Excess visceral and hepatic adipose tissue in Turner syndrome determined by magnetic resonance imaging: Estrogen deficiency associated with hepatic adipose content

Journal of Clinical Endocrinology and Metabolism

Volumn 90, Issue 5, 2005, Pages 2631-2635

  Ostberg, Julia E ^a   Thomas, E Louise ^b   Hamilton, Gavin ^b   Attar, M Javad Hosseinzadeh ^a   Bell, Jimmy D ^b   Conway, Gerard S ^a,c  

^a UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c MIDDLESEX HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL MARKER; ESTROGEN; LIPID;

ADULT; ANAMNESIS; ANTHROPOMETRY; ARTICLE; ATHEROSCLEROSIS; BODY DISTRIBUTION; BODY FAT; BODY HEIGHT; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ESTROGEN DEFICIENCY; FATTY LIVER; FEMALE; HUMAN; HYPOINSULINEMIA; IMPEDANCE; METABOLIC SYNDROME X; NUCLEAR MAGNETIC RESONANCE IMAGING; OBESITY; PRIORITY JOURNAL; RISK FACTOR; SUBCUTANEOUS FAT; TISSUE DISTRIBUTION; TURNER SYNDROME; VISCERA;

ADIPOSE TISSUE; ADULT; ELECTRIC IMPEDANCE; ESTROGENS; FEMALE; HUMANS; LIVER; MAGNETIC RESONANCE IMAGING; TURNER SYNDROME; VISCERA;

EID: 18844443687     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2004-1939     Document Type: Article

References (21)

1. Gravholt CH, Juul S, Naeraa RW, Hansen J 1998 Morbidity in Turner syndrome. J Clin Epidemiol 51:147-158
2. Swerdlow AJ, Hermon C, Jacobs PA, Alberman E, Beral V, Daker M, Fordyce A, Youings S 2001 Mortality and cancer incidence in persons with numerical sex chromosome abnormalities: a cohort study. Ann Hum Genet 65:177-188
3. Naeraa RW, Gravholt CH, Hansen J, Nielsen J, Juul S 1995 Mortality in Turner syndrome. In: Albertsson-Wikland K, Ranke M, eds. Turner syndrome in a life-span perspective: research and clinical aspects. Amsterdam: Elsevier Science; Excerpt Med Int Congr Ser 1089:323
4. Ross JL, Feuillan P, Long LM, Kowal K, Kushner H, Cutler Jr GB 1995 Lipid abnormalities in Turner syndrome. J Pediatr 126:242-245
5. Elsheikh M, Conway GS 1998 The impact of obesity on cardiovascular risk factors in Turner's syndrome. Clin Endocrinol (Oxf) 49:447-450
6. Gravholt CH, Naeraa RW, Nyholm B, Gerdes LU, Christiansen E, Schmitz O, Christiansen JS 1998 Glucose metabolism, lipid metabolism, and cardiovascular risk factors in adult Turner's syndrome. The impact of sex hormone replacement. Diabetes Care 21:1062-1070
7. Bakalov VK, Cooley MM, Quon MJ, Luo ML, Yanovski JA, Nelson LM, Sullivan G, Bondy C 2004 Impaired insulin secretion in the Turner metabolic syndrome. J Clin Endocrinol Metab 89:3516-3520
8. Thomas EL, Saeed N, Hajnal JV, Brynes A, Goldstone AP, Frost G, Bell JD 1998 Magnetic resonance imaging of total body fat. J Appl Physiol 85:1778-1785
9. Jebb SA, Cole TJ, Doman D, Murgatroyd PR, Prentice AM 2000 Evaluation of the novel Tanita body-fat analyser to measure body composition by comparison with a four-compartment model. Br J Nutr 83:115-122
10. McGarry JD 2002 Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes 51:7-18
11. Frayn KN 2003 The glucose-fatty acid cycle: a physiological perspective. Biochem Soc Trans 31:1115-1119
12. Ross R 2003 Advances in the application of imaging methods in applied and clinical physiology. Acta Diabetol 40(Suppl 1):S45-S50
13. Thomas EL, Brynes AE, McCarthy J, Goldstone AP, Hajnal JV, Saeed N, Frost G, Bell JD 2000 Preferential loss of visceral fat following aerobic exercise, measured by magnetic resonance imaging. Lipids 35:769-776
14. Thomas EL, Hamilton G, Patel N, O'Dwyer R, Doré CJ, Bell JD, Taylor-Robinson SD 2005 Hepatic triglyceride content and its relation to body adiposity: a MRI and 1H MRS study. Gut 54:122-127
15. Rico-Sanz J, Hajnal JV, Thomas EL, Mierisova S, Ala-Korpela M, Bell JD 1998 Intracellular and extracellular skeletal muscle triglyceride metabolism during alternating intensity exercise in humans. J Physiol 510:615-622
16. Elsheikh M, Hodgson HJ, Wass JA, Conway GS 2001 Hormone replacement therapy may improve hepatic function in women with Turner's syndrome. Clin Endocrinol (Oxf) 55:227-231
17. Guttmann H, Weiner Z, Nikolski E, Ish-Shalom S, Itskovitz-Eldor J, Aviram M, Reisner S, Hochberg Z 2001 Choosing an oestrogen replacement therapy in young adult women with Turner syndrome. Clin Endocrinol (Oxf) 54:159-164
18. Roulot D, Degott C, Chazouilleres O, Oberti F, Cales P, Carbonell N, Benferhat S, Bresson-Hadni S, Valla D 2004 Vascular involvement of the liver in Turner's syndrome. Hepatology 39:239-247
19. Danforth Jr E 2000 Failure of adipocyte differentiation causes type II diabetes mellitus? Nat Genet 26:13
20. Unger RH 2002 Lipotoxic diseases. Annu Rev Med 53:319-336
21. Elsheikh M, Dunger DB, Conway GS, Wass JA 2002 Turner's syndrome in adulthood. Endocr Rev 23:120-140