A metabolic enzyme doing double duty as a transcription factor

BioEssays

Volumn 27, Issue 5, 2005, Pages 467-471

  Bhardwaj, Anjana ^a   Wilkinson, Miles F ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; MESSENGER RNA PRECURSOR; ORNITHINE; PROTEIN ARG5 6; REGULATOR PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ALDEHYDE DEHYDROGENASE; ARG5,6 PROTEIN, S CEREVISIAE; MESSENGER RNA; MULTIENZYME COMPLEX; PHOSPHOTRANSFERASE;

AMINO ACID SYNTHESIS; GENE CONTROL; HUMAN; METABOLIC REGULATION; NONHUMAN; PROMOTER REGION; PROTEIN BINDING; REVIEW; RNA METABOLISM; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR EVOLUTION;

ALDEHYDE OXIDOREDUCTASES; ANIMALS; ENZYMES; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION; HUMANS; MULTIENZYME COMPLEXES; PHOSPHOTRANSFERASES (CARBOXYL GROUP ACCEPTOR); RNA, MESSENGER; TRANSCRIPTION FACTORS;

EID: 18744396678     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.20232     Document Type: Review

References (42)

1. Hall DA, Zhu H, Zhu X, Royce T, Gerstein M, et al. 2004. Regulation of gene expression by a metabolic enzyme. Science 306:482-484.
2. Wilkinson MF, Shyu AB. 2001. Multifunctional regulatory proteins that control gene expression in both the nucleus and the cytoplasm. Bioessays 23:775-787.
3. Cassiday LA, Maher LJ 3rd. 2002. Having it both ways: transcription factors that bind DNA and RNA. Nucleic Acids Res 30:4118-4126.
4. Ladomery M, Dellaire G. 2002. Multifunctional zinc finger proteins in development and disease. Ann Hum Genet 66:331-342.
5. Fontoura BM, Atienza CA, Sorokina EA, Morimoto T, Carroll RB. 1997. Cytoplasmic p53 polypeptide is associated with ribosomes. Mol Cell Biol 17:3146-3154.
6. Ewen ME, Oliver CJ, Sluss HK, Miller SJ, Peeper DS. 1995. p53-dependent repression of CDK4 translation in TGF-beta-induced G1 cell-cycle arrest. Genes Dev 9:204-217.
7. Miller SJ, Suthiphongchai T, Zambetti GP, Ewen ME. 2000. p53 binds selectively to the 5′ untranslated region of cdk4, an RNA element necessary and sufficient for transforming growth factor beta- and p53-mediated translational inhibition of cdk4. Mol Cell Biol 20:8420-8431.
8. Pieler T, Theunissen O. 1993. TFIIIA: nine fingers-three hands? Trends Biochem Sci 18:226-230.
9. Searles MA, Lu D, Klug A. 2000. The role of the central zinc fingers of transcription factor IIIA in binding to 5 S RNA. J Mol Biol 301:47-60.
10. Theunissen O, Rudt F, Guddat U, Mentzel H, Pieler T. 1992. RNA and DNA binding zinc fingers in Xenopus TFIIIA. Cell 71:679-690.
11. Piatigorsky J. 2003. Crystallin genes: specialization by changes in gene regulation may precede gene duplication. J Struct Funct Genomics 3:131-137.
12. Nagy E, Rigby WF. 1995. Glyceraldehyde-3-phosphate dehydrogenase selectively binds AU-rich RNA in the NAD(+)-binding region (Rossmann fold). J Biol Chem 270:2755-2763.
13. Ryazanov AG. 1985. Glyceraldehyde-3-phosphate dehydrogenase is one of the three major RNA-binding proteins of rabbit reticulocytes. FEBS Lett 192:131-134.
14. Singh R, Green MR. 1993. Sequence-specific binding of transfer RNA by glyceraldehyde-3-phosphate dehydrogenase. Science 259:365-368.
15. McGowan K, Pekala PH. 1996. Dehydrogenase binding to the 3′-untranslated region of GLUT1 mRNA. Biochem Biophys Res Commun 221:42-45.
16. Sioud M, Jespersen L. 1996. Enhancement of hammerhead ribozyme catalysis by glyceraldehyde-3-phosphate dehydrogenase. J Mol Biol 257:775-789.
17. De BP, Gupta S, Zhao H, Drazba JA, Banerjee AK. 1996. Specific interaction in vitro and in vivo of glyceraldehyde-3-phosphate dehydrogenase and LA protein with cis-acting RNAs of human parainfluenza virus type 3. J Biol Chem 271:24728-24735.
18. Petrik J, Parker H, Alexander GJ. 1999. Human hepatic glyceraldehyde-3-phosphate dehydrogenase binds to the poly(U) tract of the 3′ non-coding region of hepatitis C virus genomic RNA. J Gen Virol 80(Pt 12): 3109-3113.
19. Nakagawa J, Waldner H, Meyer-Monard S, Hofsteenge J, Jeno P, et al. 1995. AUH, a gene encoding an AU-specific RNA binding protein with intrinsic enoyl-CoA hydratase activity. Proc Natl Acad Sci USA 92:2051-2055.
20. Bateman JM, Perlman PS, Butow RA. 2002. Mutational bisection of the mitochondrial DNA stability and amino acid biosynthetic functions of ilv5p of budding yeast. Genetics 161:1043-1052.
21. Zheng L, Roeder RG, Luo Y. 2003. S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component. Cell 114:255-266.
22. Meyer-Siegler K, Mauro DJ, Seal G, Wurzer J, deRiel JK, et al. 1991. A human nuclear uracil DNA glycosylase is the 37-kDa subunit of glyceraldehyde-3-phosphate dehydrogenase. Proc Natl Acad Sci USA 88:8460-8464.
23. Landweber LF, Gilbert W. 1993. RNA editing as a source of genetic variation. Nature 363:179-182.
24. Vilardell J, Yu SJ, Warner JR. 2000. Multiple functions of an evolutionary conserved RNA binding domain. Mol Cell 5:761-766.
25. Serganov A, Polonskaia A, Ehresmann B, Ehresmann C, Patel DJ. 2003. Ribosomal protein S15 represses its own translation via adaptation of an rRNA-like fold within its mRNA. Embo J 22:1898-1908.
26. Tai N, Schmitz JC, Liu J, Lin X, Bailly M, et al. 2004. Translational autoregulation of thymidylate synthase and dihydrofolate reductase. Front Biosci 9:2521-2526.
27. Springer M, Graffe M, Dondon J, Grunberg-Manago M. 1989. tRNA-like structures and gene regulation at the translational level: a case of molecular mimicry in Escherichia coli. Embo J 8:2417-2424.
28. Wollerton MC, Gooding C, Wagner EJ, Garcia-Blanco MA, Smith CW. 2004. Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay. Mol Cell 13:91-100.
29. Gunderson SI, Polycarpou-Schwarz M, Mattaj IW. 1998. U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase. Mol Cell 1:255-264.
30. Minsky N, Oren M. 2004. The RING domain of Mdm2 mediates histone ubiquitylation and transcriptional repression. Mol Cell 16:631-639.
31. Gallagher JE, Dunbar DA, Granneman S, Mitchell BM, Osheim Y, et al. 2004. RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components. Genes Dev 18:2506-2517.
32. Gallia GL, Johnson EM, Khalili K. 2000. Puralpha: a multifunctional single-stranded DNA- and RNA-binding protein. Nucleic Acids Res 28:3197-3205.
33. Hecht NB. 2000. Intracellular and intercellular transport of many germ cell mRNAs is mediated by the DNA- and RNA-binding protein, testis-brain-RNA- binding protein (TB-RBP). Mol Reprod Dev 56:252-253.
34. Wool IG. 1996. Extraribosomal functions of ribosomal proteins. Trends Biochem Sci 21:164-165.
35. Nagy E, Henics T, Eckert M, Miseta A, Lightowlers RN, et al. 2000. Identification of the NAD(+)-binding fold of glyceraldehyde-3-phosphate dehydrogenase as a novel RNA-binding domain. Biochem Biophys Res Commun 275:253-260.
36. Chu E, Koeller DM, Casey JL, Drake JC, Chabner BA, et al. 1991. Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase. Proc Natl Acad Sci USA 88:8977-8981.
37. Fester T, Schuster H. 1995. Potato mitochondrial manganese superoxide dismutase is an RNA-binding protein. Biochem Mol Biol Int 36: 67-75.
38. Jimenez GS, Khan SH, Stommel JM, Wahl GM. 1999. Wahl1 p53 regulation by post-translational modification and nuclear retention in response to diverse stresses. Oncogene 18:7656-7665.
39. Thut CJ, Goodrich JA, Tjian R. 1997. Repression of p53-mediated transcription by MDM2: a dual mechanism. Genes Dev 11:1974-1986.
40. Daujat S, Neel H, Piette J. 2001. MDM2: life without p53. Trends Genet 17:459-464.
41. Usui-Aoki K, Ito H, Ui-Tei K, Takahashi K, Lukacsovich T, et al. 2000. Formation of the male-specific muscle in female Drosophila by ectopic fruitless expression. Nature Cell Biol 2:500-506.
42. Shyu AB, Wilkinson MF. 2000. The double lives of shuttling mRNA binding proteins. Cell 102:135-138.