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Volumn 85, Issue 5, 2005, Pages 624-632

Progesterone enhances cytokine-stimulated nitric oxide synthase II expression and cell death in human breast cancer cells

Author keywords

Apoptosis; Breast cancer; Nitric oxide; NOSII; Progesterone; Transcription

Indexed keywords

CYTOKINE; ESTRADIOL; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; NITRIC OXIDE; PROGESTERONE; PROGESTERONE RECEPTOR; STEROID HORMONE; TUMOR NECROSIS FACTOR ALPHA;

EID: 18744385845     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3700267     Document Type: Article
Times cited : (13)

References (44)
  • 1
    • 0028332056 scopus 로고
    • Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions
    • Forstermann U, Gloss EI, Pollock JS, et al. Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions. Hypertension 1994;23:1121-1131.
    • (1994) Hypertension , vol.23 , pp. 1121-1131
    • Forstermann, U.1    Gloss, E.I.2    Pollock, J.S.3
  • 2
    • 0039558662 scopus 로고    scopus 로고
    • Expressional control of the 'constitutive' isoforms of nitric oxide synthase (NOS I and NOS III)
    • Forstermann U, Boissel JP, Kleinert H. Expressional control of the 'constitutive' isoforms of nitric oxide synthase (NOS I and NOS III). FASEB J 1998;12:773-790.
    • (1998) FASEB J , vol.12 , pp. 773-790
    • Forstermann, U.1    Boissel, J.P.2    Kleinert, H.3
  • 3
    • 0042737444 scopus 로고    scopus 로고
    • The role of nitric oxide in cancer
    • Xu W, Liu LZ, Loizidou M, et al. The role of nitric oxide in cancer. Cell Res 2002;12:311-320.
    • (2002) Cell Res , vol.12 , pp. 311-320
    • Xu, W.1    Liu, L.Z.2    Loizidou, M.3
  • 4
    • 0034054449 scopus 로고    scopus 로고
    • Molecular mechanisms regulating iNOS expression in various cell types
    • Rao KM. Molecular mechanisms regulating iNOS expression in various cell types. J Toxicol Environ Health B Grit Rev 2000;3:27-58.
    • (2000) J Toxicol Environ Health B Grit Rev , vol.3 , pp. 27-58
    • Rao, K.M.1
  • 5
    • 0032510832 scopus 로고    scopus 로고
    • Multiple NF-kappaB enhancer elements regulate cytokine induction of the human inducible nitric oxide synthase gene
    • Taylor BS, de Vera ME, Ganster RW, et al. Multiple NF-kappaB enhancer elements regulate cytokine induction of the human inducible nitric oxide synthase gene. J Biol Chem 1998;273:15148-15156.
    • (1998) J Biol Chem , vol.273 , pp. 15148-15156
    • Taylor, B.S.1    De Vera, M.E.2    Ganster, R.W.3
  • 6
    • 0035896597 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases mediate activator protein-1-dependent human inducible nitric-oxide synthase promoter activation
    • Kristof AS, Marks-Konczalik J, Moss J. Mitogen-activated protein kinases mediate activator protein-1-dependent human inducible nitric-oxide synthase promoter activation. J Biol Chem 2001;276:8445-8452.
    • (2001) J Biol Chem , vol.276 , pp. 8445-8452
    • Kristof, A.S.1    Marks-Konczalik, J.2    Moss, J.3
  • 7
    • 0031679445 scopus 로고    scopus 로고
    • Cytokine induction of NO synthase II in human DLD-1 cells: Roles of the JAK-STAT, AP-1 and NF-kappaB-signaling pathways
    • Kleinert H, Wallerath T, Fritz G, et al. Cytokine induction of NO synthase II in human DLD-1 cells: roles of the JAK-STAT, AP-1 and NF-kappaB-signaling pathways. Br J Pharmacol 1998;125:193-201.
    • (1998) Br J Pharmacol , vol.125 , pp. 193-201
    • Kleinert, H.1    Wallerath, T.2    Fritz, G.3
  • 8
    • 0028078839 scopus 로고
    • Mapping of the gene for inducible nitric oxide (NO) synthase of mouse macrophages to chromosome 11, close to Evi-2, nu, and Idd-4
    • Jenkins NA, Rothe H, Gilbert DJ, et al. Mapping of the gene for inducible nitric oxide (NO) synthase of mouse macrophages to chromosome 11, close to Evi-2, nu, and Idd-4. Genomics 1994;19:402-404.
    • (1994) Genomics , vol.19 , pp. 402-404
    • Jenkins, N.A.1    Rothe, H.2    Gilbert, D.J.3
  • 10
    • 0028929559 scopus 로고
    • Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells
    • Xie K, Huang S, Dong Z, et al. Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells. J Exp Med 1995;181:1333-1343.
    • (1995) J Exp Med , vol.181 , pp. 1333-1343
    • Xie, K.1    Huang, S.2    Dong, Z.3
  • 11
    • 0032879957 scopus 로고    scopus 로고
    • Nitric oxide synthase in human breast cancer is associated with tumor grade, proliferation rate, and expression of progesterone receptors
    • Reveneau S, Arnould L, Jolimoy G, et al. Nitric oxide synthase in human breast cancer is associated with tumor grade, proliferation rate, and expression of progesterone receptors. Lab Invest 1999;79:1215-1225.
    • (1999) Lab Invest , vol.79 , pp. 1215-1225
    • Reveneau, S.1    Arnould, L.2    Jolimoy, G.3
  • 12
    • 0031984809 scopus 로고    scopus 로고
    • Frequent nitric oxide synthase-2 expression in human colon adenomas: Implication for tumor angiogenesis and colon cancer progression
    • Ambs S, Merriam WG, Bennett WP, et al. Frequent nitric oxide synthase-2 expression in human colon adenomas: implication for tumor angiogenesis and colon cancer progression. Cancer Res 1998;58:334-341.
    • (1998) Cancer Res , vol.58 , pp. 334-341
    • Ambs, S.1    Merriam, W.G.2    Bennett, W.P.3
  • 13
    • 0032698082 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase in human breast cancer depends on tumor grade
    • Tschugguel W, Schneeberger C, Unfried G, et al. Expression of inducible nitric oxide synthase in human breast cancer depends on tumor grade. Breast Cancer Res Treat 1999;56:145-151.
    • (1999) Breast Cancer Res Treat , vol.56 , pp. 145-151
    • Tschugguel, W.1    Schneeberger, C.2    Unfried, G.3
  • 14
    • 0034083406 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase expression, apoptosis, and angiogenesis in in situ and invasive breast carcinomas
    • Vakkala M, Kahlos K, Lakari E, et al. Inducible nitric oxide synthase expression, apoptosis, and angiogenesis in in situ and invasive breast carcinomas. Clin Cancer Res 2000;6:2408-2416.
    • (2000) Clin Cancer Res , vol.6 , pp. 2408-2416
    • Vakkala, M.1    Kahlos, K.2    Lakari, E.3
  • 15
    • 0017700706 scopus 로고
    • Estrogen receptor as an independent prognostic factor for early recurrence in breast cancer
    • Knight WA, Livingston RB, Gregory EJ, et al. Estrogen receptor as an independent prognostic factor for early recurrence in breast cancer. Cancer Res 1977;37:4669-4671.
    • (1977) Cancer Res , vol.37 , pp. 4669-4671
    • Knight, W.A.1    Livingston, R.B.2    Gregory, E.J.3
  • 16
    • 0020570582 scopus 로고
    • Progesterone and estrogen receptors as prognostic variables in breast cancer
    • Mason BH, Holdaway IM, Mullins PR, et al. Progesterone and estrogen receptors as prognostic variables in breast cancer. Cancer Res 1983;43:2985-2990.
    • (1983) Cancer Res , vol.43 , pp. 2985-2990
    • Mason, B.H.1    Holdaway, I.M.2    Mullins, P.R.3
  • 17
    • 0019947954 scopus 로고
    • Steroid hormone receptors and carcinoma of the breast
    • McGuire WL, Osborne CK, Clark GM, et al. Steroid hormone receptors and carcinoma of the breast. Am J Physiol 1982;243:E99-E102.
    • (1982) Am J Physiol , vol.243
    • McGuire, W.L.1    Osborne, C.K.2    Clark, G.M.3
  • 18
    • 0021349054 scopus 로고
    • Steroid-hormone receptors and survival after first relapse in breast cancer
    • Howell A, Barnes DM, Harland RN, et al. Steroid-hormone receptors and survival after first relapse in breast cancer. Lancet 1984;1:588-591.
    • (1984) Lancet , vol.1 , pp. 588-591
    • Howell, A.1    Barnes, D.M.2    Harland, R.N.3
  • 19
    • 0021925411 scopus 로고
    • Significance of estrogen and progesterone receptors, disease-free interval, and site of first metastasis on survival of breast cancer patients
    • Alanko A, Heinonen E, Scheinin T, et al. Significance of estrogen and progesterone receptors, disease-free interval, and site of first metastasis on survival of breast cancer patients. Cancer 1985;56:1696-1700.
    • (1985) Cancer , vol.56 , pp. 1696-1700
    • Alanko, A.1    Heinonen, E.2    Scheinin, T.3
  • 20
    • 0034293211 scopus 로고    scopus 로고
    • eNOS expression is associated with the estrogen and progesterone receptor status in invasive breast carcinoma
    • Vakkala M, Paakko P, Soini Y. eNOS expression is associated with the estrogen and progesterone receptor status in invasive breast carcinoma. Int J Oncol 2000;17:667-671.
    • (2000) Int J Oncol , vol.17 , pp. 667-671
    • Vakkala, M.1    Paakko, P.2    Soini, Y.3
  • 21
    • 0031884157 scopus 로고    scopus 로고
    • Estrogens increase transcription of the human endothelial NO synthase gene: Analysis of the transcription factors involved
    • Kleinert H, Wallerath T, Euchenhofer C, et al. Estrogens increase transcription of the human endothelial NO synthase gene: analysis of the transcription factors involved. Hypertension 1998;31:582-588.
    • (1998) Hypertension , vol.31 , pp. 582-588
    • Kleinert, H.1    Wallerath, T.2    Euchenhofer, C.3
  • 22
    • 0033623797 scopus 로고    scopus 로고
    • Estradiol-17beta inhibits nitric oxide synthase (NOS)-II and stimulates NOS-III gene expression in the rat uterus
    • Yallampalli C, Dong YL. Estradiol-17beta inhibits nitric oxide synthase (NOS)-II and stimulates NOS-III gene expression in the rat uterus. Biol Reprod 2000;63:34-41.
    • (2000) Biol Reprod , vol.63 , pp. 34-41
    • Yallampalli, C.1    Dong, Y.L.2
  • 23
    • 0030061515 scopus 로고    scopus 로고
    • Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: Initial analysis of the human NOS2 promoter
    • de Vera ME, Shapiro RA, Nussler AK, et al. Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: initial analysis of the human NOS2 promoter. Proc Natl Acad Sci USA 1996;93:1054-1059.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1054-1059
    • De Vera, M.E.1    Shapiro, R.A.2    Nussler, A.K.3
  • 24
    • 0036546549 scopus 로고    scopus 로고
    • A represser in the proximal human inducible nitric oxide synthase promoter modulates transcriptional activation
    • Pance A, Chantome A, Reveneau S, et al. A represser in the proximal human inducible nitric oxide synthase promoter modulates transcriptional activation. FASEB J 2002;16:631-633.
    • (2002) FASEB J , vol.16 , pp. 631-633
    • Pance, A.1    Chantome, A.2    Reveneau, S.3
  • 25
    • 0034575798 scopus 로고    scopus 로고
    • Heat shock enhances transcriptional activation of the murine-inducible nitric oxide synthase gene
    • Goldring CE, Reveneau S, Chantome A, et al. Heat shock enhances transcriptional activation of the murine-inducible nitric oxide synthase gene. FASEB J 2000;14:2393-2395.
    • (2000) FASEB J , vol.14 , pp. 2393-2395
    • Goldring, C.E.1    Reveneau, S.2    Chantome, A.3
  • 26
    • 0020448709 scopus 로고
    • Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids
    • Green LC, Wagner DA, Glogowski J, et al. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal Biochem 1982;126:131-138.
    • (1982) Anal Biochem , vol.126 , pp. 131-138
    • Green, L.C.1    Wagner, D.A.2    Glogowski, J.3
  • 27
    • 0034981494 scopus 로고    scopus 로고
    • Hormonal regulation of tumor suppressor proteins in breast cancer cells
    • Moudgil VK, Dinda S, Khattree N, et al. Hormonal regulation of tumor suppressor proteins in breast cancer cells. J Steroid Biochem Mol Biol 2001;76:105-117.
    • (2001) J Steroid Biochem Mol Biol , vol.76 , pp. 105-117
    • Moudgil, V.K.1    Dinda, S.2    Khattree, N.3
  • 28
    • 0031896927 scopus 로고    scopus 로고
    • Involvement of protein kinases in the induction of NO synthase II in human DLD-1 cells
    • Kleinert H, Euchenhofer C, Fritz G, et al. Involvement of protein kinases in the induction of NO synthase II in human DLD-1 cells. Br J Pharmacol 1998;123:1716-1722.
    • (1998) Br J Pharmacol , vol.123 , pp. 1716-1722
    • Kleinert, H.1    Euchenhofer, C.2    Fritz, G.3
  • 29
    • 0028890402 scopus 로고
    • Cellular localization and hormonal regulation of inducible nitric oxide synthase in cycling mouse uterus
    • Huang J, Roby KF, Pace JL, et al. Cellular localization and hormonal regulation of inducible nitric oxide synthase in cycling mouse uterus. J Leukoc Biol 1995;57:27-35.
    • (1995) J Leukoc Biol , vol.57 , pp. 27-35
    • Huang, J.1    Roby, K.F.2    Pace, J.L.3
  • 30
    • 0034932816 scopus 로고    scopus 로고
    • Inhibitory effects of 17beta-estradiol and progesterone on ovarian carcinoma cell proliferation: A potential role for inducible nitric oxide synthase
    • Keith Bechtel M, Bonavida B. Inhibitory effects of 17beta-estradiol and progesterone on ovarian carcinoma cell proliferation: a potential role for inducible nitric oxide synthase. Gynecol Oncol 2001;82:127-138.
    • (2001) Gynecol Oncol , vol.82 , pp. 127-138
    • Keith Bechtel, M.1    Bonavida, B.2
  • 31
    • 0033854965 scopus 로고    scopus 로고
    • Onapristone (ZK299) blocks the suppressive effect of progesterone, but not that of dexamethasone, on inducible nitric oxide synthase gene expression and nitric oxide production in murine macrophages
    • Kohmura Y, Kirikae T, Kirikae F, et al. Onapristone (ZK299) blocks the suppressive effect of progesterone, but not that of dexamethasone, on inducible nitric oxide synthase gene expression and nitric oxide production in murine macrophages. Int J Immunopharmacol 2000;22:765-774.
    • (2000) Int J Immunopharmacol , vol.22 , pp. 765-774
    • Kohmura, Y.1    Kirikae, T.2    Kirikae, F.3
  • 32
    • 0034244240 scopus 로고    scopus 로고
    • Progesterone inhibits inducible nitric oxide synthase mRNA expression in human intestinal epithelial cells
    • Salzman AL, Linn SC, Szabo C. Progesterone inhibits inducible nitric oxide synthase mRNA expression in human intestinal epithelial cells. Int J Mol Med 2000;6:209-216.
    • (2000) Int J Mol Med , vol.6 , pp. 209-216
    • Salzman, A.L.1    Linn, S.C.2    Szabo, C.3
  • 33
    • 0036870091 scopus 로고    scopus 로고
    • Modulation of cdk2, cyclin D1, p16INK4a, p21WAF and p27Kip1 expression in endothelial cells by TNF/IFN gamma
    • Dormond O, Lejeune FJ, Ruegg C. Modulation of cdk2, cyclin D1, p16INK4a, p21WAF and p27Kip1 expression in endothelial cells by TNF/IFN gamma. Anticancer Res 2002;22:3159-3163.
    • (2002) Anticancer Res , vol.22 , pp. 3159-3163
    • Dormond, O.1    Lejeune, F.J.2    Ruegg, C.3
  • 34
    • 0037462671 scopus 로고    scopus 로고
    • Src kinase mediates phosphatidylinositol 3-kinase/Akt-dependent rapid endothelial nitric-oxide synthase activation by estrogen
    • Haynes MP, Li L, Sinha D, et al. Src kinase mediates phosphatidylinositol 3-kinase/Akt-dependent rapid endothelial nitric-oxide synthase activation by estrogen. J Biol Chem 2003;278:2118-2123.
    • (2003) J Biol Chem , vol.278 , pp. 2118-2123
    • Haynes, M.P.1    Li, L.2    Sinha, D.3
  • 35
    • 0034006420 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase: Correlation with histologic grade, lymph node status and estrogen receptor expression in human breast cancer
    • Martin JH, Begum S, Alalami O, et al. Endothelial nitric oxide synthase: correlation with histologic grade, lymph node status and estrogen receptor expression in human breast cancer. Tumour Biol 2000;21:90-97.
    • (2000) Tumour Biol , vol.21 , pp. 90-97
    • Martin, J.H.1    Begum, S.2    Alalami, O.3
  • 36
    • 0029658659 scopus 로고    scopus 로고
    • Simultaneous expression of nitric oxide synthase and estrogen receptor in human breast cancer cell lines
    • Zeillinger R, Tantscher E, Schneeberger C, et al. Simultaneous expression of nitric oxide synthase and estrogen receptor in human breast cancer cell lines. Breast Cancer Res Treat 1996;40:205-207.
    • (1996) Breast Cancer Res Treat , vol.40 , pp. 205-207
    • Zeillinger, R.1    Tantscher, E.2    Schneeberger, C.3
  • 37
    • 0037438835 scopus 로고    scopus 로고
    • Inhibition of heat shock protein 90 (hsp90) in proliferating endothelial cells uncouples endothelial nitric oxide synthase activity
    • Ou J, Ou Z, Ackerman AW, et al. Inhibition of heat shock protein 90 (hsp90) in proliferating endothelial cells uncouples endothelial nitric oxide synthase activity. Free Radic Biol Med 2003;34:269-276.
    • (2003) Free Radic Biol Med , vol.34 , pp. 269-276
    • Ou, J.1    Ou, Z.2    Ackerman, A.W.3
  • 38
    • 0029800347 scopus 로고    scopus 로고
    • Presence of endothelial calcium-dependent nitric oxide synthase in breast apocrine metaplasia
    • Tschugguel W, Knogler W, Czerwenka K, et al. Presence of endothelial calcium-dependent nitric oxide synthase in breast apocrine metaplasia. Br J Cancer 1996;74:1423-1426.
    • (1996) Br J Cancer , vol.74 , pp. 1423-1426
    • Tschugguel, W.1    Knogler, W.2    Czerwenka, K.3
  • 39
    • 0032909569 scopus 로고    scopus 로고
    • Nitric oxide sensitizes ovarian tumor cells to Fas-induced apoptosis
    • Garban HJ, Bonavida B. Nitric oxide sensitizes ovarian tumor cells to Fas-induced apoptosis. Gynecol Oncol 1999;73:257-264.
    • (1999) Gynecol Oncol , vol.73 , pp. 257-264
    • Garban, H.J.1    Bonavida, B.2
  • 40
    • 0035569074 scopus 로고    scopus 로고
    • Progesterone induces apoptosis in malignant mesothelioma cells
    • Horita K, Inase N, Miyake S, et al. Progesterone induces apoptosis in malignant mesothelioma cells. Anticancer Res 2001;21:3871-3874.
    • (2001) Anticancer Res , vol.21 , pp. 3871-3874
    • Horita, K.1    Inase, N.2    Miyake, S.3
  • 41
    • 0033663933 scopus 로고    scopus 로고
    • Hormonal regulation of apoptosis in breast cells and tissues
    • Gompel A, Somai S, Chaouat M, et al. Hormonal regulation of apoptosis in breast cells and tissues. Steroids 2000;65:593-598.
    • (2000) Steroids , vol.65 , pp. 593-598
    • Gompel, A.1    Somai, S.2    Chaouat, M.3
  • 42
    • 0032839396 scopus 로고    scopus 로고
    • Maintenance treatment with medroxyprogesterone acetate in patients with advanced breast cancer responding to chemotherapy: Results of a randomized trial
    • Essen Breast Cancer Study Group
    • Kloke O, Klaassen U, Oberhoff C, et al. Maintenance treatment with medroxyprogesterone acetate in patients with advanced breast cancer responding to chemotherapy: results of a randomized trial. Essen Breast Cancer Study Group. Breast Cancer Res Treat 1999;55:51-59.
    • (1999) Breast Cancer Res Treat , vol.55 , pp. 51-59
    • Kloke, O.1    Klaassen, U.2    Oberhoff, C.3
  • 43
    • 17844390913 scopus 로고    scopus 로고
    • Adjuvant high-dose medroxyprogesterone acetate for early breast cancer: 13 Years update in a multicentre randomized trial
    • Focan C, Beauduin M, Salamon E, et al. Adjuvant high-dose medroxyprogesterone acetate for early breast cancer: 13 years update in a multicentre randomized trial. Br J Cancer 2001;85:1-8.
    • (2001) Br J Cancer , vol.85 , pp. 1-8
    • Focan, C.1    Beauduin, M.2    Salamon, E.3
  • 44
    • 0036754196 scopus 로고    scopus 로고
    • The effect of continuous combined 17beta-oestradiol and dihydrodydrogesterone on apoptotic cell death and proliferation of human breast cancer cells in vitro
    • Franke HR, Vermes I. The effect of continuous combined 17beta-oestradiol and dihydrodydrogesterone on apoptotic cell death and proliferation of human breast cancer cells in vitro. Eur J Cancer 2002;38(Suppl 6):S69-S70.
    • (2002) Eur J Cancer , vol.38 , Issue.SUPPL. 6
    • Franke, H.R.1    Vermes, I.2


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