-
1
-
-
0023798520
-
Inhibition of type II topoisomerase by fostriecin
-
Boritzki TJ, Wolfard TS, Besser JA, Jackson RC and Fry DW (1988) Inhibition of type II topoisomerase by fostriecin. Biochem Pharmacol 37:4063-4068.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 4063-4068
-
-
Boritzki, T.J.1
Wolfard, T.S.2
Besser, J.A.3
Jackson, R.C.4
Fry, D.W.5
-
2
-
-
0027140482
-
Teniposide-resistant CEM cells, which express mutant topoisomerase IIa, when treated with non-complex-stabilizing inhibitors of the enzyme, display no cross-resistance and reveal aberrant functions of the mutant enzyme
-
Chen M and Beck WT (1993) Teniposide-resistant CEM cells, which express mutant topoisomerase IIa, when treated with non-complex-stabilizing inhibitors of the enzyme, display no cross-resistance and reveal aberrant functions of the mutant enzyme. Cancer Res 53:5946-5953.
-
(1993)
Cancer Res
, vol.53
, pp. 5946-5953
-
-
Chen, M.1
Beck, W.T.2
-
3
-
-
0028933380
-
Differences in inhibition of chromosome separation and G2 arrest bv DNA topoisomerase II inhibitors merbarone and VM-26
-
Chen M and Beck WT (1995) Differences in inhibition of chromosome separation and G2 arrest bv DNA topoisomerase II inhibitors merbarone and VM-26. Cancer Res 55:1509-1516.
-
(1995)
Cancer Res
, vol.55
, pp. 1509-1516
-
-
Chen, M.1
Beck, W.T.2
-
4
-
-
0029753773
-
The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet c and gamma radiation. Duration of JNK activation may determine cell death and proliferation
-
Chen Y-R, Wang X, Templeton D, Davis RJ and Tan T-H (1996) The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation. J Biol Chem 271:31929-31936.
-
(1996)
J Biol Chem
, vol.271
, pp. 31929-31936
-
-
Chen, Y.-R.1
Wang, X.2
Templeton, D.3
Davis, R.J.4
Tan, T.-H.5
-
5
-
-
0030788405
-
Activation of STAT signaling pathway can cause expression of caspase 1 and apoptosis
-
Chin YE, Kitagawa M, Kuida K, Flavell RA and Fu XY (1997) Activation of STAT signaling pathway can cause expression of caspase 1 and apoptosis. Mol Cell Biol 17:5328-5337.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 5328-5337
-
-
Chin, Y.E.1
Kitagawa, M.2
Kuida, K.3
Flavell, R.A.4
Fu, X.Y.5
-
6
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidine thiocyanate-phenol-chloroform extraction
-
Chomezynski P and Sacchi N (1987) Single-step method of RNA isolation by acid guanidine thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
-
(1987)
Anal Biochem
, vol.162
, pp. 156-159
-
-
Chomezynski, P.1
Sacchi, N.2
-
7
-
-
0030931876
-
Caspases: The executioners of apoptosis
-
Cohen GM (1997) Caspases: The executioners of apoptosis. Biochem J 326:1-16.
-
(1997)
Biochem J
, vol.326
, pp. 1-16
-
-
Cohen, G.M.1
-
8
-
-
0026645859
-
Expression and involvement of c-fos and c-jun protooncogenes in programmed cell death induced by growth factor deprivation in lymphoid cell lines
-
Colotta F, Polentarutti N, Sironi M and Mantovani A (1992) Expression and involvement of c-fos and c-jun protooncogenes in programmed cell death induced by growth factor deprivation in lymphoid cell lines. J Biol Chem 267:18278-18283.
-
(1992)
J Biol Chem
, vol.267
, pp. 18278-18283
-
-
Colotta, F.1
Polentarutti, N.2
Sironi, M.3
Mantovani, A.4
-
9
-
-
0022357071
-
Initial mechanistic studies with merbarone
-
Cooney DA, Covey JM, Kay GJ, Dalal M, McMahon JB and Johns DG (1985) Initial mechanistic studies with merbarone. Biochem Pharmacol 34:3395-3398.
-
(1985)
Biochem Pharmacol
, vol.34
, pp. 3395-3398
-
-
Cooney, D.A.1
Covey, J.M.2
Kay, G.J.3
Dalal, M.4
McMahon, J.B.5
Johns, D.G.6
-
10
-
-
0028073283
-
MAP kinases: New jnk expands the group
-
Davis RJ (1994) MAP kinases: New JNK expands the group. Trends Biochem Sci 19:470-473.
-
(1994)
Trends Biochem Sci
, vol.19
, pp. 470-473
-
-
Davis, R.J.1
-
11
-
-
0029885419
-
Selective interaction of JNK protein kinase isoforms with transcription factors
-
Gupta S, Barrett T, Whitmarsh AJ, Cavanagh J, Sluss HK, Derijard B and Davis RJ (1996) Selective interaction of JNK protein kinase isoforms with transcription factors. EMBO J 15:2760-2770.
-
(1996)
EMBO J
, vol.15
, pp. 2760-2770
-
-
Gupta, S.1
Barrett, T.2
Whitmarsh, A.J.3
Cavanagh, J.4
Sluss, H.K.5
Derijard, B.6
Davis, R.J.7
-
12
-
-
0031959734
-
2-deoxyglucose inhibits chemotherapeutic drug-induced apoptosis in human monocytic leukemia U937 cells with inhibition of c-Jun N-terminal kinase 1/stress-activated protein kinase activation
-
Haga N, Naito M, Seimiya H, Tomida A, Dong J and Tsuruo T (1998) 2-deoxyglucose inhibits chemotherapeutic drug-induced apoptosis in human monocytic leukemia U937 cells with inhibition of c-Jun N-terminal kinase 1/stress-activated protein kinase activation. Int J Cancer 76:86-90.
-
(1998)
Int J Cancer
, vol.76
, pp. 86-90
-
-
Haga, N.1
Naito, M.2
Seimiya, H.3
Tomida, A.4
Dong, J.5
Tsuruo, T.6
-
13
-
-
0029012476
-
A c-jun dominant negative mutant protects sympathetic neurons against programmed cell death
-
Ham J, Babij C, Whitfield J, Pfarr CM, Lallemand D, Yaniv Y and Rubin LL (1995) A c-jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron 14:927-939.
-
(1995)
Neuron
, vol.14
, pp. 927-939
-
-
Ham, J.1
Babij, C.2
Whitfield, J.3
Pfarr, C.M.4
Lallemand, D.5
Yaniv, Y.6
Rubin, L.L.7
-
14
-
-
0032546783
-
ERICE, a novel FLICE-activatable caspase
-
Humke EW, Ni J and Dixit VM (1998) ERICE, a novel FLICE-activatable caspase. J Biol Chem 273:15702-15707.
-
(1998)
J Biol Chem
, vol.273
, pp. 15702-15707
-
-
Humke, E.W.1
Ni, J.2
Dixit, V.M.3
-
15
-
-
0026425654
-
Inhibition of intracellular topoisomerase II by antitumor bis(2,6-dioxopiperazine) derivatives: Mode of cell growth inhibition distinct from that of cleavable complex-forming type of inhibitors
-
Ishida R, Miki T, Narita T, Yui R, Sato M, Utsumi KR, Tanabe K and Andoh T (1991) Inhibition of intracellular topoisomerase II by antitumor bis(2,6-dioxopiperazine) derivatives: Mode of cell growth inhibition distinct from that of cleavable complex-forming type of inhibitors. Cancer Res 51:4909-4916.
-
(1991)
Cancer Res
, vol.51
, pp. 4909-4916
-
-
Ishida, R.1
Miki, T.2
Narita, T.3
Yui, R.4
Sato, M.5
Utsumi, K.R.6
Tanabe, K.7
Andoh, T.8
-
16
-
-
0027194055
-
Different modes of anthracycline interaction with topoisomerase II. Separate structures critical for DNA cleavage and for overcoming topoisomerase II-related drug resistance
-
Jensen PB, Sorensen BS, Schested M, Demant EJ, Kjeldsen E, Friche E and Hansen HH (1993) Different modes of anthracycline interaction with topoisomerase II. Separate structures critical for DNA cleavage and for overcoming topoisomerase II-related drug resistance. Biochem Pharmacol 45:2025-2035.
-
(1993)
Biochem Pharmacol
, vol.45
, pp. 2025-2035
-
-
Jensen, P.B.1
Sorensen, B.S.2
Schested, M.3
Demant, E.J.4
Kjeldsen, E.5
Friche, E.6
Hansen, H.H.7
-
18
-
-
0028024165
-
Differences between drug-sensitive and resistant human leukemic CEM cells in c-jun expression, AP-1 DNA-binding activity, and formation of Jun/Fos family dimers, and their association with internucleosomal DNA ladders after treatment with VM-26
-
Kim R and Beck WT (1994) Differences between drug-sensitive and resistant human leukemic CEM cells in c-jun expression, AP-1 DNA-binding activity, and formation of Jun/Fos family dimers, and their association with internucleosomal DNA ladders after treatment with VM-26. Cancer Res 54:4958-4966.
-
(1994)
Cancer Res
, vol.54
, pp. 4958-4966
-
-
Kim, R.1
Beck, W.T.2
-
19
-
-
0029956641
-
Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice
-
Kuida K, Zheng TS, Songqing N, Kuan C, Yang D, Karasuyama H, Rakic P and Flavell RA (1996) Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature (London) 384:368-372.
-
(1996)
Nature (London)
, vol.384
, pp. 368-372
-
-
Kuida, K.1
Zheng, T.S.2
Songqing, N.3
Kuan, C.4
Yang, D.5
Karasuyama, H.6
Rakic, P.7
Flavell, R.A.8
-
20
-
-
0030013319
-
Characterization of novel human leukemic cell lines selected for resistance to merbarone, a catalytic inhibitor of DNA topoisomerase II
-
Kusumoto H, Rodgers QE, Boege F, Raimondi SC and Beck WT (1996) Characterization of novel human leukemic cell lines selected for resistance to merbarone, a catalytic inhibitor of DNA topoisomerase II. Cancer Res 56:2573-2583.
-
(1996)
Cancer Res
, vol.56
, pp. 2573-2583
-
-
Kusumoto, H.1
Rodgers, Q.E.2
Boege, F.3
Raimondi, S.C.4
Beck, W.T.5
-
21
-
-
0031016440
-
Lack of a role for Jun kinase and AP-1 in fas-induced apoptosis
-
Lenczowski JM, Lourdes D, Eder AM, King LB, Zacharchuk CM and Ashwell JD (1997) Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis. Mol Cell Biol 17:170-181.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 170-181
-
-
Lenczowski, J.M.1
Lourdes, D.2
Eder, A.M.3
King, L.B.4
Zacharchuk, C.M.5
Ashwell, J.D.6
-
22
-
-
0028943245
-
Identification of a dual specificity kinase that activates Jun kinases and p38-Mpk2
-
Lin A, Minden A, Martinetto H, Claret F-X, Lange-Carter C, Mercurio F, Johnson GL and Karin M (1995) Identification of a dual specificity kinase that activates Jun kinases and p38-Mpk2. Science 268:286-290.
-
(1995)
Science
, vol.268
, pp. 286-290
-
-
Lin, A.1
Minden, A.2
Martinetto, H.3
Claret, F.-X.4
Lange-Carter, C.5
Mercurio, F.6
Johnson, G.L.7
Karin, M.8
-
23
-
-
0030298294
-
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappa B activation prevents cell death
-
Liu Z-G, Hsu H, Goeddel DV and Karin M (1996) Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappa B activation prevents cell death. Cell 87:565-576.
-
(1996)
Cell
, vol.87
, pp. 565-576
-
-
Liu, Z.-G.1
Hsu, H.2
Goeddel, D.V.3
Karin, M.4
-
24
-
-
0028990358
-
Aspartate-based inhibition of interleukin-1b converting enzyme prevents antitumor agent-induced apoptosis in human myeloid leukemia U937 cells
-
Mashima T, Naito M, Kataoka S, Kawai H and Tsuruo T (1995) Aspartate-based inhibition of interleukin-1b converting enzyme prevents antitumor agent-induced apoptosis in human myeloid leukemia U937 cells. Biochem Biophys Res Commun 209:907-915.
-
(1995)
Biochem Biophys Res Commun
, vol.209
, pp. 907-915
-
-
Mashima, T.1
Naito, M.2
Kataoka, S.3
Kawai, H.4
Tsuruo, T.5
-
25
-
-
0033054992
-
DNA damage signals induction of fas ligand in tumor cells
-
Mo Y-Y and Beck WT (1999) DNA damage signals induction of Fas ligand in tumor cells. Mol Pharmacol 55:216-222.
-
(1999)
Mol Pharmacol
, vol.55
, pp. 216-222
-
-
Mo, Y.-Y.1
Beck, W.T.2
-
26
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
-
Nicholson DW, All A, Thornberry AA, Vaillancourt JP, Diang CK, Gallant M, Gareau Y, Griffin PR, Labelle M, Lazebuik YA, Munday NA, Raju SM, Smulson ME, Yamin TT, Yu VL and Miller DK (1995) Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature (London) 376: 37-43.
-
(1995)
Nature (London)
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
All, A.2
Thornberry, A.A.3
Vaillancourt, J.P.4
Diang, C.K.5
Gallant, M.6
Gareau, Y.7
Griffin, P.R.8
Labelle, M.9
Lazebuik, Y.A.10
Munday, N.A.11
Raju, S.M.12
Smulson, M.E.13
Yamin, T.T.14
Yu, V.L.15
Miller, D.K.16
-
27
-
-
0029944106
-
Antitopoisomerase drug action and resistance
-
Nitiss JL and Beck WT (1996) Antitopoisomerase drug action and resistance. Eur J Cancer 42A:958-966.
-
(1996)
Eur J Cancer
, vol.42 A
, pp. 958-966
-
-
Nitiss, J.L.1
Beck, W.T.2
-
28
-
-
0028345406
-
Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp
-
Roca J, Ishida R, Berger JM, Andoh T and Wang JC (1994) Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp. Proc Natl Acad Sci USA 91:1781-1785.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 1781-1785
-
-
Roca, J.1
Ishida, R.2
Berger, J.M.3
Andoh, T.4
Wang, J.C.5
-
29
-
-
0030614914
-
2-terminal kinase-mediated activation of interleukin-1β converting enzyme/CED-3-like protease during anticancer drug-induced apoptosis
-
2-terminal kinase-mediated activation of Interleukin-1β Converting Enzyme/CED-3-like protease during anticancer drug-induced apoptosis. J Biol Chem 272:4631-4636.
-
(1997)
J Biol Chem
, vol.272
, pp. 4631-4636
-
-
Seimiya, H.1
Mashima, T.2
Toho, M.3
Tsuruo, T.4
-
30
-
-
0029144891
-
An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes
-
Tamura T, Ishihara M, Lamphier MS, Tanaka N, Oishi I, Aizawa S, Matsuyama T, Mak T, Taki S and Taniguchi T (1995) An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes. Nature (London)376:596-599.
-
(1995)
Nature (London)
, vol.376
, pp. 596-599
-
-
Tamura, T.1
Ishihara, M.2
Lamphier, M.S.3
Tanaka, N.4
Oishi, I.5
Aizawa, S.6
Matsuyama, T.7
Mak, T.8
Taki, S.9
Taniguchi, T.10
-
31
-
-
0026425619
-
Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives
-
Tanabe K, Ikegami Y, Ishida R and Andoh T (1991) Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives. Cancer Res 51:4903-4908.
-
(1991)
Cancer Res
, vol.51
, pp. 4903-4908
-
-
Tanabe, K.1
Ikegami, Y.2
Ishida, R.3
Andoh, T.4
-
32
-
-
0028990125
-
Yama/CPP32β, a mammalian homolog for CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
-
Tewari M, Quan LT, O'Rourke K, Desnoyers S, Zeng, Z, Beidler DR, Poirer GG, Salvesen GS and Dixit VM (1995) Yama/CPP32β, a mammalian homolog for CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 81:801-809.
-
(1995)
Cell
, vol.81
, pp. 801-809
-
-
Tewari, M.1
Quan, L.T.2
O'Rourke, K.3
Desnoyers, S.4
Zeng, Z.5
Beidler, D.R.6
Poirer, G.G.7
Salvesen, G.S.8
Dixit, V.M.9
-
33
-
-
0030838164
-
The caspase family of cysteine proteases
-
Thornberry NA (1997) The caspase family of cysteine proteases. Br Med Bull 53: 478-490.
-
(1997)
Br Med Bull
, vol.53
, pp. 478-490
-
-
Thornberry, N.A.1
-
34
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1-beta processing in monocytes
-
Thornberry NA, Bull HG, Calaycay JR, Chapman KT, Howard AD, Kostura MJ, Miller DK, Molineaux SM, Weidner JR and Aunins J (1992) A novel heterodimeric cysteine protease is required for interleukin-1-beta processing in monocytes. Nature (London) 356:768-774.
-
(1992)
Nature (London)
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
Bull, H.G.2
Calaycay, J.R.3
Chapman, K.T.4
Howard, A.D.5
Kostura, M.J.6
Miller, D.K.7
Molineaux, S.M.8
Weidner, J.R.9
Aunins, J.10
-
35
-
-
0028986623
-
Interleukin-1β converting enzyme: A novel cystein protease required for IL-1β production and implicated in programmed cell death
-
Thornberry NA and Molineaux SM (1995) Interleukin-1β converting enzyme: A novel cystein protease required for IL-1β production and implicated in programmed cell death. Protein Sci 4:3-12.
-
(1995)
Protein Sci
, vol.4
, pp. 3-12
-
-
Thornberry, N.A.1
Molineaux, S.M.2
-
36
-
-
0030984490
-
PARP is important for genomic stability but dispensable in apoptosis
-
Wang Z-Q, Stingl L, Morrison C, Jantsch M, Los M, Schulze-Osthoff K and Wagner EF (1997) PARP is important for genomic stability but dispensable in apoptosis. Genes & Dev 11:2347-2358.
-
(1997)
Genes & Dev
, vol.11
, pp. 2347-2358
-
-
Wang, Z.-Q.1
Stingl, L.2
Morrison, C.3
Jantsch, M.4
Los, M.5
Schulze-Osthoff, K.6
Wagner, E.F.7
-
37
-
-
0030046508
-
Life, death and the pursuit of apoptosis
-
White E (1996) Life, death and the pursuit of apoptosis. Genes & Dev 10:1-15.
-
(1996)
Genes & Dev
, vol.10
, pp. 1-15
-
-
White, E.1
-
38
-
-
0030829777
-
Apoptosis: An overview
-
Wyllie AH (1997) Apoptosis: An overview. Br Med Bull 53:451-465.
-
(1997)
Br Med Bull
, vol.53
, pp. 451-465
-
-
Wyllie, A.H.1
-
39
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia Z, Dickens M, Raingeaud J, Davis RJ and Greenberg ME (1995) Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270:1326-1331.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
40
-
-
0030134173
-
The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat
-
Zanke BW, Boudreau K, Rubie E, Winnett E, Tibbles LA, Zon L, Kyriakis J, Liu F-F and Woodgett JR (1996) The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat. Curr Biol 6:606-613.
-
(1996)
Curr Biol
, vol.6
, pp. 606-613
-
-
Zanke, B.W.1
Boudreau, K.2
Rubie, E.3
Winnett, E.4
Tibbles, L.A.5
Zon, L.6
Kyriakis, J.7
Liu, F.-F.8
Woodgett, J.R.9
|