Molecular cloning and characterization of human homeobox gene Nkx3.1 promoter

Acta Biochimica et Biophysica Sinica

Volumn 36, Issue 1, 2004, Pages 64-67

  Jiang, An Li ^a   Zhang, Jian Ye ^a   Young, Charles ^b   Hu, Xiao Yan ^a   Wang, Yong Mei ^a,c   Liu, Zhi Fang ^a   Hao, Mei Lan ^a  

^a SHANDONG UNIVERSITY   (China)

^b MAYO CLINIC   (United States)

^c Department of Biochemistry   (Thailand)

Author keywords

Deletion mutagenesis; Homeobox gene Nkx3.1; LNCaP cell line; Promoter

Indexed keywords

LUCIFERASE;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; ENZYME ASSAY; EXPRESSION VECTOR; GENE; GENE ACTIVITY; GENE CONSTRUCT; GENE DELETION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC TRANSFECTION; HOMEOBOX; HUMAN; HUMAN CELL; MALE; MOLECULAR CLONING; NKX3.1 GENE; POLYMERASE CHAIN REACTION; PROMOTER REGION; PROSTATE CARCINOMA; PROTEIN FOLDING; REPORTER GENE; SEQUENCE ANALYSIS; TATA BOX; TRANSCRIPTION REGULATION;

RENILLA; VECTORS;

EID: 1942503338     PISSN: 05829879     EISSN: None     Source Type: Journal    
DOI: 10.1093/abbs/36.1.64     Document Type: Article

References (9)

1. Sciavolino PJ, Abrams EW, Yang L, Austenberg LP, Shen MM, Abate-Shen C. Tissue-specific expression of murine Nkx3.1 in the male urogenital system. Dev Dyn, 1997, 209: 127-138
2. Bieberich CJ, Fujita K, He WW, Jay G. Prostate-specific and androgen-dependent expression of a novel homeobox gene. J Biol Chem, 1996, 271: 31779-31782
3. Bhatia-Gaur R, Donjacour AA, Sciavolino PJ, Kim M, Desai N, Young P, Norton CR et al. Roles for Nkx3.1 in prostate development and cancer. Genes Dev, 1999, 13: 966-977
4. Abdulkadir SA, Magee JA, Peters TJ, Kaleem Z, Naughton CK, Humphrey PA, Milbrandt J. Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia. Mol Cell Biol, 2002, 22: 1495-1503
5. He WW, Sciavolino PJ, Wing J, Augustus M, Hudson P, Meissner PS, Curtis RT et al. A novel human prostate-specific, androgen-regulated homeobox gene (Nkx3.1) that maps to 8p21, a region frequently deletion in prostate cancer. Genomics, 1997, 43: 69-77
6. Prescott JL, Blok L, Tindall DJ. Isolation and androgen regulation of the human homeobox cDNA, Nkx3.1. Prostate, 1998, 35: 71-80
7. Voeller HJ, Augustus M, Madike V, Bova GS, Carter KC, Gelmann EP. Coding region of Nkx3.1, a prostate-specific homeobox gene on 8p21, is not mutated in human prostate cancers. Cancer Res, 1997, 57: 4455-4459
8. Bowen C, Bubendorf L, Voeller HJ, Slack R, Willi N, Sauter G, Gasser TC et al. Loss of Nkx3.1 expression in human prostate cancers correlates with tumor progression. Cancer Res, 2000, 60: 6111-6115
9. Sambrook J, Russell DW. Molecular Cloning Third Edition. Cold Spring