Effect of ZVAD-fmk on hepatocyte apoptosis after bile duct ligation in rat

World Journal of Gastroenterology

Volumn 11, Issue 15, 2005, Pages 2330-2333

  Sheen Chen, Shyr Ming ^a   Ho, Hsin Tsung ^b   Chen, Wei Jen ^a   Eng, Hock Liew ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b MACKAY MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Apoptosis; Obstructive jaundice; ZFA; ZVAD fmk

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; DIMETHYL SULFOXIDE; SODIUM CHLORIDE; BENZYLOXYCARBONYLVALYL ALANYL ASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYL-ALANYL-ASPARTYL FLUOROMETHYL KETONE; CYSTEINE PROTEINASE INHIBITOR; PEPTIDE CHLOROMETHYL KETONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BILE DUCT LIGATION; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; HISTOPATHOLOGY; LIVER CELL; MALE; NICK END LABELING; NONHUMAN; POSTOPERATIVE PERIOD; RAT; RAT STRAIN; STATISTICAL SIGNIFICANCE; SURGICAL TECHNIQUE; ANIMAL; COMMON BILE DUCT; DRUG EFFECT; LIGATION; OBSTRUCTIVE JAUNDICE; PATHOLOGY; SPRAGUE DAWLEY RAT;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; CHOLESTASIS, EXTRAHEPATIC; COMMON BILE DUCT; CYSTEINE PROTEINASE INHIBITORS; HEPATOCYTES; IN SITU NICK-END LABELING; LIGATION; MALE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 18744364714     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i15.2330     Document Type: Article

References (33)

1. Kerr JF, Wyllie AH, Currie AR. Apoptosis: a basic biology phenomenon with wide-ranging implication in tissue kinetics. Br J Cancer 1972; 26: 239-257
2. Allen RT, Hunter WJ III, Agrawae DK. Morphological and biochemical characterization and analysis of apoptosis. J Pharmacol Toxical Meth 1997; 37: 215-228
3. Cohen GM. Caspases: The executioners of apoptosis. Biochem J 1997; 326: 1-16
4. Seiger CP. Anthranoid laxative and colorectal cancer. Trends Pharmacol Sci 1992; 13: 229-231
5. Branconnier RJ, Branconnier ME, Walshe TM, McCarthy C, Morse PA. Blocking the Ca(2+)-activated cytotoxic mechanisms of cholinergic neuronal death: a novel treatment strategy for Alzheimer's disease. Psychopharmacol Bull 1992; 28: 175-181
6. Trauner M, Meier PJ, Boyer JL. Molecular pathogenesis of cholestasis. N Engl J Med 1998; 339: 1217-1227
7. Miyoshi H, Rust C, Roberts PJ, Burgart LJ, Gores GJ. Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas. Gastroenterology 1999; 117: 669-677
8. Patel T, Bronk SF, Gotes GJ. Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes. J Clin Invest 1994; 94: 2183-2192
9. Rodrigues CM, Fan G, Ma X, Kren BT, Steer CJ. A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation. J Clin Invest 1998; 101: 2790-2799
10. Webster CR, Anwer MS. Cyclic adenosine monophosphate-mediated protection against bile acid-induced apoptosis in cultured rat hepatocyte. Hepatology 1998; 27: 1324-1331
11. Faubion WA, Guicciardi ME, Miyoshi H, Bronk SF, Roberts PJ, Svingen PA, Kaufmann SH, Gores GJ. Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas. J Clin Invest 1999; 103: 137-145
12. Benz C, Angermuller S, Tox U, Kloters-Plachky P, Riedel HD, Sauer P, Stremmel W, Stiehl A. Effect of tauroursodeoxycholic add on bile-acid-induced apoptosis and cytolysis in rat hepatocytes. J Hepatol 1998; 28: 99-106
13. Rodrigues CM, Fan G, Wong PY, Kren BT, Steer CJ. Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production. Mol Med 1998; 4: 165-178
14. Salvesen GS, Dixit V. Caspases: intracellular signaling by proteolysis. Cell 1997; 91: 443-446
15. Enari M, Sakahira H, Yokyoama H. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 1998; 391: 43-50
16. Behrns KE, Schrum LW, Que FG. Apoptosis: cell death by proteolytic scalpel. Surgery 1999; 126: 463-468
17. Los M, Van de Craen M, Penning LC, Schenk H, Westendorp M, Baeuerle PA, Droge W, Krammer PH, Fiers W, Schulze-Osthoff K. Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis. Nature 1995; 375: 81-83
18. Piguet PF, Vesin C, Donati Y, Barazzone C. TNF-induced enterocyte apoptosis and detachment in mice: induction of caspases and prevention by a caspase inhibitor, ZVAD-fmk. Lab Invest 1999; 79: 495-500
19. Farber A, Connors JP, Friedlander RM, Wagner RJ, Powell RJ, Cronenwett JL. A specific inhibitor of apoptosis decreases tissue injury after intestinal ischemia-reperfusion in mice. J Vasc Surg 1999; 30: 752-760
20. Daemen MA, van't Veer C, Denecker G, Heemskerk VH, Wolfs TG, Clauss M, Vandenabeele P, Buurman WA. Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation. J Clin Invest 1999; 104: 541-921
21. Sheen-Chen SM, Chau P, Harris HW. Obstructive jaundice alters Kupffer cell function independent of bacterial translocation. J Surg Res 1998; 80: 205-209
22. Sheen-Chen SM, Chen HS, Ho HT, Chen WJ, Sheen CC, Eng HL. Effect of bile acid replacement on endotoxin-induced tumor necrosis factor-alpha production in obstructive jaundice. World J Surg 2002; 26: 448-450
23. Sheen-Chen SM, Ho HT, Chen WJ, Eng HL, Wu CH. Obstructive jaundice alters CD44 expression in rat small intestine. Digestion 2002; 65: 112-117
24. Sheen-Chen SM, Chen HS, Ho HT, Sheen CC, Chen WJ, Eng HL. Obstructive jaundice alters LFA-1alpha expression in rat small intestine. Dig Dis Sci 2003; 48: 1165-1170
25. Sheen-Chen SM, Ho HT, Chen WJ, Eng HL. Obstructive jaundice alters proliferating cell nuclear antigen expression in rat small intestine. World J Surg 2003; 27: 1161-1164
26. Sheen-Chen SM, Hung KS, Ho HT, Chen WJ, Eng HL. Effect of glutamine and bile acid on hepatocyte apoptosis after bile duct ligation in the rat. World J Surg 2004; 28: 457-460
27. Trauner M, Meier PJ, Boyer JL. Molecular pathogenesis of cholestasis. N Engl J Med 1998; 339: 1217-1227
28. Benz C, Angermuller S, Tox U, Kloters-Plachky P, Riedel HD, Sauer P, Stremmel W, Stiehl A. Effect of tauroursodeoxycholic acid on bile-acid-induced apoptosis and cytolysis in rat hepatocytes. J Hepatol 1998; 28: 99-106
29. Faubion WA, Guicciardi ME, Miyoshi H. Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas. J Clin Invest 1999; 103: 137-145
30. Hurle JM. Cell death in developing systems. Methods Archiv Exp Pathol 1988; 13: 55-86
31. Mac Donald HR, Lees RK. Programmed cell death of autoreactive thymocytes. Nature 1990; 343: 642-644
32. Behrns KE, Schrum LW, Que FG. Apoptosis: cell death by proteolytic scalpel. Surgery 1999; 126: 463-468
33. Su C, Peng FK, Lui WY. Factors affecting morbidity and mortality in biliary tract surgery. World J Surg 1992; 16: 536-540