Preparation of 2-pyridone-containing tricyclic alkaloid derivatives as potential inhibitors of tumor cell proliferation by regioselective intramolecular N- and C-acylation of 2-pyridone

Chemical and Pharmaceutical Bulletin

Volumn 53, Issue 1, 2005, Pages 67-71

  Wang, Shaozhong ^a   Cao, Liya ^a   Shi, Haijian ^a   Dong, Yanmei ^a   Sun, Jianwei ^a   Hu, Yuefei ^b  

^a NANJING UNIVERSITY   (China)

^b TSINGHUA UNIVERSITY   (China)

Author keywords

2 pyridone; Intramolecular C acylation; Intramolecular N acylation; Synthesis; Tricyclic alkaloid

Indexed keywords

1 METHYL 1H INDENO[1,2 B]PYRIDINE 2,5 DIONE DERIVATIVE; 2 PYRIDONE DERIVATIVE; ALKALOID DERIVATIVE; PYRIDO[2,1 A]ISOINDOLE 4,6 DIONE DERIVATIVE; UNCLASSIFIED DRUG; 2 HYDROXYPYRIDINE; 2-HYDROXYPYRIDINE; ALKALOID; ANTINEOPLASTIC AGENT; GROWTH INHIBITOR; PYRIDONE DERIVATIVE;

ACYLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; DRUG STRUCTURE; ISOMERISM; PHYSICAL CHEMISTRY; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; X RAY DIFFRACTION; DRUG EFFECT; STEREOISOMERISM; SYNTHESIS;

ACYLATION; ALKALOIDS; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; GROWTH INHIBITORS; PYRIDONES; STEREOISOMERISM;

EID: 18744409528     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.53.67     Document Type: Article

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