-
2
-
-
0030896270
-
Increased substance P responses in dorsal root ganglia and intestinal macrophages during Clostridium difficile toxin A enteritis in rats
-
Castagliuolo I., Keates A.C., Qiu B., Kelly C.P., Nikulasson S., Leeman S.E., Pothoulakis C. Increased substance P responses in dorsal root ganglia and intestinal macrophages during Clostridium difficile toxin A enteritis in rats. Proc. Natl. Acad. Sci. U.S.A. 94:1997;4788-4793.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 4788-4793
-
-
Castagliuolo, I.1
Keates, A.C.2
Qiu, B.3
Kelly, C.P.4
Nikulasson, S.5
Leeman, S.E.6
Pothoulakis, C.7
-
3
-
-
0032523213
-
Neurokinin-1 (NK-1) receptor is required in Clostridium difficile-induced enteritis
-
Castagliuolo I., Riegler M., Pasha A., Nikulasson S., Lu B., Gerard C., Gerard N.P., Pothoulakis C. Neurokinin-1 (NK-1) receptor is required in Clostridium difficile-induced enteritis. J. Clin. Invest. 101:1998;1547-1550.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1547-1550
-
-
Castagliuolo, I.1
Riegler, M.2
Pasha, A.3
Nikulasson, S.4
Lu, B.5
Gerard, C.6
Gerard, N.P.7
Pothoulakis, C.8
-
4
-
-
0030777012
-
The capsaicin receptor: A heat-activated ion channel in the pain pathway
-
Caterina M.J., Schumacher M.A., Tominaga M., Rosen T.A., Levine J.D., Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature. 389:1997;816-824.
-
(1997)
Nature
, vol.389
, pp. 816-824
-
-
Caterina, M.J.1
Schumacher, M.A.2
Tominaga, M.3
Rosen, T.A.4
Levine, J.D.5
Julius, D.6
-
5
-
-
0027272721
-
The effect of intrathecal administration of RP67580, a potent neurokinin 1 antagonist on nociceptive transmission in the rat spinal cord
-
Chapman V., Dickenson A.H. The effect of intrathecal administration of RP67580, a potent neurokinin 1 antagonist on nociceptive transmission in the rat spinal cord. Neurosci. Lett. 157:1993;149-152.
-
(1993)
Neurosci. Lett.
, vol.157
, pp. 149-152
-
-
Chapman, V.1
Dickenson, A.H.2
-
6
-
-
0028005748
-
Neuroimmune signaling in regulation of intestinal ion transport
-
Cooke H.J. Neuroimmune signaling in regulation of intestinal ion transport. Am. J. Physiol. 266:1994;G167-G178.
-
(1994)
Am. J. Physiol.
, vol.266
, pp. 167-G178
-
-
Cooke, H.J.1
-
7
-
-
0031003678
-
Substance P as a mediator of colonic secretory reflexes
-
Cooke H.J., Sidhu M., Fox P., Wang Y.Z., Zimmermann E.M. Substance P as a mediator of colonic secretory reflexes. Am. J. Physiol. 272:1997;G238-G245.
-
(1997)
Am. J. Physiol.
, vol.272
, pp. 238-G245
-
-
Cooke, H.J.1
Sidhu, M.2
Fox, P.3
Wang, Y.Z.4
Zimmermann, E.M.5
-
8
-
-
0027220996
-
Pharmacological characterisation of neurokinin receptors mediating anion secretion in rat descending colon mucosa
-
Cox H.M., Tough I.R., Grayson K., Yarrow S. Pharmacological characterisation of neurokinin receptors mediating anion secretion in rat descending colon mucosa. Naunyn-Schmiedeberg's Arch. Pharmacol. 348:1993;172-177.
-
(1993)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.348
, pp. 172-177
-
-
Cox, H.M.1
Tough, I.R.2
Grayson, K.3
Yarrow, S.4
-
9
-
-
0034600276
-
Effects of TAK-637, a tachykinin receptor antagonist, on the micturition reflex in guinea pigs
-
Doi T., Kamo I., Imai S., Okanishi S., Ikeura Y., Natsugari H. Effects of TAK-637, a tachykinin receptor antagonist, on the micturition reflex in guinea pigs. Eur. J. Pharmacol. 395:2000;241-246.
-
(2000)
Eur. J. Pharmacol.
, vol.395
, pp. 241-246
-
-
Doi, T.1
Kamo, I.2
Imai, S.3
Okanishi, S.4
Ikeura, Y.5
Natsugari, H.6
-
10
-
-
0033695164
-
Novel targets for the pharmacotherapy of diarrhoea: A view for the millennium
-
Farthing M.J.G. Novel targets for the pharmacotherapy of diarrhoea: a view for the millennium. J. Gastroenterol. Hepatol. 15:2000;G38-G45.
-
(2000)
J. Gastroenterol. Hepatol.
, vol.15
, pp. 38-G45
-
-
Farthing, M.J.G.1
-
11
-
-
0033040772
-
Different tachykinin receptors mediate chloride secretion in the distal colon through activation of submucosal neurones
-
Frieling T., Dobreva G., Weber E., Becker K., Rupprecht C., Neunlist M., Schemann M. Different tachykinin receptors mediate chloride secretion in the distal colon through activation of submucosal neurones. Naunyn-Schmiedeberg's Arch. Pharmacol. 359:1999;71-79.
-
(1999)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.359
, pp. 71-79
-
-
Frieling, T.1
Dobreva, G.2
Weber, E.3
Becker, K.4
Rupprecht, C.5
Neunlist, M.6
Schemann, M.7
-
12
-
-
0033855333
-
Neurokinin-1 receptor expression in inflammatory bowel disease: Molecular quantitation and localisation
-
Goode T., O'Connell J., Anton P., Wong H., Reeve J., O'Sullivan G.C., Collins J.K., Shanahan F. Neurokinin-1 receptor expression in inflammatory bowel disease: molecular quantitation and localisation. Gut. 47:2000;387-396.
-
(2000)
Gut
, vol.47
, pp. 387-396
-
-
Goode, T.1
O'connell, J.2
Anton, P.3
Wong, H.4
Reeve, J.5
O'sullivan, G.C.6
Collins, J.K.7
Shanahan, F.8
-
14
-
-
0025241013
-
Effects of substance P and vasoactive intestinal polypeptide on contractile activity and epithelial transport in the ferret jejunum
-
Greenwood B., Doolittle T., See N.A., Koch T.R., Dodds W.J., Davison J.S. Effects of substance P and vasoactive intestinal polypeptide on contractile activity and epithelial transport in the ferret jejunum. Gastroenterology. 98:1990;1509-1517.
-
(1990)
Gastroenterology
, vol.98
, pp. 1509-1517
-
-
Greenwood, B.1
Doolittle, T.2
See, N.A.3
Koch, T.R.4
Dodds, W.J.5
Davison, J.S.6
-
15
-
-
0025871477
-
Capsaicin: Cellular targets, mechanisms of action, and selectivity for thin sensory neurons
-
Holzer P. Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmacol. Rev. 43:1991;143-201.
-
(1991)
Pharmacol. Rev.
, vol.43
, pp. 143-201
-
-
Holzer, P.1
-
16
-
-
0030996201
-
Tachykinins in the gut: Part II. Roles in neural excitation, secretion and inflammation
-
Holzer P., Holzer-Petsche U. Tachykinins in the gut: Part II. Roles in neural excitation, secretion and inflammation. Pharmacol. Ther. 73:1997;219-263.
-
(1997)
Pharmacol. Ther.
, vol.73
, pp. 219-263
-
-
Holzer, P.1
Holzer-Petsche, U.2
-
19
-
-
0028883674
-
Changes in substance P-immunoreactive innervation of human colon associated with ulcerative colitis
-
Keranen U., Kiviluoto T., Jarvinen H., Back N., Kivilaakso E., Soinila S. Changes in substance P-immunoreactive innervation of human colon associated with ulcerative colitis. Dig. Dis. Sci. 40:1995;2250-2258.
-
(1995)
Dig. Dis. Sci.
, vol.40
, pp. 2250-2258
-
-
Keranen, U.1
Kiviluoto, T.2
Jarvinen, H.3
Back, N.4
Kivilaakso, E.5
Soinila, S.6
-
20
-
-
0025098055
-
Tachykinin-induced anion secretion in guinea pig distal colon: Role of neural and inflammatory mediators
-
Kuwahara A., Cooke H.J. Tachykinin-induced anion secretion in guinea pig distal colon: role of neural and inflammatory mediators. J. Pharmacol. Exp. Ther. 252:1990;1-7.
-
(1990)
J. Pharmacol. Exp. Ther.
, vol.252
, pp. 1-7
-
-
Kuwahara, A.1
Cooke, H.J.2
-
21
-
-
0030664860
-
Cellular pathways mediating tachykinin-evoked secretomotor responses in guinea pig ileum
-
MacNoughton W., Moore B., Vanner S. Cellular pathways mediating tachykinin-evoked secretomotor responses in guinea pig ileum. Am. J. Physiol. 273:1997;G1127-G1134.
-
(1997)
Am. J. Physiol.
, vol.273
, pp. 1127-G1134
-
-
Macnoughton, W.1
Moore, B.2
Vanner, S.3
-
22
-
-
0029123521
-
Differential expression of substance P receptors in patients with Crohn's disease and ulcerative colitis
-
Mantyh C.R., Vigna S.R., Bollinger R.R., Mantyh P.W., Maggio J.E., Pappas T.N. Differential expression of substance P receptors in patients with Crohn's disease and ulcerative colitis. Gastroenterology. 109:1995;850-860.
-
(1995)
Gastroenterology
, vol.109
, pp. 850-860
-
-
Mantyh, C.R.1
Vigna, S.R.2
Bollinger, R.R.3
Mantyh, P.W.4
Maggio, J.E.5
Pappas, T.N.6
-
23
-
-
0029852142
-
Substance P activation of enteric neurons in response to intraluminal Clostridium difficile toxin A in the rat ileum
-
Mantyh C.R., Pappas T.N., Lapp J.A., Washington M.K., Neville L.M., Ghilardi J.R., Rogers S.D., Mantyh P.W., Vigna S.R. Substance P activation of enteric neurons in response to intraluminal Clostridium difficile toxin A in the rat ileum. Gastroenterology. 111:1996;1272-1280.
-
(1996)
Gastroenterology
, vol.111
, pp. 1272-1280
-
-
Mantyh, C.R.1
Pappas, T.N.2
Lapp, J.A.3
Washington, M.K.4
Neville, L.M.5
Ghilardi, J.R.6
Rogers, S.D.7
Mantyh, P.W.8
Vigna, S.R.9
-
24
-
-
0026601086
-
Immunocytochemical localization of vasoactive intestinal peptide and substance in the colon from normal subjects and patients with inflammatory bowel disease
-
Mazumdar S., Das K.M. Immunocytochemical localization of vasoactive intestinal peptide and substance in the colon from normal subjects and patients with inflammatory bowel disease. Am. J. Gastroenterol. 87:1992;176-181.
-
(1992)
Am. J. Gastroenterol.
, vol.87
, pp. 176-181
-
-
Mazumdar, S.1
Das, K.M.2
-
25
-
-
0022599434
-
Substance P-induced intestinal secretion of water and electrolytes
-
McFadden D., Zinner M., Jaffe B.M. Substance P-induced intestinal secretion of water and electrolytes. Gut. 27:1986;267-272.
-
(1986)
Gut
, vol.27
, pp. 267-272
-
-
Mcfadden, D.1
Zinner, M.2
Jaffe, B.M.3
-
26
-
-
0035010310
-
Potent NK1 antagonism by SR-140333 reduces rat colonic secretory response to immunocyte activation
-
Moriarty D., Selve N., Baird A.W., Goldhill J. Potent NK1 antagonism by SR-140333 reduces rat colonic secretory response to immunocyte activation. Am. J. Physiol. 280:2001;C852-C858.
-
(2001)
Am. J. Physiol.
, vol.280
, pp. 852-C858
-
-
Moriarty, D.1
Selve, N.2
Baird, A.W.3
Goldhill, J.4
-
27
-
-
0033598446
-
1 receptor antagonists: Synthesis, antagonistic activity, and effects on bladder functions
-
1 receptor antagonists: synthesis, antagonistic activity, and effects on bladder functions. J. Med. Chem. 42:1999;3982-3993.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 3982-3993
-
-
Natsugari, H.1
Ikeura, Y.2
Kamo, I.3
Ishimaru, T.4
Ishichi, Y.5
Fujishima, A.6
Tanaka, T.7
Kasahara, F.8
Kawada, M.9
Doi, T.10
-
28
-
-
0034926074
-
Effects of TAK-637, a novel neurokinin-1 receptor antagonist, on colonic function in vivo
-
Okano S., Nagaya H., Ikeura Y., Natsugari H., Inatomi N. Effects of TAK-637, a novel neurokinin-1 receptor antagonist, on colonic function in vivo. J. Pharmacol. Exp. Ther. 298:2001;559-564.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.298
, pp. 559-564
-
-
Okano, S.1
Nagaya, H.2
Ikeura, Y.3
Natsugari, H.4
Inatomi, N.5
-
29
-
-
0023277915
-
Evidence for substance P as a functional neurotransmitter in guinea pig small intestinal mucosa
-
Perdue M.H., Galbraith R., Davison J.S. Evidence for substance P as a functional neurotransmitter in guinea pig small intestinal mucosa. Regul. Pept. 18:1987;63-74.
-
(1987)
Regul. Pept.
, vol.18
, pp. 63-74
-
-
Perdue, M.H.1
Galbraith, R.2
Davison, J.S.3
-
30
-
-
0028013431
-
CP-96,345, a substance P antagonist, inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin
-
Pothoulakis C., Castagliuolo I., LaMont J.T., Jaffer A., O'Keane J.C., Snider R.M., Leeman S.E. CP-96,345, a substance P antagonist, inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin. Proc. Natl. Acad. Sci. U.S.A. 91:1994;947-951.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 947-951
-
-
Pothoulakis, C.1
Castagliuolo, I.2
Lamont, J.T.3
Jaffer, A.4
O'keane, J.C.5
Snider, R.M.6
Leeman, S.E.7
-
31
-
-
0026667116
-
Neurokinin 1 receptors mediate substance P-induced changes in ion transport in guinea-pig ileum
-
Reddix R.A., Cooke H.J. Neurokinin 1 receptors mediate substance P-induced changes in ion transport in guinea-pig ileum. Regul. Pept. 39:1992;215-225.
-
(1992)
Regul. Pept.
, vol.39
, pp. 215-225
-
-
Reddix, R.A.1
Cooke, H.J.2
-
32
-
-
0033000344
-
Effects of substance P on human colonic mucosa in vitro
-
Riegler M., Castagliuolo I., So P.T., Lotz M., Wang C., Wlk M., Sogukoglu T., Cosentini E., Bischof G., Hamilton G., Teleky B., Wenzl E., Matthews J.B., Pothoulakis C. Effects of substance P on human colonic mucosa in vitro. Am. J. Physiol. 276:1999;G1473-G1483.
-
(1999)
Am. J. Physiol.
, vol.276
, pp. 1473-G1483
-
-
Riegler, M.1
Castagliuolo, I.2
So, P.T.3
Lotz, M.4
Wang, C.5
Wlk, M.6
Sogukoglu, T.7
Cosentini, E.8
Bischof, G.9
Hamilton, G.10
Teleky, B.11
Wenzl, E.12
Matthews, J.B.13
Pothoulakis, C.14
-
33
-
-
0035087476
-
1 tachykinin receptor on muscle and epithelia in guinea pig intestine
-
1 tachykinin receptor on muscle and epithelia in guinea pig intestine. Gastroenterology. 120:2001;1140-1151.
-
(2001)
Gastroenterology
, vol.120
, pp. 1140-1151
-
-
Southwell, B.R.1
Furness, J.B.2
-
34
-
-
0025997478
-
Molecular cloning, structural characterization and functional expression of the human substance P receptor
-
Takeda Y., Chou K.B., Takeda J., Sachais B.S., Krause J.E. Molecular cloning, structural characterization and functional expression of the human substance P receptor. Biochem. Biophys. Res. Commun. 179:1991;1232-1240.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.179
, pp. 1232-1240
-
-
Takeda, Y.1
Chou, K.B.2
Takeda, J.3
Sachais, B.S.4
Krause, J.E.5
-
35
-
-
0028847772
-
Capsaicin-sensitive afferent nerves activate submucosal secretomotor neurons in guinea pig ileum
-
Vanner S., MacNaughton W.K. Capsaicin-sensitive afferent nerves activate submucosal secretomotor neurons in guinea pig ileum. Am. J. Physiol. 269:1995;G203-G209.
-
(1995)
Am. J. Physiol.
, vol.269
, pp. 203-G209
-
-
Vanner, S.1
Macnaughton, W.K.2
-
37
-
-
0026071651
-
Neuroimmune regulation of colonic secretion in guinea-pigs
-
Wang Y.-Z., Palmer J.M., Cooke H.J. Neuroimmune regulation of colonic secretion in guinea-pigs. Am. J. Physiol. 260:1991;G307-G314.
-
(1991)
Am. J. Physiol.
, vol.260
, pp. 307-G314
-
-
Wang, Y.-Z.1
Palmer, J.M.2
Cooke, H.J.3
-
38
-
-
0028896680
-
Substance P induces ion secretion in mouse small intestine through effects on enteric nerves and mast cells
-
Wang L., Stanisz A.M., Wershil B.K., Galli S.J., Perdue M.H. Substance P induces ion secretion in mouse small intestine through effects on enteric nerves and mast cells. Am. J. Physiol. 269:1995;G85-G92.
-
(1995)
Am. J. Physiol.
, vol.269
, pp. 85-G92
-
-
Wang, L.1
Stanisz, A.M.2
Wershil, B.K.3
Galli, S.J.4
Perdue, M.H.5
-
39
-
-
0035498664
-
Neural components of distension-evoked secretory responses in the guinea-pig distal colon
-
Weber E., Neunlist M., Schemann M., Frieling T. Neural components of distension-evoked secretory responses in the guinea-pig distal colon. J. Physiol. 536:2001;741-751.
-
(2001)
J. Physiol.
, vol.536
, pp. 741-751
-
-
Weber, E.1
Neunlist, M.2
Schemann, M.3
Frieling, T.4
|