Excitotoxin-induced changes in transglutaminase during differentiation of cerebellar granule cells

Amino Acids

Volumn 26, Issue 2, 2004, Pages 197-201

  Caccamo, D ^a   Curro M ^a   Cusumano, G ^b   Crisafulli, G ^a   Ientile, R ^a,c  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF PALERMO   (Italy)

^c UNIVERSITY OF MESSINA   (Italy)

Author keywords

Apoptosis; Cerebellar granule neurons; Excitotoxicity; Glutamate; Neurodegenerative diseases; Transglutaminase

Indexed keywords

1 (4 AMINOPHENYL) 4 METHYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; DIZOCILPINE; GLUTAMATE RECEPTOR; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CEREBELLUM; CONTROLLED STUDY; DEGENERATIVE DISEASE; ENZYME ACTIVITY; GRANULE CELL; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANIMALS, NEWBORN; CELL DIFFERENTIATION; CELL SURVIVAL; CEREBELLUM; N-METHYLASPARTATE; NERVE DEGENERATION; NEURONS; NEUROTOXINS; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; TIME FACTORS; TRANSGLUTAMINASES;

EID: 1942487316     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00726-003-0007-y     Document Type: Article

References (28)

1. Ankarcrona M, Dypbukt JM, Bonfoco E, Zhivotovsky B, Orrenius S, Lipton SA, Nicotera P (1995) Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15: 961-973
2. Atlante A, Gagliardi S, Marra E, Calissano P, Passarella S (1999) Glutamate neurotoxicity in rat cerebellar granule cells involves cytochrome c release from mitochondria and mitochondrial shuttle impairment. J Neurochem 73: 237-246
3. Ayata C, Ayata G, Hara H, Matthews RT, Beal MF, Ferrante RJ, Endres M, Kim A, Christie RH, Waeber C, Huang PL, Hyman BT, Moskowitz MA (1997) Mechanisms of reduced striatal NMDA excitotoxicity in type I nitric oxide synthase knock-out mice. J Neurosci 17: 6908-6917
4. Ballestar E, Abad C, Franco L (1996) Core histones are glutaminyl substrates for tissue transglutaminase. J Biol Chem 271: 18817-18824
5. Bonfoco E, Krainc D, Ankarcrona M, Nicotera P, Lipton SA (1995) Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc Natl Acad Sci USA 92: 7162-7166
6. Budd SL, Nicholls DG (1996) Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells. J Neurochem 67: 2282-2291
7. Ciardo A, Meldolesi J (1991) Regulation of intracellular calcium in cerebellar granule neurons: effects of depolarization and of glutamatergic and cholinergic stimulation. J Neurochem 56: 184-191
8. Cooper AJL, Jeitner TM, Blass JP (2002) The role of transglutaminases in neurodegenerative diseases: overview. Neurochem Int 40: 1-5
9. Doble A (1999) The role of excitotoxicity in neurodegenerative disease: implications for therapy. Pharmacol Ther 81: 163-221
10. Fesus L (1998) Transglutaminase-catalyzed protein cross-linking in the molecular program of apoptosis and its relationship to neuronal processes. Cell Mol Neurobiol 18: 683-694
11. Ientile R, Macaione V, Teletta M, Pedale S, Torre V, Macaione S (2001) Apoptosis and necrosis occurring in excitotoxic cell death in isolated chick embryo retina. J Neurochem 79: 71-78
12. Ientile R, Caccamo D, Macaione V, Torre V, Macaione S (2002) NMDA-evoked exctotoxicity increases tissue transglutaminase in cerebellar granule cells. Neuroscience 115: 723-729
13. Larm JA, Cheung NS, Beart PM (1997) Apoptosis induced via AMPA-selective glutamate receptors in cultured murine cortical neurons. J Neurochem 69: 617-622
14. Lesort M, Tucholski J, Miller ML, Johnson GVW (2000) Tissue transglutaminase: a possible role in neurodegenerative diseases. Prog Neurobiol 61: 439-463
15. Lipton SA (1997) Treating AIDS dementia. Science 276: 1629-1630
16. Loo DT, Copani A, Pike CJ, Whittemore ER, Walencewicz AJ, Cotman CW (1993) Apoptosis is induced by beta-amyloid in cultured central nervous system neurons. Proc Natl Acad Sci USA 90: 7951-7955
17. Lorand L, Campbell-Wilkes LK, Cooperstein L (1972) A filter paper assay for transamidating enzymes using radioactive amine substrates. Anal Biochem 50: 623-631
18. Melino G, Piacentini M (1998) Tissue transglutaminase in cell death: a downstream or a multifunctional upstream effector? FEBS Lett 430: 59-63
19. Nemes Z Jr., Adany R, Balazs M, Boross P, Fesus L (1997) Identification of cytoplasmic actin as an abundant glutaminyl substrate for tissue transglutaminase in HL-60 and U937 cells undergoing apoptosis. J Biol Chem 272: 20577-20583
20. Portera-Cailliau C, Hedreen JC, Price DL, Koliatsos VE (1995) Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models. J Neurosci 15: 3775-3787
21. Resink A, Villa M, Benke D, Hidaka H, Mohler H, Balazs R (1996) Characterization of agonist-induced down-regulation of NMDA receptors in cerebellar granule cell cultures. J Neurochem 66: 369-377
22. Rumbaugh G, Vicini S (1999) Distinct synaptic and extrasynaptic NMDA receptors in developing cerebellar granule neurons. J Neurosci 19: 10603-10610
23. Schousboe A, Meier E, Drejer J, Hertz L (1989) Preparation of cultures of mouse (rat) cerebellar granule cells. In: Shahar A, DeVellis JA, Vernadakis A, Haber B (eds) A dissection and tissue culture manual for the nervous system. Alan R. Liss, New York, pp 203-206
24. Snell LD, Bhave SV, Tabakoff B, Hoffman PL (2001) Chronic ethanol exposure delays the 'developmental switch' of the NMDA receptor 2A and 2B subunits in cultured cerebellar granule neurons. J Neurochem 78: 396-405
25. Taniwaki T, Hirashima N, Becerra SP, Chader GJ, Etcheberrigaray R, Schwartz JP (1997) Pigment epithelium-derived factor protects cultured cerebellar granule cells against glutamate-induced neurotoxicity. J Neurochem 68: 26-32
26. Tenneti L, Lipton SA (2000) Involvement of activated caspase-3-like proteases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons. J Neurochem 74: 134-142
27. Tucholski J, Johnson GVW (2002) Tissue transglutaminase differentially modulates apoptosis in a stimuli-dependent manner. J Neurochem 81: 780-791
28. Xia Y, Ragan RE, Seah EE, Michaelis ML, Michaelis EK (1995) Developmental expression of N-methyl-D-aspartate (NMDA)-induced neurotoxicity, NMDA receptor function, and the NMDAR1 and glutamate-binding protein subunits in cerebellar granule cells in primary cultures. Neurochem Res 20: 617-629