Additive antinociceptive effect of the combination of diazoxide, an activator of ATP-sensitive K+ channels, and sodium nitroprusside and dibutyryl-cGMP

European Journal of Pharmacology

Volumn 489, Issue 1-2, 2004, Pages 59-65

  Alves, Daniela P ^a   Soares, Adriana C ^a   Francischi, Janetti N ^a   Castro, Maria S A ^a   Perez, Andréa C ^a   Duarte, Igor D G ^a  

^a Institute of Biological Sciences   (Brazil)

Author keywords

Antinociception; db cGMP; Diazoxide; K+ channel opener; Sodium nitroprusside

Indexed keywords

1 (2 HYDROXY 5 TRIFLUOROMETHYLPHENYL) 5 TRIFLUOROMETHYL 2(3H) BENZIMIDAZOLONE; ADENOSINE TRIPHOSPHATE; CALCIUM ACTIVATED POTASSIUM CHANNEL; CHARYBDOTOXIN; DEQUALINIUM; DIAZOXIDE; DIBUTYRYL CYCLIC GMP; GLIBENCLAMIDE; GUANYLATE CYCLASE; METHYLENE BLUE; NALOXONE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; OPIATE ANTAGONIST; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; PROSTAGLANDIN E2; TETRYLAMMONIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG ADMINISTRATION ROUTE; DRUG EFFECT; DRUG MECHANISM; DRUG SPECIFICITY; ENZYME INACTIVATION; ENZYME INHIBITION; EXPERIMENT; HINDLIMB; HYPERALGESIA; INJECTION; LOW DRUG DOSE; MALE; NONHUMAN; PRESSURE; PRIORITY JOURNAL; RAT;

ANALGESICS; ANIMALS; BENZIMIDAZOLES; DIAZOXIDE; DIBUTYRYL CYCLIC GMP; DINOPROSTONE; DRUG SYNERGISM; ENDORPHINS; HYPERALGESIA; KINETICS; MALE; MEMBRANE PROTEINS; NALOXONE; NARCOTIC ANTAGONISTS; NITRIC OXIDE; NITROPRUSSIDE; PAIN MEASUREMENT; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; RATS; RATS, WISTAR;

EID: 1942451899     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.02.022     Document Type: Article

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