Effects of stratification in the analysis of affected-sib-pair data: Benefits and costs

American Journal of Human Genetics

Volumn 66, Issue 2, 2000, Pages 567-575

  Leal, Suzanne M ^a   Ott, Jurg ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COST BENEFIT ANALYSIS; DATA ANALYSIS; GENE LOCUS; GENETIC ANALYSIS; GENETIC LINKAGE; HUMAN; PRIORITY JOURNAL; SIBLING;

EID: 0033912327     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/302748     Document Type: Article

References (8)

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2. Cordell HJ, Todd JA, Bennett ST, Kawaguchi Y, Farrall M (1995) Two-locus maximum lod score analysis of a multi-factorial trait: joint consideration of IDDM2 and IDDM4 with IDDM1 in type 1 diabetes. Am J Hum Gener 57: 920-934
3. Mein CA, Esposito L, Dunn MG, Johnson GCL, Timms AE, Goy JV, Smith AN, et al (1998) A search for type 1 diabetes susceptibility genes in families from the United Kingdom. Nat Genet 19:297-300
4. Ott J (1999) Analysis of human genetic linkage, 3d ed. Johns Hopkins University Press, Baltimore
5. Pericak-Vance MA, Bebout JL, Gaskell PC Jr, Yamaoka LH, Hung WY, Alberts MJ, Walker AP, et al (1991) Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage. Am J Hum Genet 48:1034-1050
6. Risch N (1990a) Linkage strategies for genetically complex traits. I. Multilocus models. Am J Hum Genet 46:222-228
7. -(19906) Linkage strategies for genetically complex traits. II. The power of affected relative pairs. Am J Hum Genet 46:229-241
8. Russell MB, Rasmussen BK, Fenger K, Olesen J (1996) Migraine without aura and migraine with aura are distinct clinical entities: a study of four hundred and eighty-four male and female migraineurs from the general population. Cephalalgia 16:239-245