A study of the impact of freezing on the lyophilization of a concentrated formulation with a high fill depth

Pharmaceutical Development and Technology

Volumn 10, Issue 2, 2005, Pages 261-272

  Liu, Jinsong ^a   Viverette, Todd ^a   Virgin, Marlin ^a   Anderson, Mitch ^a   Dalal, Paresh ^a  

^a DSM Pharmaceutical Products   (Netherlands)

Author keywords

Cycle optimization; Freeze drying; Freezing process; Lyophilization; Product quality

Indexed keywords

CYCLODEXTRIN DERIVATIVE; IODINE DERIVATIVE; SIVER IODIDE; TERT BUTYL ALCOHOL; UNCLASSIFIED DRUG;

ARTICLE; COOLING; DRUG FORMULATION; FREEZE DRYING; FREEZING; PRIORITY JOURNAL; SCALE UP; VACUUM;

ALGORITHMS; BETA-CYCLODEXTRINS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CHEMISTRY, PHYSICAL; FREEZE DRYING; FREEZING; HUMIDITY; PARTICLE SIZE; TEMPERATURE;

EID: 18744408458     PISSN: 10837450     EISSN: None     Source Type: Journal    
DOI: 10.1081/PDT-200054452     Document Type: Article

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