Safety evaluation of phytosterol esters. Part 1. Assessment of oestrogenicity using a combination of in vivo and in vitro assays

Food and Chemical Toxicology

Volumn 37, Issue 1, 1999, Pages 13-22

  Baker, V A ^a   Hepburn, P A ^a   Kennedy, S J ^a   Jones, P A ^a   Lea, L J ^a   Sumpter, J P ^b   Ashby, J ^c  

^a UNILEVER RESEARCH   (United Kingdom)

^b BRUNEL UNIVERSITY   (United Kingdom)

^c ASTRAZENECA   (United Kingdom)

Author keywords

Sitosterol; Novel food; Oestrogen receptor binding; Oestrogenicity; Phytosterols; Plant sterols; Recombinant yeast; Uterotrophic

Indexed keywords

CAMPESTEROL; COUMESTROL; ESTRADIOL; ESTROGEN RECEPTOR; PHYTOESTROGEN; PHYTOSTEROL;

ANIMAL EXPERIMENT; ARTICLE; DRUG SAFETY; ESTROGEN ACTIVITY; FEMALE; NONHUMAN; RAT; RECEPTOR BINDING; UTERUS CONTRACTILITY; YEAST;

ADMINISTRATION, ORAL; ANIMALS; BINDING, COMPETITIVE; CHOLESTEROL; COUMESTROL; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTERS; ESTRADIOL; ESTROGENS, NON-STEROIDAL; FEMALE; ORGAN SIZE; PHYTOSTEROLS; RATS; RATS, WISTAR; RECEPTORS, ESTROGEN; SACCHAROMYCES CEREVISIAE; SITOSTEROLS; STIGMASTEROL; UTERUS;

HELIANTHUS;

EID: 0032956967     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(98)00101-X     Document Type: Article

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