Epstein-Barr virus-associated lymphoproliferative disease occurring in a patient with sarcoidosis treated by methotrexate and methylprednisolone

European Journal of Haematology

Volumn 69, Issue 4, 2002, Pages 248-253

  Theate, Ivan ^a   Michaux, L ^b   Dardenne, S ^a   Guiot, Y ^a   Briere J ^d   Emile, F J ^e   Fabiani, B ^f   Detry, R ^a   Gaulard, P ^c  

^a CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^b Department of Haematology ^*  (Belgium)

^c HENRI MONDOR HOSPITAL   (France)

^d SAINT LOUIS HOSPITAL   (France)

^e HÔPITAL PAUL BROUSSE   (France)

^f CENTRE HOSPITALIER DU MANS   (France)

Author keywords

Epstein Barr virus; Immunosuppression; Lymphoproliferative disorder; Methotrexate; Sarcoidosis

Indexed keywords

CORTISONE; CYCLOPHOSPHAMIDE; CYTARABINE; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; MERCAPTOPURINE; METHOTREXATE; METHYLPREDNISOLONE; VINCRISTINE;

ADULT; ANUS FISTULA; ARTICLE; B LYMPHOCYTE; CASE REPORT; CELL INFILTRATION; CLINICAL FEATURE; CONNECTIVE TISSUE DISEASE; DISEASE DURATION; EPSTEIN BARR VIRUS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNE DEFICIENCY; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOID CELL; LYMPHOPROLIFERATIVE DISEASE; MALE; MEDICAL EXAMINATION; NECROSIS; ONSET AGE; PERIANAL ABSCESS; PRIORITY JOURNAL; RECTUM TUMOR; SARCOIDOSIS; SYSTEMIC DISEASE; TREATMENT OUTCOME; TUMOR REGRESSION;

ANTI-INFLAMMATORY AGENTS; EPSTEIN-BARR VIRUS INFECTIONS; HERPESVIRUS 4, HUMAN; HUMANS; IMMUNOSUPPRESSION; IMMUNOSUPPRESSIVE AGENTS; LYMPHOPROLIFERATIVE DISORDERS; MALE; METHOTREXATE; METHYLPREDNISOLONE; MIDDLE AGED; SARCOIDOSIS, PULMONARY;

EID: 18744380650     PISSN: 09024441     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0609.2002.02748.x     Document Type: Article

References (47)

1. Brincker H. The incidence of malignant tumors in patients with respiratory sarcoidosis. Br J Cancer 1974;29:247-251.
2. Brincker H. The sarcoidosis-lymphoma syndrome. Br J Cancer 1986;54:467-473.
3. Reich JM, Mulloly JP, Johnson RE. Linkage analysis of malignancy-associated sarcoidosis. Chest 1995;107:605-613.
4. Seersholm N, Vestbo J, Viskum K. Risk of malignant neoplasms in patients with pulmonary sarcoidosis. Thorax 1997;52:892-894.
5. Romer FK, Hommelgaard P, Schou G. Sarcoidosis and cancer revisited: A long-term follow-up study of 555 Danish sarcoidosis patients. Eur Respir J 1998;12:906-912.
6. Brennan NJ, Fennelly JJ, Towers RP, Fitzgerald MX. Sarcoidosis and lymphoma in the same patient. Postgrad Med J 1983;59:581-585.
7. Masuda R, Toyoshima H, Bandou T, Isoyama T, Matsui Y, Takemura T. Malignant lymphoma of the stomach associated with systemic sarcoidosis. Cancer 1992;70:2592-2596.
8. Maingene C, Picard O, Audouin J, Le Tourneau A, Jagueux M, Diebold J. An unusual case of mycosis fungoides presenting as sarcoidosis or granulomatous mycosis fungoides. Am J Clin Pathol 1993;99:82-86.
9. Harada H, Shijubo N, Katoh S, Satoh M, Abe S. Malignant T cell lymphoma associated with sarcoidosis. Sarcoidosis 1994;11:132-134.
10. Ryan PJ, Stableforth P, MacLeod DT. Coexisting conjunctival non-Hodgkin's lymphoma and pulmonary sarcoidosis. Thorax 1996;51:444-445.
11. Karakantza M, Matutes E, MacLennan K, O'Connor NT, Srivastava PC, Catovsky D. Association between sarcoidosis and lymphoma revisited. J Clin Pathol 1996;49:208-212.
12. Askling J, Grunewald J, Eklund A, Hillerdal G, Ekbom A. Increased risk of cancer following sarcoidosis. Am J Respir Crit Care Med 1999;160:1668-1672.
13. Kobayashi H, Kato Y, Hakamada M, et al. Malignant lymphoma of the bone associated with systemic sarcoidosis. Intern Med 2001;40:435-438.
14. Donnelly S, Amos R, Norton AJ. A patient with rheumatoid arthritis and lymphoma. Br J Rheumatol 1992;31:107-112.
15. Kingsmore SF, Hall BD, Allen WB, Ryce JR, Caldwell DS. Association of methotrexate, rheumatoid arthritis and lymphoma: Report of two cases and literature review. J Rheumatol 1992;19:1462-1465.
16. Gridley G, McLaughlin JK, Ekbom A, et al. Incidence of cancer among patients with rheumatoid arthritis. J Natl Cancer Inst 1993;85:307-311.
17. Taillan B, Garnier G, Castanet J, Ferrari E, Pesce A, Dujardin P. Lymphoma developing in a patient with rheumatoid arthritis taking methotrexate. Clin Rheumatol 1993;12:93-94.
18. Kamel OW, van de Rijn M, Lebrun DP, Weiss LM, Warnke RA, Dorfman RF. Lymphoid neoplasms in patients with rheumatoid arthritis and dermatomyositis: Frequency of Epstein-Barr virus and other features associated with immunosuppression. Hum Pathol 1994;25:638-643.
19. Usman AR, Yunus MB. Non-Hodgkin's lymphoma in patients with rheumatoid arthritis treated with low-dose methotrexate. J Rheumatol 1996;23:1095-1097.
20. Salloum E, Cooper DL, Howe G, et al. Spontaneous regression of lymphoproliferative disorders in patients treated with methotrexate for rheumatoid arthritis and other rheumatic diseases. J Clin Oncol 1996;14:1943-1949.
21. Bachman TR, Sawitzke AD, Perkins SL, Ward JH, Cannon GW. Methotrexate-associated lymphoma in patients with rheumatoid arthritis. Arthritis Rheum 1996;2:325-329.
22. van de Rijn M, Cleary ML, Variakojis D, Warnke RA, Chang PP, Kamel OW. Epstein-Barr virus clonality in lymphomas occurring in patients with rheumatoid arthritis. Arthritis Rheum 1996;39:638-642.
23. Padeh S, Sharon N, Schiby G, Rechavi G, Passwell JH. Hodgkin's lymphoma in systemic onset juvenile rheumatoid arthritis after treatment with low dose methotrexate. J Rheumatol 1997;24:2035-2037.
24. Georgescu L, Quinn GE, Schwartzmann S, Paget SA. Lymphoma in patients with rheumatoid arthritis: Association with disease state or methotrexate treatment. Semin Arthritis Rheum 1997;26:794-804.
25. Bologna C, Picot MC, Jorgensen C, Viu P, Verdier R, Sany J. Study of eight cases of cancer in 246 rheumatoid arthritis patients treated with methotrexate. Ann Rheum Dis 1997;56:97-102.
26. Paul C, Le Tourneau A, Cayuela JM, et al. Epstein-Barr virus associated lymphoproliferative disease during methotrexate therapy therapy for psoriasis. Arch Dermatol 1997;133:867-871.
27. Kamel OW, Holly EA, van de Rijn M, Lele C, Sah A. A population-based, case control study of non-Hodgkin's lymphoma in patients with rheumatoid arthritis. J Rheumatol 1999;26:1676-1680.
28. Menke DM, Griesser H, Moder KG, et al. Lymphomas in patients with connective tissue disease. Comparison of p53 protein expression and latent EBV infection in patients immunosuppressed and not immunosuppressed with methotrexate. Am J Clin Pathol 2000;113:212-218.
29. Guiot Y, Rahier J. The effects of varying key steps in the non-radioactive in situ hybridization protocol: A quantitative study. Histochem J 1995;27:60-68.
30. Theodorou I, Delfau-Larue MH, Bigorgne C, et al. Cutaneous T-cell receptor γ gene rearrangement by polymerase chain reaction and denaturing gradient gel electrophoresis. Blood 1995;86:305-310.
31. Brincker H. Coexistence of sarcoidosis and malignant disease: Causality or coincidence. Sarcoidosis 1989;6:31-43.
32. Lower GE, Baughman RP. Prolonged use of methotrexate for sarcoidosis. Arch Intern Med 1995;155:846-851.
33. Shiroky JB, Frost A, Skelton JD, Haegaert DG, Newkirk MM, Neville C. Complications of immunosuppression associated with weekly low dose methotrexate. J Rheumatol 1991;18:1172-1175.
34. Kamel OW, van de Rijn M, Weiss LM, et al. Brief report: Reversible lymphomas associated with Epstein-Barr virus occurring during methotrexate therapy for rheumatoid arthritis and dermatomyositis. New Engl J Med 1993;328:1317-1321.
35. Ferracioli GF, Casatta L, Bartoli E, et al. Epstein-Barr virus-associated Hodgkin's lymphoma in a rheumatoid arthritis patient treated with methotrexate and cyclosporin A. Arthritis Rheum 1995;38:867-868.
36. Liote F, Pertuiset E, Cochaud-Priollet B, et al. Methotrexate related B lymphoproliferative disease in a patient with rheumatoid arthritis. Role of Epstein-Barr virus infection. J Rheumatol 1995;22:1174-1178.
37. Thomason RW, Craig FE, Banks PM, Sears DL, Myerson GE, Galley ML. Epstein-Barr virus and lymphoproliferation in methotrexate treated rheumatoid arthritis. Mod Pathol 1996;9:261-266.
38. Chevrel G, Berger F, Miossec P, et al. Hodgkin's disease and B-cell lymphoproliferation in rheumatoid arthritis patients treated with methotrexate. A kinetic study of lymph node changes. Arthritis Rheum 1999;42:1773-1776.
39. Nalesnik MA, Jaffe R, Starzl TE, et al. The pathology of post-transplant lymphoproliferative disorders occurring in the setting of cyclosporine A-prednisone immunosuppression. Am J Pathol 1988;133:173-192.
40. Mollers M, Aries SP, Dromann D, Mascher B, Braun J, Dalhoff K. Intracellular cytokine repertoire in different T cell subsets from patients with sarcoidosis. Thorax 2001;56:487-493.
41. Thomas PD, Hunninghake GW. Current concepts of the pathogenesis of sarcoidosis. Br J Cancer 1987;135:747-760.
42. Faro A. Interferon-alpha and its effects on post-transplant lymphoproliferative disorders. Springer Semin Immunopathol 1998;20:425-436.
43. Baecklund E, Ekbom A, Sparen P, Feltelius N, Klareskog L. Disease activity and risk of lymphoma in patients with rheumatoid arthritis: Nested case-control study. Br Med J 1998;317:180-181.
44. Stenger AA, Houtman PM, Bruyn GA, Egging HF, Pasma HR. Pneumocystis carinii pneumonia associated with low dose methotrexate treatment for rheumatoid arthritis. Scand J Rheumatol 1994;23:51-53.
45. Antonelli MAS, Moreland LW, Brick JE. Herpes zoster in patients with rheumatoid arthritis treated with weekly, low dose methotrexate. Am J Med 1991;90:295-296.
46. Rickinson AB, Lee SP, Steven NM. Cytotoxic T lymphocyte responses to Epstein-Barr virus. Curr Opin Immunol 1996;8:492-497.
47. Sullivan JL, Byron KS, Brewster FE, Baker SM, Ochs HD. X-linked lymphoproliferative syndrome. Natural history of the immunodeficiency. J Clin Invest 1983;71:1765-1778.