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Volumn 5, Issue 1, 2005, Pages 63-73

Bile acids are toxic for isolated cardiac mitochondria: A possible cause for hepatic-derived cardiomyopathies?

Author keywords

Bile acids; Cardiac mitochondria; Cholestasis; Hepatic disease; Mitochondrial permeability transition

Indexed keywords

BILE ACID; CHENODEOXYCHOLIC ACID; DEOXYCHOLIC ACID; DEOXYCHOLIC ACID DERIVATIVE; GLYCOCHENODEOXYCHOLIC ACID; GLYCOURSODEOXYCHOLIC ACID; LITHOCHOLIC ACID; TAURODEOXYCHOLIC ACID; UNCLASSIFIED DRUG;

EID: 18544374442     PISSN: 15307905     EISSN: None     Source Type: Journal    
DOI: 10.1385/ct:5:1:063     Document Type: Article
Times cited : (40)

References (28)
  • 1
  • 2
    • 0032171253 scopus 로고    scopus 로고
    • The effect of idebenone, a coenzyme analogue, on hydrophobic bile acid toxicity to isolated rat hepatocytes and hepatic mitochondria
    • Shivaram, K.N., Winklhofer-Roob, B.M., Straka, M.S., Devereaux, M.W., Everson, G., Mierau, G.W., and Sokol, R.J. (1998). The effect of idebenone, a coenzyme analogue, on hydrophobic bile acid toxicity to isolated rat hepatocytes and hepatic mitochondria. Free Rad. Biol. Med. 25: 480-492.
    • (1998) Free Rad. Biol. Med. , vol.25 , pp. 480-492
    • Shivaram, K.N.1    Winklhofer-Roob, B.M.2    Straka, M.S.3    Devereaux, M.W.4    Everson, G.5    Mierau, G.W.6    Sokol, R.J.7
  • 3
    • 0031983188 scopus 로고    scopus 로고
    • Vitamin E reduces oxidant injury to mitochondria and the hepatotoxicity of taurochenodeoxycholic acid in the rat
    • Sokol, R.J., McKim, J.M., Goff, M.C., Ruyle, S.Z., Devereaux, M.W., Han, D., et al. (1998). Vitamin E reduces oxidant injury to mitochondria and the hepatotoxicity of taurochenodeoxycholic acid in the rat. Gastroenterology 114:164-174.
    • (1998) Gastroenterology , vol.114 , pp. 164-174
    • Sokol, R.J.1    McKim, J.M.2    Goff, M.C.3    Ruyle, S.Z.4    Devereaux, M.W.5    Han, D.6
  • 4
    • 0033985520 scopus 로고    scopus 로고
    • Mitochondrial membrane perturbations in cholestasis
    • Rodrigues, C.M.P. and Steer, C.J. (2000). Mitochondrial membrane perturbations in cholestasis. J. Hepatol. 32: 135-141.
    • (2000) J. Hepatol. , vol.32 , pp. 135-141
    • Rodrigues, C.M.P.1    Steer, C.J.2
  • 5
    • 0028091169 scopus 로고
    • Toxicity of bile acids on the electron transport chain of isolated rat liver mitochondria
    • Krahenbuhl, S., Talos, C., Fischer, S., and Reichen, J. (1994). Toxicity of bile acids on the electron transport chain of isolated rat liver mitochondria. Hepatology 19:471-479.
    • (1994) Hepatology , vol.19 , pp. 471-479
    • Krahenbuhl, S.1    Talos, C.2    Fischer, S.3    Reichen, J.4
  • 7
    • 0033852206 scopus 로고    scopus 로고
    • Bile acids affect liver mitochondrial bioenergetics: Possible relevance for cholestasis therapy
    • Rolo, AP., Oliveira, P.J., Moreno, A.J.M., and Palmeira, C.M. (2000). Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy. Toxicol. Sci. 57:177-185.
    • (2000) Toxicol. Sci. , vol.57 , pp. 177-185
    • Rolo, A.P.1    Oliveira, P.J.2    Moreno, A.J.M.3    Palmeira, C.M.4
  • 8
    • 0029116916 scopus 로고
    • The mitochondrial permeability transition
    • Zoratti, M. and Szabò, I. (1995). The mitochondrial permeability transition. Biochim. Biophy. Acta 1241:139-176.
    • (1995) Biochim. Biophy. Acta , vol.1241 , pp. 139-176
    • Zoratti, M.1    Szabò, I.2
  • 9
    • 0035917814 scopus 로고    scopus 로고
    • Mitochondrial permeability transition and oxidative stress
    • Kowaltowski, A.J., Castilho, R.F., and Vercesi, A.E. (2001). Mitochondrial permeability transition and oxidative stress. FEBS Lett. 495:12-15.
    • (2001) FEBS Lett. , vol.495 , pp. 12-15
    • Kowaltowski, A.J.1    Castilho, R.F.2    Vercesi, A.E.3
  • 10
    • 0034068601 scopus 로고    scopus 로고
    • Mitochondrial control of cell death
    • Kroemer, G. and Reed, J.C. (2000). Mitochondrial control of cell death. Nature Med. 6:513-519.
    • (2000) Nature Med. , vol.6 , pp. 513-519
    • Kroemer, G.1    Reed, J.C.2
  • 11
    • 0032504695 scopus 로고    scopus 로고
    • Induction of the mitochondrial permeability transition as a mechanism of liver injury during cholestasis: A potential role for mitochondrial proteases
    • Gores, G.J., Miyoshi, H., Botla, R., Aguilar, H.I., and Bronk, S.F. (1998). Induction of the mitochondrial permeability transition as a mechanism of liver injury during cholestasis: a potential role for mitochondrial proteases. Biochim. Biophys. Acta 1366:167-175.
    • (1998) Biochim. Biophys. Acta , vol.1366 , pp. 167-175
    • Gores, G.J.1    Miyoshi, H.2    Botla, R.3    Aguilar, H.I.4    Bronk, S.F.5
  • 12
    • 0035129976 scopus 로고    scopus 로고
    • Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition
    • Yerushalmi, B., Dahl, R., Devereaux, M.W., Gumpricht, E., and Sokol, R.J. (2001). Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition. Hepatology 33: 616-626.
    • (2001) Hepatology , vol.33 , pp. 616-626
    • Yerushalmi, B.1    Dahl, R.2    Devereaux, M.W.3    Gumpricht, E.4    Sokol, R.J.5
  • 13
    • 0002226575 scopus 로고
    • The heart in liver disease
    • (Bomzon, A. and Blendis, L.M., eds.). CRC: Boca Raton, FL
    • Lee, S.S. and Bomzon, A., (1990). The heart in liver disease, in Cardiovascular Complications of Liver Disease (Bomzon, A. and Blendis, L.M., eds.). CRC: Boca Raton, FL: pp. 81-102.
    • (1990) Cardiovascular Complications of Liver Disease , pp. 81-102
    • Lee, S.S.1    Bomzon, A.2
  • 14
    • 0036147087 scopus 로고    scopus 로고
    • Cirrhotic cardiomyopathy: A pathophysiological review of circulatory dysfunction in liver disease
    • Moller, S. and Henriksen, J.H. (2002). Cirrhotic cardiomyopathy: a pathophysiological review of circulatory dysfunction in liver disease. Heart 87:9-15.
    • (2002) Heart , vol.87 , pp. 9-15
    • Moller, S.1    Henriksen, J.H.2
  • 15
    • 0034057377 scopus 로고    scopus 로고
    • The effects of bile acids on β-adrenoceptors, fluidity, and the extent of lipid peroxidation in rat cardiac membranes
    • Gazawi, H., Ljubuncic, P., Cogan, U., Hochgraff, E., BenShachar, D., and Bomzon, A. (2000). The effects of bile acids on β-adrenoceptors, fluidity, and the extent of lipid peroxidation in rat cardiac membranes. Biochem. Pharmacol. 59:1623-1628.
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 1623-1628
    • Gazawi, H.1    Ljubuncic, P.2    Cogan, U.3    Hochgraff, E.4    Benshachar, D.5    Bomzon, A.6
  • 16
    • 0035054627 scopus 로고    scopus 로고
    • The bile acid taaurocholate impairs rat cardiomyocyte function: A proposed mechanism for intra-uterine fetal death in obstetric cholestasis
    • Williamson, C., Gorelik, J., Eaton, B.M., Lab, M., deSwiet, M., and Korchev, Y. (2001). The bile acid taaurocholate impairs rat cardiomyocyte function: a proposed mechanism for intra-uterine fetal death in obstetric cholestasis. Clin. Sci. 100:363-369.
    • (2001) Clin. Sci. , vol.100 , pp. 363-369
    • Williamson, C.1    Gorelik, J.2    Eaton, B.M.3    Lab, M.4    Deswiet, M.5    Korchev, Y.6
  • 17
    • 0036070550 scopus 로고    scopus 로고
    • Improved efficiency of hepatic mitochondrial function in rats with cholestasis induced by an acute dose of alfa-naphtylisothiocyanate
    • Rolo, A.P., Oliveira, P.J., Seiça, R., Santos, M.S., Moreno, A.J., and Palmeira, C.M. (2002). Improved efficiency of hepatic mitochondrial function in rats with cholestasis induced by an acute dose of alfa-naphtylisothiocyanate. Toxicol. Appl. Pharmacol. 182:20-26.
    • (2002) Toxicol. Appl. Pharmacol. , vol.182 , pp. 20-26
    • Rolo, A.P.1    Oliveira, P.J.2    Seiça, R.3    Santos, M.S.4    Moreno, A.J.5    Palmeira, C.M.6
  • 18
    • 0036092085 scopus 로고    scopus 로고
    • Disruption of mitochondrial calcium homeostasis after chronic α-naphthylisothiocyanate administration: Relevance for cholestasis
    • Rolo, A.P., Oliveira, P.J., Seiça, R., Santos, M.S., Moreno, A.J., and Palmeira, C.M. (2002). Disruption of mitochondrial calcium homeostasis after chronic α-naphthylisothiocyanate administration: relevance for cholestasis. J. Investig. Med. 50:193-200.
    • (2002) J. Investig. Med. , vol.50 , pp. 193-200
    • Rolo, A.P.1    Oliveira, P.J.2    Seiça, R.3    Santos, M.S.4    Moreno, A.J.5    Palmeira, C.M.6
  • 19
    • 0037454702 scopus 로고    scopus 로고
    • Reduction in cardiac mitochondrial calcium loading capacity is observable during α-napthylisothiocyanate-induced acute cholestasis: A clue for hepatic-derived cardiomyopathies?
    • Oliveira, P.J., Rolo, A.P., Seiça, R., Santos, M.S., Palmeira, C.M., and Moreno, A.J. (2003a). Reduction in cardiac mitochondrial calcium loading capacity is observable during α-napthylisothiocyanate-induced acute cholestasis: a clue for hepatic-derived cardiomyopathies? Biochim. Biophys. Acta 1637:39-45.
    • (2003) Biochim. Biophys. Acta , vol.1637 , pp. 39-45
    • Oliveira, P.J.1    Rolo, A.P.2    Seiça, R.3    Santos, M.S.4    Palmeira, C.M.5    Moreno, A.J.6
  • 20
    • 0037338705 scopus 로고    scopus 로고
    • Cardiac mitochondrial calcium loading capacity is severely affected after chronic cholestasis in Wistar rats
    • Oliveira, P.J., Rolo, A.P., Seica, R., Santos, M.S., Palmeira, C.M., and Moreno, A.J. (2003b). Cardiac mitochondrial calcium loading capacity is severely affected after chronic cholestasis in Wistar rats. J. Invest. Med. 51:86-94.
    • (2003) J. Invest. Med. , vol.51 , pp. 86-94
    • Oliveira, P.J.1    Rolo, A.P.2    Seica, R.3    Santos, M.S.4    Palmeira, C.M.5    Moreno, A.J.6
  • 21
    • 0030606673 scopus 로고    scopus 로고
    • Hepatic levels of bile acids in end-stage chronic cholestatic liver disease
    • Fischer, S., Beuers, U., Spengler, U., Zwiebel, F.M., and Koebe, H.-G. (1996). Hepatic levels of bile acids in end-stage chronic cholestatic liver disease. Clin. Chim. Acta 251:173-186.
    • (1996) Clin. Chim. Acta , vol.251 , pp. 173-186
    • Fischer, S.1    Beuers, U.2    Spengler, U.3    Zwiebel, F.M.4    Koebe, H.-G.5
  • 22
    • 1642342080 scopus 로고    scopus 로고
    • Principles of Laboratory Animal Care
    • No authors listed National Institutes of Health, Bethesda, MD
    • (No authors listed) (1996). Principles of Laboratory Animal Care. NIH publication No. 85-23. National Institutes of Health, Bethesda, MD.
    • (1996) NIH Publication No. 85-23
  • 23
    • 0034652094 scopus 로고    scopus 로고
    • Carvedilol inhibits the exogenous NADH dehydrogenase in rat heart mitochondria
    • Oliveira, P.J., Santos, D.L., and Moreno, A.J.M. (2000). Carvedilol inhibits the exogenous NADH dehydrogenase in rat heart mitochondria. Arch. Biochem. Biophys. 374: 279-285.
    • (2000) Arch. Biochem. Biophys. , vol.374 , pp. 279-285
    • Oliveira, P.J.1    Santos, D.L.2    Moreno, A.J.M.3
  • 24
    • 0018665167 scopus 로고
    • Membrane potential of mitochondria measured with an electrode sensitive to tetraphenyl phosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state
    • Kamo, N., Muratsugu, M., Hongoh, R., and Kobatake, Y. (1979). Membrane potential of mitochondria measured with an electrode sensitive to tetraphenyl phosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state. J. Membrane Biol. 49:105-121.
    • (1979) J. Membrane Biol. , vol.49 , pp. 105-121
    • Kamo, N.1    Muratsugu, M.2    Hongoh, R.3    Kobatake, Y.4
  • 25
    • 0024360271 scopus 로고
    • Cyclosporin a is a potent inhibitor of the inner membrane mitochondrial transition in liver mitochondria
    • Broekemeier, K.M., Dempsey, M.E., and Pfeiffer, D.R. (1989). Cyclosporin A is a potent inhibitor of the inner membrane mitochondrial transition in liver mitochondria. J. Biol. Chem. 264:7826-7830.
    • (1989) J. Biol. Chem. , vol.264 , pp. 7826-7830
    • Broekemeier, K.M.1    Dempsey, M.E.2    Pfeiffer, D.R.3
  • 26
    • 0014526250 scopus 로고
    • Conjugated and unconjugated serum bile acid levels in patients with hepatobiliary diseases
    • Makino, I., Nakagawa, S., and Mashimo, K. (1969). Conjugated and unconjugated serum bile acid levels in patients with hepatobiliary diseases. Gastroenterology 56:1033-1039.
    • (1969) Gastroenterology , vol.56 , pp. 1033-1039
    • Makino, I.1    Nakagawa, S.2    Mashimo, K.3
  • 27
    • 0000904366 scopus 로고
    • Metabolism of bile salts in cholestasis in humans
    • (Tavoloni, N. and Berk, P.D., eds.). Raven, New York
    • Ostrow, J.D. (1993). Metabolism of bile salts in cholestasis in humans, in Hepatic Transport and Bile Secretion: Physiology and Pathophysiology (Tavoloni, N. and Berk, P.D., eds.). Raven, New York: pp. 673-712.
    • (1993) Hepatic Transport and Bile Secretion: Physiology and Pathophysiology , pp. 673-712
    • Ostrow, J.D.1
  • 28
    • 0020459841 scopus 로고
    • Bile acid profiles of human serum and skin interstitial fluid and their relationship to pruritus studied by gas chromatography-mass spectrometry
    • Bartholomew, T.C., Summerfield, J.A., Billing, B.H., and Lawson, A.M. (1982). Bile acid profiles of human serum and skin interstitial fluid and their relationship to pruritus studied by gas chromatography-mass spectrometry. Clin. Sci. 63:65-73.
    • (1982) Clin. Sci. , vol.63 , pp. 65-73
    • Bartholomew, T.C.1    Summerfield, J.A.2    Billing, B.H.3    Lawson, A.M.4


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