Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a topically acting antiglaucoma sulfonamide

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 9, 2004, Pages 2357-2361

  Abbate, Francesco ^a   Casini, Angela ^b   Scozzafava, Andrea ^b   Supuran, Claudiu T ^b  

^a Bruker Corporation   (United States)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; AMINE; ANTIGLAUCOMA AGENT; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE INHIBITOR; GLUTAMINE; HISTIDINE; ISOENZYME; PHENYL GROUP; PHENYLALANINE; SULFONAMIDE; THREONINE; TRYPTOPHAN; ZINC ION;

ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS HUMOR; ARTICLE; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME STRUCTURE; EYE; FLUORINATION; GLAUCOMA; HYDROGEN BOND; INTRAOCULAR PRESSURE; MOLECULAR INTERACTION; NONHUMAN; X RAY CRYSTALLOGRAPHY;

CARBONIC ANHYDRASE INHIBITORS; CRYSTALLOGRAPHY, X-RAY; GLAUCOMA; HUMANS; ISOENZYMES; MODELS, MOLECULAR; SULFONAMIDES;

ANIMALIA;

EID: 1842639484     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.01.096     Document Type: Article

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