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Volumn 269, Issue 23, 2002, Pages 5939-5949

Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions

Author keywords

Alzheimer's disease; Analytical ultracentrifugation; Apolipoprotein E; Lipid binding; Open conformation

Indexed keywords

APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; LIPID EMULSION;

EID: 18744407250     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2002.03319.x     Document Type: Article
Times cited : (37)

References (56)
  • 1
    • 0034830637 scopus 로고    scopus 로고
    • The interaction of human apolipoprotein C-I with submicellar phospholipid
    • Atcliffe, B.W., MacRaild, C.A., Gooley, P.R. & Howlett, G.J. (2001) The interaction of human apolipoprotein C-I with submicellar phospholipid. Eur. J. Biochem. 268, 2838-2846.
    • (2001) Eur. J. Biochem. , vol.268 , pp. 2838-2846
    • Atcliffe, B.W.1    MacRaild, C.A.2    Gooley, P.R.3    Howlett, G.J.4
  • 2
    • 0024495217 scopus 로고
    • Interaction of apoA-I and apoE-3 with triglyceride-phospholipid emulsions containing increasing cholesterol concentrations. Model of triglyceride-rich nascent and remnant lipoproteins
    • Derksen, A. & Small, D.M. (1989) Interaction of apoA-I and apoE-3 with triglyceride-phospholipid emulsions containing increasing cholesterol concentrations. Model of triglyceride-rich nascent and remnant lipoproteins. Biochemistry 28, 900-906.
    • (1989) Biochemistry , vol.28 , pp. 900-906
    • Derksen, A.1    Small, D.M.2
  • 3
    • 0034617305 scopus 로고    scopus 로고
    • Conformational reorganization of the four-helix bundle of human apolipoprotein E in binding to phospholipid
    • Lu, B., Morrow, J.A. & Weisgraber, K.H. (2000) Conformational reorganization of the four-helix bundle of human apolipoprotein E in binding to phospholipid. J. Biol. Chem. 275, 20775-20781.
    • (2000) J. Biol. Chem. , vol.275 , pp. 20775-20781
    • Lu, B.1    Morrow, J.A.2    Weisgraber, K.H.3
  • 4
    • 0034711265 scopus 로고    scopus 로고
    • Self-association of human apolipoprotein E3 and E4 in the presence and absence of phospholipid
    • Perugini, M.A., Schuck, P. & Howlett, G.J. (2000) Self-association of human apolipoprotein E3 and E4 in the presence and absence of phospholipid. J. Biol. Chem. 275, 36758-36765.
    • (2000) J. Biol. Chem. , vol.275 , pp. 36758-36765
    • Perugini, M.A.1    Schuck, P.2    Howlett, G.J.3
  • 5
    • 0034824483 scopus 로고    scopus 로고
    • Modulation of the lipid binding properties of the N-terminal domain of human apolipoprotein E3
    • Weers, P.M., Narayanaswami, V. & Ryan, R.O. (2001) Modulation of the lipid binding properties of the N-terminal domain of human apolipoprotein E3. Eur. J. Biochem. 268, 3728-3735.
    • (2001) Eur. J. Biochem. , vol.268 , pp. 3728-3735
    • Weers, P.M.1    Narayanaswami, V.2    Ryan, R.O.3
  • 6
    • 0022408782 scopus 로고
    • Behavior of human apolipoprotein E in aqueous solutions and at interfaces
    • Yokoyama, S., Kawai, Y., Tajima, S. & Yamamoto, A. (1985) Behavior of human apolipoprotein E in aqueous solutions and at interfaces. J. Biol. Chem. 260, 16375-16382.
    • (1985) J. Biol. Chem. , vol.260 , pp. 16375-16382
    • Yokoyama, S.1    Kawai, Y.2    Tajima, S.3    Yamamoto, A.4
  • 7
    • 0029766916 scopus 로고    scopus 로고
    • Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins
    • Dong, L.-M. & Weisgraber, K.H. (1996) Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins. J. Biol. Chem. 271, 19053-19057.
    • (1996) J. Biol. Chem. , vol.271 , pp. 19053-19057
    • Dong, L.-M.1    Weisgraber, K.H.2
  • 8
    • 0028092997 scopus 로고
    • Human apolipoprotein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3and E4 isoforms
    • Dong, L.-M., Wilson, C., Wardell, M.R., Simmons, T., Mahley, R.W., Weisgraber, K.H. & Agard, D.A. (1994) Human apolipo-protein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3and E4 isoforms. J. Biol. Chem. 269, 22358-22365.
    • (1994) J. Biol. Chem. , vol.269 , pp. 22358-22365
    • Dong, L.-M.1    Wilson, C.2    Wardell, M.R.3    Simmons, T.4    Mahley, R.W.5    Weisgraber, K.H.6    Agard, D.A.7
  • 9
    • 0033166082 scopus 로고    scopus 로고
    • Functional characterization of apolipoprotein E isoforms over-expressed in Escherichia coli
    • Morrow, J.A., Arnold, K.S. & Weisgraber, K.H. (1999) Functional characterization of apolipoprotein E isoforms over-expressed in Escherichia coli. Prot. Expr. Purif. 16, 224-230.
    • (1999) Prot. Expr. Purif. , vol.16 , pp. 224-230
    • Morrow, J.A.1    Arnold, K.S.2    Weisgraber, K.H.3
  • 10
    • 0025171570 scopus 로고
    • Apolipoprotein E distribution among human plasma lipoproteins: Role of the cysteine-arginine interchange at residue 112
    • Weisgraber, K.H. (1990) Apolipoprotein E distribution among human plasma lipoproteins: Role of the cysteine-arginine interchange at residue 112. J. Lipid Res. 31, 1503-1511.
    • (1990) J. Lipid Res. , vol.31 , pp. 1503-1511
    • Weisgraber, K.H.1
  • 11
    • 0021508760 scopus 로고
    • High density lipoprotein metabolism
    • Eisenberg, S. (1984) High density lipoprotein metabolism. J. Lipid Res. 25, 1017-1058.
    • (1984) J. Lipid Res. , vol.25 , pp. 1017-1058
    • Eisenberg, S.1
  • 12
    • 0024299370 scopus 로고
    • Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
    • Mahley, R.W. (1988) Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology. Science 240, 622-630.
    • (1988) Science , vol.240 , pp. 622-630
    • Mahley, R.W.1
  • 13
    • 0028303072 scopus 로고
    • Apolipoprotein E: Structure-function relationships
    • Weisgraber, K.H. (1994) Apolipoprotein E: Structure-function relationships. Adv. Prot. Chem. 45, 249-302.
    • (1994) Adv. Prot. Chem. , vol.45 , pp. 249-302
    • Weisgraber, K.H.1
  • 14
    • 0020490536 scopus 로고
    • Human apolipoprotein E. The complete amino acid sequence
    • Rall, S.C. Jr, Weisgraber, K.H. & Mahley, R.W. (1982) Human apolipoprotein E. The complete amino acid sequence. J. Biol. Chem. 257, 4171-4178.
    • (1982) J. Biol. Chem. , vol.257 , pp. 4171-4178
    • Rall S.C., Jr.1    Weisgraber, K.H.2    Mahley, R.W.3
  • 15
    • 0019783892 scopus 로고
    • Human E apoprotein heterogeneity. Cysteine-arginine interchanges in the amino acid sequence of the apo-E isoforms
    • Weisgraber, K.H., Rall, S.C. Jr & Mahley, R.W. (1981) Human E apoprotein heterogeneity. Cysteine-arginine interchanges in the amino acid sequence of the apo-E isoforms. J. Biol. Chem. 256, 9077-9083.
    • (1981) J. Biol. Chem. , vol.256 , pp. 9077-9083
    • Weisgraber, K.H.1    Rall S.C., Jr.2    Mahley, R.W.3
  • 16
    • 0016774441 scopus 로고
    • Familial hyperlipoproteinemia type III: Deficiency of a specific apolipoprotein (apo E-III) in the very-low-density lipoproteins
    • Utermann, G., Jaeschke, M. & Menzel, J. (1975) Familial hyperlipoproteinemia type III: deficiency of a specific apolipoprotein (apo E-III) in the very-low-density lipoproteins. FEBS Lett. 56, 352-355.
    • (1975) FEBS Lett. , vol.56 , pp. 352-355
    • Utermann, G.1    Jaeschke, M.2    Menzel, J.3
  • 17
    • 0034575124 scopus 로고    scopus 로고
    • Apolipoprotein E: Far more than a lipid transport protein
    • Mahley, R.W. & Rall, S.C. Jr (2000) Apolipoprotein E: Far more than a lipid transport protein. Ann. Rev. Genomics Hum. Genet. 1, 507-537.
    • (2000) Ann. Rev. Genomics Hum. Genet. , vol.1 , pp. 507-537
    • Mahley, R.W.1    Rall S.C., Jr.2
  • 18
    • 0023860891 scopus 로고
    • Apolipoprotein E polymorphism and atherosclerosis
    • Davignon, J., Gregg, R.E. & Sing, C.F. (1988) Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis 8, 1-21.
    • (1988) Arteriosclerosis , vol.8 , pp. 1-21
    • Davignon, J.1    Gregg, R.E.2    Sing, C.F.3
  • 21
    • 0034718456 scopus 로고    scopus 로고
    • Differences in stability among the human apolipoprotein E isoforms determined by the amino-terminal domain
    • Morrow, J.A., Segall, M.L., Lund-Katz, S., Phillips, M.C., Knapp, M., Rupp, B. & Weisgraber, K.H. (2000) Differences in stability among the human apolipoprotein E isoforms determined by the amino-terminal domain. Biochemistry 39, 11657-11666.
    • (2000) Biochemistry , vol.39 , pp. 11657-11666
    • Morrow, J.A.1    Segall, M.L.2    Lund-Katz, S.3    Phillips, M.C.4    Knapp, M.5    Rupp, B.6    Weisgraber, K.H.7
  • 22
    • 0025860481 scopus 로고
    • Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E
    • Wilson, C., Wardell, M.R., Weisgraber, K.H., Mahley, R.W. & Agard, D.A. (1991) Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E. Science 252, 1817-1822.
    • (1991) Science , vol.252 , pp. 1817-1822
    • Wilson, C.1    Wardell, M.R.2    Weisgraber, K.H.3    Mahley, R.W.4    Agard, D.A.5
  • 23
    • 0027186135 scopus 로고
    • Discrete carboxyl-terminal segments of apolipoprotein E mediate lipoprotein association and protein oligomerization
    • Westerlund, J.A. & Weisgraber, K.H. (1993) Discrete carboxyl-terminal segments of apolipoprotein E mediate lipoprotein association and protein oligomerization. J. Biol. Chem. 268, 15745-15750.
    • (1993) J. Biol. Chem. , vol.268 , pp. 15745-15750
    • Westerlund, J.A.1    Weisgraber, K.H.2
  • 24
    • 0034721777 scopus 로고    scopus 로고
    • The lipid-associated conformation of the low density lipoprotein receptor binding domain of human apolipoprotein E
    • Fisher, C.A., Narayanaswami, V. & Ryan, R.O. (2000) The lipid-associated conformation of the low density lipoprotein receptor binding domain of human apolipoprotein E. J. Biol. Chem. 275, 33601-33606.
    • (2000) J. Biol. Chem. , vol.275 , pp. 33601-33606
    • Fisher, C.A.1    Narayanaswami, V.2    Ryan, R.O.3
  • 26
    • 0035851137 scopus 로고    scopus 로고
    • Lipid association-induced N- and C-terminal domain reorganization in human apolipoprotein E3
    • Narayanaswami, V., Szeto, S.S.W. & Ryan, R.O. (2001) Lipid association-induced N- and C-terminal domain reorganization in human apolipoprotein E3. J. Biol. Chem. 276, 37853-37860.
    • (2001) J. Biol. Chem. , vol.276 , pp. 37853-37860
    • Narayanaswami, V.1    Szeto, S.S.W.2    Ryan, R.O.3
  • 27
    • 0033991858 scopus 로고    scopus 로고
    • Molecular basis of exchangeable apolipoprotein function
    • Narayanaswami, V. & Ryan, R.O. (2000) Molecular basis of exchangeable apolipoprotein function. Biochim. Biophys. Acta 1483, 15-36.
    • (2000) Biochim. Biophys. Acta , vol.1483 , pp. 15-36
    • Narayanaswami, V.1    Ryan, R.O.2
  • 28
    • 0035798681 scopus 로고    scopus 로고
    • Lipid binding-induced conformational change in human apolipoprotein E. Evidence for two lipid-bound states on spherical particles
    • Saito, H., Dhanasekaran, P., Baldwin, F., Weisgraber, K.H., Lund-Katz, S. & Phillips, M.C. (2001) Lipid binding-induced conformational change in human apolipoprotein E. Evidence for two lipid-bound states on spherical particles. J. Biol. Chem. 276, 40949-40954.
    • (2001) J. Biol. Chem. , vol.276 , pp. 40949-40954
    • Saito, H.1    Dhanasekaran, P.2    Baldwin, F.3    Weisgraber, K.H.4    Lund-Katz, S.5    Phillips, M.C.6
  • 30
    • 0030659049 scopus 로고    scopus 로고
    • Trifluoroethanol induces the self-association of specific amphipathic peptides
    • MacPhee, C.E., Perugini, M.A., Sawyer, W.H. & Howlett, G.J. (1997) Trifluoroethanol induces the self-association of specific amphipathic peptides. FEBS Lett. 416, 265-268.
    • (1997) FEBS Lett. , vol.416 , pp. 265-268
    • MacPhee, C.E.1    Perugini, M.A.2    Sawyer, W.H.3    Howlett, G.J.4
  • 31
    • 0026525924 scopus 로고
    • Apolipoprotein E: Phospholipid binding studies with synthetic peptides from the carboxyl terminus
    • Sparrow, J.T., Sparrow, D.A., Fernando, G., Culwell, A.R., Kovar, M. & Gotto, A.M. Jr (1992) Apolipoprotein E: Phospholipid binding studies with synthetic peptides from the carboxyl terminus. Biochemistry 31, 1065-1068.
    • (1992) Biochemistry , vol.31 , pp. 1065-1068
    • Sparrow, J.T.1    Sparrow, D.A.2    Fernando, G.3    Culwell, A.R.4    Kovar, M.5    Gotto A.M., Jr.6
  • 32
    • 0029797723 scopus 로고    scopus 로고
    • Conformations of human apolipoprotein E (263-286) and E (267-289) in aqueous solutions of sodium dodecyl sulfate by CD and 1H NMR
    • Wang, G., Pierens, G.K., Treleaven, W.D., Sparrow, J.T. & Cushley, R.J. (1996) Conformations of human apolipoprotein E (263-286) and E (267-289) in aqueous solutions of sodium dodecyl sulfate by CD and 1H NMR. Biochemistry 35, 10358-10366.
    • (1996) Biochemistry , vol.35 , pp. 10358-10366
    • Wang, G.1    Pierens, G.K.2    Treleaven, W.D.3    Sparrow, J.T.4    Cushley, R.J.5
  • 33
    • 0002498995 scopus 로고
    • Computer-aided interpretation of analytical sedimentation data for proteins
    • Harding, S.E., Rowe, A.J. & Horton, J.C., eds. The Royal Society of Chemistry, Cambridge
    • Laue, T.M., Shah, B.D., Ridgeway, T.M. & Pelletier, S.L. (1992) Computer-aided interpretation of analytical sedimentation data for proteins. In Analytical Ultracentrifugation in Biochemistry and Polymer Science (Harding, S.E., Rowe, A.J. & Horton, J.C., eds), pp. 90-125. The Royal Society of Chemistry, Cambridge.
    • (1992) Analytical Ultracentrifugation in Biochemistry and Polymer Science , pp. 90-125
    • Laue, T.M.1    Shah, B.D.2    Ridgeway, T.M.3    Pelletier, S.L.4
  • 34
    • 0003159229 scopus 로고
    • Die differentialgleichung der ultrazentrifugierung
    • Lamm, O. (1929) Die differentialgleichung der ultrazentrifugierung. Ark. Mat. Astr. Fys. 21B, 1-4.
    • (1929) Ark. Mat. Astr. Fys. , vol.21 B , pp. 1-4
    • Lamm, O.1
  • 35
    • 0031688168 scopus 로고    scopus 로고
    • Sedimentation analysis of noninteracting and self-associating solutes using numerical solutions to the Lamm equation
    • Schuck, P. (1998) Sedimentation analysis of noninteracting and self-associating solutes using numerical solutions to the Lamm equation. Biophys. J. 75, 1503-1512.
    • (1998) Biophys. J. , vol.75 , pp. 1503-1512
    • Schuck, P.1
  • 36
    • 0034009520 scopus 로고    scopus 로고
    • Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and lamm equation modeling
    • Schuck, P. (2000) Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and lamm equation modeling. Biophys. J. 78, 1606-1619.
    • (2000) Biophys. J. , vol.78 , pp. 1606-1619
    • Schuck, P.1
  • 38
    • 0021107170 scopus 로고
    • Triolein-cholesteryl oleatecholesterol-lecithin emulsions: Structural models of triglyceriderich lipoproteins
    • Miller, K.W. & Small, D.M. (1983) Triolein-cholesteryl oleatecholesterol-lecithin emulsions: structural models of triglyceriderich lipoproteins. Biochemistry 22, 443-451.
    • (1983) Biochemistry , vol.22 , pp. 443-451
    • Miller, K.W.1    Small, D.M.2
  • 39
    • 0035971072 scopus 로고    scopus 로고
    • Rotavirus nonstructural protein NSP2 self-assembles into octamers that undergo ligand-induced conformational changes
    • Schuck, P., Taraporewala, Z., McPhie, P. & Patton, J.T. (2001) Rotavirus nonstructural protein NSP2 self-assembles into octamers that undergo ligand-induced conformational changes. J. Biol. Chem. 276, 9679-9687.
    • (2001) J. Biol. Chem. , vol.276 , pp. 9679-9687
    • Schuck, P.1    Taraporewala, Z.2    McPhie, P.3    Patton, J.T.4
  • 40
    • 36149035969 scopus 로고
    • Maximum entropy regularization of Fredholm integral equations of the first kind
    • Amato, U. & Hughes, W. (1991) Maximum entropy regularization of Fredholm integral equations of the first kind. Inverse Problems 7, 793-808.
    • (1991) Inverse Problems , vol.7 , pp. 793-808
    • Amato, U.1    Hughes, W.2
  • 41
    • 0019128929 scopus 로고
    • The mechanism of activation of lecithin: Cholesterol acyltransferase by apolipoprotein A-I and an amphiphilic peptide
    • Yokoyama, S., Fukushima, D., Kupferberg, J.P., Kézdy, F.J. & Kaiser, E.T. (1980) The mechanism of activation of lecithin: cholesterol acyltransferase by apolipoprotein A-I and an amphiphilic peptide. J. Biol. Chem. 255, 7333-7339.
    • (1980) J. Biol. Chem. , vol.255 , pp. 7333-7339
    • Yokoyama, S.1    Fukushima, D.2    Kupferberg, J.P.3    Kézdy, F.J.4    Kaiser, E.T.5
  • 42
    • 0026747656 scopus 로고
    • Boundary analysis in sedimentation transport experiments: A procedure for obtaining sedimentation coefficient distributions using the time derivative of the concentration profile
    • Stafford, W.F. (1992) Boundary analysis in sedimentation transport experiments: A procedure for obtaining sedimentation coefficient distributions using the time derivative of the concentration profile. Anal. Biochem. 203, 295-301.
    • (1992) Anal. Biochem. , vol.203 , pp. 295-301
    • Stafford, W.F.1
  • 43
    • 0034668130 scopus 로고    scopus 로고
    • Determination of the sedimentation coefficient distribution by least-squares boundary modeling
    • Schuck, P. & Rossmanith, P. (2000) Determination of the sedimentation coefficient distribution by least-squares boundary modeling. Biopolymers 54, 328-341.
    • (2000) Biopolymers , vol.54 , pp. 328-341
    • Schuck, P.1    Rossmanith, P.2
  • 44
    • 0017806223 scopus 로고
    • Boundary analysis of sedimentation velocity experiments with monodisperse and paucidisperse solutes
    • van Holde, K.E. & Weischet, W.O. (1978) Boundary analysis of sedimentation velocity experiments with monodisperse and paucidisperse solutes. Biopolymers 17, 1387-1403.
    • (1978) Biopolymers , vol.17 , pp. 1387-1403
    • Van Holde, K.E.1    Weischet, W.O.2
  • 45
    • 0036154258 scopus 로고    scopus 로고
    • Size-distribution analysis of proteins by analytical ultracentrifugation: Strategies and application to model systems
    • Schuck, P., Perugini, M.A., Gonzales, N.R., Howlett, G.J. & Schubert, D. (2002) Size-distribution analysis of proteins by analytical ultracentrifugation: Strategies and application to model systems. Biophys. J. 82, 1096-1111.
    • (2002) Biophys. J. , vol.82 , pp. 1096-1111
    • Schuck, P.1    Perugini, M.A.2    Gonzales, N.R.3    Howlett, G.J.4    Schubert, D.5
  • 46
    • 0001946982 scopus 로고
    • Introduction
    • New, R.R.C., ed. Oxford University Press, New York
    • New, R.R.C. (1990) Introduction. In Liposomes a Practical Approach (New, R.R.C., ed.), pp. 1-32. Oxford University Press, New York.
    • (1990) Liposomes a Practical Approach , pp. 1-32
    • New, R.R.C.1
  • 47
    • 0017356048 scopus 로고
    • Structure and interactions of lipids in human plasma low density lipoproteins
    • Deckelbaum, R.J., Shipley, G. & Small, D.M. (1977) Structure and interactions of lipids in human plasma low density lipoproteins. J. Biol. Chem. 252, 744-754.
    • (1977) J. Biol. Chem. , vol.252 , pp. 744-754
    • Deckelbaum, R.J.1    Shipley, G.2    Small, D.M.3
  • 49
    • 0028341512 scopus 로고
    • Fluorescence study of the motional states of core and surface lipids in native and reconstituted low density lipoproteins
    • Kroon, P.A. (1994) Fluorescence study of the motional states of core and surface lipids in native and reconstituted low density lipoproteins. Biochemistry 33, 4879-4884.
    • (1994) Biochemistry , vol.33 , pp. 4879-4884
    • Kroon, P.A.1
  • 50
    • 0011868850 scopus 로고    scopus 로고
    • Structure and dynamics of human plasma lipoproteins
    • Betteridge, D.J., Illingworth, D.R. & Shepherd, J., eds). Arnold/Oxford University Press, New York
    • Pownall, H.J. & Gotto, A.M. Jr (1999) Structure and dynamics of human plasma lipoproteins. In Lipoproteins in Health and Disease (Betteridge, D.J., Illingworth, D.R. & Shepherd, J., eds), pp. 3-15. Arnold/Oxford University Press, New York.
    • (1999) Lipoproteins in Health and Disease , pp. 3-15
    • Pownall, H.J.1    Gotto A.M., Jr.2
  • 51
    • 0020490909 scopus 로고
    • Microemulsions of phospholipids and cholesterol esters. Protein-free models of low density lipoprotein
    • Ginsburg, G.S., Small, D.M. & Atkinson, D. (1982) Microemulsions of phospholipids and cholesterol esters. Protein-free models of low density lipoprotein. J. Biol. Chem. 257, 8216-8227.
    • (1982) J. Biol. Chem. , vol.257 , pp. 8216-8227
    • Ginsburg, G.S.1    Small, D.M.2    Atkinson, D.3
  • 52
    • 0025124477 scopus 로고
    • Structure and dynamics of microemulsions which mimic the lipid phase of low-density lipoproteins
    • Li, Q.-T., Tilley, L., Sawyer, W.H., Looney, F. & Curtain, C.C. (1990) Structure and dynamics of microemulsions which mimic the lipid phase of low-density lipoproteins. Biochim. Biophys. Acta 1042, 42-50.
    • (1990) Biochim. Biophys. Acta , vol.1042 , pp. 42-50
    • Li, Q.-T.1    Tilley, L.2    Sawyer, W.H.3    Looney, F.4    Curtain, C.C.5
  • 53
    • 0023481281 scopus 로고
    • Dietary fat clearance in normal subjects is regulated by genetic variation in apolipoprotein E
    • Weintraub, M.S., Eisenberg, S. & Breslow, J.L. (1987) Dietary fat clearance in normal subjects is regulated by genetic variation in apolipoprotein E. J. Clin. Invest. 80, 1571-1577.
    • (1987) J. Clin. Invest. , vol.80 , pp. 1571-1577
    • Weintraub, M.S.1    Eisenberg, S.2    Breslow, J.L.3
  • 54
    • 0032824010 scopus 로고    scopus 로고
    • Characterization of apolipoprotein E-containing lipoproteins in cerebrospinal fluid: Effect of phenotype on the distribution of apolipoprotein E
    • Yamauchi, K., Tozuka, M., Hidaka, H., Hidaka, E., Kondo, Y. & Katsuyama, T. (1999) Characterization of apolipoprotein E-containing lipoproteins in cerebrospinal fluid: Effect of phenotype on the distribution of apolipoprotein E. Clin. Chem. 45, 1431-1438.
    • (1999) Clin. Chem. , vol.45 , pp. 1431-1438
    • Yamauchi, K.1    Tozuka, M.2    Hidaka, H.3    Hidaka, E.4    Kondo, Y.5    Katsuyama, T.6
  • 55
    • 0024573697 scopus 로고
    • Association of apolipoprotein E with the low density lipoprotein receptor: Demonstration of its co-operativity on lipid microemulsion particles
    • Funahashi, T., Yokoyama, S. & Yamamoto, A. (1989) Association of apolipoprotein E with the low density lipoprotein receptor: Demonstration of its co-operativity on lipid microemulsion particles. J. Biochem. (Tokyo) 105, 582-587.
    • (1989) J. Biochem. (Tokyo) , vol.105 , pp. 582-587
    • Funahashi, T.1    Yokoyama, S.2    Yamamoto, A.3
  • 56
    • 0025000302 scopus 로고
    • Self-associated tetramer of human apolipoprotein E does not lead to its accumulation on a lipid particle
    • Yokoyama, S. (1990) Self-associated tetramer of human apolipoprotein E does not lead to its accumulation on a lipid particle. Biochim. Biophys. Acta 1047, 99-101.
    • (1990) Biochim. Biophys. Acta , vol.1047 , pp. 99-101
    • Yokoyama, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.