Effect of grapefruit pulp on the pharmacokinetics of the dihydropyridine calcium antagonists nifedipine and nisoldipine

Yakugaku Zasshi

Volumn 122, Issue 5, 2002, Pages 323-329

  Ohtani, Michiteru ^a   Kawabata, Shizu ^a   Kariya, Satoru ^a   Uchino, Katsuyoshi ^a   Itou, Kei ^a   Kotaki, Hajime ^b   Kasuyama, Kunio ^c   Morikawa, Aki ^c   Seo, Isao ^d   Nishida, Noriko ^d  

^a Tokyo Postal Services Agency Hospital   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c Japan Medical Clinical Research Corporation   (Japan)

^d Ibaraki Environment Technical Center   (Japan)

Author keywords

Grapefruit; Interaction; Nifedipine; Nisoldipine; Pharmacokinetics

Indexed keywords

CALCIUM ANTAGONIST; DRUG METABOLITE; NIFEDIPINE; NISOLDIPINE; AURANTIIN; CALCIUM CHANNEL BLOCKING AGENT; FLAVANONE DERIVATIVE; FLAVONOID;

AREA UNDER THE CURVE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG METABOLISM; FOOD DRUG INTERACTION; FOOD INTAKE; GRAPEFRUIT; GRAPEFRUIT JUICE; HUMAN; JAPAN; METHODOLOGY; NORMAL HUMAN; STATISTICAL SIGNIFICANCE; ADULT; CHEMISTRY; CITRUS FRUIT; MALE;

ADULT; CALCIUM CHANNEL BLOCKERS; CITRUS; FLAVANONES; FLAVONOIDS; FOOD-DRUG INTERACTIONS; HUMANS; MALE; NIFEDIPINE; NISOLDIPINE;

EID: 19044362794     PISSN: 00316903     EISSN: 13475231     Source Type: Journal    
DOI: 10.1248/yakushi.122.323     Document Type: Article

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