsh J, Warkentin TE, Shaughnessy SG et al. Heparin and low-molecular-weight heparin: mechanisms of action, pharmacokinetics, dosing, monitoring, efficacy, and safety. Chest 2001;119:64S-94S.
    • (2001) Chest , vol.119
    • Hirsh, J.1    Warkentin, T.E.2    Shaughnessy, S.G.3
  • 9
    • 0030764772 scopus 로고    scopus 로고
    • Reactivation of the coagulation system: Rationale for long-term antithrombotic treatment
    • Kontny F. Reactivation of the coagulation system: rationale for long-term antithrombotic treatment. Am J Cardiol 1997;80:55E-60E.
    • (1997) Am J Cardiol , vol.80
    • Kontny, F.1
  • 10
    • 0141924393 scopus 로고    scopus 로고
    • Coagulation activation and long-term outcome in acute coronary syndromes
    • Ardissino D, Merlini PA, Bauer KA et al. Coagulation activation and long-term outcome in acute coronary syndromes. Blood 2003;102:2731-5.
    • (2003) Blood , vol.102 , pp. 2731-2735
    • Ardissino, D.1    Merlini, P.A.2    Bauer, K.A.3
  • 11
    • 0028962819 scopus 로고
    • Rebound increase in thrombin generation and activity after cessation of intravenous heparin in patients with acute coronary syndromes
    • Granger CB, Miller JM, Bovill EG et al. Rebound increase in thrombin generation and activity after cessation of intravenous heparin in patients with acute coronary syndromes. Circulation 1995;91:1929-35.
    • (1995) Circulation , vol.91 , pp. 1929-1935
    • Granger, C.B.1    Miller, J.M.2    Bovill, E.G.3
  • 13
    • 0026736119 scopus 로고
    • Reactivation of unstable angina after the discontinuation of heparin
    • Theroux P, Waters D, Lam J et al. Reactivation of unstable angina after the discontinuation of heparin. N Engl J Med 1992;327:141-5.
    • (1992) N Engl J Med , vol.327 , pp. 141-145
    • Theroux, P.1    Waters, D.2    Lam, J.3
  • 14
    • 0025146426 scopus 로고
    • Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors
    • Weitz JI, Hudoba M, Massel D et al. Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors. J Clin Invest 1990;86:385-91.
    • (1990) J Clin Invest , vol.86 , pp. 385-391
    • Weitz, J.I.1    Hudoba, M.2    Massel, D.3
  • 15
    • 0038344806 scopus 로고    scopus 로고
    • A novel approach to thrombin inhibition
    • Weitz JI. A novel approach to thrombin inhibition. Thromb Res 2003;109(Suppl 1):S17-22.
    • (2003) Thromb Res , vol.109 , Issue.SUPPL. 1
    • Weitz, J.I.1
  • 16
    • 0034573085 scopus 로고    scopus 로고
    • The mechanism of action of thrombin inhibitors
    • Bates SM, Weitz JI. The mechanism of action of thrombin inhibitors. J Invasive Cardiol 2000;12(Suppl F):27F-32F.
    • (2000) J Invasive Cardiol , vol.12 , Issue.SUPPL. F
    • Bates, S.M.1    Weitz, J.I.2
  • 17
    • 0035712804 scopus 로고    scopus 로고
    • Pharmacokinetics of an emerging new class of anticoagulant/ antithrombotic drugs. A review of small-molecule thrombin inhibitors
    • Hauptmann J. Pharmacokinetics of an emerging new class of anticoagulant/antithrombotic drugs. A review of small-molecule thrombin inhibitors. Eur J Clin Pharmacol 2002;57:751-8.
    • (2002) Eur J Clin Pharmacol , vol.57 , pp. 751-758
    • Hauptmann, J.1
  • 18
    • 0035251672 scopus 로고    scopus 로고
    • The direct thrombin inhibitor melagatran and its oral prodrug H 376/95: Intestinal absorption properties, biochemical and pharmacodynamic effects
    • Gustafsson D, Nystrom J, Carlsson S et al. The direct thrombin inhibitor melagatran and its oral prodrug H 376/95: intestinal absorption properties, biochemical and pharmacodynamic effects. Thromb Res 2001;101:171-81.
    • (2001) Thromb Res , vol.101 , pp. 171-181
    • Gustafsson, D.1    Nystrom, J.2    Carlsson, S.3
  • 19
    • 0033008172 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of melagatran, a novel synthetic LMW thrombin inhibitor, in patients with acute DVT
    • Eriksson H, Eriksson UG, Frison L et al. Pharmacokinetics and pharmacodynamics of melagatran, a novel synthetic LMW thrombin inhibitor, in patients with acute DVT. Thromb Haemost 1999;81:358-63.
    • (1999) Thromb Haemost , vol.81 , pp. 358-363
    • Eriksson, H.1    Eriksson, U.G.2    Frison, L.3
  • 20
    • 0037372498 scopus 로고    scopus 로고
    • Absorption, distribution, metabolism, and excretion of ximelagatran, an oral direct thrombin inhibitor, in rats, dogs, and humans
    • Eriksson UG, Bredberg U, Hoffmann KJ et al. Absorption, distribution, metabolism, and excretion of ximelagatran, an oral direct thrombin inhibitor, in rats, dogs, and humans. Drug Metab Dispos 2003;31:294-305.
    • (2003) Drug Metab Dispos , vol.31 , pp. 294-305
    • Eriksson, U.G.1    Bredberg, U.2    Hoffmann, K.J.3
  • 21
    • 0038526281 scopus 로고    scopus 로고
    • No influence of ethnic origin on the pharmacokinetics and pharmacodynamics of melagatran following oral administration of ximelagatran, a novel oral direct thrombin inhibitor, to healthy male volunteers
    • Johansson LC, Andersson M, Fager G et al. No influence of ethnic origin on the pharmacokinetics and pharmacodynamics of melagatran following oral administration of ximelagatran, a novel oral direct thrombin inhibitor, to healthy male volunteers. Clin Pharmacokinet 2003;42:475-84.
    • (2003) Clin Pharmacokinet , vol.42 , pp. 475-484
    • Johansson, L.C.1    Andersson, M.2    Fager, G.3
  • 22
    • 0037256123 scopus 로고    scopus 로고
    • Influence of age on the pharmacokinetics and pharmacodynamics of ximelagatran, an oral direct thrombin inhibitor
    • Johansson LC, Frison L, Logren U et al. Influence of age on the pharmacokinetics and pharmacodynamics of ximelagatran, an oral direct thrombin inhibitor. Clin Pharmacokinet 2003;42:381-92.
    • (2003) Clin Pharmacokinet , vol.42 , pp. 381-392
    • Johansson, L.C.1    Frison, L.2    Logren, U.3
  • 23
    • 0037512328 scopus 로고    scopus 로고
    • No influence of obesity on the pharmacokinetics and pharmacodynamics of melagatran, the active form of the oral direct thrombin inhibitor ximelagatran
    • Sarich TC, Teng R, Peters GR et al. No influence of obesity on the pharmacokinetics and pharmacodynamics of melagatran, the active form of the oral direct thrombin inhibitor ximelagatran. Clin Pharmacokinet 2003;42:485-92.
    • (2003) Clin Pharmacokinet , vol.42 , pp. 485-492
    • Sarich, T.C.1    Teng, R.2    Peters, G.R.3
  • 24
    • 0042623846 scopus 로고    scopus 로고
    • Ximelagatran, an oral direct thrombin inhibitor, has a low potential for cytochrome P450-mediated drug-drug interactions
    • Bredberg E, Andersson TB, Frison L et al. Ximelagatran, an oral direct thrombin inhibitor, has a low potential for cytochrome P450-mediated drug-drug interactions. Clin Pharmacokinet 2003;42:765-77.
    • (2003) Clin Pharmacokinet , vol.42 , pp. 765-777
    • Bredberg, E.1    Andersson, T.B.2    Frison, L.3
  • 25
    • 0037048939 scopus 로고    scopus 로고
    • Ximelagatran and melagatran compared with dalteparin for prevention of venous thromboembolism after total hip or knee replacement: The METHRO II randomised trial
    • Eriksson BI, Bergqvist D, Kalebo P et al. Ximelagatran and melagatran compared with dalteparin for prevention of venous thromboembolism after total hip or knee replacement: the METHRO II randomised trial. Lancet 2002;360:1441-7.
    • (2002) Lancet , vol.360 , pp. 1441-1447
    • Eriksson, B.I.1    Bergqvist, D.2    Kalebo, P.3
  • 26
    • 0037108825 scopus 로고    scopus 로고
    • Ximelagatran versus warfarin for the prevention of venous thromboembolism after total knee arthroplasty. A randomized, double-blind trial
    • Francis CW, Davidson BL, Berkowitz SD et al. Ximelagatran versus warfarin for the prevention of venous thromboembolism after total knee arthroplasty. A randomized, double-blind trial. Ann Intern Med 2002;137:648-55.
    • (2002) Ann Intern Med , vol.137 , pp. 648-655
    • Francis, C.W.1    Davidson, B.L.2    Berkowitz, S.D.3
  • 27
    • 12244263507 scopus 로고    scopus 로고
    • The express study: Preliminary results
    • Glynn O. The express study: preliminary results. Int J Clin Pract 2003;57:57-9.
    • (2003) Int J Clin Pract , vol.57 , pp. 57-59
    • Glynn, O.1
  • 28
    • 0345414673 scopus 로고    scopus 로고
    • Stroke prevention with the oral direct thrombin inhibitor ximelagatran compared with warfarin in patients with non-valvular atrial fibrillation (SPORTIF III): Randomised controlled trial
    • Executive steering committee on behalf of the SPORTIF III Investigators
    • Olsson SB. Executive steering committee on behalf of the SPORTIF III Investigators. Stroke prevention with the oral direct thrombin inhibitor ximelagatran compared with warfarin in patients with non-valvular atrial fibrillation (SPORTIF III): randomised controlled trial. Lancet 2003;362:1691-8.
    • (2003) Lancet , vol.362 , pp. 1691-1698
    • Olsson, S.B.1
  • 29
    • 0041829444 scopus 로고    scopus 로고
    • Oral ximelagatran for secondary prophylaxis after myocardial infarction: The ESTEEM randomised controlled trial
    • Wallentin L, Wilcox RG, Weaver WD et al. Oral ximelagatran for secondary prophylaxis after myocardial infarction: the ESTEEM randomised controlled trial. Lancet 2003;362:789-97.
    • (2003) Lancet , vol.362 , pp. 789-797
    • Wallentin, L.1    Wilcox, R.G.2    Weaver, W.D.3
  • 30
    • 0030764772 scopus 로고    scopus 로고
    • Reactivation of the coagulation system: Rationale for long-term antithrombotic treatment
    • Kontny F. Reactivation of the coagulation system: rationale for long-term antithrombotic treatment. Am J Cardiol 1997;80:55E-60E.
    • (1997) Am J Cardiol , vol.80
    • Kontny, F.1
  • 31
    • 0037179656 scopus 로고    scopus 로고
    • Warfarin, aspirin, or both after myocardial infarction
    • Hurlen M, Abdelnoor M, Smith P et al. Warfarin, aspirin, or both after myocardial infarction. N Engl J Med 2002;347:969-74.
    • (2002) N Engl J Med , vol.347 , pp. 969-974
    • Hurlen, M.1    Abdelnoor, M.2    Smith, P.3
  • 32
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Yusuf S, Zhao F, Mehta SR et al. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001;345:494-502.
    • (2001) N Engl J Med , vol.345 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.