Yogurt feeding inhibits promotion and progression of experimental colorectal cancer

Medical Science Monitor

Volumn 10, Issue 4, 2004, Pages

  De LeBlanc, Alejandra De Moreno ^a,b   Perdigón, Gabriela ^a,b  

^a UNIVERSIDAD NACIONAL DE TUCUMÁN   (Argentina)

^b CENTRO DE REFERENCIA PARA LACTOBACILOS CERELA CONICET   (Argentina)

Author keywords

Colon cancer; Immune response; Yogurt

Indexed keywords

1,2 DIMETHYLHYDRAZINE; CARCINOGEN; CD4 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 4; TUMOR NECROSIS FACTOR ALPHA; YOGHURT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CLASSIFICATION; CANCER GROWTH; CANCER STAGING; COLON BIOPSY; COLORECTAL CANCER; CONTROLLED STUDY; DIET SUPPLEMENTATION; DISEASE MODEL; HISTOLOGY; INHIBITION KINETICS; MOUSE; NONHUMAN;

1,2-DIMETHYLHYDRAZINE; ANIMALS; ANTIGENS, CD4; APOPTOSIS; CARCINOGENS; COLORECTAL NEOPLASMS; CYTOKINES; INTESTINES; MICE; MICE, INBRED BALB C; PEYER'S PATCHES; RECEPTORS, INTERLEUKIN-2; T-LYMPHOCYTES; YOGURT;

EID: 1942438978     PISSN: 12341010     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Fuller R: Probiotics in human medicine. Gut, 1991; 32: 439-42
2. Isolauri E, Sütas Y, Kankaanpaa P et al: Probiotics: effects on immunity. Am J Clin Nutr, 2001; 73: 444S-50S
3. Perdigon G, de Macias M E, Alvarez S et al: Systemic augmentation of the immune response in mice by feeding fermented milks with Lactobacillus casei and Lactobacillus acidophilus. Immunology, 1988; 63: 17-23
4. Meydani SN, Ha WK. Immunologic effects of yogurt. Am J Clin Nutr, 2000; 71: 861-72
5. Perdigon G, Fuller R, Raya R: Lactic acid bacteria and their effect on the immune system. Curr Issues Intest Microbiol, 2001; 2: 2742
6. Brady LJ, G Daniel D, Busta FF: The role of probiotic cultures in the prevention of colon cancer. J Nutr, 2000; 130: 410S-144S
7. Kato I: Antitumor activity of lactic acid bacteria. In: Fuller R, Predigón G, editors. Probiotics 3: Immunomodulation by the gut microflora and probiotics. Kluwer Academic Publishers London, 2000, p. 115
8. Perdigon G, Valdez JC, Rachid M: Antitumour activity of yogurt: study of possible immune mechanisms. J Dairy Res, 1998; 65: 129-38
9. Goldin BR, Gorbach SL: Effect of Lactobacillus acidophilus dietary supplements on 1, 2-dimethylhydrazine dihydrochloride-induced intestinal cancer in rats. J Natl Cancer Inst, 1980; 64: 263-65
10. Perdigon G, Medici M, Bibas ME et al: Immunomodulating effects of lactic acid bacteria on mucosal and tumoral immunity. Int J Immunotherapy, 1993; 9(1): 29-52
11. Reddy B, Rivenson A: Inhibitory effect of Bifidobacterium longum on colon, mammary, and liver carcinogenesis induced by 2-amino-3methylimidazo(4-5)quinoline, a food mutagen. Cancer Res, 1993; 53: 3914-18
12. Reddy BS: Prevention of colon cancer by pre- and probiotics: evidence from laboratory studies. Br J Nutr, 1998; 80: S219-23
13. Goldin BR, Gorbach SL: The effect of milk and lactobacillus feeding on human intestinal bacterial enzyme activity. Am J Clin Nutr, 1984; 39: 756-61
14. Perdigon G, de Moreno de LeBlanc A, Valdez JC, Rachid M: Role of yoghurt in the prevention of colon cancer. Eur J Clin Nutr, 2002; 56(Suppl 3): S65-68
15. Berg DJ, Davidson N, Kuhn R et al: Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses. J Clin Invest 1996; 98: 1010-20
16. Powrie F, Menon S, Coffman RL: Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo. Eur J Immunol, 1993; 23: 2223-29
17. Nishihori H, Tsuji H, Wang H et al: Participation of endogenously produced interferon gamma in interleukin 4-mediated tumor rejection. Hum Gene Ther, 2000; 11: 659-68
18. de Moreno de LeBlanc A, Valdéz J, Perdigón G: Regulatory effect of yoghurt on intestinal inflammatory immune response. Eur J Inflamm 2004; 2(1)
19. Sainte-Marie G: A paraffin embedding technique for studies employing immunofluorescence. J Histochem Cytochem, 1962; 10: 150-56
20. Gavrieli Y, Sherman Y, Ben-Sasson S: Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation J Cell Biol, 1992; 119: 493-501
21. Feghali CA, Wright TM: Cytokines in acute and chronic inflammation. Front Biosci, 1997; 2: d12-26
22. Belardelli F, Ferrantini M: Cytokines as a link between innate and adaptive antitumor immunity. Trends Immunol, 2002; 23: 201-8
23. Rachid MM, Gobbato NM, Valdez JC et al: Effect of yogurt on the inhibition of an intestinal carcinoma by increasing cellular apoptosis. Int J Immunopathol Pharmacol, 2002; 15: 209-16
24. Frucht DM, Fukao T, Bogdan C et al: IFN-gamma production by antigen-presenting cells: mechanisms emerge. Trends Immunol, 2001; 22: 556-60
25. Read S, Powrie F: CD4(+) regulatory T cells. Curr Opin Immunol, 2001; 13: 644-49
26. Curotto de Lafaille MA, Lafaille JJ: CD4+ regulatory T cells in autoimmunity and allergy. Curr Opin Immunol, 2002; 14: 771-78
27. Sellers WR, Fisher DE: Apoptosis and cancer drug targeting. J Clin Invest, 1999; 104: 1655-61