Expression of genes for orthopoxviral TNF-binding proteins in insect cells and investigation of the recombinant TNF-binding proteins

Molecular Biology

Volumn 39, Issue 2, 2005, Pages 218-225

  Gileva, I P ^a   Ryazankin, I A ^a   Nepomnyashchikh, T S ^a   Totmenin, A V ^a   Maxutov, Z A ^a   Lebedev, L R ^a   Afinogenova, G N ^a   Pustoshilova, N M ^a   Shchelkunov, S N ^a  

^a STATE RESEARCH CENTER OF VIROLOGY AND BIOTECHNOLOGY VECTOR   (Russian Federation)

Author keywords

Orthopoxviruses; Tumor necrosis factor; Viroceptors

Indexed keywords

RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR ANTIBODY; TUMOR NECROSIS FACTOR BINDING PROTEIN; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; BINDING KINETICS; CONTROLLED STUDY; COWPOX VIRUS; CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; INSECT CELL; MONKEYPOX VIRUS; MOUSE; NONHUMAN; ORTHOPOXVIRUS; PHYSICAL CHEMISTRY; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PURIFICATION; SMALLPOX VIRUS; VIRUS GENE; VIRUS GENOME; VIRUS ISOLATION;

COWPOX VIRUS; INSECTA; MONKEYPOX VIRUS; MURINAE; ORYCTOLAGUS CUNICULUS; UNIDENTIFIED BACULOVIRUS; VARIOLA; VARIOLA VIRUS;

EID: 18844445619     PISSN: 00268933     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11008-005-0032-x     Document Type: Article

References (40)

1. Nash P., Barrett J., Cao J.X., Hota-Mitchell S., Lalani A.S., Everett H., Xu X.M., Robichaud J., Hnatuk S., Ainslie C., Seet B.T., McFadden G. 1999. Immunomodulation by viruses: The myxoma story. Immunol. Rev. 168, 103-120.
2. Johnston J.B., McFadden G. 2003. Poxvirus immunomodulatory strategies: Current perspectives. J. Virol. 77, 6093-6100.
3. Alcami A., Koszinowski U.H. 2000. Viral mechanisms of immune evasion. Trends Microbiol. 8, 410-418.
4. Ruby J., Bluethmann H., Peschon J. 1997. Antiviral activity of tumor necrosis factor (TNF) is mediated via p55 and p75 TNF receptors. J. Exp. Med. 186, 1591-1596.
5. Upton C., Macen J.L., Schreiber M., McFadden G. 1991. Myxoma virus expressed a secreted protein with homology to the tumor necroses factor gene family that contributes to viral virulence. Virology. 184, 370-382.
6. Alcami A., Khanna A., Paul N.L., Smith G.L. 1999. Vaccinia virus strains Lister, USSR and Evans express soluble and cell-surface tumor necrosis factor receptors. J. Gen. Virol. 80, 949-959.
7. Shchelkunov S.N., Safronov P.F., Totmenin A.V., Petrov N.A., Ryazankina O.I., Gutorov V.V., Kotwal G.J. 1998. The genomic sequence analysis of the left and right species-specific terminal region of cowpox virus strain reveals unique sequences and cluster of intact ORFs for immunomodulatory and host range proteins. Virology. 243, 361-386.
8. Hu F.Q., Smith C.A., Pichup J. 1994. Cowpox virus contains two copies of an early gene encoding a soluble secreted form of the type II TNF receptor. Virology. 204, 343-356.
9. Smith C.A., Hu F.Q., Smith T.D., Richards C.L., Smolak P., Goodwin R.G., Pickup D.J. 1996. Cowpox virus genome encodes a second soluble homologue of cellular TNF receptors, distinct from CrmB that binds TNF but not LT alpha. Virology. 223, 132-147.
10. Loparev V.N., Parson J.M., Knight J.C., Panus J.F., Ray C.A., Buller R.M.L., Pickup D.J., Esposito J.J. 1998. A third distinct tumor necrosis factor receptor of orthopoxviruses. Proc. Natl. Acad. Sci. USA. 95, 3786-3791.
11. Saraeva M., Alcami A. 2001. CrmE, a novel soluble tumor necrosis factor receptor encoded by poxviruses. J. Virol. 75, 226-233.
12. Shchelkunov S.N., Totmenin A.V., Babkin I.V., Safronov P.F., Ryazankina O.I., Petrov N.A., Gutorov V.V., Uvarova E.A., Mikheev M.V., Sisler J.R., Esposito J.J., Jahrling P.B., Moss B., Sandakhchiev L.S. 2001. Human monkeypox and smallpox viruses: Genomic comparison. FEBS Lett. 509, 66-70.
13. Shchelkunov S.N., Totmenin A.V., Safronov P.F., Gutorov V.V., Ryazankina O.I., Petrov N.A., Babkon I.V., Uvarova E.A., Mikheev M.V., Sandakhchiev L.S. 2002. Multiple genetic differences between the genomes of monkeypox and smallpox viruses. Dokl. Akad. Nauk. 384, 143-147.
14. Shchelkunov S.N., Totmenin A.V., Safronov P.F., Mikheev M.V., Gutorov V.V., Ryazankina O.I., Petrov N.A., Babkin I.V., Uvarova E.A., Sandakhchiev L.S., Sisler J.R., Esposito J.J., Damon I.K., Jahrling P.B., Moss B. 2002. Analysis of the monkeypox virus genome. Virology. 297, 172-194.
15. Pustoshilova N.M., Kileva E.V., Denisova L.Ya., Shingareva N.V., Masycheva V.I., Korobko V.G., Denisov L.A., Sandakhchiev L.S., Kalinin Yu.T. 1994. Russian Patent 1438240.
16. Korobko V.G., Dobrynin V.N., Filippov S.A., Shingarove L.N., Chuvpilo S.A., Boldyreva E.F., Kravchenko V.V., Shakhov A.N., Nedospasov S.A., Turetskaya R.I. 1994. Russian Patent 1445193.
17. Bradford M.M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
18. Breslauer K.J., Frank R., Blocher H., Marky L.A. 1986. Predicting DNA duplex stability from the base sequence. Proc. Natl. Acad. Sci. USA. 83, 3746-3750.
19. Lebedev L.R., Ryazankin I.A., Sizov A.A., Ageenko V.A., Odegov V.N., Afinogenova G.N. 2001. A method for purifying antagonists of the tumor necrosis factor and analysis of some their properties. Biotekhnologiya. 6, 14-18.
20. Bray M., Martinez M., Kefauver D., West M., Roy C. 2002. Treatment of aerosolized cowpox virus infection in mice with aerosolized cidofovir. Antiviral Res. 54, 129-142.
21. Antibodies: A Practical Approach, Catty, D., Ed., Washington: IRL, 1989. Translated under the title Antitela, Moscow: Mir, 1991, vol. 1, p. 106.
22. Antibodies: A Practical Approach, Catty, D., Ed., Washington: IRL, 1989. Translated under the title Antitela, Moscow: Mir, 1991, vol. 1, p. 106.
23. Mikhailov A.T., Simirskii V.N. 1991. Metody immunokhimicheskogo analiza v biologii razvitiya (Methods of Immunochemical Analysis in Developmental Biology), Moscow: Nauka, pp. 248-249.
24. Laemmli U. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227, 680-685.
25. Burnette W.N. 1981. "Western blotting": Electrophoretic transfer of proteins from sodium dodecyl sulphate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal. Biochem. 112, 195-132.
26. Shchelkunov S.N., Blinov V.M., Totmenin A.V., Marennikova S.S., Kolykhalov A.A., Frolov I.V., Chizhikov V.E., Gutorov V.V., Gashnikov P.V., Belanov E.F. Belavin P.A., Resenchuk S.M., Shelukhina E.M., Netesov S.V., Andzhaparidze O.G., Sandakhchiev L.S. 1992. Studies on the structural-functional organization of the smallpox virus genome: 1. Cloning of HindIII and XhoI fragments of the viral DNA and sequencing of HindIII-M, -L, and -I fragments. Mol. Biol. 26, 1099-1115.
27. Ryazankina O.I., Tumanova O.Yu., Kolosova I.V., Safronov P.F., Kablova G.V., Ryazankin I.A., Shchelkunov S.N. 2000. Structural-functional organization of the GRI-90 cowpox virus genome: 1. Isolation of clones carrying DNA fragments of the complete cowpox virus genome. Mol. Biol. 34, 160-166.
28. R Baculovirus Expression System. Instruction Manual. www.invitrogen.com
29. Gileva I.L., Ryazankina I.A., Maksyutov Z.A., Totmenin A.V., Lebedev L.R., Nesterov A.E., Ageenko V.A., Shchelkunov S.N., Sandakhchiev L.S. 2003. Comparative analysis of soluble orthopoxviral receptors for tumor necrosis factor. Dokl. Akad. Nauk. 390, 160-164.
30. Ryazankina O.I., Ryzankin I.A., Ageenko V.A., Shchelkunov S.N. 1998. Expression of the tumor necrosis factor receptor-like protein of variola virus in prokaryotic and eukaryotic cells. Abstr. 10th Int. Congress of Immunology, New Delhi, India, p. 380.
31. Schreiber M., Rajarathnam K., McFadden G. 1996. Myxoma virus T2 protein, a tumor necrosis factor (TNF) receptor homolog, is secreted as a monomer and dimer that each bind rabbit TNFα, but dimer is a more potent TNF inhibitor. J. Biol. Chem. 271, 13333-13341.
32. Schreiber M., McFadden G. 1996. Mutational analysis of the ligand-binding domain of M-T2 protein, the tumor necrosis factor homologue of myxoma virus. J. Immunol. 157, 4486-4495.
33. Ashkenazi A., Marsters S.A., Capon D.J., Chamow S.M., Figari I.S., Pennica D., Goeddel D.V., Palladino M.A., Smith D.H. 1991. Protection against endotoxic shocks by tumor necrosis factor receptor immunoadhesin. Proc. Natl. Acad. Sci. USA. 88, 10535-10539.
34. Tracey K.J., Cerami A. 1994. Tumor necrosis factor: A pleiotropic cytokine and therapeutic target. Annu. Rev. Med. 45, 491-503.
35. Hasegawa A., Takasaki W., Greene M.I., Murali R. 2001. Modifying TNFα for therapeutic use: A perspective on the TNF receptor system. Mini. Rev. Med. Chem. 1, 5-16.
36. Scallon B.J., Moore M.A., Tringh H., Knight D.M., Ghrayeb J. 1995. Chimeric anti-TNF-alpha monoclonal antibody cA2 binds recombinant transmembrane TNF-alpha and activates immune effector functions. Cytokines. 7, 251-259.
37. Mohler K.M., Torrance D.S., Smith C.A., Goodwing R.G., Stremler K.E., Fung V.P., Madani H., Widmer M.B. 1993. Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists. J. Immunol. 151, 1548-1561.
38. Scallon B.J., Trinh T., Nedelman M., Brennan F.M., Feldman M., Ghrayeb J. 1995. Functional comparisons of different tumor necrosis factor receptor/IgG fusion proteins. Cytokines. 7, 759-770.
39. Moreland L.W., Baumgartner S.W., Schiff M.H., Tindall E.A., Fleischmann R.M., Weaver A.L., Ettlinger R.E., Cohen S., Koopman W.J., Mohler K., Widmer M.B., Blosch C.M. 1997. Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N. Engl. J. Med. 337, 141-147.
40. Fisher C.J., Agosti J.M., Opal S.M., M.D., Lowry S.F., Balk R.A., Sadoff J.C., Abraham E., Schein R.M.H., Benjamin E. 1996. Treatment of septic shock with the tumor necrosis factor receptor: Fc fusion protein. N. Engl. J. Med. 334, 1697-1702.