Reproduction of the tundra vole (Microtus oeconomus) with dietary phytosterol supplement

Food and Chemical Toxicology

Volumn 42, Issue 6, 2004, Pages 945-951

  Nieminen, P ^a   Mustonen, A M ^a   Paivalainen P ^a   Kukkonen, J V K ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Microtus oeconomus; Reproduction; Sitosterol; Testosterone; Tundra vole

Indexed keywords

CHOLESTEROL; PHYTOSTEROL; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL HEALTH; ANIMAL TISSUE; ARTICLE; BREEDING; CHOLESTEROL BLOOD LEVEL; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENVIRONMENTAL MONITORING; ENZYME ACTIVITY; ESTROGEN ACTIVITY; FEMALE; FOOD INTAKE; LIPID ABSORPTION; LIPID BLOOD LEVEL; MALE; NONHUMAN; PROBABILITY; PROGENY; SEX DIFFERENCE; SPECIES COMPARISON; TESTOSTERONE BLOOD LEVEL; VOLE;

ADMINISTRATION, ORAL; ANIMAL FEED; ANIMALS; ARVICOLINAE; CHOLESTEROL; FEMALE; INDUSTRIAL WASTE; LIPASE; LIVER; MALE; PHYTOSTEROLS; REPRODUCTION; TESTOSTERONE;

MICROTUS; MICROTUS OECONOMUS; MURIDAE; RODENTIA;

EID: 1942469980     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2004.02.006     Document Type: Article

References (30)

1. Baker V.A., Hepburn P.A., Kennedy S.J., Jones P.A., Lea L.J., Sumpter J.P., Ashby J. Safety evaluation of phytosterol esters. Part 1. Assessment and oestrogenicity using a combination of in vivo and in vitro assays. Food and Chemical Toxicology. 37:1999;13-22.
2. Dieterich R.A., Preston D.J. The tundra vole (Microtus oeconomus) as a laboratory animal. Laboratory Animal Science. 27:1977;500-506.
3. Drexel H., Breier C., Lisch H.-J., Sailer S. Lowering plasma cholesterol with beta-sitosterol and diet. Lancet. 23:1981;1157.
4. Hallikainen M.A., Sarkkinen E.S., Gylling H., Erkkilä A.T., Uusitupa M.I.J. Comparison of the effects of plant sterol ester and plant stanol ester-enriched margarines in lowering serum cholesterol concentrations in hypercholesterolaemic subjects on a low-fat diet. European Journal of Clinical Nutrition. 54:2000;715-725.
5. Hardie L., Trayhurn P., Abramovich D., Fowler P. Circulating leptin in women. a longitudinal study in the menstrual cycle and during pregnancy Clinical Endocrinology. 47:1997;101-106.
6. Heinemann T., Axtmann G., von Bergmann K. Comparison of intestinal absorption of cholesterol with different plant sterols in man. European Journal of Clinical Investigation. 23:1993;827-831.
7. Hendriks H.F., Brink E.J., Meijer G.W., Princen H.M., Ntanios F.Y. Safety of long-term consumption of plant sterol esters-enriched spread. European Journal of Clinical Nutrition. 57:2003;681-692.
8. Hers H.G., van Hoof F. Enzymes of glycogen degradation in biopsy material. Colowick S., Kaplan N.O. Methods in Enzymology. Vol. VIII. 1966;525-532 Academic Press, New York.
9. Jones P.J., Raeini-Sarjaz M., Ntanios F.Y., Vanstone C.A., Feng J.Y., Parsons W.E. Modulation of plasma lipid levels and cholesterol kinetics by phytosterol versus phytostanol esters. Journal of Lipid Research. 41:2000;697-705.
10. Khorasani A.M., Cheung A.P., Lee C.Y.G. Cholesterol inhibitory effects on human sperm-induced acrosome reaction. Journal of Andrology. 21:2000;586-594.
11. Kim J.-C., Kang B.-H., Shin C.-C., Kim Y.-B., Lee H.-S., Kim C.-Y., Han J., Kim K.-S., Chung D.-W., Chung M.-K. Subchronic toxicity of plant sterol esters administered by gavage to Sprague-Dawley rats. Food and Chemical Toxicology. 40:2003;1569-1580.
12. Kovacs T.G., Voss R.H., Megraw S.R., Martel P.H. Perspectives on Canadian field studies examining the potential of pulp and paper mill effluent to affect fish reproduction. Journal of Toxicology and Environmental Health. 51:1997;305-352.
13. Lo S., Russell J.C., Taylor A.W. Determination of glycogen in small tissue samples. Journal of Applied Physiology. 28:1970;234-236.
14. Mattson F.H., Grundy S.M., Crouse J. Optimizing the effect of plant sterols on cholesterol absorption in man. Americal Journal of Clinical Nutrition. 35:1982;697-700.
15. Mellanen P., Petänen T., Lehtimäki J., Mäkelä S., Bylynd G., Holmbom B., Mannila E., Oikari A., Santti R. Wood-derived estrogens. studies in vitro with breast cancer cell lines and in vivo in trout Toxicology and Applied Pharmacology. 136:1996;381-388.
16. Miettinen T.A., Puska P., Gylling H., Vanhanen H., Vartiainen E. Serum cholesterol lowering by sitostanol ester margarine in a mildly hypercholesterolemic random population. New England Journal of Medicine. 333:1995;1308-1312.
17. Moghadasian M.H. Pharmacological properties of plant sterols. In vivo and in vitro observations. Life Sciences. 67:2000;605-615.
18. Morrison P., Dieterich R., Preston D. Breeding and reproduction of fifteen wild rodents maintained as laboratory colonies. Laboratory Animal Science. 26:1976;237-243.
19. Mustonen A.M., Nieminen P., Hyvärinen H. Melatonin and the wintering strategy of the tundra vole, Microtus oeconomus. Zoological Science. 19:2002;683-687.
20. Nieminen P., Mustonen A.-M., Lindström-Seppä P., Asikainen J., Mussalo-Rauhamaa H., Kukkonen J.V.K. Phytosterols act as endocrine and metabolic disruptors in the European polecat (Mustela putorius). Toxicology and Applied Pharmacology. 178:2002;22-28.
21. Nieminen P., Lindström-Seppä P., Mustonen A.-M., Mussalo-Rauhamaa H., Kukkonen J.V.K. Bisphenol A affects endocrine physiology and biotransformation enzyme activities of the field vole (Microtus agrestis). General and Comparative Endocrinology. 126:2002;183-189.
22. Nieminen P., Mustonen A.-M., Lindström-Seppä P., Kärkkäinen V., Mussalo-Rauhamaa H., Kukkonen J.V.K. Phytosterols affect endocrinology and metabolism of the field vole (Microtus agrestis). Experimental Biology and Medicine. 228:2003;188-193.
23. Seligman A.M., Nachlas M.M. Lipase. Bermayer H.U. Methoden der Enzymatischen Analyse. 1962;776-778 Verlag Chemie GmbH, Weinheim.
24. Shintani M., Ogawa Y., Ebihara K., Aizawa-Abe M., Miyanaga F., Takaya K., Hayashi T., Inoue G., Hosoda K., Kojima M., Kangawa K., Nakao K. Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 receptor pathway. Diabetes. 50:2001;227-232.
25. Tast J. The root vole, Microtus oeconomus (Pallas), as an inhabitant of seasonally flooded land. Annales Zoologici Fennici. 3:1966;127-171.
26. Tschöp M., Smiley D.L., Heiman M.L. Ghrelin induces adiposity in rodents. Nature. 407:2000;908-913.
27. Van der Kraak G.J., Munkittrick K.R., McMaster M.E., Portt C.B., Chang J.P. Exposure to bleached kraft pulp mill effluent disrupts the pituitary-gonadal axis of white sucker at multiple sites. Toxicology and Applied Pharmacology. 115:1992;224-233.
28. Vanhanen H.T., Blomquist S., Enholm C., Hyvönen M., Jauhiainen M., Torstila I., Miettinen T.A. Serum cholesterol, cholesterol precursors, and plant sterols in hypercholesterolemic subjects with different apoE phenotypes during dietary sitostanol ester treatment. Journal of Lipid Research. 34:1993;1535-1544.
29. Waalkens-Berendsen D.H., Wolterbeek A.P.M., Wijnands M.V.W., Richold M., Hepburn P.A. Safety evaluation of phytosterol esters. Part 3. Two-generation reproduction study in rats with phytosterol esters - a novel functional food. Food and Chemical Toxicology. 37:1999;683-696.
30. Whittaker M.H., Frankos V.H., Wolterbeek A.P.M., Waalkens-Berendsen D.H. Two-generation reproductive toxicity study of plant stanol esters in rats. Regulatory Toxicology and Pharmacology. 29:1999;196-204.