Chemo-enzymatic synthesis of chiral fluorine-containing building blocks

Chimia

Volumn 58, Issue 3, 2004, Pages 104-107

  Blaauw, Richard H ^a   IJzendoorn, Denis R ^a   Cremers, Jozef G O ^b   Rutjes, Floris P J T ^b   Broxterman, Quirinus B ^c   Schoemaker, Hans E ^c  

^a CHIRALIX B V   (Netherlands)

^b RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^c DSM Pharmaceutical Products   (Netherlands)

Author keywords

Asymmetric hydrogenation; Chiral building blocks; Enzymatic resolution; Fluorinated amino acids; Transition metal catalysis

Indexed keywords

ENZYME; FLUORINE;

CATALYSIS; CHIRALITY; CONFERENCE PAPER; ENZYME SYNTHESIS; FLUORINATION; HYDROGENATION; PHASE TRANSITION; SUBSTITUTION REACTION;

EID: 1842785060     PISSN: 00094293     EISSN: None     Source Type: Journal    
DOI: 10.2533/000942904777678127     Document Type: Conference Paper

References (14)

1. a) T. Sonke, B. Kaptein, W.H.J. Boesten, Q.B. Broxterman, J. Kamphuis, F. Formaggio, C. Toniolo, F.P.J.T. Rutjes, H.E. Schoemaker, in 'Stereoselective Biocatalysis', Ed. R.N. Patel, Marcel Dekker, New York, 2000, p. 23;
2. b) H.E. Schoemaker, W.H.J. Boesten, Q.B. Broxterman, E.C. Roos, B. Kaptein, W.J.J. van den Tweel, J. Kamphuis, F.P.J.T. Rutjes, Chimia 1997, 51, 308;
3. c) H.E. Schoemaker, W.H.J. Boesten, B. Kaptein, E.C. Roos, Q.B. Broxterman, W.J.J. van den Tweel, J. Kamphuis, Acta Chem. Scand. 1996, 50, 225.
4. a) V.H.M. Elferink, D. Breitgoff, M. Kloosterman, J. Kamphuis, W.J.J. van den Tweel, E.M. Meijer, Recl. Trav. Chim. Pays-Bas 1991, 110, 63;
5. b) W.H.J. Boesten, German Patent DE 2526594, 1976.
6. B. Kaptein, W.H.J. Boesten, Q.B. Broxterman, P.J.H. Peters, H.E. Schoemaker, J. Kamphuis, Tedrahedron: Asymmetry 1993, 4, 1113.
7. W.J.J. van den Tweel, T.J.G.M. van Dooren, P.H. de Jonge, B. Kaptein, A.L.L Duchateau, J. Kamphuis, Appl. Microbiol. Biot. 1993, 39, 296.
8. a) M. van den Berg, A.J. Minnaard, R.M. Haak, M. Leeman, E.P. Schudde, A. Meetsma, B.L. Feringa, A.H.M. de Vries, C.E.P. Maljaars, C.E. Willans, D. Hyett, J.A.F. Boogers, H.J.W. Henderickx, J.G. de Vries, Adv. Synth. Catal. 2003, 345, 308;
9. b) M. van den Berg, R.M. Haak, A.J. Minnaard, A.H.M. de Vries, J.G. de Vries, B.L. Feringa, Adv. Synth. Catal. 2002, 344, 1003.
10. M. van den Berg, A.J. Minnaard, B. Feringa, J.G. de Vries (DSM NV), WO 02/04466-A2, 2002.
11. a) L.B. Wolf, T. Sonke, K.C.M.F. Tjen, B. Kaptein, Q.B. Broxterman, H.E. Schoemaker, F.P.J.T. Rutjes, Adv. Synth. Catal. 2001, 343, 662;
12. b) F.P.J.T. Rutjes, L.B. Wolf, H.E. Schoemaker, J. Chem. Soc. Perkin Trans. 1 2000, 4197.
13. S. Torrii, H. Okumoto, T. Kotani, F. Akahoshi, Chem. Lett. 1989, 1971.
14. M.P. Jennings, E.A. Cork, P.V. Ramachandran, J. Org. Chem. 2000, 65, 8763.