메뉴 건너뛰기




Volumn 32, Issue 10, 1996, Pages 1652-1660

Impact of scheduling on toxicity and clinical efficacy of doxorubicin: What do we know in the mid-nineties?

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DOXORUBICIN;

EID: 0030248579     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/0959-8049(96)00177-3     Document Type: Review
Times cited : (62)

References (129)
  • 1
    • 0001885549 scopus 로고
    • Anthracyclines
    • Chabner BA, Collins JM, eds. Philadelphia, J.B. Lippincott Company
    • 1. Myers CE, Chabner BA. Anthracyclines. In Chabner BA, Collins JM, eds. Cancer Chemotherapy, Principles and Practice. Philadelphia, J.B. Lippincott Company, 1990, 356-381.
    • (1990) Cancer Chemotherapy, Principles and Practice , pp. 356-381
    • Myers, C.E.1    Chabner, B.A.2
  • 3
    • 0015849162 scopus 로고
    • A clinicopathological analysis of adriamycin cardiotoxicity
    • 3. Lefrak EA, Pitha J, Rosenheim S, et al. A clinicopathological analysis of adriamycin cardiotoxicity. Cancer 1973, 32, 302-314.
    • (1973) Cancer , vol.32 , pp. 302-314
    • Lefrak, E.A.1    Pitha, J.2    Rosenheim, S.3
  • 4
    • 0018716636 scopus 로고
    • Risk factors for doxorubicin-induced congestive heart failure
    • 4. von Hoff DD, Layard MW, Basa P, et al. Risk factors for doxorubicin-induced congestive heart failure. Ann Intern Med 1979, 91, 710-717.
    • (1979) Ann Intern Med , vol.91 , pp. 710-717
    • Von Hoff, D.D.1    Layard, M.W.2    Basa, P.3
  • 5
    • 0025051505 scopus 로고
    • Doxorubicin cardiotoxicity: Analysis of prevailing hypotheses
    • 5. Olson RD, Mushlin PS. Doxorubicin cardiotoxicity: analysis of prevailing hypotheses. FASEB J 1990, 4, 3076-3086.
    • (1990) FASEB J , vol.4 , pp. 3076-3086
    • Olson, R.D.1    Mushlin, P.S.2
  • 6
    • 0019817511 scopus 로고
    • Mechanism of adriamycin cardiotoxicity: Evidence for oxidative stress
    • 6. Olson RD, Boerth RC, Gerber JG, Nies AS. Mechanism of adriamycin cardiotoxicity: evidence for oxidative stress. Life Sci 1981, 29, 1393-1401.
    • (1981) Life Sci , vol.29 , pp. 1393-1401
    • Olson, R.D.1    Boerth, R.C.2    Gerber, J.G.3    Nies, A.S.4
  • 7
    • 0027343763 scopus 로고
    • Strategies for prevention of anthracycline cardiotoxicity
    • 7. Basser RL, Green MD. Strategies for prevention of anthracycline cardiotoxicity. Cancer Treat Rev 1993, 19, 57-77.
    • (1993) Cancer Treat Rev , vol.19 , pp. 57-77
    • Basser, R.L.1    Green, M.D.2
  • 9
    • 0023630851 scopus 로고
    • The major metabolite of doxorubicin is a potent inhibitor of membrane-associated ion pumps
    • 9. Boucek RJ, Olson RD, Brenner DE, Ogunbumni EM, Inui M, Fleischer S. The major metabolite of doxorubicin is a potent inhibitor of membrane-associated ion pumps. J Biol Chem 1987, 262, 15851-15856.
    • (1987) J Biol Chem , vol.262 , pp. 15851-15856
    • Boucek, R.J.1    Olson, R.D.2    Brenner, D.E.3    Ogunbumni, E.M.4    Inui, M.5    Fleischer, S.6
  • 11
    • 0027409325 scopus 로고
    • Doxorubicin and doxorubicinol pharmacokinetics and tissue concentrations following bolus injection and continuous infusion of doxorubicin in the rabbit
    • 11. Cusack BJ, Young SP, Driskell J, Olson RD. Doxorubicin and doxorubicinol pharmacokinetics and tissue concentrations following bolus injection and continuous infusion of doxorubicin in the rabbit. Cancer Chemother Pharmacol 1993, 32, 53-58.
    • (1993) Cancer Chemother Pharmacol , vol.32 , pp. 53-58
    • Cusack, B.J.1    Young, S.P.2    Driskell, J.3    Olson, R.D.4
  • 12
    • 0015987706 scopus 로고
    • Adriamycin chemotherapy: Efficacy, safety, and pharmacological basis of an intermittent single high-dosage schedule
    • 12. Benjamin RS, Wiernik PH, Bachur NR. Adriamycin chemotherapy: efficacy, safety, and pharmacological basis of an intermittent single high-dosage schedule. Cancer 1973, 33, 19-27.
    • (1973) Cancer , vol.33 , pp. 19-27
    • Benjamin, R.S.1    Wiernik, P.H.2    Bachur, N.R.3
  • 14
    • 0019748067 scopus 로고
    • Risk factors for development of daunorubicin cardiotoxicity
    • 14. von Hoff DD, Layard M. Risk factors for development of daunorubicin cardiotoxicity. Cancer Treat Rep 1981, 65 (Suppl. 4), 19-23.
    • (1981) Cancer Treat Rep , vol.65 , Issue.SUPPL. 4 , pp. 19-23
    • Von Hoff, D.D.1    Layard, M.2
  • 15
    • 0023809309 scopus 로고
    • Long term doxorubicin cardiotoxicity in childhood: Non-invasive evaluation of the contractile state and diastolic filling
    • 15. Hausdorf G, Morf G, Beron G, et al. Long term doxorubicin cardiotoxicity in childhood: non-invasive evaluation of the contractile state and diastolic filling. Br Heart J 1988, 60, 309-315.
    • (1988) Br Heart J , vol.60 , pp. 309-315
    • Hausdorf, G.1    Morf, G.2    Beron, G.3
  • 17
  • 18
    • 0025873616 scopus 로고
    • Cardiomyopathy after treatment for osteosarcoma: A contribution to cardiotoxicity of adriamycin
    • 18. Geidel S, Garn M, Grävinghoff L, et al. Cardiomyopathy after treatment for osteosarcoma: a contribution to cardiotoxicity of adriamycin. Klin Pädiatr 1991, 203, 257-261.
    • (1991) Klin Pädiatr , vol.203 , pp. 257-261
    • Geidel, S.1    Garn, M.2    Grävinghoff, L.3
  • 19
    • 0028927953 scopus 로고
    • Left ventricular diastolic function after anthracycline chemotherapy in childhood: Relation with systolic function, symptoms, and pathophysiology
    • 19. Bu'Lock FA, Mott MG, Oakhill A, Martin RP. Left ventricular diastolic function after anthracycline chemotherapy in childhood: relation with systolic function, symptoms, and pathophysiology. Br Heart J 1995, 73, 340-350.
    • (1995) Br Heart J , vol.73 , pp. 340-350
    • Bu'Lock, F.A.1    Mott, M.G.2    Oakhill, A.3    Martin, R.P.4
  • 20
    • 0029003726 scopus 로고
    • Late effects of anthracycline therapy in childhood in relation to the function of the heart at rest and under physical stress
    • 20. Lang D, Hilger F, Binswanger J, Andelfinger G, Hartmann W. Late effects of anthracycline therapy in childhood in relation to the function of the heart at rest and under physical stress. Eur J Pediatr 1995, 154, 340-345.
    • (1995) Eur J Pediatr , vol.154 , pp. 340-345
    • Lang, D.1    Hilger, F.2    Binswanger, J.3    Andelfinger, G.4    Hartmann, W.5
  • 21
    • 0021136240 scopus 로고
    • Radionuclide angiography and endomyocardial biopsy in the assessment of doxorubicin cardiotoxicity
    • 21. Druck MN, Gulenchyn KY, Evans WK, et al. Radionuclide angiography and endomyocardial biopsy in the assessment of doxorubicin cardiotoxicity. Cancer 1984, 53, 1667-1674.
    • (1984) Cancer , vol.53 , pp. 1667-1674
    • Druck, M.N.1    Gulenchyn, K.Y.2    Evans, W.K.3
  • 22
    • 0024241817 scopus 로고
    • Doppler echocardiographic assessment of left ventricular function in patients with primary lung cancer treated with doxorubicin
    • 22. Maione S, Giunta A, Tuccillo B, et al. Doppler echocardiographic assessment of left ventricular function in patients with primary lung cancer treated with doxorubicin. Tumor: 1988, 74, 725-729.
    • (1988) Tumor , vol.74 , pp. 725-729
    • Maione, S.1    Giunta, A.2    Tuccillo, B.3
  • 23
    • 0024373675 scopus 로고
    • Early detection of doxorubicin cardiotoxicity: Interest of doppler echocardiographic analysis of left ventricular filling dynamics
    • 23. Marchandise B, Schroeder E, Bosly A, et al. Early detection of doxorubicin cardiotoxicity: interest of Doppler echocardiographic analysis of left ventricular filling dynamics. Am Heart J 1989, 118, 92-98.
    • (1989) Am Heart J , vol.118 , pp. 92-98
    • Marchandise, B.1    Schroeder, E.2    Bosly, A.3
  • 24
    • 0028989408 scopus 로고
    • Female sex and higher drug dose as risk factors for late cardiotoxic effects of doxorubicin therapy for childhood cancer
    • 24. Lipshultz SE, Lipsitz SR, Mone SM, et al. Female sex and higher drug dose as risk factors for late cardiotoxic effects of doxorubicin therapy for childhood cancer. N Engl J Med 1995, 332, 1738-1743.
    • (1995) N Engl J Med , vol.332 , pp. 1738-1743
    • Lipshultz, S.E.1    Lipsitz, S.R.2    Mone, S.M.3
  • 26
    • 0000028608 scopus 로고
    • Cardiac failure more than six years post anthracyclines
    • Abstract
    • 26. Steinherz LJ, Steinherz P. Cardiac failure more than six years post anthracyclines. Am J Cardiol 1988, 62, 505 (Abstract).
    • (1988) Am J Cardiol , vol.62 , pp. 505
    • Steinherz, L.J.1    Steinherz, P.2
  • 27
    • 0025190477 scopus 로고
    • Initial congestive heart failure, six to ten years after doxorubicin chemotherapy for childhood cancer
    • 27. Goorin AM, Chauvenet AR, Perez-Atayde AR, Cruz J, McKone R, Lipshultz SE. Initial congestive heart failure, six to ten years after doxorubicin chemotherapy for childhood cancer. J Pediatr 1990, 116, 144-147.
    • (1990) J Pediatr , vol.116 , pp. 144-147
    • Goorin, A.M.1    Chauvenet, A.R.2    Perez-Atayde, A.R.3    Cruz, J.4    McKone, R.5    Lipshultz, S.E.6
  • 28
    • 0029002097 scopus 로고
    • Cardiac failure and dysrhythmias 6-19 years after anthracycline therapy: A series of 15 patients
    • 28. Steinherz LJ, Steinherz PG, Tan C. Cardiac failure and dysrhythmias 6-19 years after anthracycline therapy: a series of 15 patients. Med Pediat Oncol 1995, 24, 352-361.
    • (1995) Med Pediat Oncol , vol.24 , pp. 352-361
    • Steinherz, L.J.1    Steinherz, P.G.2    Tan, C.3
  • 29
    • 0026557788 scopus 로고
    • Guidelines for cardiac monitoring of children during and after anthracycline therapy: Report of the cardiology committee of the children's cancer study group
    • 29. Steinherz LJ, Graham T, Hurwitz R, et al. Guidelines for cardiac monitoring of children during and after anthracycline therapy: report of the Cardiology Committee of the Children's Cancer Study Group. Pediatrics 1992, 89, 942-949.
    • (1992) Pediatrics , vol.89 , pp. 942-949
    • Steinherz, L.J.1    Graham, T.2    Hurwitz, R.3
  • 30
    • 0026714331 scopus 로고
    • The anthracyclines: Will we ever find a better doxorubicin?
    • 30. Weiss RB. The anthracyclines: will we ever find a better doxorubicin? Semin Oncol 1992, 19, 670-686.
    • (1992) Semin Oncol , vol.19 , pp. 670-686
    • Weiss, R.B.1
  • 31
    • 0344309483 scopus 로고
    • ICRF-187 reduces doxorubicin-induced cardiotoxicity with no impact on response to chemotherapy
    • 31. Wexler LH, Berg S, Andrich M, et al. ICRF-187 reduces doxorubicin-induced cardiotoxicity with no impact on response to chemotherapy. Proc Annu Meet Amer Soc Clin Oncol 1993, 29, A1434.
    • (1993) Proc Annu Meet Amer Soc Clin Oncol , vol.29
    • Wexler, L.H.1    Berg, S.2    Andrich, M.3
  • 32
    • 0026585672 scopus 로고
    • ICRF-187 permits longer treatment with doxorubicin in women with breast cancer
    • 32. Speyer JL, Green MD, Zeleniuch-Jacquotte A, et al. ICRF-187 permits longer treatment with doxorubicin in women with breast cancer. J Clin Oncol 1992, 10, 117-127.
    • (1992) J Clin Oncol , vol.10 , pp. 117-127
    • Speyer, J.L.1    Green, M.D.2    Zeleniuch-Jacquotte, A.3
  • 33
    • 0021029382 scopus 로고
    • Prevention of chronic doxorubicin cardiotoxicity in beagles by liposomal encapsulation
    • 33. Herman EH, Rahman A, Ferrans VJ, Vick JA, Schein PS. Prevention of chronic doxorubicin cardiotoxicity in beagles by liposomal encapsulation. Cancer Res 1983, 43, 5427-5432.
    • (1983) Cancer Res , vol.43 , pp. 5427-5432
    • Herman, E.H.1    Rahman, A.2    Ferrans, V.J.3    Vick, J.A.4    Schein, P.S.5
  • 35
    • 0017199039 scopus 로고
    • Studies on adriamycin using a weekly regimen demonstrating its clinical effectiveness and lack of cardiac toxicity
    • 35. Weiss AJ, Metter GE, Fletcher WS, et al. Studies on adriamycin using a weekly regimen demonstrating its clinical effectiveness and lack of cardiac toxicity. Cancer Treat Rep 1976, 60, 813-822.
    • (1976) Cancer Treat Rep , vol.60 , pp. 813-822
    • Weiss, A.J.1    Metter, G.E.2    Fletcher, W.S.3
  • 36
    • 0017697257 scopus 로고
    • Experience with the use of adriamycin in combination with other anticancer agents using a weekly schedule, with particular reference to lack of cardiac toxicity
    • 36. Weiss AJ, Manthel RW. Experience with the use of adriamycin in combination with other anticancer agents using a weekly schedule, with particular reference to lack of cardiac toxicity. Cancer 1977, 40, 2046-2052.
    • (1977) Cancer , vol.40 , pp. 2046-2052
    • Weiss, A.J.1    Manthel, R.W.2
  • 37
    • 0018900529 scopus 로고
    • Adriamycin given as a weekly schedule without a loading course: Clinically effective with reduced incidence of cardiotoxicity
    • 37. Chlebowski RT, Paroly WS, Pugh RP, et al. Adriamycin given as a weekly schedule without a loading course: clinically effective with reduced incidence of cardiotoxicity. Cancer Treat Rep 1980, 64, 47-51.
    • (1980) Cancer Treat Rep , vol.64 , pp. 47-51
    • Chlebowski, R.T.1    Paroly, W.S.2    Pugh, R.P.3
  • 39
    • 0021346057 scopus 로고
    • Phase I-II study of the continuous infusion of doxorubicin in the treatment of non-small cell lung cancer
    • 39. Green MD, Speyer JS, Bottino JC, Blum RH, Wernz JC, Muggia FM. Phase I-II study of the continuous infusion of doxorubicin in the treatment of non-small cell lung cancer. Cancer Treat Rep 1984, 68, 681-682.
    • (1984) Cancer Treat Rep , vol.68 , pp. 681-682
    • Green, M.D.1    Speyer, J.S.2    Bottino, J.C.3    Blum, R.H.4    Wernz, J.C.5    Muggia, F.M.6
  • 40
    • 0025098002 scopus 로고
    • Reduced cardiotoxicity of doxorubicin by a 6-hour infusion regimen. A prospective randomized evaluation
    • 40. Shapiro J, Gotfried M, Lishner M, Ravid M. Reduced cardiotoxicity of doxorubicin by a 6-hour infusion regimen. A prospective randomized evaluation. Cancer 1990, 65, 870-873.
    • (1990) Cancer , vol.65 , pp. 870-873
    • Shapiro, J.1    Gotfried, M.2    Lishner, M.3    Ravid, M.4
  • 41
    • 0020038042 scopus 로고
    • Reduction of doxorubicin cardiotoxicity by prolonged continuous intravenous infusion
    • 41. Legha SS, Benjamin RS, Mackay B, et al. Reduction of doxorubicin cardiotoxicity by prolonged continuous intravenous infusion. Ann Intern Med 1982, 96, 133-139.
    • (1982) Ann Intern Med , vol.96 , pp. 133-139
    • Legha, S.S.1    Benjamin, R.S.2    Mackay, B.3
  • 42
    • 0024546425 scopus 로고
    • Decreased cardiac toxicity of doxorubicin administered by continuous infusion in combination chemotherapy for metastatic breast carcinoma
    • 42. Hortobagyi GN, Frye D, Buzdar AU, et al. Decreased cardiac toxicity of doxorubicin administered by continuous infusion in combination chemotherapy for metastatic breast carcinoma. Cancer 1989, 63, 37-45.
    • (1989) Cancer , vol.63 , pp. 37-45
    • Hortobagyi, G.N.1    Frye, D.2    Buzdar, A.U.3
  • 43
    • 0020957896 scopus 로고
    • Constant infusion schedule for adriamycin. A phase I-II clinical trial of a 30-day schedule by ambulatory pump delivery system
    • 43. Lokich J, Bothe T, Zipoli R, et al. Constant infusion schedule for adriamycin. A phase I-II clinical trial of a 30-day schedule by ambulatory pump delivery system. J Clin Oncol 1983, 1, 24-28.
    • (1983) J Clin Oncol , vol.1 , pp. 24-28
    • Lokich, J.1    Bothe, T.2    Zipoli, R.3
  • 44
    • 0020530090 scopus 로고
    • Clinical evaluation of long term, continuous-infusion doxorubicin
    • 44. Garnick MB, Weiss GR, Steele GD, et al. Clinical evaluation of long term, continuous-infusion doxorubicin. Cancer Treat Rep 1983, 67, 133-142.
    • (1983) Cancer Treat Rep , vol.67 , pp. 133-142
    • Garnick, M.B.1    Weiss, G.R.2    Steele, G.D.3
  • 45
    • 0011809209 scopus 로고
    • A randomized comparison of weekly (Arm I) vs. Monthly (Arm II) doxorubicin (DOX) in combination with mitomycin C (MMC) in advanced breast cancer
    • Abstract
    • 45. Jain K, Wines R, Benedetto P, et al. A randomized comparison of weekly (Arm I) Vs. monthly (Arm II) doxorubicin (DOX) in combination with mitomycin C (MMC) in advanced breast cancer. Proc Annu Meet Am Soc Clin Oncol 1983, 2, 109 (Abstract).
    • (1983) Proc Annu Meet Am Soc Clin Oncol , vol.2 , pp. 109
    • Jain, K.1    Wines, R.2    Benedetto, P.3
  • 46
    • 0021063443 scopus 로고
    • Reduced cardiotoxicity of doxorubicin delivered on a weekly schedule
    • 46. Torti FM, Bristow MR, Howes AE, et al. Reduced cardiotoxicity of doxorubicin delivered on a weekly schedule. Ann Intern Med 1983, 99, 745-749.
    • (1983) Ann Intern Med , vol.99 , pp. 745-749
    • Torti, F.M.1    Bristow, M.R.2    Howes, A.E.3
  • 47
  • 48
    • 0021355628 scopus 로고
    • Increased therapeutic index of weekly doxorubicin in the therapy of non-small cell lung cancer: A prospective, randomized study
    • 48. Valdivieso M, Burgess MA, Ewer MS, et al. Increased therapeutic index of weekly doxorubicin in the therapy of non-small cell lung cancer: a prospective, randomized study. J Clin Oncol 1984, 2, 207-214.
    • (1984) J Clin Oncol , vol.2 , pp. 207-214
    • Valdivieso, M.1    Burgess, M.A.2    Ewer, M.S.3
  • 49
    • 0024431933 scopus 로고
    • Weekly doxorubicin versus doxorubicin every 3 weeks in cyclophosphamide, doxorubicin, and cisplatin chemotherapy for non-small cell lung cancer
    • 49. Umsawadi T, Valdivieso M, Booser DJ, et al. Weekly doxorubicin versus doxorubicin every 3 weeks in cyclophosphamide, doxorubicin, and cisplatin chemotherapy for non-small cell lung cancer. Cancer 1989, 64, 1995-2000.
    • (1989) Cancer , vol.64 , pp. 1995-2000
    • Umsawadi, T.1    Valdivieso, M.2    Booser, D.J.3
  • 50
    • 0020039397 scopus 로고
    • Adriamycin therapy by continuous intravenous infusion in patients with metastatic breast cancer
    • 50. Legha SS, Benjamin RS, Mackay B, et al. Adriamycin therapy by continuous intravenous infusion in patients with metastatic breast cancer. Cancer 1982, 49, 1762-1766.
    • (1982) Cancer , vol.49 , pp. 1762-1766
    • Legha, S.S.1    Benjamin, R.S.2    Mackay, B.3
  • 51
    • 0011809616 scopus 로고
    • Continuous intravenous infusion of adriamycin: Evaluation of its efficacy and toxicity
    • 51. Legha SS, Benjamin RS, Ewer M, et al. Continuous intravenous infusion of adriamycin: evaluation of its efficacy and toxicity. Excerpta Med Int Congr Ser 1984, 629, 378-386.
    • (1984) Excerpta Med Int Congr Ser , vol.629 , pp. 378-386
    • Legha, S.S.1    Benjamin, R.S.2    Ewer, M.3
  • 52
    • 0025770430 scopus 로고
    • Phase III comparison of doxorubicin and dacarbazine given by bolus versus infusion in patients with soft tissue sarcomas: A Southwest oncology group study
    • 52. Zalupski M, Metch B, Balcerzak S, et al. Phase III comparison of doxorubicin and dacarbazine given by bolus versus infusion in patients with soft tissue sarcomas: a Southwest Oncology Group study. J Natl Cancer Inst 1991, 83, 926-932.
    • (1991) J Natl Cancer Inst , vol.83 , pp. 926-932
    • Zalupski, M.1    Metch, B.2    Balcerzak, S.3
  • 54
    • 0022616901 scopus 로고
    • Continuous-infusion doxorubicin in the treatment of primary hepatic malignancies of childhood
    • 54. Neglia JP, Woods WG. Continuous-infusion doxorubicin in the treatment of primary hepatic malignancies of childhood. Cancer Treat Rep 1986, 70, 655-657.
    • (1986) Cancer Treat Rep , vol.70 , pp. 655-657
    • Neglia, J.P.1    Woods, W.G.2
  • 56
    • 0026042237 scopus 로고
    • A prospective randomized trial of adjuvant chemotherapy with bolus versus continuous infusion of doxorubicin in patients with high-grade extremity soft tissue sarcoma and an analysis of prognostic factors
    • 56. Casper ES, Gaynor JJ, Hajdu SI, et al. A prospective randomized trial of adjuvant chemotherapy with bolus versus continuous infusion of doxorubicin in patients with high-grade extremity soft tissue sarcoma and an analysis of prognostic factors. Cancer 1991, 68, 1221-1229.
    • (1991) Cancer , vol.68 , pp. 1221-1229
    • Casper, E.S.1    Gaynor, J.J.2    Hajdu, S.I.3
  • 57
    • 0025654343 scopus 로고
    • Phase I-II constant infusion of adriamycin (doxorubicin) by ambulatory pump delivery system in heavily pretreated (including adriamycin) breast cancer patients
    • 57. Jasmin C, Gil-Delgado MA, Marino JP, Ecstein E, Descorps-Declere A, Misset JL. Phase I-II constant infusion of adriamycin (doxorubicin) by ambulatory pump delivery system in heavily pretreated (including adriamycin) breast cancer patients. Ann Oncol 1990, 1, 189-193.
    • (1990) Ann Oncol , vol.1 , pp. 189-193
    • Jasmin, C.1    Gil-Delgado, M.A.2    Marino, J.P.3    Ecstein, E.4    Descorps-Declere, A.5    Misset, J.L.6
  • 58
    • 0021984211 scopus 로고
    • Phase I trial of an implanted battery-powered, programmable drug delivery system for continuous doxorubicin administration
    • 58. Vogelzang NJ, Ruane M, DeMeester TR. Phase I trial of an implanted battery-powered, programmable drug delivery system for continuous doxorubicin administration. J Clin Oncol 1985, 3, 407-414.
    • (1985) J Clin Oncol , vol.3 , pp. 407-414
    • Vogelzang, N.J.1    Ruane, M.2    DeMeester, T.R.3
  • 59
  • 60
    • 0024013049 scopus 로고
    • Doxorubicin dauerinfusionen. Eine pilotstudie bei jugendlichen patienten
    • 60. Bode U, Schmalenbach U. Doxorubicin Dauerinfusionen. Eine Pilotstudie bei jugendlichen Patienten. Klin Pädiatr 1988, 200, 271-273.
    • (1988) Klin Pädiatr , vol.200 , pp. 271-273
    • Bode, U.1    Schmalenbach, U.2
  • 61
    • 0027501180 scopus 로고
    • Protracted drug infusions in cancer treatment: An appraisal of 5-fluorouracil, doxorubicin, and platinums
    • 61. DelaFlor-Weiss E, Uziely B, Muggia FM. Protracted drug infusions in cancer treatment: an appraisal of 5-fluorouracil, doxorubicin, and platinums. Ann Oncol 1993, 4, 723-733.
    • (1993) Ann Oncol , vol.4 , pp. 723-733
    • DelaFlor-Weiss, E.1    Uziely, B.2    Muggia, F.M.3
  • 62
    • 0028558733 scopus 로고
    • Dose optimization of anthracyclines
    • 62. de Valeriola D. Dose optimization of anthracyclines. Anticancer Res 1994, 14, 2307-2314.
    • (1994) Anticancer Res , vol.14 , pp. 2307-2314
    • De Valeriola, D.1
  • 63
    • 0024591980 scopus 로고
    • Clinical pharmacology of continuous infusion doxorubicin
    • 63. Sweatman TW, Lokich JL, Israel M. Clinical pharmacology of continuous infusion doxorubicin. Ther Drug Monit 1989, 11, 3-9.
    • (1989) Ther Drug Monit , vol.11 , pp. 3-9
    • Sweatman, T.W.1    Lokich, J.L.2    Israel, M.3
  • 64
    • 0020662550 scopus 로고
    • Evidence of possible dose-dependent doxorubicin plasma kinetics in man
    • 64. Boston RC, Phillips DR. Evidence of possible dose-dependent doxorubicin plasma kinetics in man. Cancer Treat Rep 1983, 67, 63-69.
    • (1983) Cancer Treat Rep , vol.67 , pp. 63-69
    • Boston, R.C.1    Phillips, D.R.2
  • 65
    • 0023095549 scopus 로고
    • Pharmacokinetics of doxorubicin in sarcoma patients
    • 65. Robert J, Bui NB, Vrignaud P. Pharmacokinetics of doxorubicin in sarcoma patients. Eur J Clin Pharmacol 1987, 31, 695-699.
    • (1987) Eur J Clin Pharmacol , vol.31 , pp. 695-699
    • Robert, J.1    Bui, N.B.2    Vrignaud, P.3
  • 67
    • 0023769313 scopus 로고
    • Pharmacokinetics of doxorubicin in man: Dose and schedule dependence
    • 67. Erttmann R, Erb N, Steinhoff A, Landbeck G. Pharmacokinetics of doxorubicin in man: dose and schedule dependence. J Cancer Res Clin Oncol 1988, 114, 509-513.
    • (1988) J Cancer Res Clin Oncol , vol.114 , pp. 509-513
    • Erttmann, R.1    Erb, N.2    Steinhoff, A.3    Landbeck, G.4
  • 69
    • 0024498031 scopus 로고
    • Pharmacokinetics of weekly low dose doxorubicin
    • 69. Frenay M, Milano G, Renee N, et al. Pharmacokinetics of weekly low dose doxorubicin. Eur J Cancer Clin Oncol 1989, 25, 191-195.
    • (1989) Eur J Cancer Clin Oncol , vol.25 , pp. 191-195
    • Frenay, M.1    Milano, G.2    Renee, N.3
  • 70
    • 0024343537 scopus 로고
    • Doxorubicin: Effect of different schedules on toxicity and anti-tumor efficacy
    • 70. Bielack SS, Erttmann R, Winkler K, Landbeck G. Doxorubicin: effect of different schedules on toxicity and anti-tumor efficacy. Eur J Cancer Clin Oncol 1989, 25, 873-882.
    • (1989) Eur J Cancer Clin Oncol , vol.25 , pp. 873-882
    • Bielack, S.S.1    Erttmann, R.2    Winkler, K.3    Landbeck, G.4
  • 71
    • 0023488816 scopus 로고
    • Doxorubicin distribution in human breast cancer
    • 71. Rossi C, Gasparini G, Canobbio L, et al. Doxorubicin distribution in human breast cancer. Cancer Treat Rep 1987, 71, 1221-1226.
    • (1987) Cancer Treat Rep , vol.71 , pp. 1221-1226
    • Rossi, C.1    Gasparini, G.2    Canobbio, L.3
  • 72
    • 0025816790 scopus 로고
    • Comparative pharmacokinetics of doxorubicin given by three different schedules with equal dose intensity in patients with breast cancer
    • 72. Twelves CJ, Dobbs NA, Aldhous M, Harper PG, Rubens RD, Richards MA. Comparative pharmacokinetics of doxorubicin given by three different schedules with equal dose intensity in patients with breast cancer. Cancer Chemother Pharmacol 1991, 28, 302-307.
    • (1991) Cancer Chemother Pharmacol , vol.28 , pp. 302-307
    • Twelves, C.J.1    Dobbs, N.A.2    Aldhous, M.3    Harper, P.G.4    Rubens, R.D.5    Richards, M.A.6
  • 74
    • 0023260608 scopus 로고
    • Plasma and cellular adriamycin concentrations in patients with myeloma treated with ninety-six-hour continuous infusion
    • 74. Speth PA, Linssen PCM, Holdrinet RGS, Haanen C. Plasma and cellular adriamycin concentrations in patients with myeloma treated with ninety-six-hour continuous infusion. Clin Pharmacol Ther 1987, 41, 661-665.
    • (1987) Clin Pharmacol Ther , vol.41 , pp. 661-665
    • Speth, P.A.1    Linssen, P.C.M.2    Holdrinet, R.G.S.3    Haanen, C.4
  • 75
    • 0027303695 scopus 로고
    • Cellular pharmacokinetics of doxorubicin in patients with chronic lymphocytic leukemia: Comparison of bolus administration and continuous infusion
    • 75. Muller C, Chatelut E, Gualano V, et al. Cellular pharmacokinetics of doxorubicin in patients with chronic lymphocytic leukemia: comparison of bolus administration and continuous infusion. Cancer Chemother Pharmacol 1993, 32, 379-384.
    • (1993) Cancer Chemother Pharmacol , vol.32 , pp. 379-384
    • Muller, C.1    Chatelut, E.2    Gualano, V.3
  • 76
    • 0023637346 scopus 로고
    • Infusion-rate independent cellular adriamycin concentrations and cytotoxicity to human bone marrow clonogenic cells (CFU-GM)
    • 76. Raijmakers R, Speth P, de Witte T, Linssen P, Wessels J, Haanen C. Infusion-rate independent cellular adriamycin concentrations and cytotoxicity to human bone marrow clonogenic cells (CFU-GM). Br J Cancer 1987, 56, 123-126.
    • (1987) Br J Cancer , vol.56 , pp. 123-126
    • Raijmakers, R.1    Speth, P.2    De Witte, T.3    Linssen, P.4    Wessels, J.5    Haanen, C.6
  • 77
    • 0018364056 scopus 로고
    • Augmentation of adriamycin's therapeutic index by prolonged continuous I.V. Infusion for advanced breast cancer
    • Abstract
    • 77. Legha SS, Benjamin RS, Yap HY. Augmentation of adriamycin's therapeutic index by prolonged continuous I.V. infusion for advanced breast cancer. Proc Annu Meet Am Assoc Cancer Res 1979, 20, 261 (Abstract).
    • (1979) Proc Annu Meet Am Assoc Cancer Res , vol.20 , pp. 261
    • Legha, S.S.1    Benjamin, R.S.2    Yap, H.Y.3
  • 79
    • 0024453743 scopus 로고
    • A comparative study on the antitumor effect, cardiotoxicity and nephrotoxicity of doxorubicin given as a bolus, continuous infusion or entrapped in liposomes in the lou/M Ws1 rat
    • 79. Storm G, van Hoesel QGCM, de Groot G, Kop W, Steerenberg PA, Hillen FC. A comparative study on the antitumor effect, cardiotoxicity and nephrotoxicity of doxorubicin given as a bolus, continuous infusion or entrapped in liposomes in the lou/M Ws1 rat. Cancer Chemother Pharmacol 1989, 24, 341-348.
    • (1989) Cancer Chemother Pharmacol , vol.24 , pp. 341-348
    • Storm, G.1    Van Hoesel, Q.G.C.M.2    De Groot, G.3    Kop, W.4    Steerenberg, P.A.5    Hillen, F.C.6
  • 80
    • 0021716828 scopus 로고
    • Human plasma pharmacokinetics of doxorubicin: Comparison of bolus and infusional administration
    • 80. Brenner DE, Grosh WW, Noone R, Stein R, Greco FA, Hande KR. Human plasma pharmacokinetics of doxorubicin: comparison of bolus and infusional administration. Cancer Treat Symp 1984, 3, 77-83.
    • (1984) Cancer Treat Symp , vol.3 , pp. 77-83
    • Brenner, D.E.1    Grosh, W.W.2    Noone, R.3    Stein, R.4    Greco, F.A.5    Hande, K.R.6
  • 81
    • 0024580678 scopus 로고
    • Increasing the accumulation of daunorubicin in human leukaemia cells by prolonging the infusion time
    • 81. Paul C, Tidefeld U, Liliemark J, Peterson C. Increasing the accumulation of daunorubicin in human leukaemia cells by prolonging the infusion time. Leukemia Res 1989, 13, 191-196.
    • (1989) Leukemia Res , vol.13 , pp. 191-196
    • Paul, C.1    Tidefeld, U.2    Liliemark, J.3    Peterson, C.4
  • 82
    • 0023627395 scopus 로고
    • Doxorubicin concentration time course in the myocardium after single administration to the dog
    • 82. Timour Q, Nony P, Lang J, Lakhal M, Trllet V, Faucon G. Doxorubicin concentration time course in the myocardium after single administration to the dog. Cancer Chemother Pharmacol 1987, 20, 267-269.
    • (1987) Cancer Chemother Pharmacol , vol.20 , pp. 267-269
    • Timour, Q.1    Nony, P.2    Lang, J.3    Lakhal, M.4    Trllet, V.5    Faucon, G.6
  • 83
    • 0023598130 scopus 로고
    • Continuous infusion or intravenous bolus: What is the rationale for doxorubicin administration?
    • 83. Robert J. Continuous infusion or intravenous bolus: what is the rationale for doxorubicin administration? Cancer Drug Deliv 1987, 4, 191-199.
    • (1987) Cancer Drug Deliv , vol.4 , pp. 191-199
    • Robert, J.1
  • 84
    • 0018957289 scopus 로고
    • Dependence of the cytostatic effect of adriamycin on drug concentration and exposure time in vitro
    • 84. Eichholtz-Wirth H. Dependence of the cytostatic effect of adriamycin on drug concentration and exposure time in vitro. Br J Cancer 1980, 41, 886-891.
    • (1980) Br J Cancer , vol.41 , pp. 886-891
    • Eichholtz-Wirth, H.1
  • 85
    • 0023130372 scopus 로고
    • Evaluation of a tetrazolium-based semi-automated colorimetric assay: Assessment of chemosensitivity testing
    • 85. Carmichael J, de Graff WG, Gazdar A, Minna JD, Mitchell JB. Evaluation of a tetrazolium-based semi-automated colorimetric assay: assessment of chemosensitivity testing. Cancer Res 1987, 47, 936-942.
    • (1987) Cancer Res , vol.47 , pp. 936-942
    • Carmichael, J.1    De Graff, W.G.2    Gazdar, A.3    Minna, J.D.4    Mitchell, J.B.5
  • 86
    • 0023640184 scopus 로고
    • Comparative in vitro toxicity of mitoxantrone and adriamycin in human granulocyte-macrophage progenitor cells
    • 86. Mergenthaler HG, Bruhl P, Ehninger G, Heidemann E. Comparative in vitro toxicity of mitoxantrone and adriamycin in human granulocyte-macrophage progenitor cells. Cancer Chemother Pharmacol 1987, 20, 8-12.
    • (1987) Cancer Chemother Pharmacol , vol.20 , pp. 8-12
    • Mergenthaler, H.G.1    Bruhl, P.2    Ehninger, G.3    Heidemann, E.4
  • 87
    • 0023937084 scopus 로고
    • Lethal efficacy of doxorubicin on human medullary thyroid carcinoma cells in vitro
    • 87. Yang KP, Famaan NA. Lethal efficacy of doxorubicin on human medullary thyroid carcinoma cells in vitro. Anticancer Res 1988, 8, 245-248.
    • (1988) Anticancer Res , vol.8 , pp. 245-248
    • Yang, K.P.1    Famaan, N.A.2
  • 88
    • 0020062826 scopus 로고
    • Significance of cellular pharmacokinetics for the cytotoxic effects of daunorubicin
    • 88. Andersson B, Beran M, Peterson C, Tribukait B. Significance of cellular pharmacokinetics for the cytotoxic effects of daunorubicin. Cancer Res 1982, 42, 178-183.
    • (1982) Cancer Res , vol.42 , pp. 178-183
    • Andersson, B.1    Beran, M.2    Peterson, C.3    Tribukait, B.4
  • 89
    • 0021341566 scopus 로고
    • Cellular pharmacokinetics of doxorubicin in cultured mouse sarcoma cells originating from autochtonous tumors
    • 89. Nguyen-Ngoc T, Vrignaud P, Robert J. Cellular pharmacokinetics of doxorubicin in cultured mouse sarcoma cells originating from autochtonous tumors. Oncology 1984, 41, 55-60.
    • (1984) Oncology , vol.41 , pp. 55-60
    • Nguyen-Ngoc, T.1    Vrignaud, P.2    Robert, J.3
  • 90
    • 0022658231 scopus 로고
    • Cellular pharmacology of doxorubicin in sensitive and resistant rat glioblastoma cells in culture
    • 90. Vrignaud P, Londos-Gagliardi D, Robert J. Cellular pharmacology of doxorubicin in sensitive and resistant rat glioblastoma cells in culture. Oncology 1986, 43, 60-66.
    • (1986) Oncology , vol.43 , pp. 60-66
    • Vrignaud, P.1    Londos-Gagliardi, D.2    Robert, J.3
  • 92
    • 0018768688 scopus 로고
    • Cytotoxicity of adriamycin and daunorubicin for normal and leukemia progenitor cells of man
    • 92. Buick RN, Messner HA, Till JE, McCulloch EA. Cytotoxicity of adriamycin and daunorubicin for normal and leukemia progenitor cells of man. J Natl Cancer Inst 1979, 62, 249-255.
    • (1979) J Natl Cancer Inst , vol.62 , pp. 249-255
    • Buick, R.N.1    Messner, H.A.2    Till, J.E.3    McCulloch, E.A.4
  • 93
    • 0019995342 scopus 로고
    • Increased relative effectiveness of doxorubicin against slowly proliferating sarcoma 180 cells after prolonged drug exposure
    • 93. Ritch PS, Occhipinti SJ, Skramstad KS, et al. Increased relative effectiveness of doxorubicin against slowly proliferating sarcoma 180 cells after prolonged drug exposure. Cancer Treat Rep 1982, 66, 1159-1168.
    • (1982) Cancer Treat Rep , vol.66 , pp. 1159-1168
    • Ritch, P.S.1    Occhipinti, S.J.2    Skramstad, K.S.3
  • 94
    • 0026744656 scopus 로고
    • Doxorubicin weekly low dose administration: In vitro cytoxicity generated by the typical pharmacokinetic profile
    • 94. Milano G, Cassuto Viguier E, Fischel JL, et al. Doxorubicin weekly low dose administration: in vitro cytoxicity generated by the typical pharmacokinetic profile. Eur J Cancer 1992, 28A, 1881-1885.
    • (1992) Eur J Cancer , vol.28 A , pp. 1881-1885
    • Milano, G.1    Cassuto Viguier, E.2    Fischel, J.L.3
  • 95
    • 0029017629 scopus 로고
    • Rapid up-regulation of mdrl expression by anthracyclines in a classical multidrug-resistant cell line
    • 95. Hu XF, Slater A, Wall DM, et al. Rapid up-regulation of mdrl expression by anthracyclines in a classical multidrug-resistant cell line. Br J Cancer 1995, 71, 931-936.
    • (1995) Br J Cancer , vol.71 , pp. 931-936
    • Hu, X.F.1    Slater, A.2    Wall, D.M.3
  • 96
    • 0026577166 scopus 로고
    • A single 24h contact time with adriamycin provokes the emergence of resistant cells expressing the gp 170 protein
    • 96. Chevillard S, Vielh P, Bastian B, Coppey J. A single 24h contact time with adriamycin provokes the emergence of resistant cells expressing the gp 170 protein. Anticancer Res 1992, 12, 495-500.
    • (1992) Anticancer Res , vol.12 , pp. 495-500
    • Chevillard, S.1    Vielh, P.2    Bastian, B.3    Coppey, J.4
  • 97
    • 0026050325 scopus 로고
    • P-glycoprotein expression and schedule dependence of adriamycin cytotoxicity in human colon carcinoma cell lines
    • 97. Lai GM, Chen YN, Mickley LA, Fojo AT, Bates SE. P-glycoprotein expression and schedule dependence of adriamycin cytotoxicity in human colon carcinoma cell lines. Int J Cancer 1991, 49, 696-703.
    • (1991) Int J Cancer , vol.49 , pp. 696-703
    • Lai, G.M.1    Chen, Y.N.2    Mickley, L.A.3    Fojo, A.T.4    Bates, S.E.5
  • 98
    • 0028291536 scopus 로고
    • Cancer chemotherapy and infusional scheduling
    • 98. Anderson N, Lokich JJ. Cancer chemotherapy and infusional scheduling. Oncology Huntingt 1994, 8, 99-111.
    • (1994) Oncology Huntingt , vol.8 , pp. 99-111
    • Anderson, N.1    Lokich, J.J.2
  • 99
    • 0023176119 scopus 로고
    • Randomized comparison of three adriamycin regimens for metastatic soft tissue sarcomas
    • 99. Borden EC, Amato DA, Rosenbaum CH, et al. Randomized comparison of three adriamycin regimens for metastatic soft tissue sarcomas. J Clin Oncol 1987, 5, 840-850.
    • (1987) J Clin Oncol , vol.5 , pp. 840-850
    • Borden, E.C.1    Amato, D.A.2    Rosenbaum, C.H.3
  • 100
    • 0001547158 scopus 로고
    • Effect of doxorubicin (DOX) schedule on tumor response and survival in osteosarcoma (OS). Results of sequential trials COSS 86A-C
    • Abstract
    • 100. Bielack SS, Fuchs N, Bieling P, et al. Effect of doxorubicin (DOX) schedule on tumor response and survival in osteosarcoma (OS). Results of sequential trials COSS 86A-C. Med Pediatr Oncol 1994, 23, 176 (Abstract).
    • (1994) Med Pediatr Oncol , vol.23 , pp. 176
    • Bielack, S.S.1    Fuchs, N.2    Bieling, P.3
  • 101
    • 0001212761 scopus 로고
    • A comparative trial of three schedules for single-agent doxorubicin in advanced breast cancer. An aborted investigation
    • 101. Lokich JA, Auerbach M, Smith MA, et al. A comparative trial of three schedules for single-agent doxorubicin in advanced breast cancer. An aborted investigation. J Infus Chemo 1992, 2, 185-188.
    • (1992) J Infus Chemo , vol.2 , pp. 185-188
    • Lokich, J.A.1    Auerbach, M.2    Smith, M.A.3
  • 102
    • 0026750505 scopus 로고
    • Doxorubicin in advanced breast cancer: Influence of schedule on response, survival and quality of life
    • 102. Richards MA, Hopwood P, Ramirez AJ, et al. Doxorubicin in advanced breast cancer: influence of schedule on response, survival and quality of life. Eur J Cancer 1992, 28A, 1023-1028.
    • (1992) Eur J Cancer , vol.28 A , pp. 1023-1028
    • Richards, M.A.1    Hopwood, P.2    Ramirez, A.J.3
  • 104
    • 0027177275 scopus 로고
    • A randomised study of bolus vs continuous pump infusion of ifosfamide and doxorubicin with oral etoposide for small cell lung cancer
    • 104. Anderson H, Hopwood P, Prendiville J, Radford JA, Thatcher N, Ashcroft L. A randomised study of bolus vs continuous pump infusion of ifosfamide and doxorubicin with oral etoposide for small cell lung cancer. Br J Cancer 1993, 67, 1385-1390.
    • (1993) Br J Cancer , vol.67 , pp. 1385-1390
    • Anderson, H.1    Hopwood, P.2    Prendiville, J.3    Radford, J.A.4    Thatcher, N.5    Ashcroft, L.6
  • 105
    • 0027948376 scopus 로고
    • Randomized trial comparing weekly versus 3-week chemotherapy in small-cell lung cancer: A cancer research campaign trial
    • 105. Souhami RL, Rudd R, Ruiz de Elvira MC, et al. Randomized trial comparing weekly versus 3-week chemotherapy in small-cell lung cancer: a Cancer Research Campaign trial. J Clin Oncol 1994, 12, 1806-1813.
    • (1994) J Clin Oncol , vol.12 , pp. 1806-1813
    • Souhami, R.L.1    Rudd, R.2    Ruiz De Elvira, M.C.3
  • 106
    • 0027488737 scopus 로고
    • Multiple-drug weekly chemotherapy versus standard combination regimen in small-cell lung cancer: A phase III randomized study conducted by the European lung cancer working party
    • 106. Sculier JP, Paesmans M, Bureau G, et al. Multiple-drug weekly chemotherapy versus standard combination regimen in small-cell lung cancer: a phase III randomized study conducted by the European Lung Cancer Working Party. J Clin Oncol 1993, 11, 1858-1865.
    • (1993) J Clin Oncol , vol.11 , pp. 1858-1865
    • Sculier, J.P.1    Paesmans, M.2    Bureau, G.3
  • 107
    • 85004959323 scopus 로고
    • Prospective randomized trial of adjuvant adriamycin (A) by bolus (B) vs 72-hour continuous infusion (CI) in patients (PTS) with high grade soft tissue sarcoma (HGS)
    • 107. Casper E, Magill G, Freidrich C, Gaynor J, Hajdu S, Brennan M. Prospective randomized trial of adjuvant adriamycin (A) by bolus (B) vs 72-hour continuous infusion (CI) in patients (PTS) with high grade soft tissue sarcoma (HGS). Proc Annu Meet Am Soc Clin Oncol 1989, 8, A1246.
    • (1989) Proc Annu Meet Am Soc Clin Oncol , vol.8
    • Casper, E.1    Magill, G.2    Freidrich, C.3    Gaynor, J.4    Hajdu, S.5    Brennan, M.6
  • 108
    • 0029087491 scopus 로고
    • Adjuvant chemotherapy for soft-tissue sarcoma: Review and meta-analysis of the published results of randomised clinical trials
    • 108. Tierney JF, Mosseri V, Stewart LA, Souhami RL, Parmar MKB. Adjuvant chemotherapy for soft-tissue sarcoma: review and meta-analysis of the published results of randomised clinical trials. Br J Cancer 1995, 72, 469-475.
    • (1995) Br J Cancer , vol.72 , pp. 469-475
    • Tierney, J.F.1    Mosseri, V.2    Stewart, L.A.3    Souhami, R.L.4    Parmar, M.K.B.5
  • 109
    • 4244143999 scopus 로고
    • Continuous infusion (CI) versus short term infusion (SI) of doxorubicin (DOX) in osteosarcoma
    • 109. Bieling P, Winkler K, Bielack S, et al. Continuous infusion (CI) versus short term infusion (SI) of doxorubicin (DOX) in osteosarcoma. Proc Annu Meet Am Soc Clin Oncol 1991, 10, 308A.
    • (1991) Proc Annu Meet Am Soc Clin Oncol , vol.10
    • Bieling, P.1    Winkler, K.2    Bielack, S.3
  • 110
    • 0025999634 scopus 로고
    • Influence of doxorubicin dose intensity on response and outcome for patients with osteogenic sarcoma and Ewing's sarcoma
    • 110. Smith MA, Ungerleider RS, Horowitz ME, Simon R. Influence of doxorubicin dose intensity on response and outcome for patients with osteogenic sarcoma and Ewing's sarcoma. J Natl Cancer Inst 1991, 83, 1460-1470.
    • (1991) J Natl Cancer Inst , vol.83 , pp. 1460-1470
    • Smith, M.A.1    Ungerleider, R.S.2    Horowitz, M.E.3    Simon, R.4
  • 111
    • 0026519496 scopus 로고
    • Preoperative chemotherapy for osteosarcoma with intravenous adriamycin and intra-arterial cisplatinum
    • 111. Benjamin RS, Chawla SP, Carrasco CH, et al. Preoperative chemotherapy for osteosarcoma with intravenous adriamycin and intra-arterial cisplatinum. Ann Oncol 1992, 3, 3-6.
    • (1992) Ann Oncol , vol.3 , pp. 3-6
    • Benjamin, R.S.1    Chawla, S.P.2    Carrasco, C.H.3
  • 112
    • 0027401505 scopus 로고
    • Influence of treatment schedule on toxicity and efficacy of cyclophosphamide, epirubicin, and fluorouracil in metastatic breast cancer. A randomized trial comparing weekly and every-4-week administration
    • 112. Blomqvist C, Elooma I, Rissanen P, Hietanen P, Nevasaari K, Helle L. Influence of treatment schedule on toxicity and efficacy of cyclophosphamide, epirubicin, and fluorouracil in metastatic breast cancer. A randomized trial comparing weekly and every-4-week administration. J Clin Oncol 1993, 11, 467-473.
    • (1993) J Clin Oncol , vol.11 , pp. 467-473
    • Blomqvist, C.1    Elooma, I.2    Rissanen, P.3    Hietanen, P.4    Nevasaari, K.5    Helle, L.6
  • 113
    • 0000706985 scopus 로고
    • A comparison of response, survival and quality of life (QOL) using 2 doxorubicin schedules of equal dose intensity in metastatic breast cancer
    • 113. Twelves CJ, Ramirez AJ, Richards MA, et al. A comparison of response, survival and quality of life (QOL) using 2 doxorubicin schedules of equal dose intensity in metastatic breast cancer. Br J Cancer 1990, 62, 498-499.
    • (1990) Br J Cancer , vol.62 , pp. 498-499
    • Twelves, C.J.1    Ramirez, A.J.2    Richards, M.A.3
  • 114
    • 0026355059 scopus 로고
    • A randomised study of intravenous bolus vs continuous infusion of ifosfamide and doxorubicin with oral etoposide for small cell lung cancer
    • 114. Anderson H, Prendiville J, Thatcher N, Radford JA, Swindell R. A randomised study of intravenous bolus vs continuous infusion of ifosfamide and doxorubicin with oral etoposide for small cell lung cancer. J Cancer Res Clin Oncol 1991, 117 (Suppl. IV), S139-S140.
    • (1991) J Cancer Res Clin Oncol , vol.117 , Issue.SUPPL. IV
    • Anderson, H.1    Prendiville, J.2    Thatcher, N.3    Radford, J.A.4    Swindell, R.5
  • 115
    • 0021353428 scopus 로고
    • Relationship between plasma adriamycin level and the outcome of remission induction therapy for acute non-lymphocytic leukemia
    • 115. Preisler HD, Gessner T, Azarnia N, et al. Relationship between plasma adriamycin level and the outcome of remission induction therapy for acute non-lymphocytic leukemia. Cancer Chemother Pharmacol 1984, 12, 125-130.
    • (1984) Cancer Chemother Pharmacol , vol.12 , pp. 125-130
    • Preisler, H.D.1    Gessner, T.2    Azarnia, N.3
  • 116
    • 0024595921 scopus 로고
    • Fractionated anthracycline therapy in acute myeloblastic leukemia in adults
    • 116. Donohue SM, Boughton BJ. Fractionated anthracycline therapy in acute myeloblastic leukemia in adults. Cancer Chemother Pharmacol 1989, 23, 401-402.
    • (1989) Cancer Chemother Pharmacol , vol.23 , pp. 401-402
    • Donohue, S.M.1    Boughton, B.J.2
  • 117
    • 0026801086 scopus 로고
    • Continuous-infusion daunorubicin and carboplatin for high-risk acute myeloid leukemia in the elderly
    • 117. Archimbaud E, Anglaret B, Thomas X, et al. Continuous-infusion daunorubicin and carboplatin for high-risk acute myeloid leukemia in the elderly. Leukemia 1992, 6, 776-779.
    • (1992) Leukemia , vol.6 , pp. 776-779
    • Archimbaud, E.1    Anglaret, B.2    Thomas, X.3
  • 118
    • 0028968526 scopus 로고
    • The treatment of older adult patients with acute myeloid leukemia by triple infusion chemotherapy
    • 118. Friedenberg WR, Miller HJ, Marx JJ, et al. The treatment of older adult patients with acute myeloid leukemia by triple infusion chemotherapy. Am J Clin Oncol 1995, 18, 105-110.
    • (1995) Am J Clin Oncol , vol.18 , pp. 105-110
    • Friedenberg, W.R.1    Miller, H.J.2    Marx, J.J.3
  • 119
    • 0021947221 scopus 로고
    • Daunomycin administered by continuous infusion is effective in the treatment of acute non-lymphocytic leukemia
    • 119. Lewis JP, Meyers FJ, Tanaken L. Daunomycin administered by continuous infusion is effective in the treatment of acute non-lymphocytic leukemia. Br J Haematol 1985, 61, 261-265.
    • (1985) Br J Haematol , vol.61 , pp. 261-265
    • Lewis, J.P.1    Meyers, F.J.2    Tanaken, L.3
  • 120
    • 85030277928 scopus 로고
    • Daunorubicin-induced cell kill with 1-hour vs. 24-hour infusions: Randomized comparison in newly diagnosed children with acute lymphoblastic leukemia
    • Vienna, 28 August-3 September
    • 120. Janka GE, Harms D, Schwamborn D, et al. Daunorubicin-induced cell kill with 1-hour vs. 24-hour infusions: randomized comparison in newly diagnosed children with acute lymphoblastic leukemia. Proceedings of the XIIth Meeting of the International Society of Hematology. Vienna, 28 August-3 September 1993.
    • (1993) Proceedings of the XIIth Meeting of the International Society of Hematology
    • Janka, G.E.1    Harms, D.2    Schwamborn, D.3
  • 121
    • 0027448886 scopus 로고
    • Development of a new intensive therapy for acute lymphoblastic leukemia in children at increased risk of early relapse. The Memorial Sloan-Kettering-New York-II protocol
    • 121. Steinherz PG, Redner A, Steinherz L, Meyers P, Tan C, Heller G. Development of a new intensive therapy for acute lymphoblastic leukemia in children at increased risk of early relapse. The Memorial Sloan-Kettering-New York-II protocol. Cancer 1993, 72, 3120-3130.
    • (1993) Cancer , vol.72 , pp. 3120-3130
    • Steinherz, P.G.1    Redner, A.2    Steinherz, L.3    Meyers, P.4    Tan, C.5    Heller, G.6
  • 122
    • 0028938541 scopus 로고
    • Induction toxicity in acute lymphoblastic leukemia: A comparison of two schedules of daunorubicin administration
    • 122. Shaw PJ, Eden T, Paradisis M. Induction toxicity in acute lymphoblastic leukemia: a comparison of two schedules of daunorubicin administration. Med Pediatr Oncol 1995, 24, 18-22.
    • (1995) Med Pediatr Oncol , vol.24 , pp. 18-22
    • Shaw, P.J.1    Eden, T.2    Paradisis, M.3
  • 123
    • 0027238029 scopus 로고
    • Infusional cyclophosphamide, doxorubicin, and etoposide in relapsed and resistant non-Hodgkin's lymphoma: Evidence for a schedule-dependent effect favoring infusional administration of chemotherapy
    • 123. Sparano JA, Wiernik PH, Leaf A, Dutcher JP. Infusional cyclophosphamide, doxorubicin, and etoposide in relapsed and resistant non-Hodgkin's lymphoma: evidence for a schedule-dependent effect favoring infusional administration of chemotherapy. J Clin Oncol 1993, 11, 1071-1079.
    • (1993) J Clin Oncol , vol.11 , pp. 1071-1079
    • Sparano, J.A.1    Wiernik, P.H.2    Leaf, A.3    Dutcher, J.P.4
  • 124
    • 0028938612 scopus 로고
    • Infusional chemotherapy (EPOCH) in patients with refractory or relapsed lymphoma
    • 124. Carrion JR, Garcia-Arroyo FR, Saunas P. Infusional chemotherapy (EPOCH) in patients with refractory or relapsed lymphoma. Am J Clin Oncol 1995, 18, 44-16.
    • (1995) Am J Clin Oncol , vol.18 , pp. 44-116
    • Carrion, J.R.1    Garcia-Arroyo, F.R.2    Saunas, P.3
  • 125
    • 0024417601 scopus 로고
    • A randomized trial to evaluate the effect of schedule on the activity of etoposide in small cell lung cancer
    • 125. Slevin ML, Clark PL, Joel SP, et al. A randomized trial to evaluate the effect of schedule on the activity of etoposide in small cell lung cancer. J Clin Oncol 1989, 7, 1333-1339.
    • (1989) J Clin Oncol , vol.7 , pp. 1333-1339
    • Slevin, M.L.1    Clark, P.L.2    Joel, S.P.3
  • 126
    • 0028872645 scopus 로고
    • VAD chemotherapy as remission induction for multiple myeloma
    • 126. Anderson H, Scarffe JH, Ranson M, et al. VAD chemotherapy as remission induction for multiple myeloma. Br J Cancer 1995, 71, 326-330.
    • (1995) Br J Cancer , vol.71 , pp. 326-330
    • Anderson, H.1    Scarffe, J.H.2    Ranson, M.3
  • 127
    • 0021322023 scopus 로고
    • Effective treatment of advanced multiple myeloma refractory to alkylating agents
    • 127. Barlogie B, Smith L, Alexanian R. Effective treatment of advanced multiple myeloma refractory to alkylating agents. N Engl J Med 1984, 310, 1353-1356.
    • (1984) N Engl J Med , vol.310 , pp. 1353-1356
    • Barlogie, B.1    Smith, L.2    Alexanian, R.3
  • 128
    • 0026498135 scopus 로고
    • Modified adriamycin-vincristine-dexamethasone (m-VAD) in primary refractory and relapsed plasma cell myeloma: An NCI (Canada) pilot study
    • 128. Browman GP, Belch A, Shillings J, Wilson K, Bergsagel D. Modified adriamycin-vincristine-dexamethasone (m-VAD) in primary refractory and relapsed plasma cell myeloma: an NCI (Canada) pilot study. Br J Haematol 1992, 82, 555-559.
    • (1992) Br J Haematol , vol.82 , pp. 555-559
    • Browman, G.P.1    Belch, A.2    Shillings, J.3    Wilson, K.4    Bergsagel, D.5
  • 129
    • 0027199752 scopus 로고
    • VAD regimen in the treatment of resistant multiple myeloma: Slow or fast infusion?
    • 129. Koskela K, Pelliniemi TT, Remes K. VAD regimen in the treatment of resistant multiple myeloma: slow or fast infusion? Leuk Lymphoma 1993, 10, 347-351.
    • (1993) Leuk Lymphoma , vol.10 , pp. 347-351
    • Koskela, K.1    Pelliniemi, T.T.2    Remes, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.