메뉴 건너뛰기




Volumn 25, Issue 6, 2005, Pages 730-741

Protein kinase C delta cleavage initiates an aberrant signal transduction pathway after cardiac arrest and oxygen glucose deprivation

Author keywords

Caspase 3; Cytochrome c; Global ischemia; Hippocampus; Neurodegeneration; Organotypic slice cultures

Indexed keywords

CASPASE 3; CYTOCHROME C; ISOENZYME; PROTEIN KINASE C DELTA; PROTEIN KINASE C ISOZYME; UNCLASSIFIED DRUG;

EID: 18944383054     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jcbfm.9600071     Document Type: Article
Times cited : (44)

References (48)
  • 1
    • 0024706445 scopus 로고
    • Memory storage and neural systems
    • Alkon DL (1989) Memory storage and neural systems. Sci Am 261:42-50
    • (1989) Sci Am , vol.261 , pp. 42-50
    • Alkon, D.L.1
  • 2
    • 0036523088 scopus 로고    scopus 로고
    • Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl
    • Anantharam V, Kitazawa M, Wagner J, Kaul S, Kanthasamy AG (2002) Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl. J Neurosci 22:1738-51
    • (2002) J Neurosci , vol.22 , pp. 1738-1751
    • Anantharam, V.1    Kitazawa, M.2    Wagner, J.3    Kaul, S.4    Kanthasamy, A.G.5
  • 3
    • 0022259635 scopus 로고
    • The phorbol ester receptor: A phospholipid-regulated protein kinase
    • Ashendel CL (1985) The phorbol ester receptor: a phospholipid-regulated protein kinase. Biochim Biophys Acta 822:219-42
    • (1985) Biochim Biophys Acta , vol.822 , pp. 219-242
    • Ashendel, C.L.1
  • 4
    • 1642263353 scopus 로고    scopus 로고
    • Involvement of protein kinase C-delta in DNA damage-induced apoptosis
    • Basu A (2003) Involvement of protein kinase C-delta in DNA damage-induced apoptosis. J Cell Mol Med 7:341-350
    • (2003) J Cell Mol Med , vol.7 , pp. 341-350
    • Basu, A.1
  • 5
    • 0035204621 scopus 로고    scopus 로고
    • Protein kinase C isoforms as therapeutic targets in nervous system disease states
    • Battaini F (2001) Protein kinase C isoforms as therapeutic targets in nervous system disease states. Pharmacol Res 44:353-61
    • (2001) Pharmacol Res , vol.44 , pp. 353-361
    • Battaini, F.1
  • 6
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-54
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.1
  • 10
    • 0037246123 scopus 로고    scopus 로고
    • Regulation of cell apoptosis by protein kinase c delta
    • Brodie C, Blumberg PM (2003) Regulation of cell apoptosis by protein kinase c delta. Apoptosis 8:19-27
    • (2003) Apoptosis , vol.8 , pp. 19-27
    • Brodie, C.1    Blumberg, P.M.2
  • 12
    • 0033022633 scopus 로고    scopus 로고
    • Translocation of protein kinase Cepsilon and protein kinase Cdelta to membrane is required for ultraviolet B-induced activation of mitogen-activated protein kinases and apoptosis
    • Chen N, Ma W, Huang C, Dong Z (1999) Translocation of protein kinase Cepsilon and protein kinase Cdelta to membrane is required for ultraviolet B-induced activation of mitogen-activated protein kinases and apoptosis. J Biol Chem 274:15389-94
    • (1999) J Biol Chem , vol.274 , pp. 15389-15394
    • Chen, N.1    Ma, W.2    Huang, C.3    Dong, Z.4
  • 13
    • 0033602745 scopus 로고    scopus 로고
    • Changes in nuclear protein kinase C-delta holoenzyme, its catalytic fragments, and its activity in polyomavirus-transformed pyF111 rat fibroblasts while proliferating and following exposure to apoptogenic topoisomerase-II inhibitors
    • Dal Pra I, Whitfield JF, Chiarini A, Armato U (1999) Changes in nuclear protein kinase C-delta holoenzyme, its catalytic fragments, and its activity in polyomavirus-transformed pyF111 rat fibroblasts while proliferating and following exposure to apoptogenic topoisomerase-II inhibitors. Exp Cell Res 249:147-60
    • (1999) Exp Cell Res , vol.249 , pp. 147-160
    • Dal Pra, I.1    Whitfield, J.F.2    Chiarini, A.3    Armato, U.4
  • 14
    • 0035209457 scopus 로고    scopus 로고
    • Ischemic preconditioning preserves mitochondrial function after global cerebral ischemia in rat hippocampus
    • Dave KR, Saul I, Busto R, Ginsberg MD, Sick TJ, Perez-Pinzon MA (2001) Ischemic preconditioning preserves mitochondrial function after global cerebral ischemia in rat hippocampus. J Cereb Blood Flow Metab 21:1401-10
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 1401-1410
    • Dave, K.R.1    Saul, I.2    Busto, R.3    Ginsberg, M.D.4    Sick, T.J.5    Perez-Pinzon, M.A.6
  • 16
    • 0036144679 scopus 로고    scopus 로고
    • Caspase activation and disruption of mitochondrial membrane potential during UV radiation-induced apoptosis of human keratinocytes requires activation of protein kinase C
    • Denning MF, Wang Y, Tibudan S, Alkan S, Nickoloff BJ, Qin JZ (2002) Caspase activation and disruption of mitochondrial membrane potential during UV radiation-induced apoptosis of human keratinocytes requires activation of protein kinase C. Cell Death Differ 9:40-52
    • (2002) Cell Death Differ , vol.9 , pp. 40-52
    • Denning, M.F.1    Wang, Y.2    Tibudan, S.3    Alkan, S.4    Nickoloff, B.J.5    Qin, J.Z.6
  • 17
    • 0033510014 scopus 로고    scopus 로고
    • Mitochondria in neurodegeneration: Acute ischemia and chronic neurodegenerative diseases
    • Fiskum G, Murphy AN, Beal MF (1999) Mitochondria in neurodegeneration: acute ischemia and chronic neurodegenerative diseases. J Cereb Blood Flow Metab 19:351-69
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 351-369
    • Fiskum, G.1    Murphy, A.N.2    Beal, M.F.3
  • 18
    • 0036479054 scopus 로고    scopus 로고
    • Mitochondrial permeability transition in acute neurodegeneration
    • Friberg H, Wieloch T (2002) Mitochondrial permeability transition in acute neurodegeneration. Biochimie 84:241-250
    • (2002) Biochimie , vol.84 , pp. 241-250
    • Friberg, H.1    Wieloch, T.2
  • 19
    • 0033082319 scopus 로고    scopus 로고
    • Protein kinase C delta
    • Gschwendt M (1999) Protein kinase C delta. Eur J Biochem 259:555-64
    • (1999) Eur J Biochem , vol.259 , pp. 555-564
    • Gschwendt, M.1
  • 21
    • 0032522885 scopus 로고    scopus 로고
    • Serine-70 is one of the critical sites for drug-induced Bcl2 phosphorylation in cancer cells
    • Haldar S, Basu A, Croce CM (1998) Serine-70 is one of the critical sites for drug-induced Bcl2 phosphorylation in cancer cells. Cancer Res 58:1609-15
    • (1998) Cancer Res , vol.58 , pp. 1609-1615
    • Haldar, S.1    Basu, A.2    Croce, C.M.3
  • 22
    • 0027322679 scopus 로고
    • Protein kinase C isoenzymes: Divergence in signal transduction?
    • Hug H, Sarre TF (1993) Protein kinase C isoenzymes: divergence in signal transduction? Biochem J 291:329-343
    • (1993) Biochem J , vol.291 , pp. 329-343
    • Hug, H.1    Sarre, T.F.2
  • 24
    • 0142200985 scopus 로고    scopus 로고
    • Role of proteolytic activation of protein kinase Cdelta in oxidative stress-induced apoptosis
    • Kanthasamy AG, Kitazawa M, Kanthasamy A, Anantharam V (2003) Role of proteolytic activation of protein kinase Cdelta in oxidative stress-induced apoptosis. Antioxid Redox Signal 5(5):609-20
    • (2003) Antioxid Redox Signal , vol.5 , Issue.5 , pp. 609-620
    • Kanthasamy, A.G.1    Kitazawa, M.2    Kanthasamy, A.3    Anantharam, V.4
  • 26
    • 0033959837 scopus 로고    scopus 로고
    • Induction of protein kinase Cdelta subspecies in neurons and microglia after transient global brain ischemia
    • Koponen S, Goldsteins G, Keinanen R, Koistinaho J (2000) Induction of protein kinase Cdelta subspecies in neurons and microglia after transient global brain ischemia. J Cereb Blood Flow Metab 20:93-102
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 93-102
    • Koponen, S.1    Goldsteins, G.2    Keinanen, R.3    Koistinaho, J.4
  • 27
    • 0033233483 scopus 로고    scopus 로고
    • Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector
    • Li L, Lorenzo PS, Bogi K, Blumberg PM, Yuspa SH (1999) Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector. Mol Cell Biol 19:8547-58
    • (1999) Mol Cell Biol , vol.19 , pp. 8547-8558
    • Li, L.1    Lorenzo, P.S.2    Bogi, K.3    Blumberg, P.M.4    Yuspa, S.H.5
  • 28
    • 0035088123 scopus 로고    scopus 로고
    • Arachidonic acid protects neonatal rat cardiac myocytes from ischaemic injury through epsilon protein kinase C
    • Mackay K, Mochly-Rosen D (2001) Arachidonic acid protects neonatal rat cardiac myocytes from ischaemic injury through epsilon protein kinase C. Cardiovasc Res 50:65-74
    • (2001) Cardiovasc Res , vol.50 , pp. 65-74
    • Mackay, K.1    Mochly-Rosen, D.2
  • 29
    • 0034698182 scopus 로고    scopus 로고
    • Mitochondrial translocation of protein kinase C delta in phorbol ester-induced cytochrome c release and apoptosis
    • Majumder PK, Pandey P, Sun X, Cheng K, Datta R, Saxena S, Kharbanda S, Kufe D (2000) Mitochondrial translocation of protein kinase C delta in phorbol ester-induced cytochrome c release and apoptosis. J Biol Chem 275:21793-6
    • (2000) J Biol Chem , vol.275 , pp. 21793-21796
    • Majumder, P.K.1    Pandey, P.2    Sun, X.3    Cheng, K.4    Datta, R.5    Saxena, S.6    Kharbanda, S.7    Kufe, D.8
  • 30
    • 0032125488 scopus 로고    scopus 로고
    • Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis
    • Martin LJ, Al-Abdulla NA, Brambrink AM, Kirsch JR, Sieber FE, Portera-Cailliau C (1998) Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: a perspective on the contributions of apoptosis and necrosis. Brain Res Bull 46:281-309
    • (1998) Brain Res Bull , vol.46 , pp. 281-309
    • Martin, L.J.1    Al-Abdulla, N.A.2    Brambrink, A.M.3    Kirsch, J.R.4    Sieber, F.E.5    Portera-Cailliau, C.6
  • 31
    • 0028938152 scopus 로고
    • Localization of protein kinases by anchoring proteins: A theme in signal transduction
    • Mochly-Rosen D (1995) Localization of protein kinases by anchoring proteins: a theme in signal transduction. Science 268:247-51
    • (1995) Science , vol.268 , pp. 247-251
    • Mochly-Rosen, D.1
  • 32
    • 0033386202 scopus 로고    scopus 로고
    • Mitochondria in neurodegeneration: Bioenergetic function in cell life and death
    • Murphy AN, Fiskum G, Beal MF (1999) Mitochondria in neurodegeneration: bioenergetic function in cell life and death. J Cereb Blood Flow Metab 19:231-45
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 231-245
    • Murphy, A.N.1    Fiskum, G.2    Beal, M.F.3
  • 33
    • 0035413601 scopus 로고    scopus 로고
    • Protein kinase C: Structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions
    • Newton AC (2001) Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions. Chem Rev 101:2353-64
    • (2001) Chem Rev , vol.101 , pp. 2353-2364
    • Newton, A.C.1
  • 34
    • 0023764824 scopus 로고
    • The molecular heterogeneity of protein kinase C and its implications for cellular regulation
    • Nishizuka Y (1988) The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 334:661-5
    • (1988) Nature , vol.334 , pp. 661-665
    • Nishizuka, Y.1
  • 35
    • 0030758901 scopus 로고    scopus 로고
    • Presynaptic versus postsynaptic localization of mu and delta opioid receptors in dorsal and ventral striatopallidal pathways
    • Olive MF, Anton B, Micevych P, Evans CJ, Maidment NT (1997) Presynaptic versus postsynaptic localization of mu and delta opioid receptors in dorsal and ventral striatopallidal pathways. J Neurosci 17:7471-9
    • (1997) J Neurosci , vol.17 , pp. 7471-7479
    • Olive, M.F.1    Anton, B.2    Micevych, P.3    Evans, C.J.4    Maidment, N.T.5
  • 36
    • 0034688686 scopus 로고    scopus 로고
    • Co-localization of PKCepsilon with various GABA(A) receptor subunits in the mouse limbic system
    • Olive MF, Hodge CW (2000) Co-localization of PKCepsilon with various GABA(A) receptor subunits in the mouse limbic system. Neuroreport 11:683-7
    • (2000) Neuroreport , vol.11 , pp. 683-687
    • Olive, M.F.1    Hodge, C.W.2
  • 37
    • 0025922133 scopus 로고
    • Protein kinase C and regulation of the local competence of Xenopus ectoderm
    • Otte AP, Kramer IM, Durston AJ (1991) Protein kinase C and regulation of the local competence of Xenopus ectoderm. Science 251:570-3
    • (1991) Science , vol.251 , pp. 570-573
    • Otte, A.P.1    Kramer, I.M.2    Durston, A.J.3
  • 38
    • 0343247698 scopus 로고    scopus 로고
    • Antioxidants, mitochondrial hyperoxidation and electrical recovery after anoxia in hippocampal slices
    • Perez-Pinzon MA, Mumford PL, Rosenthal M, Sick TJ. (1997a) Antioxidants, mitochondrial hyperoxidation and electrical recovery after anoxia in hippocampal slices. Brain Res 754:163-70
    • (1997) Brain Res , vol.754 , pp. 163-170
    • Perez-Pinzon, M.A.1    Mumford, P.L.2    Rosenthal, M.3    Sick, T.J.4
  • 39
    • 0343907202 scopus 로고    scopus 로고
    • Rapid preconditioning protects rats against ischemic neuronal damage after 3 but not 7 days of reperfusion following global cerebral ischemia
    • Perez-Pinzon MA, Xu GP, Dietrich WD, Rosenthal M, Sick TJ (1997b) Rapid preconditioning protects rats against ischemic neuronal damage after 3 but not 7 days of reperfusion following global cerebral ischemia. J Cereb Blood Flow Metab 17:175-82
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 175-182
    • Perez-Pinzon, M.A.1    Xu, G.P.2    Dietrich, W.D.3    Rosenthal, M.4    Sick, T.J.5
  • 40
    • 0345084491 scopus 로고    scopus 로고
    • Calcium influx from the extracellular space promotes NADH hyperoxidation and electrical dysfunction after anoxia in hippocampal slices
    • Perez-Pinzon MA, Mumford PL, Carranza V, Sick TJ (1998) Calcium influx from the extracellular space promotes NADH hyperoxidation and electrical dysfunction after anoxia in hippocampal slices. J Cereb Blood Flow Metab 18:215-21
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 215-221
    • Perez-Pinzon, M.A.1    Mumford, P.L.2    Carranza, V.3    Sick, T.J.4
  • 41
    • 0006921621 scopus 로고    scopus 로고
    • Mechanism(s) of mitochondrial hyperoxidation after global cerebral ischemia
    • (Eke A, Delpy DT, eds), New York: Kluwer Academic/Plenum Publishers
    • Perez-Pinzon MA, Sick TJ, Rosenthal M (1999) Mechanism(s) of mitochondrial hyperoxidation after global cerebral ischemia. In: Oxygen transport to tissue XXI (Eke A, Delpy DT, eds), New York: Kluwer Academic/ Plenum Publishers, 175-80
    • (1999) Oxygen Transport to Tissue XXI , pp. 175-180
    • Perez-Pinzon, M.A.1    Sick, T.J.2    Rosenthal, M.3
  • 43
    • 0037437356 scopus 로고    scopus 로고
    • PKC is required for the induction of tolerance by ischemic and NMDA-mediated preconditioning in the organotypic hippocampal slice
    • Raval AP, Dave KR, Mochly-Rosen D, Sick TJ, Pérez-Pinzon MA (2003) PKC is required for the induction of tolerance by ischemic and NMDA-mediated preconditioning in the organotypic hippocampal slice. J Neurosci 23:384-91
    • (2003) J Neurosci , vol.23 , pp. 384-391
    • Raval, A.P.1    Dave, K.R.2    Mochly-Rosen, D.3    Sick, T.J.4    Pérez-Pinzon, M.A.5
  • 44
  • 45
    • 0031761325 scopus 로고    scopus 로고
    • Peptide modulators of protein-protein interactions in intracellular signaling
    • Souroujon MC, Mochly-Rosen D (1998) Peptide modulators of protein-protein interactions in intracellular signaling. Nat Biotechnol 16:919-24
    • (1998) Nat Biotechnol , vol.16 , pp. 919-924
    • Souroujon, M.C.1    Mochly-Rosen, D.2
  • 46
    • 0028216874 scopus 로고
    • The protein kinase C family for neuronal signaling
    • Tanaka C, Nishizuka Y (1994) The protein kinase C family for neuronal signaling. Annu Rev Neurosci 17:551-67
    • (1994) Annu Rev Neurosci , vol.17 , pp. 551-567
    • Tanaka, C.1    Nishizuka, Y.2
  • 47
    • 0033864485 scopus 로고    scopus 로고
    • Protein kinase C isoenzymes: A review of their structure, regulation and role in regulating airways smooth muscle tone and mitogenesis
    • Webb BL, Hirst SJ, Giembycz MA (2000) Protein kinase C isoenzymes: a review of their structure, regulation and role in regulating airways smooth muscle tone and mitogenesis. Br J Pharmacol 130:1433-52
    • (2000) Br J Pharmacol , vol.130 , pp. 1433-1452
    • Webb, B.L.1    Hirst, S.J.2    Giembycz, M.A.3
  • 48


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.