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Volumn 9, Issue 4, 2002, Pages 267-276

Fulvestrant ('Faslodex') - A new treatment option for patients progressing on prior endocrine therapy

Author keywords

[No Author keywords available]

Indexed keywords

ANASTROZOLE; AROMATASE INHIBITOR; ESTRADIOL; ESTROGEN RECEPTOR; EXEMESTANE; FULVESTRANT; IDOXIFENE; LETROZOLE; MEGESTROL ACETATE; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN; TOREMIFENE;

EID: 0036998677     PISSN: 13510088     EISSN: None     Source Type: Journal    
DOI: 10.1677/erc.0.0090267     Document Type: Review
Times cited : (62)

References (54)
  • 2
    • 0035464108 scopus 로고    scopus 로고
    • Aromatase, aromatase inhibitors, and breast cancer
    • Brueggemeier RW 2001 Aromatase, aromatase inhibitors, and breast cancer. American Journal of Therapeutics 8 333-344.
    • (2001) American Journal of Therapeutics , vol.8 , pp. 333-344
    • Brueggemeier, R.W.1
  • 3
    • 0034984594 scopus 로고    scopus 로고
    • Endocrine therapy in the treatment of metastatic breast cancer
    • Buzdar AU 2001 Endocrine therapy in the treatment of metastatic breast cancer. Seminars in Oncology 28 291-304,
    • (2001) Seminars in Oncology , vol.28 , pp. 291-304
    • Buzdar, A.U.1
  • 4
    • 0032530988 scopus 로고    scopus 로고
    • Anastrozole versus megestrol acetate in the treatment of postmenopausal women with advanced breast carcinoma: Results of a survival update based on a combined analysis of data from two mature phase III trials
    • Arimidex Study Group
    • Buzdar AU, Jonat W, Howell A, Jones SE, Blomqvist CP, Vogel CL, Eiermann W, Wolter JM, Steinberg M, Webster A & Lee D 1998 Anastrozole versus megestrol acetate in the treatment of postmenopausal women with advanced breast carcinoma: results of a survival update based on a combined analysis of data from two mature phase III trials. Arimidex Study Group. Cancer 83 1142-1152.
    • (1998) Cancer , vol.83 , pp. 1142-1152
    • Buzdar, A.U.1    Jonat, W.2    Howell, A.3    Jones, S.E.4    Blomqvist, C.P.5    Vogel, C.L.6    Eiermann, W.7    Wolter, J.M.8    Steinberg, M.9    Webster, A.10    Lee, D.11
  • 7
    • 0029833720 scopus 로고    scopus 로고
    • The effect of tamoxifen and hormone replacement therapy on serum cholesterol, bone mineral density and coagulation factors in healthy postmenopausal women participating in a randomised, controlled tamoxifen prevention study
    • Chang J, Powles TJ, Ashley SE, Gregory RK, Tidy VA, Treleaven JG & Singh R 1996 The effect of tamoxifen and hormone replacement therapy on serum cholesterol, bone mineral density and coagulation factors in healthy postmenopausal women participating in a randomised, controlled tamoxifen prevention study. Annals of Oncology 7 671-675.
    • (1996) Annals of Oncology , vol.7 , pp. 671-675
    • Chang, J.1    Powles, T.J.2    Ashley, S.E.3    Gregory, R.K.4    Tidy, V.A.5    Treleaven, J.G.6    Singh, R.7
  • 8
    • 0027768899 scopus 로고
    • The antiestrogen ICI 182,780 disrupts estrogen receptor nucleocytoplasmic shuttling
    • Dauvois S, White R & Parker MG 1993 The antiestrogen ICI 182,780 disrupts estrogen receptor nucleocytoplasmic shuttling. Journal of Cell Science 106 1377-1388.
    • (1993) Journal of Cell Science , vol.106 , pp. 1377-1388
    • Dauvois, S.1    White, R.2    Parker, M.G.3
  • 10
    • 0034926060 scopus 로고    scopus 로고
    • Selective estrogen receptor modulation: The search for an ideal hormonal therapy for breast cancer
    • Dhingra K 2001 Selective estrogen receptor modulation: the search for an ideal hormonal therapy for breast cancer. Cancer Investigation 19 649-659.
    • (2001) Cancer Investigation , vol.19 , pp. 649-659
    • Dhingra, K.1
  • 12
    • 0034122595 scopus 로고    scopus 로고
    • Antiproliferative effects of idoxifene in a placebocontrolled trial in primary human breast cancer
    • Dowsett M, Dixon JM, Horgan K, Salter J, Hills M & Harvey E 2000 Antiproliferative effects of idoxifene in a placebocontrolled trial in primary human breast cancer. Clinical Cancer Research 6 2260-2267.
    • (2000) Clinical Cancer Research , vol.6 , pp. 2260-2267
    • Dowsett, M.1    Dixon, J.M.2    Horgan, K.3    Salter, J.4    Hills, M.5    Harvey, E.6
  • 13
    • 0026776174 scopus 로고
    • Antiuterotrophic effects of a pure antiestrogen, ICI 182,780: Magnetic resonance imaging of the uterus in ovariectomized monkeys
    • Dukes M, Miller D, Wakeling AE & Waterton JC 1992 Antiuterotrophic effects of a pure antiestrogen, ICI 182,780: magnetic resonance imaging of the uterus in ovariectomized monkeys. Journal of Endocrinology 135 239-247.
    • (1992) Journal of Endocrinology , vol.135 , pp. 239-247
    • Dukes, M.1    Miller, D.2    Wakeling, A.E.3    Waterton, J.C.4
  • 14
    • 0347509651 scopus 로고    scopus 로고
    • ICI 182,780 ('Faslodex') 250 mg monthly intramuscular (i.m.) injection shows consistent PK profile when given as either 1 × 5 ml or 2 ± 2.5 ml injections in postmenopausal women with advanced breast cancer (ABC)
    • abstract 2025
    • Erikstein B, Robertson JFR, Osborne KC, Pippen J & Harrison M 2001 ICI 182,780 ('Faslodex') 250 mg monthly intramuscular (i.m.) injection shows consistent PK profile when given as either 1 × 5 ml or 2 ± 2.5 ml injections in postmenopausal women with advanced breast cancer (ABC). Presented at 37th American Society of Clinical Oncology Annual Meeting, 2001, San Francisco (abstract 2025).
    • (2001) 37th American Society of Clinical Oncology Annual Meeting, 2001, San Francisco
    • Erikstein, B.1    Robertson, J.F.R.2    Osborne, K.C.3    Pippen, J.4    Harrison, M.5
  • 15
    • 0028149773 scopus 로고
    • Megestrol acetate in advanced breast carcinoma
    • Espie M 1994 Megestrol acetate in advanced breast carcinoma. Oncology 51 (Suppl 1) 8-12.
    • (1994) Oncology , vol.51 , Issue.SUPPL. 1 , pp. 8-12
    • Espie, M.1
  • 16
    • 0025084510 scopus 로고
    • Inhibition of estrogen receptor-DNA binding by the 'pure' antiestrogen ICI 164,384 appears to be mediated by impaired receptor dimerization
    • Fawell SE, White R, Hoare S, Sydenham M, Page M & Parker MG 1990 Inhibition of estrogen receptor-DNA binding by the 'pure' antiestrogen ICI 164,384 appears to be mediated by impaired receptor dimerization. PNAS 87 6883-6887.
    • (1990) PNAS , vol.87 , pp. 6883-6887
    • Fawell, S.E.1    White, R.2    Hoare, S.3    Sydenham, M.4    Page, M.5    Parker, M.G.6
  • 20
    • 0027433430 scopus 로고
    • Randomized comparison of the effects of tamoxifen, megestrol acetate, or tamoxifen plus megestrol acetate on treatment response and survival in patients with metastatic breast cancer
    • Gill PG, Gebski V, Snyder R, Burns I, Levi J, Byrne M & Coates A 1993 Randomized comparison of the effects of tamoxifen, megestrol acetate, or tamoxifen plus megestrol acetate on treatment response and survival in patients with metastatic breast cancer. Annals of Oncology 4 741-744.
    • (1993) Annals of Oncology , vol.4 , pp. 741-744
    • Gill, P.G.1    Gebski, V.2    Snyder, R.3    Burns, I.4    Levi, J.5    Byrne, M.6    Coates, A.7
  • 24
    • 0034663421 scopus 로고    scopus 로고
    • ICI 182,780 (Faslodex): Development of a novel, 'pure' antiestrogen
    • Howell A, Osborne CK, Morris C & Wakeling AE 2000 ICI 182,780 (Faslodex): development of a novel, 'pure' antiestrogen. Cancer 89 817-825.
    • (2000) Cancer , vol.89 , pp. 817-825
    • Howell, A.1    Osborne, C.K.2    Morris, C.3    Wakeling, A.E.4
  • 25
    • 0001213189 scopus 로고    scopus 로고
    • ICI 182,780 (Faslodex™) versus anastrozole (ArimidexTM) for the treatment of advanced breast cancer in postmenopausal women - Prospective combined analysis of two multicentre trials
    • abstract 550
    • Howell A, Osborne CK, Robertson JFR, Jones SE, Mauriac L, Ellis M, Come S, Vergote I, Buzdar A, Gerther S 2001 ICI 182,780 (Faslodex™) versus anastrozole (ArimidexTM) for the treatment of advanced breast cancer in postmenopausal women - prospective combined analysis of two multicentre trials. European Journal of Cancer 37 151 (abstract 550).
    • (2001) European Journal of Cancer , vol.37 , pp. 151
    • Howell, A.1    Osborne, C.K.2    Robertson, J.F.R.3    Jones, S.E.4    Mauriac, L.5    Ellis, M.6    Come, S.7    Vergote, I.8    Buzdar, A.9    Gerther, S.10
  • 28
    • 0035344623 scopus 로고    scopus 로고
    • Systemic treatment of metastatic breast cancer
    • Johnston SR 2001 Systemic treatment of metastatic breast cancer. Hospital Medicine 62 289-295.
    • (2001) Hospital Medicine , vol.62 , pp. 289-295
    • Johnston, S.R.1
  • 30
    • 0034490211 scopus 로고    scopus 로고
    • Cross-resistance of triphenylethylene-type antiestrogens but not ICI 182,780 in tamoxifen-stimulated breast tumors grown in athymic mice
    • Lee ES, Schafer JM, Yao K, England G, O'Regan RM, De Los Reyes A & Jordan VC 2000 Cross-resistance of triphenylethylene-type antiestrogens but not ICI 182,780 in tamoxifen-stimulated breast tumors grown in athymic mice. Clinical Cancer Research 6 4893-4899.
    • (2000) Clinical Cancer Research , vol.6 , pp. 4893-4899
    • Lee, E.S.1    Schafer, J.M.2    Yao, K.3    England, G.4    O'Regan, R.M.5    De Los Reyes, A.6    Jordan, V.C.7
  • 31
    • 0034987631 scopus 로고    scopus 로고
    • Enhanced epidermal growth factor receptor signaling in MCF-7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182,780 (Faslodex)
    • McClelland RA, Barrow D, Madden TA, Dutkowski CM, Pamment J, Knowlden JM, Gee JM & Nicholson RI 2001 Enhanced epidermal growth factor receptor signaling in MCF-7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182,780 (Faslodex). Endocrinology 142 2776-2788.
    • (2001) Endocrinology , vol.142 , pp. 2776-2788
    • McClelland, R.A.1    Barrow, D.2    Madden, T.A.3    Dutkowski, C.M.4    Pamment, J.5    Knowlden, J.M.6    Gee, J.M.7    Nicholson, R.I.8
  • 32
    • 0346879172 scopus 로고    scopus 로고
    • Fulvestrant (Faslodex') versus anastrozole for the treatment of advanced breast cancer in a subgroup of postmenopausal women with visceral metastases: Combined results from two multicenter trials
    • bstract 215
    • Mauriac L, Pippen JE, Quaresma Albano J, Gertler SZ & Osborne CK (for the Faslodex Trial 0020 and 0021 Investigators) 2002 Fulvestrant (Faslodex') versus anastrozole for the treatment of advanced breast cancer in a subgroup of postmenopausal women with visceral metastases: combined results from two multicenter trials. European Journal of Cancer 38 (Suppl 3) S96 (abstract 215).
    • (2002) European Journal of Cancer , vol.38 , Issue.SUPPL. 3
    • Mauriac, L.1    Pippen, J.E.2    Quaresma Albano, J.3    Gertler, S.Z.4    Osborne, C.K.5
  • 33
    • 0002149652 scopus 로고    scopus 로고
    • Antiaromatase agents: Preclinical data and neoadjuvant therapy
    • Miller WR & Dixon JM 2000 Antiaromatase agents: preclinical data and neoadjuvant therapy. Clinical Breast Cancer 1 (Suppl 1) S9-S14.
    • (2000) Clinical Breast Cancer , vol.1 , Issue.SUPPL. 1
    • Miller, W.R.1    Dixon, J.M.2
  • 35
    • 0034669484 scopus 로고    scopus 로고
    • Anastrozole is superior to tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: Results of a North American multicenter randomized trial
    • Arimidex Study Group
    • Nabholtz JM, Buzdar A, Pollak M, Harwin W, Burton G, Mangalik A, Steinberg M, Webster A & von Euler M 2000 Anastrozole is superior to tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: results of a North American multicenter randomized trial. Arimidex Study Group. Journal of Clinical Oncology 18 3758-3767.
    • (2000) Journal of Clinical Oncology , vol.18 , pp. 3758-3767
    • Nabholtz, J.M.1    Buzdar, A.2    Pollak, M.3    Harwin, W.4    Burton, G.5    Mangalik, A.6    Steinberg, M.7    Webster, A.8    Von Euler, M.9
  • 38
  • 39
    • 0346248819 scopus 로고    scopus 로고
    • Greater duration of response in postmenopausal patients receiving fulvestrant ('faslodex') compared with those receiving anastrozole
    • abstract 160
    • Parker LM & Webster A 2002 Greater duration of response in postmenopausal patients receiving fulvestrant ('faslodex') compared with those receiving anastrozole. Presented at 38th American Society of Clinical Oncology Annual Meeting, 2002, Orlando, Florida (abstract 160).
    • (2002) 38th American Society of Clinical Oncology Annual Meeting, 2002, Orlando, Florida
    • Parker, L.M.1    Webster, A.2
  • 40
    • 0001868027 scopus 로고    scopus 로고
    • Fulvestrant ('Faslodex') as hormonal treatment in postmenopausal patients with advanced breast cancer (ABC) progressing after treatment with tamoxifen and non-steroidal aromatase inhibitors: An ongoing phase II SAKK trial
    • For the Swiss Group for Clinical Cancer Research for Clinical Cancer Research (SAKK) abstract P172
    • Perey L, Thürlimann B, Hawle H, Bonnefoi H, Aebi S, Pagani O, Goldhirsch A & Dietrich D 2002 For the Swiss Group for Clinical Cancer Research for Clinical Cancer Research (SAKK). Fulvestrant ('Faslodex') as hormonal treatment in postmenopausal patients with advanced breast cancer (ABC) progressing after treatment with tamoxifen and non-steroidal aromatase inhibitors: an ongoing phase II SAKK trial. Annals of Oncology 13 (Suppl 5) S 48 (abstract P172).
    • (2002) Annals of Oncology , vol.13 , Issue.SUPPL. 5
    • Perey, L.1    Thürlimann, B.2    Hawle, H.3    Bonnefoi, H.4    Aebi, S.5    Pagani, O.6    Goldhirsch, A.7    Dietrich, D.8
  • 41
    • 0030070093 scopus 로고    scopus 로고
    • Effect of tamoxifen on bone mineral density measured by dual-energy X-ray absorptiometry in healthy premenopausal and postmenopausal women
    • Powles TJ, Hickish T, Kanis JA, Tidy A & Ashley S 1996 Effect of tamoxifen on bone mineral density measured by dual-energy X-ray absorptiometry in healthy premenopausal and postmenopausal women. Journal of Clinical Oncology 14 78-84.
    • (1996) Journal of Clinical Oncology , vol.14 , pp. 78-84
    • Powles, T.J.1    Hickish, T.2    Kanis, J.A.3    Tidy, A.4    Ashley, S.5
  • 44
    • 0002212879 scopus 로고    scopus 로고
    • A comparison of the single-dose pharmacokinetics of ICI 182,780 ('Faslodex') 250 mg when given as either a one × 5-ml intramuscular injection or two × 2.5-ml injections in postmenopausal women with advanced breast cancer
    • abstract 172
    • Robertson JFR 2000 A comparison of the single-dose pharmacokinetics of ICI 182,780 ('Faslodex') 250 mg when given as either a one × 5-ml intramuscular injection or two × 2.5-ml injections in postmenopausal women with advanced breast cancer. Breast Cancer Research and Treatment 64 53 (abstract 172).
    • (2000) Breast Cancer Research and Treatment , vol.64 , pp. 53
    • Robertson, J.F.R.1
  • 46
    • 0035884408 scopus 로고    scopus 로고
    • Comparison of the short-term biological effects of 7alpha-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]estra-1,3,5, (10)-triene-3,17beta-diol (Faslodex) versus tamoxifen in postmenopausal women with primary breast cancer
    • Robertson JF, Nicholson RI, Bundred NJ, Anderson E, Rayter Z, Dowsett M, Fox JN, Gee JM, Webster A, Wakeling AE, Morris C & Dixon M 2001 Comparison of the short-term biological effects of 7alpha-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]estra-1,3,5, (10)-triene-3,17beta-diol (Faslodex) versus tamoxifen in postmenopausal women with primary breast cancer. Cancer Research 6 6739-6746.
    • (2001) Cancer Research , vol.6 , pp. 6739-6746
    • Robertson, J.F.1    Nicholson, R.I.2    Bundred, N.J.3    Anderson, E.4    Rayter, Z.5    Dowsett, M.6    Fox, J.N.7    Gee, J.M.8    Webster, A.9    Wakeling, A.E.10    Morris, C.11    Dixon, M.12
  • 47
    • 0013443921 scopus 로고    scopus 로고
    • Fulvestrant versus tamoxifen for the first-line treatment of advanced breast cancer (ABC) in postmenopausal women
    • abstract 1640
    • Robertson JFR, Howell A, Abram P, Lichinitser MR & Elledge R 2002 Fulvestrant versus tamoxifen for the first-line treatment of advanced breast cancer (ABC) in postmenopausal women. Annals of Oncology 13 (Suppl 5) 46 (abstract 1640).
    • (2002) Annals of Oncology , vol.13 , Issue.SUPPL. 5 , pp. 46
    • Robertson, J.F.R.1    Howell, A.2    Abram, P.3    Lichinitser, M.R.4    Elledge, R.5
  • 48
    • 0037157603 scopus 로고    scopus 로고
    • Arimidex, tamoxifen alone or in combination. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: First results of the ATAC randomised trial
    • The ATAC Trialists' Group 2002 Arimidex, tamoxifen alone or in combination. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial. Lancet 359 2131-2139.
    • (2002) Lancet , vol.359 , pp. 2131-2139
  • 49
    • 0035211987 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators: Mechanism of action and clinical experience. Focus on raloxifene
    • Thiebaud D & Secrest RJ 2001 Selective estrogen receptor modulators: mechanism of action and clinical experience. Focus on raloxifene. Reproduction, Fertility and Development 13 331-336.
    • (2001) Reproduction, Fertility and Development , vol.13 , pp. 331-336
    • Thiebaud, D.1    Secrest, R.J.2
  • 50
    • 4243761728 scopus 로고    scopus 로고
    • Evidence of continued sensitivity to endocrine agents in postmenopausal women with advanced breast cancer progressing on fulvestrant ('Faslodex') treatment
    • abstract 216
    • Vergote I 2002 Evidence of continued sensitivity to endocrine agents in postmenopausal women with advanced breast cancer progressing on fulvestrant ('Faslodex') treatment. European Journal of Cancer 38 (Suppl 3) S96 (abstract 216).
    • (2002) European Journal of Cancer , vol.38 , Issue.SUPPL. 3
    • Vergote, I.1
  • 51
    • 0034023827 scopus 로고    scopus 로고
    • Similarities and distinctions in the mode of action of different classes of antiestrogens
    • Wakeling AE 2000 Similarities and distinctions in the mode of action of different classes of antiestrogens. Endocrine-Related Cancer 7 17-28.
    • (2000) Endocrine-Related Cancer , vol.7 , pp. 17-28
    • Wakeling, A.E.1
  • 53
    • 0026395885 scopus 로고
    • A potent specific pure antiestrogen with clinical potential
    • Wakeling AE, Dukes M & Bowler J 1991 A potent specific pure antiestrogen with clinical potential. Cancer Research 5 3867-3873.
    • (1991) Cancer Research , vol.5 , pp. 3867-3873
    • Wakeling, A.E.1    Dukes, M.2    Bowler, J.3
  • 54
    • 0027758638 scopus 로고
    • McGuire Memorial Symposium. Drug resistance to tamoxifen during breast cancer therapy
    • Wolf DM, Jordan VC & William L 1993 McGuire Memorial Symposium. Drug resistance to tamoxifen during breast cancer therapy. Breast Cancer Research and Treatment 27 27-40.
    • (1993) Breast Cancer Research and Treatment , vol.27 , pp. 27-40
    • Wolf, D.M.1    Jordan, V.C.2    William, L.3


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