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Volumn 91, Issue 2, 2005, Pages 133-144

Characterization of a human breast cancer cell line, MCF-7/RU58 R-1, resistant to the pure antiestrogen RU 58,668

Author keywords

Antiestrogen resistance; Breast cancer; Endocrine therapy; Estrogen receptor; ICI 182,780; PSK 3668; Pure antiestrogens; RU 58,668; Tamoxifen

Indexed keywords

11 [4 [[5 [(4,4,5,5,5 PENTAFLUOROPENTYL)SULFONYL]PENTYL]OXY]PHENYL] ESTRADIOL; 11 [4 [[5 [(4,4,5,5,5 PENTAFLUOROPENTYL)SULFONYL]PENTYL]OXY]PHENYL]ESTRADIOL; ANTIESTROGEN; CONNECTIVE TISSUE GROWTH FACTOR; ESTROGEN; ESTROGEN RECEPTOR ALPHA; FULVESTRANT; PROGESTERONE RECEPTOR; PROTEIN BCL 2; SOMATOMEDIN C RECEPTOR; TAMOXIFEN; UNCLASSIFIED DRUG;

EID: 18844379920     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-004-5871-y     Document Type: Article
Times cited : (11)

References (46)
  • 1
    • 0036488531 scopus 로고    scopus 로고
    • Endocrine-responsive breast cancer and strategies for combating resistance
    • S Ali RC Coombes 2002 Endocrine-responsive breast cancer and strategies for combating resistance Nat Rev Cancer 2 101 112
    • (2002) Nat Rev Cancer , vol.2 , pp. 101-112
    • Ali, S.1    Coombes, R.C.2
  • 4
    • 0037468902 scopus 로고    scopus 로고
    • Antiestrogens and selective estrogen receptor modulators as multifunctional medicines 2. Clinical considerations and new agents
    • VC Jordan 2003 Antiestrogens and selective estrogen receptor modulators as multifunctional medicines 2. Clinical considerations and new agents J Med Chem 46 1081 1111
    • (2003) J Med Chem , vol.46 , pp. 1081-1111
    • Jordan, V.C.1
  • 5
    • 0036998677 scopus 로고    scopus 로고
    • Fulvestrant ('Faslodex') - A new treatment option for patients progressing on prior endocrine therapy
    • C Morris A Wakeling 2002 Fulvestrant ('Faslodex') - a new treatment option for patients progressing on prior endocrine therapy Endocr Relat Cancer 9 267 276
    • (2002) Endocr Relat Cancer , vol.9 , pp. 267-276
    • Morris, C.1    Wakeling, A.2
  • 7
    • 18844454130 scopus 로고    scopus 로고
    • Postmenopausal woman with advanced breast cancer who have progresed after Fulvestrant (Faslodex) remain sensitive to other endocrine agents
    • S96-abstract 216
    • Vergote I: Postmenopausal woman with advanced breast cancer who have progresed after Fulvestrant (Faslodex) remain sensitive to other endocrine agents. Eu J Cancer 38 (Suppl 3), S96-abstract 216, 2003
    • (2003) Eu J Cancer , vol.38 , Issue.3 SUPPL.
    • Vergote, I.1
  • 8
    • 0026395885 scopus 로고
    • A potent specific pure antiestrogen with clinical potential
    • AE Wakeling M Dukes J Bowler 1991 A potent specific pure antiestrogen with clinical potential Cancer Res 51 3867 3873
    • (1991) Cancer Res , vol.51 , pp. 3867-3873
    • Wakeling, A.E.1    Dukes, M.2    Bowler, J.3
  • 9
    • 0032230245 scopus 로고    scopus 로고
    • Interaction and dissociation by ligands of estrogen receptor and HSP90: The antiestrogen RU 58668 induces a protein synthesis-dependent clustering of the receptor in the cytoplasm
    • J Devin-Leclerc X Meng F Delahaye P Leclerc EE Baulieu MG Catelli 1998 Interaction and dissociation by ligands of estrogen receptor and HSP90: the antiestrogen RU 58668 induces a protein synthesis-dependent clustering of the receptor in the cytoplasm Mol Endocrinol 12 842 854
    • (1998) Mol Endocrinol , vol.12 , pp. 842-854
    • Devin-Leclerc, J.1    Meng, X.2    Delahaye, F.3    Leclerc, P.4    Baulieu, E.E.5    Catelli, M.G.6
  • 10
    • 0027768899 scopus 로고
    • The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling
    • S Dauvois R White MG Parker 1993 The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling J Cell Sci 106 1377 1388
    • (1993) J Cell Sci , vol.106 , pp. 1377-1388
    • Dauvois, S.1    White, R.2    Parker, M.G.3
  • 11
    • 0142056952 scopus 로고    scopus 로고
    • Various phosphorylation pathways, depending on agonist and antagonist binding to endogenous estrogen receptor alpha (ER alpha), differentially affect ER alpha extractability, proteasome-mediated stability and transcriptional activity in human breast cancer cells
    • V Marsaud A Gougelet S Maillard JM Renoir 2003 Various phosphorylation pathways, depending on agonist and antagonist binding to endogenous estrogen receptor alpha (ER alpha), differentially affect ER alpha extractability, proteasome-mediated stability and transcriptional activity in human breast cancer cells Mol Endocrinol 17 2013 2027
    • (2003) Mol Endocrinol , vol.17 , pp. 2013-2027
    • Marsaud, V.1    Gougelet, A.2    Maillard, S.3    Renoir, J.M.4
  • 12
    • 0026560435 scopus 로고
    • Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover
    • S Dauvois PS Danielian R White MG Parker 1992 Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover Proc Natl Acad Sci USA 89 4037 4041
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4037-4041
    • Dauvois, S.1    Danielian, P.S.2    White, R.3    Parker, M.G.4
  • 14
    • 0030511946 scopus 로고    scopus 로고
    • Mechanisms of tamoxifen resistance in the treatment of advanced breast cancer
    • Suppl 5
    • AE Lykkesfeldt 1996 Mechanisms of tamoxifen resistance in the treatment of advanced breast cancer Acta Oncol 35 Suppl 5 9 14
    • (1996) Acta Oncol , vol.35 , pp. 9-14
    • Lykkesfeldt, A.E.1
  • 15
    • 0033973395 scopus 로고    scopus 로고
    • Oestrogen and growth factor cross-talk and endocrine insensitivity and acquired resistance in breast cancer
    • RI Nicholson JM Gee 2000 Oestrogen and growth factor cross-talk and endocrine insensitivity and acquired resistance in breast cancer Br J Cancer 82 501 513
    • (2000) Br J Cancer , vol.82 , pp. 501-513
    • Nicholson, R.I.1    Gee, J.M.2
  • 17
    • 0348149066 scopus 로고    scopus 로고
    • Growth factor receptor cross-talk with estrogen receptor as a mechanism for tamoxifen resistance in breast cancer
    • CK Osborne R Schiff 2003 Growth factor receptor cross-talk with estrogen receptor as a mechanism for tamoxifen resistance in breast cancer Breast 12 362 367
    • (2003) Breast , vol.12 , pp. 362-367
    • Osborne, C.K.1    Schiff, R.2
  • 18
    • 0037237481 scopus 로고    scopus 로고
    • Breast cancer endocrine resistance: How growth factor signaling and estrogen receptor coregulators modulate response
    • R Schiff S Massarweh J Shou CK Osborne 2003 Breast cancer endocrine resistance: how growth factor signaling and estrogen receptor coregulators modulate response Clin Cancer Res 9 447S 454S
    • (2003) Clin Cancer Res , vol.9
    • Schiff, R.1    Massarweh, S.2    Shou, J.3    Osborne, C.K.4
  • 19
    • 0021365258 scopus 로고
    • Effect of estrogen and antiestrogen on the human breast cancer cell line MCF-7 adapted to growth at low serum concentration
    • P Briand AE Lykkesfeldt 1984 Effect of estrogen and antiestrogen on the human breast cancer cell line MCF-7 adapted to growth at low serum concentration Cancer Res 44 1114 1119
    • (1984) Cancer Res , vol.44 , pp. 1114-1119
    • Briand, P.1    Lykkesfeldt, A.E.2
  • 20
    • 0034866694 scopus 로고    scopus 로고
    • Growth inhibition and growth stimulation by estradiol of estrogen receptor transfected human breast epithelial cell lines involve different pathways
    • BK Lundholt P Briand AE Lykkesfeldt 2001 Growth inhibition and growth stimulation by estradiol of estrogen receptor transfected human breast epithelial cell lines involve different pathways Breast Cancer Res Treat 67 199 214
    • (2001) Breast Cancer Res Treat , vol.67 , pp. 199-214
    • Lundholt, B.K.1    Briand, P.2    Lykkesfeldt, A.E.3
  • 21
    • 0031051458 scopus 로고    scopus 로고
    • Estrogen receptor messenger RNA splice variants are not involved in antiestrogen resistance in sublines of MCF-7 human breast cancer cells
    • MW Madsen BE Reiter SS Larsen P Briand AE Lykkesfeldt 1997 Estrogen receptor messenger RNA splice variants are not involved in antiestrogen resistance in sublines of MCF-7 human breast cancer cells Cancer Res 57 585 589
    • (1997) Cancer Res , vol.57 , pp. 585-589
    • Madsen, M.W.1    Reiter, B.E.2    Larsen, S.S.3    Briand, P.4    Lykkesfeldt, A.E.5
  • 22
    • 0040390304 scopus 로고
    • Activation of pS2 gene transcription is a primary response to estrogen in the human breast cancer cell line MCF-7
    • AM Brown JM Jeltsch M Roberts P Chambon 1984 Activation of pS2 gene transcription is a primary response to estrogen in the human breast cancer cell line MCF-7 Proc Natl Acad Sci USA 81 6344 6348
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 6344-6348
    • Brown, A.M.1    Jeltsch, J.M.2    Roberts, M.3    Chambon, P.4
  • 23
    • 0028329961 scopus 로고
    • Altered expression of estrogen-regulated genes in a tamoxifen-resistant and ICI 164,384 and ICI 182,780 sensitive human breast cancer cell line, MCF-7/TAMR-1
    • AE Lykkesfeldt MW Madsen P Briand 1994 Altered expression of estrogen-regulated genes in a tamoxifen-resistant and ICI 164,384 and ICI 182,780 sensitive human breast cancer cell line, MCF-7/TAMR-1 Cancer Res 54 1587 1595
    • (1994) Cancer Res , vol.54 , pp. 1587-1595
    • Lykkesfeldt, A.E.1    Madsen, M.W.2    Briand, P.3
  • 24
    • 0030067040 scopus 로고    scopus 로고
    • Changes in insulin-like growth factor-I receptor expression and binding protein secretion associated with tamoxifen resistance and estrogen independence in human breast cancer cells in vitro
    • D McCotter HW van den Berg M Boylan B McKibben 1996 Changes in insulin-like growth factor-I receptor expression and binding protein secretion associated with tamoxifen resistance and estrogen independence in human breast cancer cells in vitro Cancer Lett 99 239 245
    • (1996) Cancer Lett , vol.99 , pp. 239-245
    • McCotter, D.1    Van Den Berg, H.W.2    Boylan, M.3    McKibben, B.4
  • 25
    • 15644377090 scopus 로고    scopus 로고
    • MCF7/LCC9: An antiestrogen-resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen
    • N Brünner B Boysen S Jirus TC Skaar C Holst-Hansen J Lippman T Frandsen M Spang-Thomsen SA Fuqua R Clarke 1997 MCF7/LCC9: an antiestrogen-resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen Cancer Res 57 3486 3493
    • (1997) Cancer Res , vol.57 , pp. 3486-3493
    • Brünner, N.1    Boysen, B.2    Jirus, S.3    Skaar, T.C.4    Holst-Hansen, C.5    Lippman, J.6    Frandsen, T.7    Spang-Thomsen, M.8    Fuqua, S.A.9    Clarke, R.10
  • 26
    • 0032945122 scopus 로고    scopus 로고
    • Differential regulation of specific genes in MCF-7 and the ICI 182780-resistant cell line MCF-7/182R-6
    • BL Jensen J Skouv BK Lundholt AE Lykkesfeldt 1999 Differential regulation of specific genes in MCF-7 and the ICI 182780-resistant cell line MCF-7/182R-6 Br J Cancer 79 386 392
    • (1999) Br J Cancer , vol.79 , pp. 386-392
    • Jensen, B.L.1    Skouv, J.2    Lundholt, B.K.3    Lykkesfeldt, A.E.4
  • 27
    • 0347717953 scopus 로고    scopus 로고
    • Resistance to different antiestrogens is caused by different multi-factorial changes and is associated with reduced expression of IGF receptor Ialpha
    • BL Brockdorff I Heiberg AE Lykkesfeldt 2003 Resistance to different antiestrogens is caused by different multi-factorial changes and is associated with reduced expression of IGF receptor Ialpha Endocr Relat Cancer 10 579 590
    • (2003) Endocr Relat Cancer , vol.10 , pp. 579-590
    • Brockdorff, B.L.1    Heiberg, I.2    Lykkesfeldt, A.E.3
  • 28
    • 0029059562 scopus 로고
    • Human breast cancer cell lines resistant to pure anti-estrogens are sensitive to tamoxifen treatment
    • AE Lykkesfeldt SS Larsen P Briand 1995 Human breast cancer cell lines resistant to pure anti-estrogens are sensitive to tamoxifen treatment Int J Cancer 61 529 534
    • (1995) Int J Cancer , vol.61 , pp. 529-534
    • Lykkesfeldt, A.E.1    Larsen, S.S.2    Briand, P.3
  • 29
    • 0028977917 scopus 로고
    • Antiestrogenic activity of two 11 beta-estradiol derivatives on MCF-7 breast cancer cells
    • L Jin M Borras M Lacroix N Legros G Leclercq 1995 Antiestrogenic activity of two 11 beta-estradiol derivatives on MCF-7 breast cancer cells Steroids 60 512 518
    • (1995) Steroids , vol.60 , pp. 512-518
    • Jin, L.1    Borras, M.2    Lacroix, M.3    Legros, N.4    Leclercq, G.5
  • 31
    • 0027279120 scopus 로고
    • MCF7/LCC2: A 4-hydroxytamoxifen resistant human breast cancer variant that retains sensitivity to the steroidal antiestrogen ICI 182,780
    • N Brünner TL Frandsen C Holst-Hansen M Bei EW Thompson AE Wakeling ME Lippman R Clarke 1993 MCF7/LCC2: a 4-hydroxytamoxifen resistant human breast cancer variant that retains sensitivity to the steroidal antiestrogen ICI 182,780 Cancer Res 53 3229 3232
    • (1993) Cancer Res , vol.53 , pp. 3229-3232
    • Brünner, N.1    Frandsen, T.L.2    Holst-Hansen, C.3    Bei, M.4    Thompson, E.W.5    Wakeling, A.E.6    Lippman, M.E.7    Clarke, R.8
  • 32
    • 0033060824 scopus 로고    scopus 로고
    • Implication of proteasome in estrogen receptor degradation
    • A El Khissiin G Leclercq 1999 Implication of proteasome in estrogen receptor degradation FEBS Lett 448 160 166
    • (1999) FEBS Lett , vol.448 , pp. 160-166
    • El Khissiin, A.1    Leclercq, G.2
  • 33
    • 0021927466 scopus 로고
    • Selection and characterization of a breast cancer cell line resistant to the antiestrogen LY 117018
    • DA Bronzert GL Greene ME Lippman 1985 Selection and characterization of a breast cancer cell line resistant to the antiestrogen LY 117018 Endocrinology 117 1409 1417
    • (1985) Endocrinology , vol.117 , pp. 1409-1417
    • Bronzert, D.A.1    Greene, G.L.2    Lippman, M.E.3
  • 34
    • 0031597992 scopus 로고    scopus 로고
    • The loss of estrogen and progesterone receptor gene expression in human breast cancer
    • RG Lapidus SJ Nass NE Davidson 1998 The loss of estrogen and progesterone receptor gene expression in human breast cancer J Mammary Gland Biol Neoplasia 3 85 94
    • (1998) J Mammary Gland Biol Neoplasia , vol.3 , pp. 85-94
    • Lapidus, R.G.1    Nass, S.J.2    Davidson, N.E.3
  • 35
    • 0035423119 scopus 로고    scopus 로고
    • Re-expression of estrogen receptor alpha in estrogen receptor alpha-negative MCF-7 cells restores both estrogen and insulin-like growth factor-mediated signaling and growth
    • S Oesterreich P Zhang RL Guler X Sun EM Curran WV Welshons CK Osborne AV Lee 2001 Re-expression of estrogen receptor alpha in estrogen receptor alpha-negative MCF-7 cells restores both estrogen and insulin-like growth factor-mediated signaling and growth Cancer Res 61 5771 5777
    • (2001) Cancer Res , vol.61 , pp. 5771-5777
    • Oesterreich, S.1    Zhang, P.2    Guler, R.L.3    Sun, X.4    Curran, E.M.5    Welshons, W.V.6    Osborne, C.K.7    Lee, A.V.8
  • 36
    • 0030753406 scopus 로고    scopus 로고
    • Resistance of human breast-cancer cells to the pure steroidal anti-estrogen ICI 182,780 is not associated with a general loss of estrogen-receptor expression or lack of estrogen responsiveness
    • SS Larsen MW Madsen BL Jensen AE Lykkesfeldt 1997 Resistance of human breast-cancer cells to the pure steroidal anti-estrogen ICI 182,780 is not associated with a general loss of estrogen-receptor expression or lack of estrogen responsiveness Int J Cancer 72 1129 1136
    • (1997) Int J Cancer , vol.72 , pp. 1129-1136
    • Larsen, S.S.1    Madsen, M.W.2    Jensen, B.L.3    Lykkesfeldt, A.E.4
  • 37
    • 0033870250 scopus 로고    scopus 로고
    • Long-term hydroxytamoxifen treatment of an MCF-7-derived breast cancer cell line irreversibly inhibits the expression of estrogenic genes through chromatin remodeling
    • E Badia MJ Duchesne A Semlali M Fuentes C Giamarchi H Richard-Foy JC Nicolas M Pons 2000 Long-term hydroxytamoxifen treatment of an MCF-7-derived breast cancer cell line irreversibly inhibits the expression of estrogenic genes through chromatin remodeling Cancer Res 60 4130 4138
    • (2000) Cancer Res , vol.60 , pp. 4130-4138
    • Badia, E.1    Duchesne, M.J.2    Semlali, A.3    Fuentes, M.4    Giamarchi, C.5    Richard-Foy, H.6    Nicolas, J.C.7    Pons, M.8
  • 38
    • 0037385522 scopus 로고    scopus 로고
    • Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: Progesterone receptor as a potential indicator of growth factor activity in breast cancer
    • X Cui P Zhang W Deng S Oesterreich Y Lu GB Mills AV Lee 2003 Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: progesterone receptor as a potential indicator of growth factor activity in breast cancer Mol Endocrinol 17 575 588
    • (2003) Mol Endocrinol , vol.17 , pp. 575-588
    • Cui, X.1    Zhang, P.2    Deng, W.3    Oesterreich, S.4    Lu, Y.5    Mills, G.B.6    Lee, A.V.7
  • 39
    • 0025597894 scopus 로고
    • Insulin-like growth factor binding protein secretion by breast carcinoma cell lines: Correlation with estrogen receptor status
    • DR Clemmons C Camacho-Hubner E Coronado CK Osborne 1990 Insulin-like growth factor binding protein secretion by breast carcinoma cell lines: correlation with estrogen receptor status Endocrinology 127 2679 2686
    • (1990) Endocrinology , vol.127 , pp. 2679-2686
    • Clemmons, D.R.1    Camacho-Hubner, C.2    Coronado, E.3    Osborne, C.K.4
  • 40
    • 0029129987 scopus 로고
    • Intracellular levels and secretion of insulin-like-growth-factor-binding proteins in MCF-7/6, MCF-7/AZ and MDA-MB-231 breast cancer cells. Differential modulation by estrogens in serum-free medium
    • V Dubois D Couissi E Schonne C Remacle A Trouet 1995 Intracellular levels and secretion of insulin-like-growth-factor-binding proteins in MCF-7/6, MCF-7/AZ and MDA-MB-231 breast cancer cells. Differential modulation by estrogens in serum-free medium Eur J Biochem 232 47 53
    • (1995) Eur J Biochem , vol.232 , pp. 47-53
    • Dubois, V.1    Couissi, D.2    Schonne, E.3    Remacle, C.4    Trouet, A.5
  • 41
    • 0026376263 scopus 로고
    • Differential regulation of gene expression by estrogen in estrogen growth-independent and -dependent MCF-7 human breast cancer cell sublines
    • HS Cho PA NG BS Katzenellenbogen 1991 Differential regulation of gene expression by estrogen in estrogen growth-independent and -dependent MCF-7 human breast cancer cell sublines Mol Endocrinol 5 1323 1330
    • (1991) Mol Endocrinol , vol.5 , pp. 1323-1330
    • Cho, H.S.1    PA, N.G.2    Katzenellenbogen, B.S.3
  • 42
    • 0037728640 scopus 로고    scopus 로고
    • Effect of antiestrogens and aromatase inhibitor on basal growth of the human breast cancer cell line MCF-7 in serum-free medium
    • J Jensen JW Kitlen P Briand F Labrie AE Lykkesfeldt 2003 Effect of antiestrogens and aromatase inhibitor on basal growth of the human breast cancer cell line MCF-7 in serum-free medium J Steroid Biochem Mol Biol 84 469 478
    • (2003) J Steroid Biochem Mol Biol , vol.84 , pp. 469-478
    • Jensen, J.1    Kitlen, J.W.2    Briand, P.3    Labrie, F.4    Lykkesfeldt, A.E.5
  • 43
    • 0033304585 scopus 로고    scopus 로고
    • Selective promoter usage of the human estrogen receptor-alpha gene and its regulation by estrogen
    • C Donaghue BR Westley FE May 1999 Selective promoter usage of the human estrogen receptor-alpha gene and its regulation by estrogen Mol Endocrinol 13 1934 1950
    • (1999) Mol Endocrinol , vol.13 , pp. 1934-1950
    • Donaghue, C.1    Westley, B.R.2    May, F.E.3
  • 44
    • 0025635904 scopus 로고
    • Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells
    • AJ Stewart MD Johnson FE May BR Westley 1990 Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells J Biol Chem 265 21172 21178
    • (1990) J Biol Chem , vol.265 , pp. 21172-21178
    • Stewart, A.J.1    Johnson, M.D.2    May, F.E.3    Westley, B.R.4


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