Production of porous hydroxyapatite by the gel-casting of foams and cytotoxic evaluation

Journal of Biomedical Materials Research

Volumn 50, Issue 1, 2000, Pages 27-34

  Sepulveda, P ^a,c   Binner, J G P ^d   Rogero, S O ^b   Higa, O Z ^b   Bressiani, J C ^b  

^a FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^b INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES   (Brazil)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d BRUNEL UNIVERSITY   (United Kingdom)

Author keywords

Bone implants; Cytotoxicity; Gel cast foams; Hydroxyapatite; Porous ceramics

Indexed keywords

HYDROXYAPATITE;

ARTICLE; BIOCOMPATIBILITY; CYTOTOXICITY; FOAM; GEL; IMPLANT; PLASTER CAST; POROSITY; PROSTHESIS MATERIAL;

ANIMALS; CELL SURVIVAL; CERAMICS; CHO CELLS; COMPRESSIVE STRENGTH; CRICETINAE; DURAPATITE; GELS; HEAT; MICROSCOPY, ELECTRON; MICROSCOPY, ELECTRON, SCANNING;

CERAMIC MATERIALS; DENSITY (SPECIFIC GRAVITY); FOAMS; MONOMERS; PHOSPHATE MINERALS; POLYMERIZATION; POROUS MATERIALS; TOXICITY;

GEL-CASTING; HYDROXYAPATITE;

IMPLANTS (SURGICAL);

EID: 0033622847     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4636(200004)50:1<27::AID-JBM5>3.0.CO;2-6     Document Type: Article

References (15)

1. Liu DM. Porous hydroxyapatite bioceramics. In: Liu, DM, editor. Key engineering materials. Vol. 115. Uetikon-Zuerich, Switzerland: Trans Tech Publications; 1996, p 209-232.
2. Fabri M, Celotti GC, Ravaglioli A. Hydroxyapatite-based porous aggregates: Physico-chemical nature, structure, texture and architecture. Biomaterials 1995;16:225-228.
3. Arita IH, Wilkison DS, Mondragon MA, Castano VM. Chemistry and sintering behaviour of thin hydroxyapatite ceramics with controlled porosity. Biomaterials 1995;16:403-408.
4. th International Symposium on Ceramics in Medicine, Turku, Finland, July 1994. Oxford: Butterworth-Heinemann Ltd. 446 p.
5. Constantino PD, Friedman CD. Synthetic bone graft substitutes. Craniofacial skeletal augmentation and replacement. Otolaryngol Clin N A 1994;27(5):1037-1074.
6. Sepulveda P. Gelcasting foams for porous ceramics. Ceram Bull 1997;76(10):61-65.
7. Sepulveda PAI, Binner JGP. Processing of cellular ceramics by foaming and in situ polymerization of organic monomers. J Eur Ceram Soc 1999;19:2059-2066.
8. International Standard: Biological evaluation of medical devices. Part 5. Tests for cytotoxicity: In vitro methods. ISO 1993; 10:993-995.
9. nd ed. New York: John Wiley & Sons, Inc.; 1989. p. 277-303.
10. rd ed. New York: John Wiley & Sons, Inc.; 1991. 768 p.
11. Janney MA, Omatete OO. Method for molding ceramic powders using water-based gel casting. US patent no. 5028362; 1991.
12. Young AC, Omatete OO, Janney MA, Menchhofer PA. Gelcasting of alumina. J Am Ceram Soc 1991;74(3):612-618.
13. Miquel JL, Facchini L, Legrand AP, Key C, Lemaitre J. Solid state NMR to study calcium phosphate ceramics. Coll Surfaces 1990;45:427-433.
14. Liu DM. Influence of porosity and pore size on the compressive strength of porous hydroxyapatite ceramic. Ceram Int 1997;23:135-139.
15. Ravaglioli A, Krajewski A. Bioceramics: Materials, properties, applications. London: Chapman and Hall; 1992. 432 p.