Detection of DNA strand breaks and oxidized DNA bases at the single-cell level resulting from exposure to estradiol and hydroxylated metabolites

Environmental and Molecular Mutagenesis

Volumn 45, Issue 4, 2005, Pages 397-404

  Rajapakse, Nissanka ^a   Butterworth, Michael ^b   Kortenkamp, Andreas ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

17 estradiol; Chi square distribution; Comet assay; Genotoxicity; Hydroxylated estrogens

Indexed keywords

2 HYDROXY 17BETA ESTRADIOL; 4 HYDROXYESTRADIOL; CARCINOGEN; CATECHOL; DIMETHYL SULFOXIDE; DNA BASE; DNA FORMAMIDOPYRIMIDINE GLYCOSYLASE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; OXYGEN RADICAL; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL PROLIFERATION; CHI SQUARE DISTRIBUTION; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; ESTROGEN METABOLISM; GENE MUTATION; GENOMIC INSTABILITY; GENOTOXICITY; HUMAN; HUMAN CELL; HYDROXYLATION; LONG TERM EXPOSURE; METABOLITE; OXIDATION; OXIDATIVE STRESS;

CELL LINE, TUMOR; COMET ASSAY; DNA DAMAGE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGENS, CATECHOL; HUMANS; OXIDATION-REDUCTION;

MINK CELL FOCUS-FORMING VIRUS;

EID: 18444370889     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/em.20104     Document Type: Article

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