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Volumn 10, Issue 9, 2002, Pages 2927-2932

Design, synthesis, and biological evaluation of a cephalosporin-monohydroguaiaretic acid prodrug activated by a monoclonal antibody-β-lactamase conjugate

(11) Hakimelahi, Gholam Hossein a,g Shia, Kak Shan a Pasdar, Manijeh b Hakimelahi, Shahram b Khalafi Nezhad, Ali c Soltani, Mohammad N c Mei, Nai Wen d Mei, Hui Ching e Saboury, Ali A f Rezaei Tavirani, Mostafa f Moosavi Movahedi, Ali A f,g

a INSTITUTE OF CHEMISTRY (Taiwan)

b UNIVERSITY OF ALBERTA (Canada)

c SHIRAZ UNIVERSITY (Iran)

d Co Wealth Medical Science and Biotechnology Inc ^* (Taiwan)

e CHINA MEDICAL UNIVERSITY (Taiwan)

f UNIVERSITY OF TEHRAN (Iran)

g TaiGen Biotechnology (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (3,4 DIMETHOXYPHENYL)DIMETHYL 4 [3 METHOXY 4 (7 PHENOXYACETAMIDO) (1 OXO) 3 CEPHEN 4 HYDROXYCARBONYL 3 METHOXYPHENYL]BUTANE; ANTINEOPLASTIC AGENT; BETA LACTAMASE; CEPHALOSPORIN DERIVATIVE; HYBRID PROTEIN; MONOCLONAL ANTIBODY; NORHYDROGUAIARETIC ACID; PRODRUG; PROTEIN DSFV3 BETA LACTAMASE; UNCLASSIFIED DRUG; ANTIBODY CONJUGATE; CANCER ANTIBODY; NORDIHYDROGUAIARETIC ACID;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CARCINOMA; CANCER CELL; COLON CANCER; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; EMBRYO CELL; FIBROBLAST; HUMAN; HUMAN CELL; IC 50; LEUKEMIA; LUNG CANCER; PANCREAS CANCER; PROTON NUCLEAR MAGNETIC RESONANCE; CELL CULTURE; CELL DIVISION; DRUG EFFECT; DRUG POTENTIATION; HYDROLYSIS; IMMUNOLOGY; METABOLISM; SYNTHESIS;

ANTIBODIES, NEOPLASM; ANTINEOPLASTIC AGENTS; BETA-LACTAMASES; CELL DIVISION; CEPHALOSPORINS; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; HUMANS; HYDROLYSIS; IMMUNOCONJUGATES; NORDIHYDROGUAIARETIC ACID; PRODRUGS; TUMOR CELLS, CULTURED;

EID: 18444395235 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/S0968-0896(02)00140-2 Document Type: Article

Times cited : (6)

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