Effects of prior aspirin and anti-ischemic therapy on outcome of patients with unstable angina

American Journal of Cardiology

Volumn 81, Issue 6, 1998, Pages 678-681

  Borzak, Steven ^a   Cannon, Christopher P ^b   Kraft, Phillip L ^b   Douthat, Lori ^b   Becker, Richard C ^b   Palmeri, Sebastian T ^b   Henry, Timothy ^b   Hochman, Judith S ^b   Fuchs, Joanna ^b   Antman, Elliott M ^b   McCabe, Carolyn ^b   Braunwald, Eugene ^b  

^a HENRY FORD HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM ANTAGONIST; HIRULOG; NITRIC ACID DERIVATIVE;

ACUTE HEART INFARCTION; ADULT; AGED; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HEART MUSCLE ISCHEMIA; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; TREATMENT OUTCOME; UNSTABLE ANGINA PECTORIS;

ADRENERGIC BETA-ANTAGONISTS; ADULT; AGED; ANGINA, UNSTABLE; ASPIRIN; CALCIUM CHANNEL BLOCKERS; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; MALE; MIDDLE AGED; NITROGLYCERIN; ODDS RATIO; PLATELET AGGREGATION INHIBITORS; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; VASODILATOR AGENTS;

EID: 0032521203     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9149(97)01006-0     Document Type: Article

References (30)

1. Cairas JA, Gent M, Singer J, Finnie KJ, Froggart GM, Holder DA, Jablonsky G, Kostuk WJ, Melendez LJ, Myers MG. Aspirin, sulfinpyrazone or both in unstable angina: results of a Canadian multicenter trial. N Engl J Med 1985;313: 1369-1375.
2. Lewis HD, Jr, Davis JW, Archibald DG, Steinke WE, Smitherman TC, Doherty JE III, Schnaper HW, Le Winter MM, Linares E, Pouget JM, Sabharwal SC, Chester E, DeMots H. Protective effects of aspirin against acute myocardial infarction and death in men with unstable angina: results of a Veterans Administration Cooperative Study. N Engl J Med 1983;309:396-403.
3. The RISC Group. Risk of myocardial infarction and death during treatment with low dose aspirin and intravenous heparin in men with unstable coronary artery disease. Lancet 1990;336:827-830.
4. Theroux P, Ouimet H, McCans J, Latour JG, Joly P, Levy G, Pelletier E, Juneau M, Stasiak J, DeGuise P. Aspirin, heparin or both to treat acute unstable angina. N Engl J Med 1988;319:1105-1111.
5. Grambow DW, Topol EJ. Effect of maximal medical therapy on refractoriness of unstable angina pectoris. Am J Cardiol 1992;70:577-581.
6. Braunwald E, Mark DB, Jones RH, Cheitlin MD, Fuster V, McCauley KM, Edwards C, Green LA, Mushlin AI, Swain JA, Smith EE, Cowan M, Rose GC, Concannon CA, Grines CL, Brown L, Lytel BW, Goldman L, Topol EJ, Willerson JT, Brown J, Archibald N. Unstable angina: diagnosis and management. May 1994. Clinical practice guideline number 10 (amended) AHCPR (publication no. 94-0602). Rockville, Md.: Agency for Health Care Policy and Research and the National Heart, Lung, and Blood Institute, Public Health Service, US Department of Health and Human Services.
7. Telford AM, Wilson C. Trial of heparin versus atenolol in prevention of myocardial infarction in intermediate coronary syndrome. Lancet 1981;1:1225-1228.
8. Curfman GD, Heinsimer JA, Lozner EC, Fung HL. Intravenous nitroglycerin in the treatment of spontaneous angina pectoris: a prospective, randomized trial. Circulation 1983;67:276-282.
9. HINT Research Group. Early treatment of unstable angina in the coronary care unit: a randomised, double-blind, placebo controlled comparison of recurrent ischemia in patients treated with nifedipine or metoprolol or both. Br Heart J 1986;56:400-413.
10. Theroux P, Taeymans Y, Morissette D, Bosch X, Pelletier GB, Waters DD. A randomized study comparing propranolol and diltiazem in the treatment of unstable angina. J Am Coll Cardiol 1985;5:717-722.
11. Norris RM, Sammel NL, Clarke ED, Smith WM. Protective effect of propranolol in threatened acute myocardial infarction. Lancet 1978;2:907-909.
12. Kaplan K, Davison R, Parker M, Przybklenk J, Teagarden JR, Lesch M. Intravenous nitroglycerin for the treatment of angina at rest unresponsive to standard nitrate therapy. Am J Cardiol 1983;51:694-698.
13. Theroux P. Anti-platelet and anti-thrombotic therapy in unstable angina. Am J Cardiol 1991;68:92B-98B.
14. Cohen M, Adams P, Parry G, Xiong J, Chamberlain D, Wieczorek I, Fox KA, Krommel R, Fuster V. Combination anti-thrombotic therapy in unstable rest angina and non-Q-wave infarction in nonprior aspirin users: primary end points analysis from the ATACS trial. Circulation 1994;89:81-88.
15. Fuchs J, Cannon CP, and the TIMI-7 Investigators. Hirulog in the treatment of unstable angina: results of the Thrombin Inhibition in Myocardial Ischemia (TIMI) 7 Trial. Circulation 1995;92:727-733.
16. Cannon CP, Thompson B, McCabe CH, Mueller HS, Kirshenbaum JM, Herson S, Nasmith JB, Chaitman BR, Braunwald E. Predictors of non-Q-wave acute myocardial infarction in patients with acute ischemic syndromes: an analysis from the Thrombolysis In Myocardial Ischemia (TIMI) III trials. Am J Cardiol 1995;75:977-981.
17. Garcia-Dorado D, Theroux P, Tornos P, Sambola A, Oliveras J, Santos M, Soler JS. Previous aspirin may attenuate the severity of the manifestations of acute ischemic syndromes. Circulation 1995;92:1743-1748.
18. Col NF, Yarzebski J, Gore JM, Alpert JS, Goldberg RJ. Does aspirin consumption affect the presentation or severity of acute myocardial infarction? Arch Intern Med 1995;155:1386-1389.
19. Ridker P, Manson J, Buring J, Goldhaber SZ, Hennekens CH. Clinical characteristics of nonfatal myocardial infarction among individuals on prophylactic low-dose aspirin therapy. Circulation 1991;84:708-711.
20. Schreiber TL, Mancina G, Bunnell P, Tenney RD, McNulty A, Kikel M, Miller DH, Zola BE, Tracy R, Stump D. Unstable angina or non-Q-wave infarction despite long-term aspirin: response to thrombolytic therapy with implications on mechanisms. Am Heart J 1990;120:248-255.
21. Hagani K, Shah P, Cercek B. Unstable angina developing in patients on chronic aspirin therapy is associated with an increased risk of early adverse cardiac events (abst). J Am Coll Cardiol 1993;21:270A.
22. Cohen M, Adams P, McBride R, Blanke H, Fuster V, and the Anti-thrombotic Therapy in Acute Coronary Syndromes Research Group. Prospective comparison of patient characteristics and outcome of non-prior aspirin users versus aspirin users with unstable angina or non-Q-wave myocardial infarction treated with combination anti-thrombotic therapy. J Thromb Thrombol 1997;4:275-280.
23. The TIMI IIIA Investigators. Early effects of tissue-type plasminogen activator added to conventional therapy on the culprit lesion in patients presenting with ischemic cardiac pain at rest: results of the Thrombolysis In Myocardial Ischemia (TIMI IIIA) trial. Circulation 1993;87:38-52.
24. Kloner RA, Shook T, Przyklenk K, Davis VG, Junio L, Matthews RV, Burstein S, Gibson M, Poole WK, Cannon CP. Previous angina alters in-hospital outcome in TIMI 4: a clinical correlate to preconditioning? Circulation 1995;91: 37-45.
25. Knight CJ, Panesar M, Wilson DJ, Chronos NA, Patal D, Fox K, Goodall AH. Different effects of calcium antagonists, nitrates, and beta blockers on platelet function: possible importance for the treatment of unstable angina. Circulation 1997;95:125-132.
26. Cannon CP, McCabe CH, Borzak S, Henry TD, Tischler MD, Mueller HS, Feldman R, Palmeri ST, Ault K, Hamilton SA, Rothman JM, Novotny WF, Braunwald E, and the TIMI 12 Investigators. A randomized trial of oral platelet glycoprotein IIb/IIIa inhibitor, sibrafiban, in patients after an acute coronary syndrome: results of the TIMI 12 trial. Circulation 1998; in press.
27. Lindahl B, Venge P, Wallentin L, for the FRISC Study Group. Relation between troponin T and the risk of subsequent cardiac events in unstable coronary artery disease. Circulation 1996;93:1651-1657.
28. Cannon CP, McCabe CH, Stone PH, Rogers WJ, Schactman M, Thompson BN, Pearce DJ, Diver DJ, Kells C, Feldman T, Williams M, Gibson RS, Kronenberg MW, Ganz LI, Andersen HV, Braunwald E. The electrocardiogram predicts one-year outcome of patients with unstable angina and non-Q-wave myocardial infarction: results of the TIMI III Registry ECG Ancillary Study. J Am Coll Cardiol 1997;30:133-140.
29. Betriu A, Heras M, Cohen M, Fuster V. Unstable angina: outcome according to clinical presentation. J Am Coll Cardiol 1992;19:1659-1663.
30. Ouyang P, Brinker J, Mellitus D, Weisfeldt ML, Gerstenblith G. Variables predictive of successful medical therapy in patients with unstable angina: selection by multivariate analysis from clinical, electrocardiographic, and angiographic evaluations. Circulation 1984;70:367-376.