Effects of two different high doses of irradiation on antioxidant system in the liver of guinea pigs

Experimental Oncology

Volumn 26, Issue 1, 2004, Pages 71-74

  Guney, Yildiz ^a   Bukan, Neslihan ^a   Dizman, Aysen ^b   Hicsonmez, Ayse ^c   Bilgihan, Ayse ^a  

^a GAZI UNIVERSITY   (Turkey)

^b ANKARA ONCOLOGY HOSPITAL   (Turkey)

^c ANKARA UNIVERSITY   (Turkey)

Author keywords

Antioxidant enzymes; Guinea pig liver; Radiation therapy

Indexed keywords

CATALASE; FREE RADICAL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; SELENIUM; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG MEGADOSE; GAMMA IRRADIATION; GUINEA PIG; IONIZING RADIATION; LIVER; NONHUMAN; RADIATION ABSORPTION; RADIATION DOSE; STATISTICAL SIGNIFICANCE; ENZYME ACTIVITY; IRRADIATION;

ANIMALS; ANTIOXIDANTS; CATALASE; DOSE-RESPONSE RELATIONSHIP, RADIATION; GAMMA RAYS; GLUTATHIONE PEROXIDASE; GUINEA PIGS; LIVER; OXIDATIVE STRESS; RADIATION DOSAGE; SELENIUM; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES; WHOLE-BODY IRRADIATION;

EID: 1942441635     PISSN: 02043564     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Sadani GR, Nadkarni GD. Changes in lipid peroxide levels and the activity of reactive oxygen scavenging systems in thyroid tissue after exposure to radioactive iodine in rats. Thyroid 1997; 7: 937-41.
2. Ho YS, Magnenat JL, Gargano M, Cao J. The nature of antioxidant defense mechanisms: a lesson from transgenic studies. Environ Health Persp 1998; 106: 1219-28.
3. Timothy RR, Sharma HM. Free radicals in health and disease. Indian J Clin Pract 1991; 2: 15-25.
4. Halliwell B, Gutteridge JM. Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol 1990; 186: 1-85.
5. Galeotti T, Masotti L, Borrello S, Casali E. Oxyradical metabolism and control of tumor growth. Xenobiotica 1991; 21: 1041-51.
6. Portakal O, Ozkaya, O, Erden Inal M, Bozan B, Kosan M, Sayek I. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000; 33: 279-84.
7. Sheikh FG, Pahan K, Khan M, Barbosa E, Singh I. Abnormality in catalase import into peroxisomes leads to severe neurological disorder. Proc Natl Acad Sci USA 1998; 95: 2961-6.
8. Winterbourn CC. Superoxide as an intracellular radical sink. Free Radic Biol Med 1993; 14: 85-90.
9. Mulder TP, Manni JJ, Roelofs HM, Peters WH, Wiersma A. Glutathione peroxidase in human head and neck cancer. Acta Otolaryngol 1995; 115: 331-3.
10. Sun Y, Oberley LW, Li Y. A simple method for clinical assay of superoxide dismutase. Clin Chem 1988; 34: 497-500.
11. Lowry OH. Protein measurement with the folin reagent. J Biol Chem 1951; 193: 265-75.
12. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythocyte GSH-Px. J Lab Clin Med 1967; 70: 158-69.
13. Aebi H. Catalase in vitro. Method Enzymol 1984; 105: 121-6.
14. Mihara M, Uchiyama M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Ann Biochem 1978; 86: 271-8.
15. Ellman GL. Tissue sulfhydryl groups. Arch Biochem Biophys 1959; 82: 70-7.
16. Mengubas K, Diab NA, Gokmen G, Ataman OY, Cavdar A, Cin S. Selenium status of healthy Turkish children. Biol Trace Elem Res 1996; 54: 163-72.
17. Riley PA. Free radicals in biology: oxidative stress and the effects of ionizing radiation. Int J Radiat Biol 1994; 65: 27-33.
18. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351-8.
19. Schreck R, Albermann K, Baeuerle PA. Nuclear factor kappa B: an oxidative stress-responsive transcription factor of eucaryotic cells (a review). Free Radic Res Commun 1992; 17: 221-37.
20. Zhou D, Brown SA, Yu T, Chen G, Barve S, Kang BC, Thompson JS. A high dose of ionizing radiation induces tissue-spesific activation of nuclear factor-kB in vivo. Radiat Res 1999; 151: 703-9.
21. Miura Y, Anzai K, Urano S, Ozawa T. In vivo electron paramagnetic resonance studies on oxidative stress caused by X-irradiation in whole mice. Free Radical Biol Med 1997; 23: 533-40.
22. Ueda T, Toyoshima Y, Kushihashi T, Hishida T, Yasuhara H. Effect of dimethyl sulfoxide pretreatment on activities of lipid peroxide formation, superoxide dismutase and glutathione peroxidase in the mouse liver after whole-body irradiation. J Toxicol Sci 1993; 18: 239-44.
23. Skaper SD, Fabris M, Ferrari V, Dalle Carbonare M, Leon A. Quercetin protects cutaneous tissue-associated cell types including sensory neurons from oxidative stress induced by glutathione depletion: cooperative effects of ascorbic acid. Free Radical Biol Med 1997; 22: 669-78.
24. Thresiamma KC, George J, Kuttan R. Protective effect of curcumin, ellagic acid and bixin on radiation induced toxicity. Indian J Exp Biol 1996; 34: 845-7.
25. De AK, Rajan RR, Krishnamoorthy L, Bhatt MB, Singh BB. Oxidative stress in radiation-induced interstitial pneumonitis in the rat. Int J Radiat Biol 1995; 68: 405-9.
26. Mutlu-Turkoglu U, Erbil Y, Oztezcan S, Olgac V, Toker G, Uysal M. The effect of selenium and/or vitamin E treatments on radiation-induced intestinal injury in rats. Life Sci 2000; 66: 1905-13.
27. Shimizu T, Iwanaga M, Yasunaga A, Urata Y, Goto S, Shibata S, Kondo T. Protective role of glutathione synthesis on radiation-induced DNA damage in rabbit brain. Cell Mol Neurobiol 1998; 18: 299-310.