The instantly released Drosophila immune proteome is infection-specific

Biochemical and Biophysical Research Communications

Volumn 317, Issue 4, 2004, Pages 1052-1060

  Vierstraete, Evy ^a   Verleyen, Peter ^a   Sas, Filip ^a   Van Den Bergh, Gert ^a   De Loof, Arnold ^a   Arckens, Lutgarde ^a   Schoofs, Liliane ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Drosophila melanogaster; Immune response proteins; Micrococcus luteus; Saccharomyces cerevisiae; Secretome; Two dimensional difference gel electrophoresis

Indexed keywords

DROSOPHILA PROTEIN; LIPOPOLYSACCHARIDE; PROTEOME;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; DROSOPHILA; GRAM POSITIVE BACTERIUM; HEMOLYMPH; IMMUNE RESPONSE; IMMUNE SYSTEM; LARVA; METAZOON; MICROCOCCUS LUTEUS; MYCOSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN SECRETION; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; TWO DIMENSIONAL ELECTROPHORESIS; UPREGULATION; YEAST;

ANIMALS; BACTERIAL INFECTIONS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE EXPRESSION PROFILING; HEMOLYMPH; LARVA; LIPOPOLYSACCHARIDES; MICROCOCCUS LUTEUS; MYCOSES; PROTEOME; SACCHAROMYCES CEREVISIAE;

DROSOPHILA MELANOGASTER; MELANOGASTER; METAZOA; MICROCOCCUS; MICROCOCCUS LUTEUS; POSIBACTERIA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 1942484340     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.03.150     Document Type: Article

References (38)

1. Hultmark D. Immune reactions in Drosophila and other insects: a model for innate immunity. Trends Genet. 9:1993;178-183.
2. Bulet P., Hetru C., Dimarcq J.L., Hoffmann D. Antimicrobial peptides in insects; structure and function. Dev. Comp. Immunol. 23:1999;329-344.
3. Fehlbaum P., Bulet P., Michaut L., Lagueux M., Broekaert W.F., Hetru C., Hoffmann J.A. Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides. J. Biol. Chem. 269:1994;33159-33163.
4. Levashina E.A., Ohresser S., Bulet P., Reichhart J.M., Hetru C., Hoffmann J.A. Metchnikowin, a novel immune-inducible proline-rich peptide from Drosophila with antibacterial and antifungal properties. Eur. J. Biochem. 233:1995;694-700.
5. Dimarcq J.L., Hoffmann D., Meister M., Bulet P., Lanot R., Reichhart J.M., Hoffmann J.A. Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin. A study in insect immunity. Eur. J. Biochem. 221:1994;201-209.
6. Asling B., Dushay M.S., Hultmark D. Identification of early genes in the Drosophila immune response by PCR-based differential display: the attacin A gene and the evolution of attacin-like proteins. Insect. Biochem. Mol. Biol. 25:1995;511-518.
7. Kylsten P., Samakovlis C., Hultmark D. The cecropin locus in Drosophila; a compact gene cluster involved in the response to infection. EMBO J. 9:1990;217-224.
8. Charlet M., Lagueux M., Reichhart J.M., Hoffmann D., Braun A., Meister M. Cloning of the gene encoding the antibacterial peptide drosocin involved in Drosophila immunity. Expression studies during the immune response. Eur. J. Biochem. 241:1996;699-706.
9. Reichhart J.M., Meister M., Dimarcq J.L., Zachary D., Hoffmann D., Ruiz C., Richards G., Hoffmann J.A. Insect immunity: developmental and inducible activity of the Drosophila diptericin promoter. EMBO J. 11:1992;1469-1477.
10. Lemaitre B., Kromer-Metzger E., Michaut L., Nicolas E., Meister M., Georgel P., Reichhart J.M., Hoffmann J.A. A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense. Proc. Natl. Acad. Sci. USA. 92:1995;9465-9469.
11. Rutschmann S., Kilinc A., Ferrandon D. Cutting edge: the toll pathway is required for resistance to Gram-positive bacterial infections in Drosophila. J. Immunol. 168:2002;1542-1546.
12. Oliver S. Guilt-by-association goes global. Nature. 403:2000;601-603.
13. Irving P., Troxler L., Heuer T.S., Belvin M., Kopczynski C., Reichhart J.M., Hoffmann J.A., Hetru C. A genome-wide analysis of immune responses in Drosophila. Proc. Natl. Acad. Sci. USA. 98:2001;15119-15124.
14. De Gregorio E., Spellman P.T., Rubin G.M., Lemaitre B. Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays. Proc. Natl. Acad. Sci. USA. 98:2001;12590-12595.
15. Vierstraete E., Cerstiaens A., Baggerman G., Van den Bergh G., De Loof A., Schoofs L. Proteomics in Drosophila melanogaster: first 2D database of larval hemolymph proteins. Biochem. Biophys. Res. Commun. 304:2003;831-838.
16. Vierstraete E., Verleyen P., Baggerman G., D'Hertog W., Van den Bergh G., Arckens L., De Loof A., Schoofs L. A proteomic approach for the analysis of instantly released wound and immune proteins in Drosophila melanogaster hemolymph. Proc. Natl. Acad. Sci. USA. 101:2004;470-475.
17. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
18. Van den Bergh G., Clerens S., Cnops L., Vandesande F., Arckens L. Fluorescent two-dimensional difference gel electrophoresis and mass spectrometry identify age-related protein expression differences for the primary visual cortex of kitten and adult cat. J. Neurochem. 85:2003;193-205.
19. Shevchenko A., Wilm M., Vorm O., Mann M. Mass spectrometric sequencing of proteins from silver-stained polyacrylamide gels. Anal. Chem. 68:1996;850-858.
20. Gharahdaghi F., Weinberg C.R., Meagher D.A., Imai B.S., Mische S.M. Mass spectrometric identification of proteins from silver-stained polyacrylamide gel: a method for the removal of silver ions to enhance sensitivity. Electrophoresis. 20:1999;601-605.
21. Zhang W., Chait B.T. ProFound - an expert system for protein identification using mass spectrometric peptide mapping information. Anal. Chem. 72:2000;2482-2489.
22. Perkins D.N., Pappin D.J., Creasy D.M., Cottrell J.S. Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis. 20:1999;3551-3567.
23. Baggerman G., Huybrechts J., Clynen E., Hens K., Harthoorn L., Van der Horst D., Poulos C., De Loof A., Schoofs L. New insights in adipokinetic hormone (AKH) precursor processing in Locusta migratoria obtained by capillary liquid chromatography-tandem mass spectrometry. Peptides. 23:2002;635-644.
24. Levy F., Bulet P., Ehret-Sabatier L. Proteomic analysis of the systemic immune response of Drosophila. Mol. Cell. Proteomics. 3:2004;156-166.
25. Lagueux M., Perrodou E., Levashina E.A., Capovilla M., Hoffmann J.A. Constitutive expression of a complement-like protein in Toll and JAK gain-of-function mutants of Drosophila. Proc. Natl. Acad. Sci. USA. 97:2000;11427-11432.
26. Levashina E.A., Moita L.F., Blandin S., Vriend G., Lagueux M., Kafatos F.C. Conserved role of a complement-like protein in phagocytosis revealed by dsRNA knockout in cultured cells of the mosquito, Anopheles gambiae. Cell. 104:2001;709-718.
27. Oduol F., Xu J., Niare O., Natarajan R., Vernick K.D. Genes identified by an expression screen of the vector mosquito Anopheles gambiae display differential molecular immune response to malaria parasites and bacteria. Proc. Natl. Acad. Sci. USA. 97:2000;11397-11402.
28. Ramet M., Manfruelli P., Pearson A., Mathey-Prevot B., Ezekowitz R.A. Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. Nature. 416:2002;644-648.
29. Yeung K.C., Seitz T., Li S., Janosch P., McFerran B., Kaiser C., Fee F., Katsanakis K.D., Rose D.W., Mischak H., Sedivy J.M., Kolch W. Suppression of Raf-1 kinase activity and MAP kinase signaling by RKIP. Nature. 401:1999;173-177.
30. Yeung K.C., Rose D.W., Dhillon A.S., Yaros D., Gustafsson M., Chatterjee D., McFerran B., Wyche J., Kolch W., Sedivy J.M. Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappa B activation. Mol. Cell. Biol. 21:2001;7207-7217.
31. Ghosh S., May M.J., Kopp E.B. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16:1998;225-260.
32. Karin M. The NF-kappa B activation pathway: its regulation and role in inflammation and cell survival. Cancer J. Sci. Am. 4:1998;S92-S99.
33. Meylaers K., Clynen E., Daloze D., De Loof A., Schoofs L. Identification of 1-lysophosphatidylethanolamine (C(16:1)) as an antimicrobial compound in the housefly, Musca domestica. Insect Biochem. Mol. Biol. 34:2004;43-49.
34. Burmester T., Antoniewski C., Lepesant J.A. Ecdysone-regulation of synthesis and processing of fat body protein 1, the larval serum protein receptor of Drosophila melanogaster. Eur. J. Biochem. 262:1999;49-55.
35. Jiang H., Kanost M.R. The clip-domain family of serine proteinases in arthropods. Insect Biochem. Mol. Biol. 30:2000;95-105.
36. Singh S.P., Coronella J.A., Benes H., Cochrane B.J., Zimniak P. Catalytic function of Drosophila melanogaster glutathione S-transferase DmGSTS1-1 (GST-2) in conjugation of lipid peroxidation end products. Eur. J. Biochem. 268:2001;2912-2923.
37. Strausberg R.L.et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. USA. 99:2002;16899-16903. (83 authors).
38. Okazaki Y.et al. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 420:2002;563-573. (136 authors).