Three-dimensional porous network structure developed in hydroxyapatite-based nanocomposites containing enzyme pretreated silk fibroin

Journal of Nanoparticle Research

Volumn 6, Issue 1, 2004, Pages 91-98

  Wang, Li ^a   Nemoto, Rei ^a   Senna, Mamoru ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

Crystallographic properties; Enzyme pretreatment of silk fibroin; Hydroxyapatite based nanocomposite; Porosity; Three dimensional network; Vickers microhardness

Indexed keywords

ENZYME; HYDROXYAPATITE; PROTEINASE K; SILK FIBROIN;

ANISOTROPY; ARTICLE; BINDING AFFINITY; CHEMICAL MODIFICATION; COMPOSITE MATERIAL; CROSS LINKING; CRYSTALLIZATION; CRYSTALLOGRAPHY; ENZYME MODIFICATION; HARDNESS; NANOPARTICLE; POROSITY; STRUCTURE ANALYSIS;

EID: 1842708987     PISSN: 13880764     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NANO.0000023228.49670.86     Document Type: Article

References (25)

1. Bigi A., S. Panzavolta & N. Roveri, 1998. Hydroxyapatite-gelatin films: A structural and mechanical characterization. Biomaterials 19, 739-744.
2. Chang M.C., T. Ikoma, M. Kikuchi & J. Tanaka, 2002. The cross-linkage effect of hydroxyapatite/collagen nanocomposites on a self-organization phenomenon. J. Mater. Sci. Mater. Med. 13, 993-997.
3. Chang M.C., C.C. Ko & W.H. Douglas, 2003. Preparation of hydroxyapatite-gelatin nanocomposite. Biomaterials 24, 2853-2862.
4. Chen F., Z.C. Wang & C.J. Lin, 2002. Preparation and characterization of nano-sized hydroxyapatite particles and hydroxyapatite/chitosan nano-composite for use in biomedical materials. Mater. Lett. 57, 858-861.
5. Du C., F.Z. Cui, W. Zhang, Q.L. Feng, X.D. Zhu & K. De Groot, 2000. Formation of calcium phosphate/collagen composites through mineralization of collagen matrix. J. Biomed. Mater. Res. 50, 518-527.
6. Evans G.P., J.C. Behiri, J.D. Currey & W. Bonfield, 1990. Micro-hardness and Young's modulus in cortical bone exhibiting a wide range of mineral volume fractions, and in a bone analogue. J. Mater. Sci. Mater. Med. 1, 38-43.
7. Freddi G., P. Monti, M. Nagura, Y. Gotoh & M. Tsukada, 1997. Structure and molecular conformation of tussah silk fibroin films: Effect of heat treatment. J. Polym. Sci. B: Polym. Phys. 35, 841-847.
8. Furuzono T., T. Taguchi, A. Kishida, M. Akashi & Y. Tamada, 2000. Preparation and characterization of apatite deposited on silk fabric using an alternate soaking process. J. Biomed. Mater. Res. 50, 344-352.
9. Ikoma T., A. Yamazakai, S. Nakamura & M. Akao, 1999. Preparation and structure refinement of monoclinic hydroxyapatite. J. Solid State Chem. 144, 272-276.
10. Ito M., Y. Hidaka, M. Nakajima, H. Yagasaki & A.H. Kafrawy, 1999. Effect of hydroxyapatite content on physical properties and connective tissue reactions to a chitosan-hydroxyapatite composite membrane. J. Biomed. Mater. Res. 45, 204-208.
11. Izumi F. & T. Ikeda, 2000. A Rietveld-analysis program RIETAN-98 and its applications to zeolites. Mater. Sci. Forum 321, 198-203.
12. Kikuchi M., S. Itoh, S. Ichinose, K. Shinomiya & J. Tanaka, 2001. Self-organization mechanism in a bone-like hydroxyapatite/collagen nanocomposite synthesized in vitro and its biological reaction in vivo. Biomaterials 22, 1705-1711.
13. Liu D.M., 1996. Fabrication and characterization of porous hydroxyapatite granules. Biomaterials 17, 1955-1957.
14. Park S.J., K. Y. Lee, W.S. Ha & S.Y. Park, 1999. Structural changes and their effect on mechanical properties of silk fibroin/chitosan blends. J. Appl. Polym. Sci. 74, 2571-2575.
15. Petsch D., W.D. Deckwer & F.B. Anspach, 1998. Proteinase K digestion of proteins improves detection of bacterial endotoxins by the limulus amebocyte lysate assay: Application for endotoxin removal from cationic proteins. Anal. Biochem. 259, 42-47.
16. Rhee S.H. & J. Tanaka, 2002. Self-assembly phenomenon of hydroxyapatite nanocrystals on chondroitin sulfate. J. Mater. Sci.: Mater. Med. 13, 597-600.
17. Sepulveda P., J.G.P. Binner, S.O. Rogero, O.Z. Higa & J.C. Bressiani, 2000. Production of porous hydroxyapatite by the gel-casting of foams and cytotoxic evaluation. J. Biomed. Mater. Res. 50, 27-34.
18. Tamai N., A. Myoui, T. Tomita, T. Nakase, J. Tanaka & T. Ochi, 2002. Novel hydroxyapatite ceramics with an interconnective porous structure exhibit superior osteoconduction in vivo. J. Biomed. Mater. Res. 59, 110-117.
19. Tampieri A., G. Celotti, S. Sprio, A. Delcogliano & S. Franzese, 2001. Porosity-graded hydroxyapatite ceramics to replace natural bone. Biomaterials 22, 1365-1370.
20. TenHuisen K.S. & P.W. Brown, 1994. The formation of hydroxyapatite-gelatin composites at 38°C. J. Biomed. Mater. Res. 28, 27-33.
21. Wang L., R. Nemoto & M. Senna, 2002. Microstructure and chemical states of hydroxyapatite/silk fibroin nanocomposites synthesized via a wet-mechanochemical route. J. Nanoparticle Res. 4, 535-540.
22. Wang L., R. Nemoto & M. Senna, 2003a. Changes in microstructure and physico-chemical properties of hydroxyapatite-silk fibroin nanocomposite with varying silk fibroin content. J. Eur. Ceram. Soc. (in press).
23. Wang L., R. Nemoto & M. Senna, 2003b. Effects of alkali pretreatment of silk fibroin on microstructure and properties of hydroxyapatite-silk fibroin nanocomposite. J. Mater. Sci.: Mater. Med. (in press).
24. Yamaguchi I., K. Tokuchi, H. Fukuzaki, Y. Koyama, K. Takakuda, H. Monma & J. Tanaka, 2001. Preparation and microstructure analysis of chitosan/hydroxyapatite nanocomposites. J. Biomed. Mater. Res. 55, 20-27.
25. Zhao F., Y.J. Yin, W.W. Lu, J.C. Leong, W.Y. Zhang, J.Y. Zhang, M.F. Zhang & K.D. Yao, 2002. Preparation and histological evaluation of biomimetic three-dimensional hydroxyapatite/chitosan-gelatin network composite scaffolds. Biomaterials 23, 3227-3234.