Radiosynthesis and evaluation of two novel 123I-labeled 2-methyl-4-nitroimidazole derivatives as potential infection imaging agents

Nuclear Medicine and Biology

Volumn 32, Issue 4, 2005, Pages 385-394

  Rossouw, Daniel D ^a   Lötter, Mattheus G ^b   Du Raan, Hanlie ^b   Jansen, Susara E ^b   Höhn, Alexander ^a   Burger, Ben V ^c  

^a ITHEMBA LABS   (South Africa)

^b UNIVERSITY OF THE FREE STATE   (South Africa)

^c STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

2 Methyl 4 nitroimidazoles; 123I; Imaging; Infection; Radiosynthesis

Indexed keywords

1 [(1 HYDROXY 3 IODOPROP 2 YLOXY)METHYL] 2 METHYL 4 NITROIMIDAZOLE I 123; 1 [(1 IODOPROP 2 YLOXY)METHYL] 2 METHYL 4 NITROIMIDAZOLE I 123; GALLIUM 67; HALOGEN; IODIDE; NITROIMIDAZOLE DERIVATIVE; ORNIDAZOLE I 123; TRACER; TRIFLUOROMETHANESULFONIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG SCREENING; DRUG STABILITY; DRUG SYNTHESIS; DRUG UPTAKE; ESCHERICHIA COLI; FEMALE; ISOTOPE LABELING; MALE; NONHUMAN; RABBIT; RADIOIODINATION; RAT; SCINTILLATION CAMERA;

ANIMALS; CITRATES; DRUG EVALUATION, PRECLINICAL; ESCHERICHIA COLI INFECTIONS; FEASIBILITY STUDIES; FEMALE; GALLIUM; IODINE RADIOISOTOPES; MALE; METABOLIC CLEARANCE RATE; NITROIMIDAZOLES; ORNIDAZOLE; RABBITS; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 18844452979     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2005.02.001     Document Type: Article

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