Cromakalim differentially enhances antinociception induced by agonists of alpha2 adrenoceptors, γ-aminobutyric acidB, Mu and Kappa opioid receptors

Journal of Pharmacology and Experimental Therapeutics

Volumn 276, Issue 3, 1996, Pages 1136-1142

  Ocaña, María ^a   Barrios, Manuel ^a   Baeyens, José M ^a  

^a UNIVERSITY OF GRANADA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0030111372     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (61)

1. 2 and opiate effector mechanisms in the locus coeruleus: Intracellular studies in brain slices. Neuropharmacology 26: 793-799, 1987.
2. + channels. Science 247: 852-854, 1990.
3. ARONSON, J. K.: Potassium channels m nervous tissue. Biochem. Pharmacol. 43: 11-14, 1992.
4. ASHCROFT, F. M.: Adenosine 5′-triphosphate-sensitive potassium channels. Annu. Rev. Neurosci. 11: 97-118, 1988.
5. 2- influx in rat spinal cord-dorsal root ganglion cocultures. Involvement of a GTP-binding protein J Biol. Chem 264: 347-353, 1989
6. 2-adrenoceptors and imidazoline-binding sites in the control of insulin secretion Clin. Sci. 85: 671-677, 1993.
7. CHERUBINI, E AND NORTH, R. A.: μ. and κ opioids inhibit transmitter release by different mechanisms. Proc Natl. Acad. Sci, U.S.A. 82: 1860-1863, 1985.
8. 1 opiate binding sites. Neuropharmacology 27: 331-332, 1988.
9. COOK, N. S. AND QUAST, U.: Potassium channel pharmacology. In Potassium Channels: Structure, Classification, Function and Therapeutic Potential, ed. by N. S. Cook, pp. 181-255, Ellis Horwood Limited, Chichester, 1990.
10. + on the responses to levcromakalim and P1060 in the isolated human myometrium. Eur. J. Pharmacol. 272: 293-296, 1995.
11. DEL POZO, E., BARRIOS, M. AND BAEYENS, J. M.: Effects of potassium channel openers on pentylenetetrazole-induced seizures in mice. Pharmacol. Toxicol 67: 182-184, 1990.
12. EDWARDS G. AND WESTON, A. H.: The pharmacology of ATP-sensitive potassium channels. Annu. Rev. Pharmacol. Toxicol. 33: 597-637, 1993.
13. 2-adrenoceptors in the ventrolateral medulla Eur. J. Pharmacol. 134: 1-13, 1987.
14. + channels by GABA. Trends Neurosci. 15: 46-51, 1992.
15. + channel openers prevent epilepsy induced by the bee venom peptide MCD. Eur. J. Pharmacol. 159: 329-330, 1989.
16. HALEY, T. J. AND MCCORMICK, W. G.: Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse. Br. J Pharmacol. 12: 12-15, 1957.
17. + channels in the central nervous system. In Potassium Channels: Structure, Classification, Function and Therapeutic Potential, ed. by N. S. Cook, pp. 348-381, Ellis Horwood Limited, Chichester, 1990.
18. + conductance in guinea-pig hippocampal pyramidal cells maintained in vitro. Br. J. Pharmacol. 84: 833-841, 1985.
19. 1 receptors by G proteins in rat ventricular myocytes. Am. J. Physiol. 259: H820-H826, 1990.
20. 2 receptors in rat substantia nigra neurones J. Physiol. 401: 437-453, 1988.
21. LONGMAN, S. D. AND HAMILTON, T. C.: Potassium channel activator drugs: Mechanism of action, pharmacological properties, and therapeutic potential. Med. Res. Rev. 12: 73-148, 1992
22. 3H]RX821002 (2-methoxy idazoxan) in the human and rat brains. J. Pharmacol. Exp. Ther. 264: 1187-1197, 1993.
23. MIYAKE, M., MACDONALD, J. C. AND NORTH, R. A.: Single potassium channels opened by opioids in rat locus ceruleus neurons. Proc. Natl Acad. Sci. U.S.A. 86: 3419-3422, 1989.
24. NARITA, M., SUZUKI, T., MISAWA, M., NAGASE, H., NABECHIMA, A., ASHIZAWA, T., OZAWA, H., SAITO, T. AND TAKAHATA, N.: Role of central ATP-sensitive potassium channels in the analgesic effect and spinal noradrenaline turnoverenhancing effect of intracerebroventricularly injected morphine in mice. Brain Res. 596: 209-214, 1992.
25. NARITA, M., TAKAHASHI, Y., SUZUKI, T., MISAWA, M. AND NAGASE, H.: An ATP-sensitive potassium channel blocker abolishes the potentiating effect of morphine on the bieuculline-induced convulsions in mice. Psychopharmaeology 110: 500-502, 1993a.
26. NARITA, M., TAKAMORI, K., KAWASHIMA, N., FUNADA, M., KAMEI, J., SUZUKI, T., MISAWA, M. AND NAGASE, H.: Activation of central ATP-sensitive potassium channels produces the antinociception and spinal noradrenaline turnoverenhancing effect in mice. Psychopharmacology 113: 11-14, 1993b.
27. NORTH, R. A.: Drug receptors and the inhibition of nerve cells. Br. J. Pharmacol. 98: 13-28, 1989.
28. NORTH, R. A. AND WILLIAMS, J. T.: On the potassium conductance increased by opioids in rat locus coeruleus neurones. J. Physiol. 364: 265-280, 1985.
29. B and κ-opioid receptor agonists. Br. J. Pharmacol. 110: 1049-1054, 1993.
30. + channels in antinociception induced by R-PIA an adenosine A1 receptor agonist. NaunynSchmiedeberg's Arch. Pharmacol. 350: 57-62, 1994.
31. OCAÑA, M., DEL Pozo. E., BARRIOS, M., ROBLES, L. I. AND BAEYENS, J. M.: An ATP-dependent potassium channel blocker antagonizes morphine analgesia. Eur. J. Pharmacol. 186: 377-378, 1990.
32. + channel antagonist, antagonizes morphine-induced hypermotility. Eur. J. Pharmacol. 239: 253-255, 1993a.
33. + channel blockers antagonize morphine- but not U-50488H-induced antinociception. Eur. J. Pharmacol. 230: 203-207, 1993b.
34. + channelacting drugs. Br. J. Pharmacol. 114: 1296-1302, 1995.
35. PERTOVAARA, A.: Antinociception induced by alpha-2-adrenoceptor agonists, with special emphasis on medetomidine studies. Prog. Neurobiol. 40: 691-709, 1993.
36. + channels in cultured rat hippocampal neurons: activation by cromakalim and energy-depleting conditions. Mol. Pharmacol. 40: 308-315, 1991.
37. PORRECA, F., MOSBERG, H. I , HURST, R., HRUBY, V. J. AND BURKS, T. F.: Roles of mu, delta and kappa opioid receptors in spinal and supraspinal mediation of gastrointestinal transit effects and hot-plate analgesia in the mouse. J. Pharmacol. Exp. Ther. 230: 341-348, 1984
38. + channels. Trends Pharmacol. Sci. 10: 431-435, 1989.
39. QUAYLE, J. M., STANDEN, N. B. AND STANFIELD, P. R.: The voltage-dependent block of ATP-sensitive potassium channels of frog skeletal muscle by caesium and barium ions. J. Physiol. 405: 677-697, 1988.
40. RAFFA, R. B. ANB MARTINEZ, R. P.: The 'glibenclamide shift' of centrally acting antinociceptive agents in mice. Brain Res. 677: 277-282, 1995.
41. ROANE, D. S. AND BOYD, N. E : Reduction of food intake and morphine analgesia by central glybenclamide. Pharmacol. Biochem. Behar. 46: 205-207, 1993.
42. ROBLES, L. I., BARRIOS, M. AND BAEYENS, J. M.: Centrally administered aminoglycoside antibiotics antagonize naloxone-precipitated withdrawal in mice acutely dependent on morphine. Neurosci. Lett. 145: 189-192, 1992.
43. + channel openers inhibit morphine withdrawal. Eur. J. Pharmacol. 251: 113-116, 1994.
44. + currents in Xenopus oocytes. Eur. J. Pharmacol. 259: 223-231, 1994.
45. + channels. Drug. Dev. Res. 28: 146-422, 1993.
46. SAWYNOK, J.: GABAergic mechanisms of analgesia: An update. Pharmacol. Biochem. Behav. 26: 463-474, 1987.
47. + channels and block neurosecretion. Proc. Natl. Acad Sci. U.S.A. 87: 3489-3492, 1990.
48. + channel in neurons of substantia nigra pars reticulata. Naunyn-Schmiedeberg's Arch. Pharmacol. 348: 113-117, 1993.
49. STEVENS, D. R., GALLAGHER, J. P. AND SHINNICK-GALLAGHER, P.: Further studies on the action of baclofen on neurons of the dorsolateral septal nucleus of the rat, in vitro. Brain Res. 358: 360-363, 1985.
50. TALLARIDA, R. J. AND MURRAY, R. B.: Manual of Pharmacologic Calculations with Computer Programs, Springer-Verlag, New York, 1987.
51. + channel. Prog. Neurobiol. 41: 21-30, 1993.
52. + efflux in rat brain cortical slices. J. Pharmacol. Exp. Ther. 263: 1293-1301, 1992.
53. TRICKLEBLANK, M D., FLOCKHART, G. AND FREEDMAN, S. B.: The potassium channel activator, BRL 34915, antagonizes a behavioural response to the muscarinic receptor agonist, pilocarpine. Eur. J. Pharmacol. 151: 349-350, 1988.
54. VERGONI, A. V., SCARANO, A.: AND BERTOLINI, A.: Pinacidil potentiates morphine analgesia. Life Sci. 50: PL135-PL138, 1992.
55. VONVOIGHTLANDER, P. F., LAHTI, R. A. AND LUDENS, J, H.: U-50,488: A selective and structurally novel non-mu (kappa) opioid agonist. J. Pharmacol. Exp. Ther. 224: 7-12, 1983.
56. WELCH, S. P. AND DUNLOW, L. D.: Antinociceptive activity of intrathecally administered potassium channel openers and opioid agonists: A common mechanism of action? J. Pharmacol. Exp. Ther. 267: 390-399, 1993.
57. WILD, K. D., VANDERAH, T., MOSBERG, H. I. AND PORRECA, F.: Opioid δ receptor subtypes are associated with different potassium channels. Eur. J. Pharmacol. 193: 135-136, 1991.
58. WILLIAMS, J. T. AND NORTH, R. A.: Catecholamine inhibition of calcium action potentials in rat locus coeruleus neurones. Neuroscience 14: 103-109, 1985
59. WILLIAMS, J T., NORTH, R. A. AND TOKIMASA, T.: Inward rectification of resting and opiate-activated potassium currents in rat locus coeruleus neurons. J. Neurosci. 8: 4299-4306, 1988.
60. 45Ca into rat cortical synaptosomes by inhibiting N- but not L-type calcium channels. Neuropharmacology 29: 439-444, 1990.
61. ZIMMERMANN, M.: Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16: 109-110, 1983.