Prior aspirin use in unstable angina patients with modified plasma inflammatory markers and endothelial nitric oxide synthase in neutrophils

European Journal of Clinical Investigation

Volumn 32, Issue 12, 2002, Pages 895-900

  Mateos Cáreres, Petra J ^a   García Méndez, Antonio ^a   Farre J ^a   Sanchez de Miguel L ^a   Gomez J ^a   De Andres, R ^a   Rico, L ^a   Romero, J ^a   López Farré, Antonio ^a   Jimenez P ^a  

^a Hospital UniversitarioFundación Jiménez Díaz   (Spain)

Author keywords

Aspirin; Endothelial nitric oxide synthase; Inflammation; Neutrophils; Unstable angina

Indexed keywords

ACETYLSALICYLIC ACID; CREATINE KINASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA;

AGED; ARTICLE; BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE MARKER; FEMALE; HEART INFARCTION; HOSPITAL ADMISSION; HUMAN; HUMAN TISSUE; INFLAMMATION; MALE; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN EXPRESSION; ST SEGMENT; THORAX PAIN; UNSTABLE ANGINA PECTORIS;

AGED; ANGINA, UNSTABLE; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CORONARY DISEASE; DIABETES COMPLICATIONS; DIABETES MELLITUS; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; HYPERCHOLESTEROLEMIA; INFLAMMATION MEDIATORS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; MALE; NEUTROPHILS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; RISK FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 18744400784     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.2002.01082.x     Document Type: Article

References (32)

1. López-Farré A, Farré J, Sánchez de Miguel L, Romero J, Gomez J, Rico L et al. Trombosis y enfermedad coronaria: Neutrófilos, oxido nítrico y aspirina. Rev Esp Cardiol 1998;51:171-7.
2. Patrono C. Drug therapy: Aspirin as an anti-platelet drug. N Engl J Med 1994;330:1287-94.
3. The RISC Group. Risk of myocardial infarction and death treatment with low dose aspirin and intravenous heparin in patients with unstable coronary artery disease. Lancet 1990;336:827-30.
4. Theroux P, Ouimet H, McCans J, Latour JG, Joly P et al. Aspirin, heparin or both to treat acute unstable angina. N Engl J Med 1988;319:1105-11.
5. Mehta P, Mehta JL. Effects of aspirin in arterial thrombosis: Why don't animals behave the way humans do?. J Am Coll Cardiol 1993;21:511-51.
6. López-Farré A, Caramelo C, Esteban A, Alberola ML, Monton M et al. Effects of aspirin on platelets neutrophils interactions: Role of nitric oxide and endothelin-1. Circulation 1995;91:2080-8.
7. López-Farré A, Riesco A, Digiumi E, Mosquera JR, Caramelo C et al. Aspirin-stimulated nitric oxide production by neutrophils after acute myocardial ischemia in rabbits. Circulation 1996;94:83-7.
8. García-Dorado D, Theroux P, Tornos P, Sambola A, Oliveras J et al. Previous aspirin use may attenuate the severity of the manifestation of acute ischemic syndromes. Ciculation 1995;92:1743-8.
9. Liuzzo G, Biasucci LM, Gallimore JR, Grillo RL, Rebuzzi AG et al. The prognostic value of C-reactive protein and serum amiloid A protein in severe unstable angina. N Engl J Med 1994;331:417-24.
10. Biasicci LM, Vitelli A, Liuzzo G, Altamura S, Caligiuri G et al. Elevated levels of interleukin-6 in unstable angina. Circulation 1996;94:874-7.
11. Ikonomidis I, Andreotti F, Economoun E, Stefanadis C, Toutouzas P, Nihoyannopoulos P. Increased Proinflamatory Cytokines in Patients with Chronic Stable Angina and their Reduction by Aspirin Circulation. 1999;100:793-8.
12. Sanchez de Miguel L, de Frutos T, Gonzalez-Fernandez F, Del Pozo Lahoz C, Jimenez A et al. Aspirin inhibits inducible nitric oxide synthase expression and tumour necrosis factor-α release by cultured smooth muscle cells. Eur J Clin Invest 1999;29:93-9.
13. Alonso J, Sanchez de Miguel L, Montón M, Casado S, López-Farré A. Endothelial cytosolic proteins bind to the 3′-untranslated region of endothelial nitric oxide synthase mRNA. Regulation by tumour necrosis factor-alpha. J Mol Cell Biol 1997;17:5719-26.
14. de Frutos T, Sanchez de Miguel L, Farré J, Gomez J, Romero J et al. Expression of an endothelial-type nitric oxide synthase isoform in human neutrophils: Modification by tumour necrosis factor-alpha and during acute myocardial infarction. J Am Coll Cardiol 2001;37:800-7.
15. Ma XL, Weyrich AS, Lefer DJ, Lefer AM. Disminished basal nitric oxide release after myocardial ischemia and reperfusion promotes neutrophil adherence to coronary endothelium. Circ Res 1993;72:403-12.
16. Smith CJ, Sun D, Hoegler C, Roth BS, Zhao G et al. Reduced gene expression of vascular endothelial NO synthase and cyclooxigenase-1 in heart failure. Circ Res 1996;78:58-64.
17. Kubes P, Suzuki M, Granger DN. Nitric oxide an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA 1991;88:4651-5.
18. Jimenez A, Arriero MM, López-Blaya A, Gonzalez-Fernandez F, Garcia R et al. Regulation of endothelial nitric oxide synthase expression in the vascular wall and in mononuclear cells from hypercholesterolemic rabbits. Circulation 2001;104:1822-30.
19. Ridker PM, Manson JE, Buring JE, Goldhaber SZ, Hennekens CH. Clinical characteristics of non-fatal myocardial infarction among individuals on prophylactic low-dose aspirin therapy. Circulation 1991;22:1338-43.
20. Borzak S, Cannon CP, Kraft PL, Doutha L, Becker RC et al. Effects of prior aspirin and anti-ischemic therapy on outcome of patients with unstable angina. Am J Cardiol 1998;81:678-81.
21. Guillen I, Blanes M, Gomez-Lechon M, Castell JV. Cytokine signaling during myocardial infarction. Sequential appearance IL-2 beta IL-6. Am J Physiol 1995;269:R229-35.
22. Kopp E, Ghosh S. Inhibition of NF-KB by sodium salicylate and aspirin. Science 1994;265:956-9.
23. Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH. Inflammation, aspirin and the risk of cardiovascular disease in apparently healthy men. New Engl J Med 1997;336:973-9.
24. Kennon S, Price CP, Mills PG, Ranjadayalan K, Cooper J, Clarke H. The effect of aspirin on C-reactive protein as a marker of risk in unstable angina. J Am Coll Cardiol 2001;37:1266-70.
25. You M, Flick LMYuD, Feng GS. Modulation of the nuclear factor kappa B pathway by Shp-2 tyrosime phosphatase in mediating the induction of interleukin (IL)-6 by IL-1 or tumour necrosis factor. J Exp Med 2001;93:101-10.
26. Fan H, Sun B, Gu Q, Lafond-Walker A, Cao S, Becker LC. Oxygen radicals trigger activation of NF-kappa B and AP-1 and upregulation of ICAM-1 in reperfused canine heart. Am J Physiol (Heart Circ Physiol), 2002:282:HI778-HI786.
27. 2. Blood Coagul Fibrinolysis 1992;3:309-13.
28. Dendorfer U, Oettgen P, Libermann TA. Interleukin-6 gene expression by prostaglandin and cyclic AMP mediated by multiple regulatory elements. Am J Ther 1995;2:660-5.
29. Arriero MM, de la Pinta JC, Escribano M, Celdran A, Muñoz L et al. Aspirin prevents Escherichia coli Lipopolysaccharide- and Staphylococcus aureus-induced down regulation of endothelial nitric oxide synthase expression in guinea pig pericardial tissue. Circ Res 2002;90:719-27.
30. Ridker PM, Hennekens CH, Roitman-Johnson B, Stampfer MJ, Allen J. Plasma concentration of soluble intercellular adhesion molecule 1 and risks of future myocardial infarction in apparently healthy men. Lancet 1998;351:88-92.
31. Ridker PM, Rifai N, Stampfer MJ, Hennekens CH. Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation 2000;101:1767-72.
32. Schachinger V, Britten MB, Zeiher AM. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 2000;101:1899-906.