Inherited platelet glycoprotein polymorphisms and a risk for coronary heart disease in young central Europeans

Thrombosis Research

Volumn 90, Issue 3, 1998, Pages 117-123

  Sperr, Wolfgang R ^a,b   Huber, Kurt ^a   Roden, Michael ^c   Janisiw, Michael ^a   Lang, Thomas ^c   Graf, Senta ^a   Maurer, Gerd ^a   Mayr, Wolfgang R ^a   Panzer, Simon ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b Division of Hematology   (Austria)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Coronary artery disease; Human platelet antigens; Platelet Glycoproteins; Polymorphisms

Indexed keywords

CHOLESTEROL; GLYCOPROTEIN IB; GLYCOPROTEIN IIB; GLYCOPROTEIN IIIA; THROMBOCYTE ANTIGEN; TRIACYLGLYCEROL;

ADULT; AGED; ALLOIMMUNIZATION; ARTICLE; ATHEROSCLEROTIC PLAQUE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY RISK; DIABETES MELLITUS; EUROPE; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SMOKING; TRIACYLGLYCEROL BLOOD LEVEL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALLELES; ANTIGENS, HUMAN PLATELET; CORONARY DISEASE; DIABETES MELLITUS; DIABETIC ANGIOPATHIES; EUROPE; FEMALE; GENE FREQUENCY; HUMANS; MALE; MIDDLE AGED; PLATELET MEMBRANE GLYCOPROTEINS; POLYMORPHISM, GENETIC; RISK FACTORS; SMOKING;

EID: 0032079569     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(98)00042-5     Document Type: Article

References (31)

1. Berk B.C., Alexander R.W., Brock T.A., Gimbrone M.A. Jr., Webb R.C. Vasoconstriction. A new activity for platelet derived growth factor Science. 232:1986;87-90.
2. Baumgartner H.R., Hosang M. Platelets, platelet-derived growth factor and arteriosclerosis. Experientia. 44:1988;109-112.
3. Fitzgerald D.J., Roy L., Catella F., Fitzgerald G.A. Platelet activation in unstable coronary artery disease. N Engl J Med. 315:1986;983-989.
4. Fuster V., Badimon L., Badimon J.J., Chesebro J.H. The pathogenesis of coronary artery disease and the acute coronary syndromes. N Engl J Med. 326:1992;242-250.
5. Plow E.F., Ginsberg M.H. Cellular adhesion. GPIIb-IIIa is a prototypic adhesion receptor Prog Hemost Thromb. 9:1989;117-156.
6. Jang Y., Lincoff A.M., Plow E.F., Topol E.J. Cell adhesion molecules in coronary artery disease. J Am Coll Cardiol. 24:1994;1591-1601.
7. Phillips D.R., Charo I.F., Parise L.V., Fitzgerald L.A. The platelet membrane glycoprotein IIb-IIIa complex. Blood. 71:1988;831-843.
8. Newman P.J. Platelet GPIIb-IIIa. Molecular variations and alloantigens Thromb Haemost. 66:1991;111-118.
9. Newman P.J., Valentin N. Human platelet alloantigens. Recent findings, new perspectives Thromb Haemost. 74:1995;234-239.
10. Weiss E.J., Bray P.F., Tayback M., Schulman S.P., Kickler T.S., Becker L.C., Weiss J.L., Gerstenblith G., Goldschmidt-Clermont P.J. A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis. N Engl J Med. 334:1996;1090-1094.
11. A1/A2 polymorphism of platelet glycoprotein IIIa and risks of myocardial infarction, stroke, and venous thrombosis. Lancet. 349:1997;385-388.
12. Marian AJ, Brugada R, Kleiman NS. N Engl J Med 1996;335:1071-2. (Letter).
13. Carter AM, Ossei-Gerning N, Grant PJ. N Engl J Med 1996;335:1072-3. (Letter).
14. Goldschmidt-Clermont PJ, Bray PF. N Engl J Med 1996;335: 1073-4. (Letter).
15. Osborn SV, Hampton KK, Smilie D, Channer KS, Daly ME. Lancet 1996;348:1309-10. (Letter).
16. Holensteiner A., Walchshofer S., Adler A., Kittl E.M., Mayr W.R., Panzer S. Human platelet antigene gene frequencies in the Austrian population. Haemostasis. 25:1995;133-136.
17. Zimrin A.B., Gidwitz S., Lord S., Schwartz E., Bennett J.S., White G.C., Poncz M. The genomic organization of platelet glycoprotein IIIa. J Biol Chem. 265:1990;8590-8595.
18. Lanza F., Kieffer N., Phillips D.R., Fitzgerald L.A. Characterization of the human platelet glycoprotein IIIa gene. Comparison with the fibronectin receptor beta-subunit gene. J Biol Chem. 265:1990;18094-18103.
19. 40 polymorphism on platelet Glycoprotein IIIa is linked to the human platelet antigen 1b. Vox Sang. 67:1994;231-234.
20. Lopez J.A., Chung D.W., Fujikawa K., Hagen F.S., Papayannopoulou T., Roth G.J. Cloning of the alpha chain of human platelet glycoprotein Ib. A transmembrane protein with homology to leucine-rich alpha 2-glycoprotein Proc Natl Acad Sci USA. 84:1987;5615-5619.
21. Wenger R.H., Kieffer N., Wicki A.N., Clementson K.J. Structure of the human blood platelet membrane glycoprotein Ib alpha chain. Biochem Biophys Res Commun. 156:1988;389-395.
22. Heidenreich R., Eisman R., Surrey S., Delgrosso K., Bennett J.S., Schwartz E., Poncz M. Organization of the gene for platelet glycoprotein IIb. Biochemistry. 29:1990;1232-1244.
23. Santoso S., Kalb R., Walka M., Kiefel V., Mueller-Eckhardt C., Newman P.J. The human platelet alloantigens Br(a) and Br(b) are associated with a single amino acid polymorphism on glycoprotein Ia (integrin subunit alpha 2). J Clin Invest. 92:1993;2427-2432.
24. Kalb R., Santoso S., Unkelbach K., Kiefel V., Mueller-Eckhardt C. Localization of the Br polymorphism on 144 bp exon of the GP Ia gene and its application in platelet DNA typing. Thromb Haemost. 71:1994;651-654.
25. Simsek S., Faber N.M., Bleeker P.M., Vekke A.B.J., Huiskes E., Goldschmeding R., Von Dem Borne A.E.G.K. Determination of human platelet antigen frequencies in the Dutch population by immunophenotyping and DNA (allele-specific restriction enzyme) analyses. Blood. 81:1993;835-840.
26. Klüter H., Fehlau K., Panzer S., Kirchner H., Bein G. Rapid typing for human platelet antigen system-1, -2, -3 and -5 by PCR amplification with sequence-specific primers. Vox Sang. 71:1996;121-125.
27. Kiefel V., Kroll H., Bonnert J., Unkelbach K. Katzmann B, Nebenführer Z, Santoso S, Mueller-Eckhardt C. Platelet alloantigen frequencies in Caucasians. A serological study Transfusion Medicine. 3:1993;237-242.
28. Kekomäki S., Partanan J., Kekomäki R. Platelet alloantigens HPA-1, -2, -3, -5 and -6b in Finns. Transfusion Medicine. 5:1995;193-198.
29. Semana G., Zazoun T., Alizadeh M., Morel-Kopp C.M., Genetet B., Kaplan C. Genetic susceptibility and anti-human platelet antigen 5b alloimmunization role of HLA class II and TAP genes. Hum Immunol. 46:1996;114-119.
30. A1 antigen. Hum Immunol. 27:1990;73-79.
31. Unkelbach K., Kalb R., Santoso S., Kiefel V., Mueller-Eckhardt C. New polymorphism on platelet glycoprotein IIIa gene recognized by endonuclease Msp I. Implications for typing by allele-specific restriction analysis Transfusion. 34:1994;592-595.