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Volumn 63, Issue 5, 2005, Pages 166-170

The mechanism and regulation of fat mobilization from adipose tissue: Desnutrin, a newly discovered lipolytic enzyme

Author keywords

Adipocytes; Cyclic AMP; Desnutrin; Diglycerides; Free fatty acids; Hormone sensitive; Lipase; Monoglycerides; Perilipin; Triglycerides

Indexed keywords

ADENYLATE CYCLASE; ADRENALIN; CATECHOLAMINE; CORTICOTROPIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIACYLGLYCEROL; FATTY ACID; GLUCAGON; HORMONE SENSITIVE LIPASE; INSULIN; LIPID BINDING PROTEIN; MONOACYLGLYCEROL; PROTEIN; PROTEIN ADIPOCYTE LIPID BINDING PROTEIN; PROTEIN ADIPONUTRIN; PROTEIN DESNUTRIN; PROTEIN PERILIPIN; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

EID: 18644374356     PISSN: 00296643     EISSN: None     Source Type: Journal    
DOI: 10.1301/nr.2005.may.166-170     Document Type: Review
Times cited : (12)

References (14)
  • 1
    • 8844255630 scopus 로고    scopus 로고
    • Free fatty acids in obesity and type 2 diabetes: Defining their role in the development of insulin resistance and β-cell function
    • Boden G, Shulman GI. Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and β-cell function. Eur J Clin Invest. 2002;32(suppl 3):14-23.
    • (2002) Eur J Clin Invest , vol.32 , Issue.3 SUPPL. , pp. 14-23
    • Boden, G.1    Shulman, G.I.2
  • 2
    • 0036725464 scopus 로고    scopus 로고
    • Interaction between free fatty acids and glucose metabolism
    • Boden G. Interaction between free fatty acids and glucose metabolism. Curr Opin Clin Nutr Metab Care. 2002;5:545-549.
    • (2002) Curr Opin Clin Nutr Metab Care , vol.5 , pp. 545-549
    • Boden, G.1
  • 3
    • 0033544869 scopus 로고    scopus 로고
    • A crucial role of sterol regulatory element-binding protein-1 in the regulation of lipogenic gene expression by polyunsaturated fatty acids
    • Yahagi N, Shimano H, Hasty AH, et al. A crucial role of sterol regulatory element-binding protein-1 in the regulation of lipogenic gene expression by polyunsaturated fatty acids. J Biol Chem. 1999;274:35840-35844
    • (1999) J Biol Chem , vol.274 , pp. 35840-35844
    • Yahagi, N.1    Shimano, H.2    Hasty, A.H.3
  • 4
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor
    • Tontonoz P, Hu E, Spiegelman BM. Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell. 1994;79:1147-1156.
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 5
    • 0036794551 scopus 로고    scopus 로고
    • Hormone-sensitive lipase: Control of intracellular tri-(di-)acylglycerol and cholesteryl ester hydrolysis
    • Kraemer FB, Shen WJ. Hormone-sensitive lipase: control of intracellular tri-(di-)acylglycerol and cholesteryl ester hydrolysis. J Lipid Res. 2002;43:1585-1594.
    • (2002) J Lipid Res , vol.43 , pp. 1585-1594
    • Kraemer, F.B.1    Shen, W.J.2
  • 6
    • 0030767295 scopus 로고    scopus 로고
    • CDNA cloning, tissue distribution and identification of the catalytic triad of monoglyceride lipase
    • Karlsson M, Contreras JA, Hellman U, Tornqvist H, Holm C. cDNA cloning, tissue distribution and identification of the catalytic triad of monoglyceride lipase. J Biol Chem. 1997;272:27218-27223.
    • (1997) J Biol Chem , vol.272 , pp. 27218-27223
    • Karlsson, M.1    Contreras, J.A.2    Hellman, U.3    Tornqvist, H.4    Holm, C.5
  • 7
    • 0037085450 scopus 로고    scopus 로고
    • Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis
    • Haemmerle G, Zimmermann R, Hayn M, et al. Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis. J Biol Chem. 2002;277:4806-4815.
    • (2002) J Biol Chem , vol.277 , pp. 4806-4815
    • Haemmerle, G.1    Zimmermann, R.2    Hayn, M.3
  • 8
    • 8744297386 scopus 로고    scopus 로고
    • Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: Ectopic expression of desnutrin increases triglyceride hydrolysis
    • Villena JA, Suheeta R, Sarkadi-Nagy E, Kim KH, Sul HS. Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis. J Biol Chem. 2004;279:47066-47075.
    • (2004) J Biol Chem , vol.279 , pp. 47066-47075
    • Villena, J.A.1    Suheeta, R.2    Sarkadi-Nagy, E.3    Kim, K.H.4    Sul, H.S.5
  • 9
    • 0035823621 scopus 로고    scopus 로고
    • Adiponutrin, a transmembrane protein corresponding to a novel diet- and obesity-linked mRNA expressed in the adipose lineage
    • Baulande S, Lasnier F, Lucas M, Pairault J. Adiponutrin, a transmembrane protein corresponding to a novel diet- and obesity-linked mRNA expressed in the adipose lineage. J Biol Chem. 2001;276:33336-33344.
    • (2001) J Biol Chem , vol.276 , pp. 33336-33344
    • Baulande, S.1    Lasnier, F.2    Lucas, M.3    Pairault, J.4
  • 10
    • 0031845136 scopus 로고    scopus 로고
    • Nutritional and hormonal regulation of enzymes of fat synthesis: Studies of fatty acid synthase and mitochondrial glycerol-3-phosphate acyltransferase gene transcription
    • Sul HS, Wang D. Nutritional and hormonal regulation of enzymes of fat synthesis: studies of fatty acid synthase and mitochondrial glycerol-3-phosphate acyltransferase gene transcription. Ann Rev Nutr. 1998;18:331-351.
    • (1998) Ann Rev Nutr. , vol.18 , pp. 331-351
    • Sul, H.S.1    Wang, D.2
  • 11
    • 12944335303 scopus 로고    scopus 로고
    • Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity
    • Osuga J, Ishibashi S, Oka T, et al. Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity. Proc Natl Acad Sci U S A. 2000;97:787-792.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 787-792
    • Osuga, J.1    Ishibashi, S.2    Oka, T.3
  • 12
    • 0025273134 scopus 로고
    • Hormone-sensitive lipase: A multipurpose enzyme in lipid metabolism
    • Yeaman SJ. Hormone-sensitive lipase: a multipurpose enzyme in lipid metabolism. Biochim Biophys Acta. 1990;1052:128-132.
    • (1990) Biochim Biophys Acta , vol.1052 , pp. 128-132
    • Yeaman, S.J.1
  • 13
    • 8844226709 scopus 로고    scopus 로고
    • Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase
    • Zimmerman R, Strauss JG, Haemmerle G, et al. Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Science. 2004;306:1383-1386.
    • (2004) Science , vol.306 , pp. 1383-1386
    • Zimmerman, R.1    Strauss, J.G.2    Haemmerle, G.3
  • 14
    • 10344262633 scopus 로고    scopus 로고
    • Identification, cloning, expression and purification of three novel human calcium-idependent phospholipase A2 family members possessing triacylglycerol transacylase activities
    • Jenkins CM, Mancuso DJ, Sims HF, Gibson B, Gross RW. Identification, cloning, expression and purification of three novel human calcium-idependent phospholipase A2 family members possessing triacylglycerol transacylase activities. J Biol Chem. 2004;279:48968-48975.
    • (2004) J Biol Chem , vol.279 , pp. 48968-48975
    • Jenkins, C.M.1    Mancuso, D.J.2    Sims, H.F.3    Gibson, B.4    Gross, R.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.