Treatment of obese non-insulin-dependent diabetic adolescents with metformin. A report on 3 cases;Metformin zur behandlung des primär nicht insulinpflichtigen diabetes mellitus bei adipösen jugendlichen. Bericht über 3 fälle

Monatsschrift fur Kinderheilkunde

Volumn 150, Issue 6, 2002, Pages 756-760

  Seewi, O ^a,b   Even, G ^a   Schonau E ^a  

^a UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Childhood diabetes; Metformin; Obesity; Type 1 diabetes; Type 2 diabetes

Indexed keywords

HEMOGLOBIN A1C; METFORMIN;

ADOLESCENT; ARTICLE; CASE REPORT; DIABETES CONTROL; DIABETIC DIET; DRUG EFFICACY; FOLLOW UP; HEMOGLOBIN DETERMINATION; HUMAN; LOW CALORY DIET; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRADER WILLI SYNDROME; TREATMENT OUTCOME; WEIGHT GAIN;

EID: 1842677346     PISSN: 00269298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00112-001-0347-1     Document Type: Article

References (24)

1. Burke JP, Hale DE, Hazuda HP, Stern MP (1999) A quantitative scale of acanthosis nigricans. Diabetes Care 22: 1655-1659
2. Dabelea D, Pettitt DJ, Jones KL, Arslanian SA (1999) Type 2 diabetes mellitus in minority children and adolescents. Endocrinol Metab Clin North Am 28: 709-729
3. Ehtisham S, Barrett TG, Shaw NJ (2000) Type 2 diabetes mellitus in UK children - an emerging problem. Diabet Med 17: 867-871
4. Fajans SS, Floyd JC, Pek S, Conn JW (1973) Studies on the natural history of asymptomatic diabetes in young people. Metabolism 22: 327-334
5. Fuessl HS, Goebel FD (1983) Klinische Variabilität des autosomal-dominanten Diabetes des Jugendalters (MODY). Dtsch Med Wochenschr 108: 1868-1871
6. Hermann LS, Melander A (1997) Biguanides - basic aspects and clinical use. In: Alberti KGMM, Zimmet P, DeFronzo RA, Keen H (eds) International textbook of diabetes, 2nd edn. Wiley & Sons, Chichester, pp 841-864
7. Hesse V (1997) Wachstum und Reifung. Körpermassenindex (KMI) von Mädchen und Jungen. In: Meng W, Ziegler R(Hrsg)Endokrinologie. Fischer, Jena, S. 105-130, 632
8. Holman RR, Cull CA, Stratton IM, Turner RC for the UK Prospective Diabetes Study Group (1995) Six-year randomized controlled trial of diet, sulphonylurea, insulin, and metformin therapy in 270 subjects at risk for diabetes. Diabet Med [Suppl 1] 12: S5
9. Jockenhövel F (1996) Männlicher Hypogonadismus. In: Allolio B, Schulte HM (Hrsg) Praktische Endokrinologie. Urban & Schwarzenberg, München Wien Baltimore, S 361-380
10. Jones K, Arslanian S, McVie R, Tomlinson M, Park JS, Study Group Metformin Pediatric (2000) Metformin improves glycemic control in children with type-2 diabetes. Diabetes [Suppl 1] 49: A75
11. Kerner W, Fuchs C, Redaelli M et al. (2001) Definition, Klassifikation und Diagnostik des Diabetes mellitus. In: Scherbaum WA, Lauterbach KW, Joost HH (Hrsg) Evidenzbasierte Diabetes-Leitlinien DDG. Deutsche Diabetes-gesellschaft, ISBN 3-933740-07-X
12. Lee PJ, Granston I, Amiel SA, O'Rahilly S, Aynsley Green A (1997) Effect of metformin on glucose disposal and hyperinsulinaemia in a 14-year old boy with acanthosis nigricans. Horm Res 48: 88-92
13. Lindgren AC, Ritzen EM (1999) Five years of growth hormone treatment in children with Prader-Willi-syndrome. Acta Paediatr [Suppl 433] 88: 109-111
14. Matyka KA, Beards F, Appleton M, Ellard S, Hattersley A, Dunger DB (1998) Genetic testing for maturity onset diabetes of the young in childhood hyperglycaemia. Arch Dis Child 78: 552-554
15. Ng GYT, Burren CP (2000) Type 2 diabetes in adolescence - unearthed at the time of registration with the general practitioner. Pract Diab Int 17: 273-274
16. Panzram G (1984) Nicht-insulinabhängiger Diabetes im frühen Lebensalter. Dtsch Med Wochenschr 109: 733-734
17. Panzram G, Adolph W (1983) Ergebnisse einer Populationsstudie über den nicht-insulinabhängigen Diabetes mellitus im Kindes- und Jugendalter. Schweiz Med Wochenschr 113: 779-784
18. Rajghandari SM, Tesfaye S, Ward JD (1999) Acute diabetic ketoacidosis precipitated by substitution of insulin in type-2 diabetes. Pract Diabet Int 16: 253-254
19. Robinson C, Yee BYF, Kelly AP (2000) Symmetrical black plaques on the toes. Arch Dermatol 36: 791
20. Roeleveld-Versteegh ABC, Jansen M, Vroede M de (1998) Een 12-jarig meisje met diabetes mellitus type 2. Ned Tijdschr Geneeskd 142: 2256-2258
21. Rosenbloom A, Joe JR, Young RS, Winter WE (1999) Emerging epidemic of type 2 diabetes in youth. Diabetes Care 22: 345-354
22. Turner RC, Holman RR, Stratton IM, Cull CA, Matthews DR, Manley SE, Frighi V, Wright D, Neil A, Kohner E, McElroy H, Fox C, Madden D (1998) Effect of intensive blood-glucose control with metformin on complications in overweight patients with type-2 diabetes (UKPDS 34). Lancet 352: 854-865
23. Weyer C, Tataranni PA, Bogardus C, Pratley RE (2001) Insulin resistance and insulin secretory dysfunction are independent predictors of worsening of glucose tolerance during each stage of type-2 diabetes development. Diabetes Care 24: 89-94
24. Zipf WB (1999) Glucose homeostasis in Prader-Willi-syndrome and potential implications of growth hormonetherapy. Acta Paediatr [Suppl 433] 88: 115-117