Structural and stability effects of phosphorylation: Localized structural changes in phenylalanine hydroxylase

Protein Science

Volumn 13, Issue 5, 2004, Pages 1219-1226

  Miranda, Frederico Faria ^a,b   Thórólfsson, Matthías ^a   Teigen, Knut ^a   Sanchez Ruiz, Jose M ^c   Martínez, Aurora ^a,d  

^a UNIVERSITY OF BERGEN   (Norway)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF GRANADA   (Spain)

^d Department of Biomedicine ^*  (Norway)

Author keywords

Conformational stability; Electrostatic interactions; Molecular dynamics simulations; Phenylalanine hydroxylase; Phosphorylation; Proteolysis

Indexed keywords

ARGININE; CHYMOTRYPSIN; HISTIDINE; IRON; PHENYLALANINE; PHENYLALANINE 4 MONOOXYGENASE; PHOSPHATE; PHOSPHOSERINE;

ARTICLE; BINDING AFFINITY; CATALYSIS; CATALYST; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; DIFFERENTIAL SCANNING CALORIMETRY; ENERGY; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; FLUORESCENCE SPECTROSCOPY; IONIZATION; MATHEMATICAL COMPUTING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIMULATION;

CALORIMETRY, DIFFERENTIAL SCANNING; CATALYTIC DOMAIN; CHYMOTRYPSIN; CIRCULAR DICHROISM; ENZYME ACTIVATION; FLUORESCENCE; PHENYLALANINE HYDROXYLASE; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN DENATURATION; SUBSTRATE SPECIFICITY; TRANSITION TEMPERATURE; TRYPSIN; TRYPTOPHAN;

EID: 1942473590     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.03595904     Document Type: Article

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