Interferon-α and its effects on post-transplant lymphoproliferative disorders

Springer Seminars in Immunopathology

Volumn 20, Issue 3-4, 1998, Pages 425-436

  Faro, Albert ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; LYMPHOTOXIN;

ADOLESCENT; ADULT; ARTICLE; B LYMPHOCYTE; CELLULAR IMMUNITY; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG ACTIVITY; EPSTEIN BARR VIRUS; FEMALE; GRAFT REJECTION; HELPER CELL; HUMAN; IMMUNE SYSTEM; IMMUNOREGULATION; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOPROLIFERATIVE DISEASE; MALE; PRIORITY JOURNAL; VIRUS CELL TRANSFORMATION;

EID: 0031795098     PISSN: 03444325     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00838053     Document Type: Article

References (55)

1. Abbas A, Lichtman A, Pober J (1997) Cytokines. In: Cellular and molecular immunology, 3rd edn. Saunders, Philadelphia, p 250
2. Aman MJ, Tretter T, Eisenbeis I, Bug G, Decker T, Aulitzky WE, Tilg H, Huber C, Peschel C (1996) Interferon-α stimulates production of inlerleukin-10 in activated CD4 T cells and monocytes. Blood 87 : 4731
3. Anthes JC, Zhan Z, Gilchrest H, Egan RW, Siegel MI, Billah MM (1995) Interferon-α down-regulates the interleukin-6 receptor in a human multiple myeloma cell line, U266. Biochem J 309 : 175
4. Beatty PR, Krams SM, Martinez OM (1997) Involvement of IL-10 in the autonomous growth of EBV-transformed B cell lines. J Immunol 158 : 4045
5. Benkerrou M, Durandy A, Fischer A (1993) Therapy for transplant related lymphoproliferative diseases. Hematol Oncol Clin North Am 7 : 467
6. Boyle GJ, Michaels MG, Webber SA, Knisely AS, Kurland G, Cipriani LA, Griffith BP, Fricker FJ (1997) Posttransplant lymphoproliferative disorders in pediatric thoracic organ recipients. J Pediatr 131 : 309
7. Brinkmann V, Heusser CH, Baer J, Kilchherr E, Erard F (1992) Interferon-α suppresses the capacity of T cells to help antibody production by human B cells. J Interferon Res 12 : 267
8. + T cells. J Exp Med 178 : 1655
9. Burdin N, Peronne C, Banchereau J, Rousset F (1993) Epstein-Barr virus transformation induces B lymphocytes to produce human interleukin 10. J Exp Med 177 : 295
10. Cantell K (1995) Development of antiviral therapy with alpha interferons: promises, false hopes and accomplishments. Ann Med 27 : 23
11. Chadburn A, Cesarman E, Knowles D (1997) Molecular pathology of posttransplant lymphoproliferative disorders. Semin Diagn Pathol 14 : 15
12. Coffman RL, Varkila K, Scott P, Chatelain R (1991) Role of cytokines in the differentiation of CD4T-cell subsets in vivo. Immunol Rev 123 : 189
13. De Waal Malefyt (1997) The role of type I interferons in the differentiation and function of Th1 and Th2 cells. Semin Oncol 24:S9-94
14. De Waal Malefyt R, Haanen J, Spits H, Roncarolo MG, Velde A te, Figdor C, Johnson K, Kastelein R, Yssel H, Vries JE de (1991) Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen specific human T cell proliferation by diminishing the antigen -presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J Exp Med 174 : 915
15. Delcayre AX, Lotz M, Lernhardt W (1993) Inhibition of Epstein-Barr virus mediated capping of CD21/CR2 by alpha interferon: immediate antiviral activity of IFN-α during the early phase of infection. J Virol 67 : 2918
16. Faro A, Kurland G, Michaels MG, Dickman PS, Greally PG, Spiehty KJ, Noyes BB, Boas SR, Fricker FJ, Armitage JM, Zeevi A (1996) Interferon-alpha affects the immune response in post-transplant lymphoproliferative disorder. Am J Respir Crit Care Med 153 : 1442
17. Garner JG, Hirsch MS, Schooley RT (1984) Prevention of Epstein-Barr virus induced B-cell outgrowth by interferon alpha. Infect Immun 43 : 920
18. Gutterman JU (1994) Cytokine therapeutics: lessons from interferon α. Proc Natl Acad Sci USA 91 : 1198
19. Hanto DW, Gajl-Peczalska KJ, Frizzera G, Arthur DC, Balfour HH Jr, McClain K, Simmons RL, Najarian JS (1983) Epstein-Barr virus (EBV) induced polyclonal and monoclonal B-cell lymphoproliferative diseases occurring after renal transplantation: clinical, pathologic, and virologic findings and implications for therapy. Ann Surg 198 : 356
20. Harris NL, Ferry JA, Swerdlow SH (1997) Posttransplant lymphoproliferative disorders: summary of society for hematopathology workshop. Semin Diagn Pathol 14 : 8
21. Ho M, Miller G, Atchison RW, Breinig MK, Dummer JS, Andiman W, Starzl TE, Eastman R, Griffith BP, Hardesty RL, Bahnson HT, Hakala TR, Rosenthal JT (1985) Epstein-Barr virus infections and DNA hybridization studies in posttransplant lymphoma and lymphoproliferative lesions: the role of primary infection. J Infect Dis 152 : 876
22. Hsieh CS, Heimberger AB, Gold JS, O'Garra AO, Murphy KM (1942) Differential regulation of T helper phenotype development by interleukins 4 and 10 in an αβ T-cell receptor transgenic system. Proc Natl Acad Sci USA 89 : 6065
23. + alpha beta-TCR transgenic T cells is macrophage dependent. Int Immunol 5 : 371
24. Ippoliti G, Martinelli L, Lorenzutti F, Incardona S, Negri M, Balduzzi P, Rovati B, Ascari E, Vigano M (1994) Posttransplant lymphoproliferative disease after heart transplantation on sandimmune therapy: treatment with Interferon alta-2b and intravenous immunoglobulin. Transplant Proc 26: 2660
25. Kane RE, Bunchman TE, Vogler C, Brems JJ (1992) Treatment of a B-cell lymphoproliferative disorder in a liver transplant patient with Interferon alfa and gamma globulin: a case report. Clin Transplant 6 : 154
26. Lindner DJ, Kalvakolanu DV, Borden EC (1997) Increasing effectiveness of interferon-α for malignancies. Semin Oncol 24 : S9-99
27. Lotz M, Tsoukas CD, Fong S, Dinarello CA, Carson DA, Vaughan JH (1985) Regulation of Epstein-Barr virus infection by recombinant interferons. Selected sensitivity to interferon-γ. Eur J Immunol 15 : 520
28. Lotz M, Tsoukas CD, Fong S, Dinarello CA, Carson DA, Vaughan JH (1986) Release of lymphokines after Epstein-Barr virus infection in vitro. J Immunol 136 : 3636
29. Mathur A, Kamat DM, Filipovich AH, Steinbuch M, Shapiro RS (1994) Immunoregulatory abnormalities in patients with Epstein-Barr virus-associated B cell lymphoproliferative disorders. Transplantation 57 : 1042
30. Menezes J, Patel P, Dussault H, Joncas J, Leibold W (1976) Effect of interferon on lymphocyte transformation and nuclear antigen production by Epstein-Barr virus. Nature 260 : 430
31. Morrison VA, Dunn DL, Manivel C, Gajl-Peczalska KJ, Peterson BA (1994) Clinical characteristics of post-transplant lymphoproliferative disorders. Am J Med 97 : 14
32. Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL (1986) Two types of murine helper T cell clone: definition according to profiles of lymphokine activities and secreted protein. J Immunol 136 : 2348
33. + T cells. Immunol Rev 123 : 209
34. Nalesnik MA (1991) Lymphoproliferative disease in organ transplant recipients. Springer Semin Immunopathol 13 : 199
35. Nalesnik MA, Zeevi A, Randhawa PS, Faro A, Spichty KJ, Demetris AJ, Fung JJ, Whiteside TL, Starzl TE. Cytokine mRNA profiles in Epstein-Barr virus-associated posttransplant lymphoproliferative disorders. Clin Transplant (in press)
36. Nalesnik MA, Rao AS, Furukawa H, Pham S, Zeevi A, Fung JJ, Klein G, Gritsch HA, Elder E, Whiteside TL, Starzl TE (1997) Autologous lymphokine activated killer cell therapy of Epstein-Barr virus positive and negative lymphoproliferative disorders arising in organ transplant recipients. Transplantation 63: 1200
37. Nemerow GR, Wolfert R, McNaughton ME, Cooper NR (1985) Identification and characterization of the Epstein-Barr virus receptor on human B lymphocytes and its relationship to the C3d complement receptor (CR2). J Virol 55 : 347
38. O'Brien S, Bernert RA, Logan JL, Lien YH (1997) Remission of posttransplant lymphoproliferative disorder after interferon alfa therapy. J Am Soc Nephrol 8 : 1483
39. Parronchi P, De Carli M, Manetti R, Simonelli C, Sampognaro S, Piccinni MP, Macchia D, Maggi E, Del Prete G, Romagnani S (1992) IL-4 and IFN (alpha and gamma) exert opposite regulatory effects on the development of cytolytic potential by Th1 or Th2 human T cell clones. J Immunol 149 : 2977
40. Parronchi P, Mohapatra S, Sampognaro S. Giannarini L, Wahn U, Chong P, Mohapatra S, Maggi E, Renz H, Romagnani S (1996) Effects of interferon-α on cytokine profile, T cell receptor repertoire and peptide reactivity of human allergen-specific T cells. Eur J Immunol 26 : 697
41. Pestka S (1997) The human interferon-α species and hybrid proteins. Semin Oncol 24 : S 9-4
42. Randhawa PS, Demetris AJ, Nalesnik MA (1994) The potential role of cytokines in the pathogenesis of Epstein-Barr virus associated post-transplant lymphoproliferative disease. Leuk Lymphoma 15 : 383
43. Rodriguez MA, Prinz WA, Sibbitt WL, Bankhurst AD, Williams RC Jr (1983) α-Interferon increases immunoglobulin production in cultured human mononuclear leukocytes. J Immunol 130: 1215
44. Schnyder-Candrian S, Strieter RM, Kunkel SL, Walz A (1995) Interferon-α and interferon-γ down-regulate the production of interleukin-8 and ENA-78 in human monocytes. J Leuk Biol 57 : 929
45. Schwabe M, Brini AT, Bosco MC, Rubboli F, Egawa M, Zhao J, Princler GL, Kung H (1994) Disruption by interferon-α of an autocrine interleukin-6 growth loop in IL-6 dependent U266 myeloma cells by homologous and heterologous down-regulation of the IL-6 receptor α- and β-chains. J Clin Invest 94 : 2317
46. Shapiro RS, Chauvenet A, McGuire W, Pearson A, Craft AW, McGlave P, Filipovich A (1988) Treatment of B cell lymphoproliferative disorder with interferon alpha and intravenous gamma globulin. N Engl J Med 318 : 1334
47. Sharp NA, Arrand JR, Clemens MJ (1989) Epstein-Barr virus replication in interferon treated cells. J Gen Virol 70 : 2521
48. Taga H, Taga K, Wang F, Chretien J, Tosato G (1995) Human and viral interleukin-10 in acute Epstein-Barr virus-induced infectious mononucleosis. J Infect Dis 171 : 1347
49. Taguchi Y, Purtilo DT, Okano M (1994) The effect of intravenous immunoglobulin and interferon-alpha on Epstein-Barr virus induced lymphoproliferative disorder in a liver transplant recipient. Transplantation 57: 1813
50. Tanner J, Weis J, Fearon D, Whang Y, Kieff E (1987) Epstein-Barr virus gp350/220 binding to the B lymphocyte C3d receptor mediates adsorption, capping, and endocytosis. Cell 50 : 203
51. Tosato G, Jones K, Breinig MK, McWilliams P, McKnight JLC (1993) Interleukin-6 production in post-transplant lymphoproliferative disease. J Clin Invest 91 : 2806
52. Trigg ME, Alarcon P de, Rumelhart S, Holida M, Gilier R (1989) α-Interferon therapy for lymphoproliferative disorders developing in two children following bone marrow transplants. J Biol Respir Modif 8 : 603
53. Trinchieri G, Wysocka M, D'Andrea A, Rengaraju M, Aste-Amezaga M, Kubin M, Valiante NM, Chehimi J (1992) Natural killer cell stimulatory factor (NKSF) or ituerleukin-12 is a key regulator of immune response and inflammation. Prog Growth Factor Res 4 : 355
54. Viscomi GC, Grimaldi M, Palazzini E, Silvestri S (1995) Human leukocyte interferon alpha: structure, pharmacology, and therapeutic applications. Medicinal Res Reviews 15 : 445
55. Wenner CA, Guler ML, Macatonia SE, O'Garra A, Murphy KM (1996) Role of IFN-gamma and IFN-alpha in IL-12 induced T helper cell-1 development. J Immunol 156 : 1442