Pituitary adenylate cyclase activating polypepetide is expressed by developing rat Purkinje cells and decreases the number of cerebellar γ- amino butyric acid positive neurons in culture

Neuroscience Letters

Volumn 265, Issue 3, 1999, Pages 207-210

  Skoglösa, Ylva ^a   Patrone, Cesare ^a   Lindholm, Dan ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Amino butyric acid; Cerebellum; In situ hybridization; Pituitary adenylate cyclase activating polypeptide; Prenatal development; Primary neuronal cultures; Purkinje cells

Indexed keywords

4 AMINOBUTYRIC ACID; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR;

ANIMAL CELL; ARTICLE; BRAIN DEVELOPMENT; CELL COUNT; CELL FATE; CELL SURVIVAL; CEREBELLUM; EMBRYO DEVELOPMENT; GABAERGIC SYSTEM; IN SITU HYBRIDIZATION; NERVE CELL CULTURE; NONHUMAN; PRENATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURKINJE CELL; RAT; TISSUE DISTRIBUTION; TISSUE SPECIFICITY;

AGE FACTORS; ANIMALS; CELLS, CULTURED; CEREBELLUM; FETUS; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU HYBRIDIZATION; MEDULLA OBLONGATA; NEUROPEPTIDES; NEUROTRANSMITTER AGENTS; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; PITUITARY GLAND; PURKINJE CELLS; RATS; RATS, WISTAR; RNA, MESSENGER;

EID: 18544403039     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00250-5     Document Type: Article

References (20)

1. Altman J., Bayer S.A. Development of the Cerbellar System: in Relation to its Evolution, Structure, and Functions. 1997;CRC Press, Boca Raton, FL.
2. Arimura A., Somogyvari-Vigh A., Weill C., Fiore R.C., Tatsuno I., Bay V., Brenneman D.E. PACAP functions as a neurotrophic factor. Ann. N.Y. Acad. Sci. 739:1994;228-243.
3. Basille M., Gonzalez B.J., Leroux P., Jeandel L., Fournier A., Vaudry H. Localization and characterization of PACAP receptors in the rat cerebellum during development: evidence for a stimulatory effect of PACAP on immature cerebellar granule cells. Neuroscience. 57:1993;329-338.
4. D'Agata V., Cavallaro S., Stivala F., Canonico P.L. Tissue-specific and developmental expression of pituitary adenylate cyclase-activating polypeptide (PACAP) receptors in rat brain. Eur. J. Neurosci. 8:1996;310-318.
5. Gonzalez B.J., Leroux P., Basille M., Bodenant C., Vaudry H. Somatostatin and pituitary adenylate cyclase-activating polypeptide (PACAP): two neuropeptides potentially involved in the development of the rat cerebellum. Ann. Endocrinol. (Paris). 55:1994;243-247.
6. Hashimoto H., Nogi H., Mori K., Ohishi H., Shigemoto R., Yamamoto K., Matsuda T., Mizuno N., Nagata S., Baba A. Distribution of the mRNA for a pituitary adenylate cyclase-activating polypeptide receptor in the rat brain: an in situ hybridization study. J. Comp. Neurol. 371:1996;567-577.
7. Hashimoto H., Yamamoto K., Hagigara N., Ogawa N., Nishino A., Aino H., Nogi H., Imanishi K., Matsuda T., Baba A. cDNA cloning of a mouse pituitary adenylate cyclase-activating polypeptide receptor. Biochim. Biophys. Acta. 1281:1996;129-133.
8. Lindholm D., Castren E., Tsoulfas P., Kolbeck R., Berzaghi M., Leingartner A., et al. Neurotrophin-3 induced by tri-iodothyronine in cerebellar granule cells promotes Purkinje cell differentiation. J. Cell. Biol. 122:1993;443-450.
9. Lindholm D., Skoglösa Y., Takei N. Developmental regulation of pituitary adenylate cyclase activating polypeptide (PACAP) and its receptor 1 in rat brain: function of PACAP as a neurotrophic factor. Ann. N.Y. Acad. Sci. 865:1998;189-196.
10. Lu N., Zhou R., DiCicco B.E. Opposing mitogenic regulation by PACAP in sympathetic and cerebral cortical precursors correlates with differential expression of PACAP receptor (PAC1-R) isoforms. J. Neurosci. Res. 53:1998;651-662.
11. Nielsen H.S., Hannibal J., Fahrenkrug J. Expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the postnatal and adult rat cerebellar cortex. NeuroReport. 9:1998;2639-2642.
12. Ogi K., Kimura C., Onda H., Arimura A., Fujino M. Molecular cloning and characterization of cDNA for the precursor of rat pituitary adenylate cyclase activating polypeptide (PACAP). Biochem. Biophys. Res. Commun. 173:1990;1271-1279.
13. Paxinos G., Törk I., Tecott L.H., Valentino K.L. Atlas of the Developing Rat Brain. 1991;Academic Press, London.
14. Paxinos G., Watson C. The Rat Brain in Stereotaxic Co-ordinates. 4th Ed. 1998;Academic Press, San Diego, CA.
15. Skoglösa Y., Lewén A., Takei N., Hillered L., Lindholm D. Regulation of pituitary adenylate cyclase activating polypeptide and its receptor type1 after traumatic brain injury: comparison with brain-derived neurotrophic factor and the induction of neuronal cell death. Neuroscience. 1999;. in press.
16. Skoglösa Y., Takei N., Lindholm D. Distribution of Pituitary adenylate cyclase activating polypeptide mRNA in the developing rat brain. Mol. Brain Res. 90:1999;235-247.
17. Spengler D., Waeber C., Pantaloni C., Holsboer F., Bockaert J., Seeburg P.H., Journot L. Differential signal transduction by five splice variants of the PACAP receptor. Nature. 365:1993;170-175.
18. 2+ ionophore-induced apoptosis of cultured embryonic rat cortical neurons. Brain Res. 652:1994;65-70.
19. Villalba M., Bockaert J., Journot L. Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway. J. Neurosci. 17:1997;83-90.
20. Zirrgiebel U., Ohga Y., Carter B., Berninger B., Inagaki N., Thoenen H., Lindholm D. Characterization of TrkB receptor-mediated signaling pathways in rat cerebellar granule neurons: involvement of protein kinase C in neuronal survival. J. Neurochem. 65:1995;2241-2250.