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1
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0038820089
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Agonist-induced coordinated trafficking of functionally related transport proteins for water and ions in cholangiocytes
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Epub 2003, Mar 26
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Tietz PS, Marinelli RA, Chen XM, et al.: Agonist-induced coordinated trafficking of functionally related transport proteins for water and ions in cholangiocytes. J Biol Chem 2003, 30;278:20413-20419. Epub 2003, Mar 26.
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J Biol Chem
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Tietz, P.S.1
Marinelli, R.A.2
Chen, X.M.3
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2
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0037458570
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Specific inhibition of AQP1 water channels in isolated rat intrahepatic bile duct units by small interfering RNAs
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Epub 2002, Dec 04
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Splinter PL, Masyuk AI, LaRusso NF, et al.: Specific inhibition of AQP1 water channels in isolated rat intrahepatic bile duct units by small interfering RNAs. J Biol Chem. 2003, 21;278:6268-6274. Epub 2002, Dec 04. This paper demonstrates the feasibility of utilizing siRNAs to specifically reduce expression of target proteins in cholangiocytes or potentially other epithelial cells.
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J Biol Chem
, vol.21
, Issue.278
, pp. 6268-6274
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Splinter, P.L.1
Masyuk, A.I.2
LaRusso, N.F.3
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3
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0043288615
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Gastrin reverses established cholangiocyte proliferation and enhanced secretin-stimulated ductal secretion of BDL rats by activation of apoptosis through increased expression of Ca2+-dependent PKC isoforms
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Glaser S, Alvaro D, Ueno Y, et al.: Gastrin reverses established cholangiocyte proliferation and enhanced secretin-stimulated ductal secretion of BDL rats by activation of apoptosis through increased expression of Ca2+- dependent PKC isoforms. Liver Int 2003, 23:78-88.
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Liver Int
, vol.23
, pp. 78-88
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Glaser, S.1
Alvaro, D.2
Ueno, Y.3
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4
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0037370065
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Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes
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Spirli C, Fabris L, Duner E, et al.: Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes. Gastroenterology 2003, 124:737-753.
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(2003)
Gastroenterology
, vol.124
, pp. 737-753
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Spirli, C.1
Fabris, L.2
Duner, E.3
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5
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0037304208
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Taurocholate feeding prevents CCl4-induced damage of large cholangiocytes through Pl3-kinase-dependent mechanism
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Marucci L, Alpini G, Glaser SS, et al.: Taurocholate feeding prevents CCl4-induced damage of large cholangiocytes through Pl3-kinase-dependent mechanism. Am J Physiol Gastrointest Liver Physiol 2003, 284:G290-G301.
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Am J Physiol Gastrointest Liver Physiol
, vol.284
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Marucci, L.1
Alpini, G.2
Glaser, S.S.3
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6
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0038339493
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Bile acids activate EGF receptor via a TGF-alpha-dependent mechanism in human cholangiocyte cell lines
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Werneburg NW, Yoon JH, Higuchi H, et al.: Bile acids activate EGF receptor via a TGF-alpha-dependent mechanism in human cholangiocyte cell lines. Am J Physiol Gastrointest Liver Physiol 2003, 285:G31-G36.
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Am J Physiol Gastrointest Liver Physiol
, vol.285
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Werneburg, N.W.1
Yoon, J.H.2
Higuchi, H.3
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7
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0037311045
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Taurohyodeoxycholate- and tauroursodeoxycholate-induced hypercholeresis is augmented in bile duct ligated rats
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Baiocchi L, Alpini G, Glaser S: Taurohyodeoxycholate- and tauroursodeoxycholate-induced hypercholeresis is augmented in bile duct ligated rats. J Hepatol 2003, 38:136-147.
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(2003)
J Hepatol
, vol.38
, pp. 136-147
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Baiocchi, L.1
Alpini, G.2
Glaser, S.3
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8
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0037405771
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Somatostatin stimulates ductal bile absorption and inhibits ductal bile secretion in mice via SSTR2 on cholangiocytes
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Gong AY, Tietz PS, Muff MA, et al.: Somatostatin stimulates ductal bile absorption and inhibits ductal bile secretion in mice via SSTR2 on cholangiocytes. Am J Physiol Cell Physiol 2003, 284:C1205-C1214.
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Am J Physiol Cell Physiol
, vol.284
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Gong, A.Y.1
Tietz, P.S.2
Muff, M.A.3
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9
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0036889696
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Characterization of regulatory volume decrease in freshly isolated mouse cholangiocytes
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Cho WK: Characterization of regulatory volume decrease in freshly isolated mouse cholangiocytes. Am J Physiol Gastrointest Liver Physiol 2002, 283:G1320-G1327.
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(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.283
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Cho, W.K.1
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10
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0037908974
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Development and characterization of secretin-stimulated secretion of cultured rat cholangiocytes
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Epub 2003, Jan 22
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Alpini G, Phinizy JL, Glaser S, et al.: Development and characterization of secretin-stimulated secretion of cultured rat cholangiocytes. Am J Physiol Gastrointest Liver Physiol 2003, 284:G1066-G1073. Epub 2003, Jan 22. The ability to establish individual long-term cultures derived from small, medium, and large ducts would provide a valuable model to study transport and secretion phenomena.
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(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
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Alpini, G.1
Phinizy, J.L.2
Glaser, S.3
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11
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0037377693
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Hepatic artery and portal vein remodeling in rat liver: Vascular response to selective cholangiocyte proliferation
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Masyuk TV, Ritman EL, LaRusso NF: Hepatic artery and portal vein remodeling in rat liver: vascular response to selective cholangiocyte proliferation. Am J Pathol 2003, 162:1175-1182.
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(2003)
Am J Pathol
, vol.162
, pp. 1175-1182
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Masyuk, T.V.1
Ritman, E.L.2
LaRusso, N.F.3
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12
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25544465243
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Cholangiocytes contain primary cilia that function as sensory organelles: Potential role in ductal bile formation
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Masyuk AI, Masyuk TV, Splinter PL, et al.: Cholangiocytes contain primary cilia that function as sensory organelles: potential role in ductal bile formation. Gastroenterology 2003, 38(4 Suppl 1):208A. This work is the first report of cilia in cholangiocytes acting as sensors to effect luminal flow rates.
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(2003)
Gastroenterology
, vol.38
, Issue.4 SUPPL. 1
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Masyuk, A.I.1
Masyuk, T.V.2
Splinter, P.L.3
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13
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0141483040
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Loss of inositol 1,4,5-trisphosphate receptors from bile duct epithelia is a common event in cholestasis
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Shibao K, Hirata K, Robert ME, et al.: Loss of inositol 1,4,5-trisphosphate receptors from bile duct epithelia is a common event in cholestasis. Gastroenterology 2003, 125:1175-1187. A common pathway for cholestasis may involve the loss of InsP3Rs and, as a result, affect calcium and bicarbonate secretion.
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(2003)
Gastroenterology
, vol.125
, pp. 1175-1187
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Shibao, K.1
Hirata, K.2
Robert, M.E.3
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14
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17144472251
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Dopaminergic inhibition of secretin-stimulated choleresis by increased PKC-gamma expression and decrease of PKA activity
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Epub 2002, Dec 27
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Glaser S, Alvaro D, Roskams T, et al.: Dopaminergic inhibition of secretin-stimulated choleresis by increased PKC-gamma expression and decrease of PKA activity. Am J Physiol Gastrointest Liver Physiol 2003, 284:G683-G694. Epub 2002, Dec 27.
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Am J Physiol Gastrointest Liver Physiol
, vol.284
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Glaser, S.1
Alvaro, D.2
Roskams, T.3
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15
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17644443179
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Taurocholate prevents the loss of intrahepatic bile ducts due to vagotomy in bile duct-ligated rats
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Epub 2003, Jan 29
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Marzioni M, LeSage GD, Glaser S: Taurocholate prevents the loss of intrahepatic bile ducts due to vagotomy in bile duct-ligated rats. Am J Physiol Gastrointest Liver Physiol 2003, 284:G837-G852. Epub 2003, Jan 29.
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Am J Physiol Gastrointest Liver Physiol
, vol.284
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Marzioni, M.1
LeSage, G.D.2
Glaser, S.3
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16
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0038678229
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Increased susceptibility of cholangiocytes to tumor necrosis factor-alpha cytotoxicity after bile duct ligation
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Epub 2003 Mar 12
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Alipin G, Ueno Y, Tadlock L, et al.: Increased susceptibility of cholangiocytes to tumor necrosis factor-alpha cytotoxicity after bile duct ligation. Am J Physiol Cell Physiol. 2003, 285:C183-C194. Epub 2003 Mar 12.
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Am J Physiol Cell Physiol
, vol.285
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Alipin, G.1
Ueno, Y.2
Tadlock, L.3
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17
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25544438933
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Fibrocystin, the ARPKD protein, is localized to cholangiocyte cilia and is disrupted in the orthologous rat model PCK
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Masyuk TV, Huang BQ, Masyuk AI, et al.: Fibrocystin, the ARPKD protein, is localized to cholangiocyte cilia and is disrupted in the orthologous rat model PCK. Gastroenterology 2003, 38(Suppl 14):167A.
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(2003)
Gastroenterology
, vol.38
, Issue.14 SUPPL.
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Masyuk, T.V.1
Huang, B.Q.2
Masyuk, A.I.3
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18
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0038054141
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Cryptosporidium parvum invasion of biliary epithelia requires host cell tyrosine phosphorylation of cortactin via c-Src
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Chen XM, Huang BQ, Splinter PL, et al.: Cryptosporidium parvum invasion of biliary epithelia requires host cell tyrosine phosphorylation of cortactin via c-Src. Gastroenterology 2003, 125:216-228.
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Gastroenterology
, vol.125
, pp. 216-228
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Chen, X.M.1
Huang, B.Q.2
Splinter, P.L.3
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19
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2442452473
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Cryptosporidium parvum attachment to and internalization by human biliary epithelia in vitro: A morphologic study
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in press
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Huang BQ, Chen XM, LaRusso NF, et al.: Cryptosporidium parvum attachment to and internalization by human biliary epithelia in vitro: a morphologic study. J Parasitol, in press.
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J Parasitol
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Huang, B.Q.1
Chen, X.M.2
LaRusso, N.F.3
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20
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0037572072
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Double-stranded RNA activates a p38 MARK-dependent cell survival program in biliary epithelia
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Epub 2003, Jan 22
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Tadlock L, Yamagiwa Y, Marienfeld C, et al.: Double-stranded RNA activates a p38 MARK-dependent cell survival program in biliary epithelia. Am J Physiol Gastrointest Liver Physiol 2003, 284:G924-G932. Epub 2003, Jan 22.
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Tadlock, L.1
Yamagiwa, Y.2
Marienfeld, C.3
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21
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0037784237
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Translational regulation by p38 mitogen-activated protein kinase signaling during human cholangiocarcinoma growth
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Yamagiwa Y, Marienfeld C, Tadlock L, et al.: Translational regulation by p38 mitogen-activated protein kinase signaling during human cholangiocarcinoma growth. Hepatology 2003, 38:158-166.
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Hepatology
, vol.38
, pp. 158-166
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Yamagiwa, Y.1
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Tadlock, L.3
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