Comparative genomic hybridization reveals a recurrent pattern of chromosomal aberrations in severe dysplasia/carcinoma in situ of the cervix and in advanced-stage cervical carcinoma

Genes Chromosomes and Cancer

Volumn 24, Issue 2, 1999, Pages 144-150

  Kirchhoff, Maria ^a   Rose, Hanne ^a   Petersen, Bodil Laub ^a   Maahr, Jan ^a   Gerdes, Tommy ^a   Lundsteen, Claes ^a   Bryndorf, Thue ^a   Kryger Baggesen, Niels ^a   Christensen, Lise ^a   Engelholm, Svend Aage ^b   Philip, John ^a  

^a University of Copenhagen   (Denmark)

^b FINSEN LABORATORY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 11Q; CHROMOSOME 13Q; CHROMOSOME 15Q; CHROMOSOME 1Q; CHROMOSOME 3P; CHROMOSOME 3Q; CHROMOSOME 4P; CHROMOSOME 5P; CHROMOSOME 6Q; CHROMOSOME 8Q; CHROMOSOME ABERRATION; CHROMOSOME MAP; CHROMOSOME XQ; COMPARATIVE GENOMIC HYBRIDIZATION; DYSPLASIA; FEMALE; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; PRIORITY JOURNAL; UTERINE CERVIX CARCINOMA; UTERINE CERVIX CARCINOMA IN SITU;

CARCINOMA IN SITU; CARCINOMA, SQUAMOUS CELL; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN; FEMALE; HUMANS; NEOPLASM RECURRENCE, LOCAL; NUCLEIC ACID HYBRIDIZATION; UTERINE CERVICAL DYSPLASIA; UTERINE CERVICAL NEOPLASMS;

EID: 0032933704     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(199902)24:2<144::AID-GCC7>3.0.CO;2-9     Document Type: Article

References (19)

1. Arnold N, Hägele L, Walz L, Schempp L, Pfisterer J, Bauknecht T, Kiechle M. 1996. Over representation of 3q and 8q material and loss of 18q material are recurrent findings in advanced human ovarian cancer. Genes Chromosomes Cancer 16:46-54.
2. Atkin Niels B, Baker MC, Fox MF. 1990. Chromosome changes in 43 carcinomas of the cervix uteri. Cancer Genet Cytogenet 44:229-241.
3. Bryndorf T, Kirchhoff M, Rose Hanne, Maahr J, Gerdes T, Karhu R, kallioniemi A, Christensen B, Lundsteen C, Philip J. 1995. Comparative genomic hybridization in clinical cytogenetics. Am J Hum Genet 57:1211-1220.
4. Brzoska PM, Levin NA, Fu KK, Kaplan MJ, Singer MI, Gray JW, Christman MF. 1995. Frequent novel DNA copy number increase in squamous cell head and neck tumors. Cancer Res 55:3055-3059.
5. du Manoir S, Speicher MR, Joos S, Schröck E, Popp S, Döhner H, Kovacs G, Robert-Nicoud M, Lichter P, Cremer T. 1993. Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization. Hum Gener 90:590-610.
6. Hampton GM, Penny LA, Baergen RN, Larson A, Brewer C, Liao S, Busby-Earle RMC, Williams AWR, Steel CM, Bird CC, Stanbridge EJ, Evans GA. 1994. Loss of heterozygosity in cervical carcinoma: Subchromosomal localization of a putative tumor-suppressor gene to chromosome 11q22-q24. Proc Natl Acad Sci USA 91:6953-6957.
7. Heselmeyer K, Schröck E, Du Manoir S, Blegen H, Shah K, Steinbeck R, Auer G, Ried T. 1996. Gain of chromosome 3q defines the transition from severe dysplasia to invasive carcinoma of the uterine cervix. Proc Natl Acad Sci USA 93:479-448.
8. Heselmeyer K, Macville M, Schröck E, Blegen H, Hellström A-C, Shah K, Auer G, Ried T. 1997. Advanced-stage cervical carcinomas are defined by a recurrent pattern of chromosomal aberrations revealing high genetic instability and a consistent gain of chromosome arm 3q. Genes Chromosomes Cancer 19:233-240.
9. International Agency for Research on Cancer (IARC). 1995. Human Papillomaviruses. Lyon: IARC.
10. Kallioniemi A, Kallioniemi OP, Sudar D, Rutovitz D, Gray JW, Waldman F, Pinkel D. 1992. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science 258:818-882.
11. Kirchhoff M, Gerdes T, Maahr J, Rose H, Lundsteen C. 1997. Automatic correction of the interfering effect of unsuppressed interspersed repetitive sequences in comparative genomic hybridization analysis. Cytometry 28:130-134.
12. Kirchhoff M, Gerdes T, Rose H, Maahr J, Ottesen AM, Lundsteen C. 1998. Detection of chromosomal gains and losses in comparative genomic hybridization analysis based on standard reference intervals. Cytometry 31:163-173.
13. Popescu NC, Dipaolo JA. 1992. Cytogenetics of cervical neoplasia. Cancer Genet Cytogenet 60:214-215.
14. Rubin SC, Hoskins WJ. 1996. Cervical cancer and preinvasive neoplasia. New York: Lippincott-Raven.
15. Soder AI, Hoare SF, Muir S, Going JJ, Parkinson EK, Keith WN. 1997. Amplification, increased dosage and in situ expression of the telomerase RNA gene in human cancer. Oncogene 14:1013-1021.
16. Solinas-Toldo S, Dürst M, Lichter P. 1997. Specific chromosomal imbalances in human papillomavirus transfected cells during progression toward immortality. Proc Natl Acad Sci USA 94:3854-3859.
17. Sonoda G, Palazzo J, du Manoir S, Godwin A, Feder M, Yakushiji, Testa JR. 1997. Comparative genomic hybridization detects frequent overrepresentation of chromosomal material from 3q26, 8q24 and 20q13 in human ovarian carcinomas. Genes Chromosomes Cancer 20:320-328.
18. Speicher MR, Howe C, Crotty P, du Manoir S, Costa J, Ward DC. 1995. Comparative genomic hybridization detects novel deletions and amplifications in head and neck squamous cell carcinomas. Cancer Res 55:1010-1013.
19. Srivatsan ES, Misra BC, Venugopalan M, Wilczynski SP. 1991. Loss of heterozygosity for alleles on chromosome 11 in cervical carcinoma. Am J Hum Genet 49:868-877.