Nitric oxide sensitizes ovarian tumor cells to Fas-induced apoptosis

Gynecologic Oncology

Volumn 73, Issue 2, 1999, Pages 257-264

  Garbán, Hermes J ^a   Bonavida, Benjamin ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis; Fas; Nitric oxide; Nitric oxide synthase; Ovarian carcinoma; Tumor immunobiology

Indexed keywords

COMPLEMENTARY DNA; CYTOKINE; FAS ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 1BETA; MESSENGER RNA; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; NITROPRUSSIDE SODIUM; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION REGULATION; GYNECOLOGIC CANCER; HUMAN; HUMAN CELL; OVARY TUMOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL;

EID: 0032909569     PISSN: 00908258     EISSN: None     Source Type: Journal    
DOI: 10.1006/gyno.1999.5374     Document Type: Article

References (34)

1. Leithauser F, Dhein J, Mechtersheimer G, Koretz K, Bruderlein S, Henne C, Schmidt A, Debatin KM, Krammer PH, Moller P: Constitutive and induced expression of APO-1, a new member of the nerve growth factor/ tumor necrosis factor receptor superfamily, in normal and neoplastic cells. Lab Invest 69:415-429, 1993
2. Foghi A, Ravandi A, Teerds KJ, Van Der Donk H, Kuksis A, Dorrington J: Fas-induced apoptosis in rat thecal/interstitial cells signals through sphingomyelin-ceramide pathway. Endocrinology 139:2041-2047, 1998
3. Quirk SM, Cowan RG, Joshi SG, Henrikson KP: Fas antigen-mediated apoptosis in human granulosa/luteal cells. Biol Reprod 52:279-287, 1995
4. Wakahara Y, Nawa A, Okamoto T, Hayakawa A, Kikkawa F, Suganama N, Wakahara F, Tomoda Y: Combination effect of anti-Fas antibody and chemotherapeutic drugs in ovarian cancer cells in vitro. Oncology 54:48-54, 1997
5. Cai Z, Stancou R, Korner M, Chouaib S: Impairment of Fas-antigen expression in adriamycin-resistant but not TNF-resistant MCF7 tumor cells. Int J Cancer 68:535-546, 1996
6. Yonehara S, Ishii A, Yonehara M: A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J Exp Med 169:1747-1756, 1989
7. Itoh N, Yonehara S, Ishii A, Yonehara M, Mizushima S, Sameshima M, Hase A, Seto Y, Nagata S: The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66:233-243, 1991
8. Morimoto H, Yonehara S, Bonavida B: Overcoming tumor necrosis factor and drug resistance of human tumor cell lines by combination treatment with anti-Fas antibody and drugs or toxins. Cancer Res 53:2591-2596, 1993
9. Schall TJ, Lewis M, Koller KJ, Lee A, Rice GC, Wong GHW, Gatanaga T, Granger GA, Lentz R, Raab H, Kohr WJ, Goeddel DV: Molecular cloning and expression of a receptor for human tumor necrosis factor. Cell 61:361-370, 1990
10. Sherman PA, Laubach VE, Reep BR, Wood ER: Purification and cDNA sequence of an inducible nitric oxide synthase from a human tumor cell line. Biochemistry 32:11600-11605, 1993
11. Geller DA, Nussler AK, Di Silvio M, Lowenstein CJ, Shapiro RA, Wang SC, Simmons RL, Billiar TR: Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes. Proc Natl Acad Sci USA 90:522-526, 1993
12. Hokari A, Zeniya M, Esumi H: Cloning and functional expression of human inducible nitric oxide synthase (NOS) cDNA from a glioblastoma cell line A-172. J Biochem (Tokyo) 116:575-581, 1994
13. 15N]nitrate in biological fluids. Anal Biochem 126:131-138, 1982
14. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254, 1976
15. McGahon AJ, Martin SJ, Bissonnette RP, Mahboubi A, Shi Y, Mogil RJ, Nishioka WK, Geen DR: The end of the (cell) line: methods for the study of apoptosis in vitro., in Schwartz LM, Osborne BA (eds): Cell Death, San Diego, CA, Academic Press, 1995, Vol 46, pp 153-185.
16. Lowenstein CJ, Dinerman JL, Snyder SH: Nitric oxide: a physiologic messenger. Ann Intern Med 120:227-237, 1994
17. Billiar TR: Nitric oxide. Novel biology with clinical relevance. Ann Surg 221:339-349, 1995
18. Genaro AM, Hortelano S, Alvarez A, Martinez C, Bosca L: Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels. J Clin Invest 95: 1884-1890, 1995
19. Beauvais F, Michel L, Dubertret L: The nitric oxide donors, azide and hydroxylamine, inhibit the programmed cell death of cytokine-deprived human eosinophils. FEBS Lett 361:229-232, 1995
20. Chun SY, Eisenhauer KM, Kubo M, Hsueh AJ: Interleukin-1 beta suppresses apoptosis in rat ovarian follicles by increasing nitric oxide production. Endocrinology 136:3120-3127, 1995
21. Mannick JB, Asano K, Izumi K, Kieff E, Stamler JS: Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation. Cell 79:1137-1146, 1994
22. Hebestreit H, Dibbert B, Balatti I, Braun D, Schapowal A, Blaser K, Simon HU: Disruption of fas receptor signaling by nitric oxide in eosinophils. J Exp Med 187:415-425, 1998
23. Dimmeler S, Haendeler J, Nehls M, Zeiher AM: Suppression of apoptosis by nitric oxide via inhibition of interleukin-1 beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)- 32-like proteases. J Exp Med 185:601-607, 1997
24. Kim YM, Talanian RV, Billiar TR: Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms. J Biol Chem 272:31138-31148, 1997
25. Mannick JB, Miao XQ, Stamler JS: Nitric oxide inhibits Fas-induced apoptosis. J Biol Chem 272:24125-24128, 1997
26. Chlichlia K, Peter ME, Rocha M, Scaffidi C, Bucur M, Krammer PH, Schirrmacher V, Umansky V: Caspase activation is required for nitric oxide-mediated, CD95(APO- 1/Fas)-dependent and independent apoptosis in human neoplastic lymphoid cells. Blood 91:4311-4320, 1998
27. Nussler AK, Di Silvio M, Billiar TR, Hoffman RA, Geller DA, Selby R, Madariaga J, Simmons RL: Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin. J Exp Med 176:261-264, 1992
28. Thomsen LL, Lawton FG, Knowles RG, Beesley JE, Riveros-Moreno V, Moncada S: Nitric oxide synthase activity in human gynecological cancer. Cancer Res 54:1352-1354, 1994
29. Fukuo K, Hata S, Suhara T, Nakahashi T, Shinto Y, Tsujimoto Y, Morimoto S, Ogihara T: Nitric oxide induces upregulation of Fas and apoptosis in vascular smooth muscle. Hypertension 27:823-826, 1996
30. Stassi G, Maria RD, Trucco G, Rudert W, Testi R, Galluzzo A, Giordano C, Trucco M: Nitric oxide primes pancreatic beta cells for Fas-mediated destruction in insulin-dependent diabetes mellitus. J Exp Med 186:1193-1200, 1997
31. Andrew PJ, Harant H, Lindley IJ: Nitric oxide regulates IL-8 expression in melanoma cells at the transcriptional level. Biochem Biophys Res Commun 214:949-956, 1995
32. Remick DG, Villarete L: Regulation of cytokine gene expression by reactive oxygen and reactive nitrogen intermediates. J Leukocyte Biol 59:471-475, 1996
33. Tabuchi A, Sano K, Oh E, Tsuchiya T, Tsuda M: Modulation of AP-1 activity by nitric oxide (NO) in vitro: NO-mediated modulation of AP-1. FEBS Lett 351:123-127, 1994
34. Tabuchi K, Shiraishi T, Toda K, Kawaguchi S: Expression of apoptosis-related gene products in human brain tumors and apoptosis-inducing therapy. Nippon Rinsho 54:1922-1928, 1996