Two COOH-terminal truncated cytoplasmic forms of topoisomerase IIα in a VP-16-selected lung cancer cell line result from partial gene deletion and alternative splicing

Biochemistry

Volumn 36, Issue 19, 1997, Pages 5868-5877

  Yu, Qiang ^a   Mirski, Shelagh E L ^a   Sparks, Kathryn E ^a   Cole, Susan P C ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); ETOPOSIDE; GYRASE INHIBITOR; MESSENGER RNA; MUTANT PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; GENE DELETION; HUMAN; HUMAN CELL; LUNG CANCER; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING;

AMINO ACID SEQUENCE; BASE COMPOSITION; BASE SEQUENCE; BLOTTING, NORTHERN; CARCINOMA, SMALL CELL; CLONING, MOLECULAR; CYTOPLASM; DNA TOPOISOMERASES, TYPE II; ETOPOSIDE; GENE DELETION; HUMANS; LUNG NEOPLASMS; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; POLYMERASE CHAIN REACTION; RESTRICTION MAPPING; RNA, MESSENGER; RNA-DIRECTED DNA POLYMERASE; SEQUENCE ANALYSIS, DNA; TUMOR CELLS, CULTURED;

EID: 0030912109     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi962400y     Document Type: Article

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