The molecular perspective: Methotrexate

Stem Cells

Volumn 17, Issue 5, 1999, Pages 314-315

  Goodsell, D S ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPTERIN; BINDING PROTEIN; DIHYDROFOLATE REDUCTASE; METHOTREXATE; PURINE NUCLEOTIDE; PYRIMIDINE NUCLEOTIDE; THYMIDYLATE SYNTHASE;

CANCER CELL; CELL GROWTH; CHEMOTHERAPY; DNA BINDING; DNA SYNTHESIS; HUMAN; HUMAN CELL; MOLECULAR BIOLOGY; SHORT SURVEY;

EID: 0032696157     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.170314     Document Type: Short Survey

References (2)

1. Davies JF, Delcamp TJ, Prendergast NJ, et al. Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5‐deazafolate. Biochem 1990 ; 29: 9467–9479.
2. Allegra CJ, Grem JL. Antimetabolites in Cancer, Principles and Practice of Oncology. Lippincott‐Raven Publishers: Philadelphia, 1997 ; 1: 432–452.