Two modes of polyamine block regulating the cardiac inward rectifier K+ current IK1 as revealed by a study of the Kir2.1 channel expressed in a human cell line

Journal of Physiology

Volumn 556, Issue 1, 2004, Pages 61-78

  Ishihara, Keiko ^a   Ehara, Tsuguhisa ^a  

^a SAGA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; POLYAMINE; POTASSIUM ION; SPERMIDINE; SPERMINE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1;

ARTICLE; CELL MEMBRANE CONDUCTANCE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; MOLECULAR MECHANICS; POTASSIUM CONDUCTANCE; POTASSIUM CURRENT; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; STEADY STATE; CELL LEVEL; CHANNEL GATING; CHORD CONDUCTANCE VOLTAGE RELATIONSHIP; CONFORMATIONAL TRANSITION; INWARD RECTIFIER POTASSIUM CURRENT; MOLECULAR DYNAMICS; OUTWARD CURRENT VOLTAGE RELATIONSHIP; PHYSICAL PARAMETERS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENSITIVITY ANALYSIS;

CELL LINE; CYTOPLASM; DRUG SYNERGISM; ELECTRIC CONDUCTIVITY; HOMEOSTASIS; HUMANS; MODELS, BIOLOGICAL; MYOCARDIUM; POTASSIUM CHANNELS, INWARDLY RECTIFYING; REACTION TIME; SPERMIDINE; SPERMINE;

EID: 1942517923     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2003.055434     Document Type: Article

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