5-Methyltetrahydrofolate and tetrahydrobiopterin can modulate electrotonically mediated endothelium-dependent vascular relaxation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 19, 2005, Pages 7008-7013

  Griffith, Tudor M ^a   Chaytor, Andrew T ^a   Bakker, Linda M ^a   Edwards, David H ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Connexin; Endothelium derived hyperpolarizing factor; Folic acid; Gap junction; Methotrexate

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; 5 METHYLTETRAHYDROFOLIC ACID; CATALASE; CONNEXIN 37; CONNEXIN 40; CYCLOPIAZONIC ACID; DIHYDROBIOPTERIN; FOLIC ACID; GAP 26 PROTEIN; GAP JUNCTION PROTEIN; HYDROGEN PEROXIDE; METHOTREXATE; NITRIC OXIDE; PHENYLEPHRINE; TETRAHYDROBIOPTERIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTERY INTIMA; ARTERY MEDIA; ARTERY WALL; ARTICLE; DRUG ANTAGONISM; DRUG MECHANISM; DRUG POTENTIATION; ELECTROPHYSIOLOGY; GAP JUNCTION; HYPERPOLARIZATION; ILIAC ARTERY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; VASCULAR ENDOTHELIUM; VASODILATATION;

ANIMALS; ANTIOXIDANTS; AORTA; AORTIC VALVE; BIOPTERIN; BORON COMPOUNDS; CALCIUM; CONNEXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRODES; ELECTRONS; ELECTROPHYSIOLOGY; ENDOTHELIUM, VASCULAR; FOLIC ACID; GAP JUNCTIONS; HEMOGLOBINS; ILIAC ARTERY; INDOLES; MALE; MEMBRANE POTENTIALS; MUSCLE, SMOOTH; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXIDANTS; RABBITS; SIGNAL TRANSDUCTION; TETRAHYDROFOLATES;

ORYCTOLAGUS CUNICULUS;

EID: 18744416561     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0408919102     Document Type: Article

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